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H. Mizuo · SciRah

Researcher profile · Semantic Scholar

H. Mizuo

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H. Mizuo — researcher profile on SciRah

h-index: 24
Works: 70
Citations: 3,131

Most-cited papers

Sporadic acute or fulminant hepatitis E in Hokkaido, Japan, may be food-borne, as suggested by the presence of hepatitis E virus in pig liver as food.
Y. Yazaki, H. Mizuo, Masaharu Takahashi, T. Nishizawa +3 more
2003Journal of General Virology612 citations Open access
Semantic Scholar
Polyphyletic Strains of Hepatitis E Virus Are Responsible for Sporadic Cases of Acute Hepatitis in Japan
H. Mizuo, Kazuyuki Suzuki, Y. Takikawa, Y. Sugai +7 more
2002Journal of Clinical Microbiology282 citations Open access
Semantic Scholar
Hepatitis E Virus (HEV) Strains in Serum Samples Can Replicate Efficiently in Cultured Cells Despite the Coexistence of HEV Antibodies: Characterization of HEV Virions in Blood Circulation
Masaharu Takahashi, Toshinori Tanaka, Hideyuki Takahashi, Y. Hoshino +10 more
2010Journal of Clinical Microbiology253 citations Open access
Semantic Scholar
Possible risk factors for the transmission of hepatitis E virus and for the severe form of hepatitis E acquired locally in Hokkaido, Japan
H. Mizuo, Y. Yazaki, K. Sugawara, F. Tsuda +3 more
2005Journal of Medical Virology213 citations
Semantic Scholar
Simultaneous Detection of Immunoglobulin A (IgA) and IgM Antibodies against Hepatitis E Virus (HEV) Is Highly Specific for Diagnosis of Acute HEV Infection
Masaharu Takahashi, Shigeyuki Kusakai, H. Mizuo, Kazuyuki Suzuki +6 more
2005Journal of Clinical Microbiology205 citations Open access
Semantic Scholar
Prevalence of Hepatitis E Virus (HEV) Infection in Wild Boars and Deer and Genetic Identification of a Genotype 3 HEV from a Boar in Japan
Hideto Sonoda, M. Abe, Takeshi Sugimoto, Yukihiro Sato +6 more
2004Journal of Clinical Microbiology178 citations Open access
Semantic Scholar
Characterization of Japanese swine and human hepatitis E virus isolates of genotype IV with 99 % identity over the entire genome.
T. Nishizawa, Masaharu Takahashi, H. Mizuo, Haruko Miyajima +2 more
2003Journal of General Virology168 citations
Semantic Scholar
Circular Double-Stranded Forms of TT Virus DNA in the Liver
H. Okamoto, M. Ukita, T. Nishizawa, Junichi Kishimoto +5 more
2000Journal of Virology102 citations Open access
Semantic Scholar
Prolonged Fecal Shedding of Hepatitis E Virus (HEV) during Sporadic Acute Hepatitis E: Evaluation of Infectivity of HEV in Fecal Specimens in a Cell Culture System
Masaharu Takahashi, Toshinori Tanaka, M. Azuma, E. Kusano +6 more
2007Journal of Clinical Microbiology101 citations Open access
Semantic Scholar
Kinetics and mechanism of in vitro uptake of amino-beta-lactam antibiotics by rat small intestine and relation to the intact-peptide transport system.
Emi Nakashima, Akira Tsuji, H. Mizuo, T. Yamana
1984Biochemical Pharmacology98 citations
Semantic Scholar
Clonal origin of human hepatoma determined by integration of hepatitis B virus DNA.
Mariko Esumi, Tomoki Aritaka, M. Arii, Koyu Suzuki +4 more
1986Cancer Research97 citations
Semantic Scholar
Development and Characterization of a Genotype 4 Hepatitis E Virus Cell Culture System Using a HE-JF5/15F Strain Recovered from a Fulminant Hepatitis Patient
Toshinori Tanaka, Masaharu Takahashi, Hideyuki Takahashi, Koji Ichiyama +4 more
2009Journal of Clinical Microbiology92 citations Open access
Semantic Scholar
A549 and PLC/PRF/5 cells can support the efficient propagation of swine and wild boar hepatitis E virus (HEV) strains: demonstration of HEV infectivity of porcine liver sold as food
Hideyuki Takahashi, Toshinori Tanaka, Suljid Jirintai, S. Nagashima +5 more
2011Archives of Virology67 citations
Semantic Scholar
A nationwide survey of hepatitis E virus infection in the general population of Japan
Masaharu Takahashi, Kazuko Tamura, Y. Hoshino, S. Nagashima +7 more
2010Journal of Medical Virology67 citations
Semantic Scholar
Clinical Pharmacokinetic and Pharmacodynamic Profile of Lenvatinib, an Orally Active, Small-Molecule, Multitargeted Tyrosine Kinase Inhibitor
Ziad Hussein, H. Mizuo, S. Hayato, M. Namiki +1 more
2017European journal of drug metabolism and pharmacokinetics66 citations
