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K. Leroy · SciRah

Researcher profile · Semantic Scholar

K. Leroy

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K. Leroy — researcher profile on SciRah

h-index: 48
Works: 162
Citations: 8,937

Most-cited papers

TP53, STK11, and EGFR Mutations Predict Tumor Immune Profile and the Response to Anti–PD-1 in Lung Adenocarcinoma
J. Biton, A. Mansuet-Lupo, N. Pécuchet, M. Alifano +14 more
2018Clinical Cancer Research309 citations
Semantic Scholar
MYC-IG rearrangements are negative predictors of survival in DLBCL patients treated with immunochemotherapy: a GELA/LYSA study.
C. Copie-Bergman, P. Cuillière-Dartigues, M. Baia, J. Briére +19 more
2015Blood243 citations
Semantic Scholar
Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease.
J. Emile, E. Diamond, Z. Hélias-Rodzewicz, F. Cohen-Aubart +19 more
2014Blood238 citations Open access
Semantic Scholar
Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma
J. Gunawardana, F. Chan, A. Telenius, B. Woolcock +18 more
2014Nature Genetics199 citations
Semantic Scholar
Next-Generation Sequencing in Diffuse Large B-Cell Lymphoma Highlights Molecular Divergence and Therapeutic Opportunities: a LYSA Study
S. Dubois, P. Viailly, S. Mareschal, E. Bohers +26 more
2016Clinical Cancer Research193 citations Open access
Semantic Scholar
Accurate Classification of Germinal Center B-Cell-Like/Activated B-Cell-Like Diffuse Large B-Cell Lymphoma Using a Simple and Rapid Reverse Transcriptase-Multiplex Ligation-Dependent Probe Amplification Assay: A CALYM Study.
S. Mareschal, P. Ruminy, C. Bagacean, V. Marchand +11 more
2015Journal of Molecular Diagnostics171 citations Open access
Semantic Scholar
Dimethyl fumarate, a two‐edged drug: Current status and future directions
N. E. B. Saidu, N. Kavian, K. Leroy, C. Jacob +3 more
2019Medicinal research reviews (Print)150 citations
Semantic Scholar
The tumor inflammation signature (TIS) is associated with anti-PD-1 treatment benefit in the CERTIM pan-cancer cohort
D. Damotte, S. Warren, J. Arrondeau, P. Boudou-Rouquette +20 more
2019Journal of Translational Medicine127 citations Open access
Semantic Scholar
Efficacy of Immune Checkpoint Inhibitors in Lung Sarcomatoid Carcinoma.
C. Domblides, K. Leroy, I. Monnet, J. Mazières +19 more
2020Journal of Thoracic Oncology124 citations Open access
Semantic Scholar
DNA degrades during storage in formalin-fixed and paraffin-embedded tissue blocks
A. Guyard, Alice Boyez, A. Pujals, C. Robe +7 more
2017Virchows Archiv117 citations
Semantic Scholar
Biological and Clinical Relevance of Associated Genomic Alterations in MYD88 L265P and non-L265P–Mutated Diffuse Large B-Cell Lymphoma: Analysis of 361 Cases
S. Dubois, P. Viailly, E. Bohers, P. Bertrand +25 more
2016Clinical Cancer Research106 citations Open access
Semantic Scholar
Predictive Value of Soluble PD-1, PD-L1, VEGFA, CD40 Ligand and CD44 for Nivolumab Therapy in Advanced Non-Small Cell Lung Cancer: A Case-Control Study
M. Tiako-Meyo, A. Jouinot, E. Giroux-Leprieur, E. Fabre +15 more
2020Cancers102 citations Open access
Semantic Scholar
Recurrent mutations of the exportin 1 gene (XPO1) and their impact on selective inhibitor of nuclear export compounds sensitivity in primary mediastinal B‐cell lymphoma
F. Jardin, A. Pujals, L. Pelletier, E. Bohers +33 more
2016American journal of hematology/oncology100 citations Open access
Semantic Scholar
Hsa-miR-31-3p Expression Is Linked to Progression-free Survival in Patients with KRAS Wild-type Metastatic Colorectal Cancer Treated with Anti-EGFR Therapy
