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K. Riching · SciRah

Researcher profile · Semantic Scholar

K. Riching

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K. Riching — researcher profile on SciRah

h-index: 22
Works: 47
Citations: 4,888

Most-cited papers

Aligned collagen is a prognostic signature for survival in human breast carcinoma.
M. Conklin, J. Eickhoff, K. Riching, C. Pehlke +4 more
2011American Journal of Pathology1,229 citations Open access
Semantic Scholar
In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia
M. Skala, K. Riching, A. Gendron‐Fitzpatrick, J. Eickhoff +3 more
2007Proceedings of the National Academy of Sciences of the United States of America1,099 citations Open access
Semantic Scholar
3D collagen alignment limits protrusions to enhance breast cancer cell persistence.
K. Riching, B. Cox, M. Salick, C. Pehlke +8 more
2014Biophysical Journal409 citations Open access
Semantic Scholar
In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia.
M. Skala, K. Riching, D. Bird, A. Gendron‐Fitzpatrick +4 more
2007Journal of Biomedical Optics402 citations Open access
Semantic Scholar
Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7
Vittoria Zoppi, S. Hughes, Chiara Maniaci, A. Testa +7 more
2018Journal of Medicinal Chemistry268 citations Open access
Semantic Scholar
Quantitative Live-Cell Kinetic Degradation and Mechanistic Profiling of PROTAC Mode of Action.
K. Riching, Sarah D. Mahan, Cesear R. Corona, Mark G. Mcdougall +4 more
2018ACS Chemical Biology259 citations Open access
Semantic Scholar
Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity
Satomi Imaide, K. Riching, N. Makukhin, Vesna Vetma +13 more
2021Nature Chemical Biology194 citations Open access
Semantic Scholar
Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension.
Scott Gehler, M. Baldassarre, Yatish Lad, J. Leight +6 more
2009Molecular Biology of the Cell127 citations Open access
Semantic Scholar
Discovery and Resistance Mechanism of a Selective CDK12 Degrader
Bai-Shan Jiang, Yang Gao, Jian-Wei Che, Wenchao Lu +13 more
2021Nature Chemical Biology116 citations Open access
Semantic Scholar
SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer
Hai-Li Ma, M. Bizet, Christelle Soares Da Costa, Frédéric Murisier +26 more
2023Molecules and Cells83 citations Open access
Semantic Scholar
A Three-Dimensional Computational Model of Collagen Network Mechanics
Byoungkoo Lee, Xin Zhou, K. Riching, K. Eliceiri +4 more
2014PLoS ONE78 citations Open access
Semantic Scholar
Bi-directional signaling: Extracellular Matrix and Integrin Regulation of Breast Tumor Progression
Scott Gehler, S. Ponik, K. Riching, P. Keely
2013Critical Reviews in Eukaryotic Gene Expression61 citations Open access
Semantic Scholar
Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs
Nan Bai, K. Riching, Aman Makaju, Hao Wu +11 more
2022Journal of Biological Chemistry54 citations Open access
Semantic Scholar
Monitoring and deciphering protein degradation pathways inside cells.
D. Daniels, K. Riching, M. Urh
2019Drug Discovery Today : Technologies54 citations Open access
Semantic Scholar
The importance of cellular degradation kinetics for understanding mechanisms in targeted protein degradation.
K. Riching, Elizabeth A. Caine, M. Urh, D. Daniels
2022Chemical Society Reviews53 citations Open access
Semantic Scholar
Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines
Gisele Nishiguchi, Lauren G. Mascibroda, Sarah M Young, Elizabeth A. Caine +31 more
2024Nature Communications50 citations Open access
Semantic Scholar
Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexes
L. Kilpatrick, R. Friedman-Ohana, Diana C. Alcobia, K. Riching +9 more
2017Biochemical Pharmacology50 citations Open access
Semantic Scholar
Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation
Giuseppe Quarto, Andrea Li Greci, M. Bizet, Audrey Penning +37 more
2025Cell45 citations Open access
Semantic Scholar
CDK Family PROTAC Profiling Reveals Distinct Kinetic Responses and Cell Cycle–Dependent Degradation of CDK2
K. Riching, Marie K. Schwinn, J. Vasta, M. Robers +3 more
2020SLAS discovery : advancing life sciences R & D40 citations Open access
Semantic Scholar
R-Ras regulates β1-integrin trafficking via effects on membrane ruffling and endocytosis
M. Conklin, Aude Ada-Nguema, M. Parsons, K. Riching +1 more
2010BMC Cell Biology38 citations Open access
Semantic Scholar
Targeted Protein Degradation Phenotypic Studies Using HaloTag CRISPR/Cas9 Endogenous Tagging Coupled with HaloPROTAC3
Elizabeth A. Caine, Sarah D. Mahan, Rebecca L. Johnson, A. Nieman +5 more
2020Current Protocols in Pharmacology32 citations Open access
Semantic Scholar
High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds using HiBiT CRISPR Cell Lines.
K. Riching, Sarah D. Mahan, M. Urh, D. Daniels
2020Journal of Visualized Experiments27 citations Open access
Semantic Scholar
Rho family GTPases: making it to the third dimension