Semantic Scholar
Mass screening for hepatocellular carcinoma: Experience in Hokkaido, Japan
S. Mima, C. Sekiya, Hiroshi Kanagawa, H. Kohyama +6 more
1994Journal of Gastroenterology and Hepatology66 citations
Semantic Scholar
Analysis of the full‐length genome of genotype 4 hepatitis E virus isolates from patients with fulminant or acute self‐limited hepatitis E
J. Inoue, T. Nishizawa, Masaharu Takahashi, T. Aikawa +4 more
2006Journal of Medical Virology56 citations
Semantic Scholar
Epidemiological and clinical study of sporadic acute hepatitis E caused by indigenous strains of hepatitis E virus in Japan compared with acute hepatitis A
S. Sainokami, K. Abe, I. Kumagai, A. Miyasaka +9 more
2004Journal of gastroenterology55 citations
Semantic Scholar
[A successfully treated case of fundic varices by retrograde transvenous obliteration with balloon].
Hiroshi Kanagawa, Satoaki Mima, Harukazu Kouyama, H. Mizuo +4 more
1991Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology42 citations
Semantic Scholar
Oxidative Metabolic Pathway of Lenvatinib Mediated by Aldehyde Oxidase
Kazuko Inoue, H. Mizuo, S. Kawaguchi, Katsuyuki Fukuda +2 more
2014Drug Metabolism And Disposition41 citations Open access
Semantic Scholar
Thrombolytic Properties of a Novel Modified Human Tissue‐Type Plasminogen Activator (E6010): A Bolus Injection of E6010 Has Equivalent Potency of Lysing Young and Aged Canine Coronary Thrombi
Suguru Suzuki, M. Saito, N. Suzuki, H. Kato +6 more
1991Journal of Cardiovascular Pharmacology40 citations Open access
Semantic Scholar
Unique Metabolic Pathway of [14C]Lenvatinib after Oral Administration to Male Cynomolgus Monkey
Kazuko Inoue, Naoki Asai, H. Mizuo, Katsuyuki Fukuda +2 more
2012Drug Metabolism And Disposition36 citations
Semantic Scholar
Nucleotide substitutions of hepatitis E virus genomes associated with fulminant hepatitis and disease severity.
J. Inoue, Masaharu Takahashi, H. Mizuo, Kazuyuki Suzuki +3 more
2009Tohoku journal of experimental medicine35 citations Open access
Semantic Scholar
Prevalence and genotype/subtype distribution of hepatitis E virus (HEV) among wild boars in Japan: Identification of a genotype 5 HEV strain.
Masaharu Takahashi, T. Nishizawa, Yukihiro Sato, Shinichi Miyazaki +15 more
2020Virus Research34 citations
Semantic Scholar
Metabolite profiling of the multiple tyrosine kinase inhibitor lenvatinib: a cross-species comparison
A. C. Dubbelman, C. Nijenhuis, R. Jansen, H. Rosing +6 more
2016Investigational new drugs19 citations Open access
Semantic Scholar
Identification of hepatitis E virus in wild sika deer in Japan.
Masaharu Takahashi, A. Nishizono, Manri Kawakami, E. Fukui +7 more
2021Virus Research17 citations
Semantic Scholar
Hepatitis E virus subtype 3f strains isolated from Japanese hepatitis patients with no history of travel to endemic areas - The origin analyzed by molecular evolution.
T. Nakano, Masaharu Takahashi, Kazuaki Takahashi, S. Nagashima +14 more
2018Virology15 citations Open access
Semantic Scholar
Graves' hyperthyroidism following transient thyrotoxicosis during interferon therapy for chronic hepatitis type C.
Shigeki Koizumi, Yasuo Mashio, H. Mizuo, Akira Matsuda +5 more
1995Internal medicine15 citations
Semantic Scholar
Graves' hyperthyroidism showing transient hypothyroidism during interferon therapy for chronic hepatitis type C.
A. Inoue, Shigeki Koizumi, A. Matsuda, H. Mizuo +7 more
2005Endocrine journal9 citations Open access
Semantic Scholar
Minimal impact of hepatic- and renal- impairment on plasma protein binding of lenvatinib, and identification of its major plasma binding protein.
Yuji Mano, H. Mizuo
2019Biopharmaceutics & drug disposition8 citations
Semantic Scholar
Hepatitis E epidemic in Sapporo area by single source strain of HEV genotype 4
Jong-Hon Kang, Takeshi Matsui, A. Saga, J. Akaike +11 more
20108 citations Open access
Semantic Scholar
Bioactivation of diclofenac in human hepatocytes and the proposed human hepatic proteins modified by reactive metabolites
Kazuko Inoue, H. Mizuo, T. Ishida, Takafumi Komori +1 more
2020Xenobiotica; the fate of foreign compounds in biological systems7 citations Open access
Semantic Scholar
Metabolism of an antiallergic agent, azelastine (4-(p-chlorobenzyl)-2-[N-methylperhydroazepinyl-(4)]-1-(2H)-p hthalazin one hydrochloride) in rats and guinea pigs.
K. Tatsumi, Hideyuki Yamada, H. Yoshimura, Y. Nishizawa +3 more
1984Hiroshima journal of medical sciences4 citations
Semantic Scholar
Nationwide Detection and Molecular Characterization of Hepatitis E Virus RNA in Retail Pork Meat in Japan
Masaharu Takahashi, Manri Kawakami, Yukihiro Sato, T. Nakano +16 more
2026Viruses3 citations Open access
Semantic Scholar
[Hepatocellular carcinoma with multiple lung metastasis resulting in long-term disease-free survival by transcatheter arterial infusion chemotherapy of SMANCS].
Junichi Koyama, Shingo Honjo, Ryutaro Morizono, Tetsuhiro Goto +5 more
2011Gan to kagaku ryoho. Cancer & chemotherapy3 citations
Semantic Scholar
A case of lupoid hepatitis observed from acute hepatitis to hepatocellular carcinoma for 7 years
Toshio Tanabe, S. Mima, T. Hanew, H. Mizuo +5 more
19853 citations Open access
Semantic Scholar
Cross-species comparison in nonclinical pharmacokinetics of lenvatinib by a simple HPLC with ultraviolet detection
H. Mizuo, Yuji Mano
2023Scientific Reports2 citations Open access
Semantic Scholar
猪胆（乾燥猪胆囊）からの感染が疑われた急性E型肝炎の1例
Shinichi Miyazaki, Hiroyuki Noda, T. Morita, Y. Kai +6 more
2016Kanzo2 citations Open access
Semantic Scholar
Epidemiological survey of hepatitis E virus infection in Kushiro and Nemuro cities in eastern Hokkaido: relationship between regional difference of HEV prevalence and distinct food cultures
Toshio Tanabe, H. Mizuo, Y. Yazaki, Masaharu Takahashi +1 more
20112 citations Open access
Semantic Scholar
[Five cases of sporadic hepatitis E at Hokkaido Kitami City in Japan].
Hiroshi Yazaki, H. Hirano, Kaoru Tomital, Isao Funakoshil +3 more
2006Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine2 citations Open access
Semantic Scholar
[Gastric cancer in excluded stomach after Roux-en-Y gastric bypass: a case report in Japan].
Junichi Koyama, Atsushi Uesugi, R. Himori, Hideo Takagi +3 more
2022Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology1 citations
Semantic Scholar
[Portal hepatic lymphadenopathy involved by Rosai-Dorfman disease-like changes in a patient with hepatocellular carcinoma].
Hideo Takagi, H. Nishio, Tetsuhiro Goto, K. Morita +6 more
2012Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology1 citations
Semantic Scholar
Studies on the Metabolic Fate of Modified Recombinant Tissue-Type Plasminogen Activator (E6010) (3): Feto-Placental Transfer and Excretion into Milk in Rats after a Single Intravenous Administration of 125I-E6010
H. Mizuo, T. Ando, Y. Kagei, M. Mishima +1 more
19961 citations Open access
Semantic Scholar
Studies on the Metabolic Fate of Modified Recombinant Tissue-Type Plasminogen Activator (E6010) (1): Blood or Plasma Concentration, Distribution, Metabolism and Excretion in Rats after a Single Intravenous Administration of 125I-E-6010 in Comparison with 125I-Recombinant Tissue-Type Plasminogen Acti
H. Mizuo, T. Seko, Koichi Nose, T. Ando +7 more
19961 citations Open access
Semantic Scholar
A CASE OF RUPTURE OF DUODENAL VARICES SUCCESSFULLY TREATED BY ENDOSCOPIC INJECTION SCLEROTHERAPY WITH N-BUTYL-2-CYANOACRYLATE (HISTOACRYL)
M. Hatakeyama, H. Kanagawa, Kenichirou Goto, H. Kohyama +3 more
19941 citations
Semantic Scholar
Synthesis of 14C‐Labelled Cefclidin (E1040)
I. Sugiyama, G. Woolley, H. Mizuo, H. Yamauchi
19921 citations
Semantic Scholar
Studies on the Metabolic Fate of Indometacin Farnesil (IV):Anti-inflamatory Action and Distribution into Inflamed Site in Dogs
M. Mishima, S. Kobayashi, S. Abe, H. Mizuo +3 more
19911 citations Open access
Semantic Scholar
[Preparation of monoclonal antibodies against duck hepatitis B core antigen and analysis of the monoclonal antibodies].
T. Saito, K. Tachibana, K. Mogi, H. Mizuo +2 more
1989Uirusu1 citations
Semantic Scholar
Studies on early detection of hepatocellular carcinoma - Mass survey by real-time ultrasound and serum battery tests.
S. Mima, M. Fukuda, H. Itaya, K. Hirata +11 more
19851 citations Open access
Semantic Scholar
CARRIER-MEDIATED TRANSPORT MECHANISM IN THE RAT INTESTINAL ABSORPTION OF AMINO-β-LACTAM ANTIBIOTICS
E. Nakashima, H. Mizuo, A. Tsuji, T. Yamana
19831 citations
Semantic Scholar

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