K. Riching, P. Keely
2014International Journal of Biochemistry and Cell Biology21 citations Open access
Semantic Scholar
Translating PROTAC chemical series optimization into functional outcomes underlying BRD7 and BRD9 protein degradation
K. Riching, J. Vasta, S. Hughes, Vittoria Zoppi +5 more
2021Current Research in Chemical Biology20 citations Open access
Semantic Scholar
Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo.
B. Burkel, B. Morris, S. Ponik, K. Riching +2 more
2016Journal of Visualized Experiments17 citations Open access
Semantic Scholar
Structure–Activity Relationship of Potent, Selective, and Orally Bioavailable Molecular Glue Degraders of CK1α
Gisele Nishiguchi, Elizabeth A. Caine, Kevin McGowan, Zhe Shi +13 more
2024ACS Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Longitudinal Label-free Tracking of Cell Death Dynamics in Living Engineered Human Skin Tissue with a Multimodal Microscope References and Links
You-Bo Zhao, M. Marjanovic, E. Chaney, B. W. Graf +190 more
11 citations
Semantic Scholar
In vivo Multiphoton Fluorescence Lifetime Imaging of Free and Protein-Bound NADH in Normal and Pre-Cancerous Epithelia
M. Skala, K. Riching, D. K. Bird, Kristin M. Vrotsos +3 more
200610 citations
Semantic Scholar
Multiphoton lifetime imaging of endogenous fluorescence in normal and precancererous epithelial tissues in vivo
M. Skala, D. Bird, K. Riching, Kristin M. Vrotsos +3 more
200510 citations
Semantic Scholar
Kinetic Detection of E3:PROTAC:Target Ternary Complexes Using NanoBRET Technology in Live Cells.
Sarah D. Mahan, K. Riching, M. Urh, D. Daniels
2021Methods in molecular biology9 citations
Semantic Scholar
Development of an intracellular quantitative assay to measure compound binding kinetics.
Charles S. Lay, Daniel A. Thomas, John P. Evans, M. Campbell +10 more
2021Cell Chemical Biology5 citations Open access
Semantic Scholar
Trivalent PROTACs enhance protein degradation through cooperativity and avidity
Satomi Imaide, K. Riching, Vesna Vetma, Claire Whitworth +10 more
20205 citations Open access
Semantic Scholar
Monitoring PROTAC interactions in biochemical assays using Lumit immunoassays.
Ellen Crummy, Elizabeth A. Caine, D. Mikheil, Cesear R. Corona +3 more
2023Methods in Enzymology4 citations
Semantic Scholar
Abstract A35: Aligned collagen is a prognostic signature for survival in human breast carcinoma
M. Conklin, J. Eickhoff, K. Riching, C. Pehlke +4 more
20113 citations
Semantic Scholar
Matrix Pathobiology Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma
M. Conklin, J. Eickhoff, K. Riching, C. Pehlke +4 more
20111 citations
Semantic Scholar
Abstract 5230: Real-time monitoring of PROTAC and molecular glue targeted degradation in living cells
N. Cosby, K. Riching, Sarah D. Mahan, Elizabeth A. Caine +2 more
2020Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 6409: Targeted degradation of endogenously tagged proteins for phenotypic studies using HaloPROTAC3 and HaloTag technologies
Elizabeth A. Caine, Sarah D. Mahan, K. Riching, Nancy Murphy +5 more
2020Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Trivalent PROTACs enhance protein degradation through cooperativity and avidity
A. Ciulli, K. Riching
20200 citations
Semantic Scholar
Illuminating Protein:Protein Interactions in Living Cells
D. Daniels, T. Machleidt, Jacqui Méndez, K. Riching +5 more
20150 citations
Semantic Scholar
Parameters for elastic collagen fiber network simulations.
Byoungkoo Lee, Xin Zhou, K. Riching, K. Eliceiri +4 more
20140 citations Open access
Semantic Scholar
Condensed Title: FLNa-β1 tunes response to matrix tension
Scott Gehler, M. Baldassarre, Yatish Lad, J. Leight +4 more
20130 citations
Semantic Scholar
The Sobering Effect of Matrix Alignment on Breast Cancer Cell Migration
K. Riching
20130 citations
Semantic Scholar
AMERICAN SOCIETY FOR LASER MEDICINE AND SURGERY TWENTY-SIXTH ANNUAL MEETING BOSTON, MASSACHUSETTS APRIL 5–APRIL 9, 2006 ABSTRACTS BASIC SCIENCE: THE CUTTING EDGE IN OPTICAL DIAGNOSTICS AND THERAPEUTICS OF TISSUES AND CELLS
Katherine Roldan-Perez, K. Riching, G. Palmer, N. Ramanujam +11 more
20060 citations
Semantic Scholar
Results of the 2005-2006 RERC on AMI senior design competition
Kevin E. Villani, Sally Jensen, K. Riching, A. Harris +4 more
2006IEEE Engineering in Medicine and Biology Magazine0 citations
Semantic Scholar
Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma Address Reprint Requests to See Related Commentary on Page 966
M. Conklin, Jens C. Eickhoff, K. Riching, C. Pehlke +8 more
0 citations
Semantic Scholar
Optical Metabolic Imaging Quantifies Heterogeneous Cell Populations References and Links
Alex J. Walsh, M. Skala, L. Fisher, C. Pusztai +64 more
0 citations
Semantic Scholar

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P. Keely×15
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C. Pehlke — researcher profile on SciRah

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