G. Manceau, S. Imbeaud, Raphaële Thiébaut, F. Liébaert +25 more
2014Clinical Cancer Research98 citations Open access
Semantic Scholar
Whole exome sequencing of relapsed/refractory patients expands the repertoire of somatic mutations in diffuse large B‐cell lymphoma
S. Mareschal, S. Dubois, P. Viailly, P. Bertrand +15 more
2016Genes, Chromosomes and Cancer96 citations
Semantic Scholar
Sarcopenic overweight is associated with early acute limiting toxicity of anti-PD1 checkpoint inhibitors in melanoma patients
V. Heidelberger, F. Goldwasser, N. Kramkimel, A. Jouinot +11 more
2017Investigational new drugs87 citations
Semantic Scholar
Somatic mutations of cell-free circulating DNA detected by next-generation sequencing reflect the genetic changes in both germinal center B-cell-like and activated B-cell-like diffuse large B-cell lymphomas at the time of diagnosis
E. Bohers, P. Viailly, S. Dubois, P. Bertrand +10 more
2015Haematologica73 citations Open access
Semantic Scholar
Dimethyl Fumarate Controls the NRF2/DJ-1 Axis in Cancer Cells: Therapeutic Applications
N. E. B. Saidu, G. Noé, O. Cerles, L. Cabel +10 more
2016Molecular Cancer Therapeutics71 citations Open access
Semantic Scholar
Tumor heterogeneity of fibroblast growth factor receptor 3 (FGFR3) mutations in invasive bladder cancer: implications for perioperative anti-FGFR3 treatment.
D. Pouessel, Y. Neuzillet, L. Mertens, M. S. van der Heijden +35 more
2016Annals of Oncology63 citations Open access
Semantic Scholar
Neoadjuvant FOLFOX 4 versus FOLFOX 4 with Cetuximab versus immediate surgery for high-risk stage II and III colon cancers: a multicentre randomised controlled phase II trial – the PRODIGE 22 - ECKINOXE trial
M. Karoui, A. Rullier, A. Luciani, F. Bonnetain +12 more
2015BMC Cancer54 citations Open access
Semantic Scholar
The alternative RelB NF-κB subunit is a novel critical player in diffuse large B-cell lymphoma.
B. Eluard, Stéphanie Nuan-Aliman, N. Faumont, D. Collares +23 more
2021Blood53 citations
Semantic Scholar
MicroRNAome profiling in benign and malignant neurofibromatosis type 1-associated nerve sheath tumors: evidences of PTEN pathway alterations in early NF1 tumorigenesis
J. Masliah-Planchon, É. Pasmant, A. Luscan, I. Laurendeau +12 more
2013BMC Genomics53 citations Open access
Semantic Scholar
Somatic IL4R mutations in primary mediastinal large B-cell lymphoma lead to constitutive JAK-STAT signaling activation.
E. Viganò, J. Gunawardana, A. Mottok, Tessa Van Tol +21 more
2018Blood52 citations Open access
Semantic Scholar
The strategic roles of four enzymes in the interconnection between metabolism and oncogene activation in non-small cell lung cancer: Therapeutic implications.
P. Icard, Luca Simula, L. Fournel, K. Leroy +11 more
2022Drug resistance updates51 citations Open access
Semantic Scholar
Determination of Molecular Subtypes of Diffuse Large B-Cell Lymphoma Using a Reverse Transcriptase Multiplex Ligation-Dependent Probe Amplification Classifier: A CALYM Study.
Victor Bobée, P. Ruminy, V. Marchand, P. Viailly +16 more
2017Journal of Molecular Diagnostics49 citations Open access
Semantic Scholar
Redifferentiating Effect of Larotrectinib in NTRK-Rearranged Advanced Radioactive-Iodine Refractory Thyroid Cancer
L. Groussin, H. Théodon, Laura Bessiene, L. Bricaire +11 more
2022Thyroid48 citations
Semantic Scholar
SMARCA4-deficient lung carcinoma is an aggressive tumor highly infiltrated by FOXP3+ cells and neutrophils.
Y. Velut, E. Decroix, H. Blons, M. Alifano +13 more
2022Lung Cancer48 citations Open access
Semantic Scholar
Cracking the homologous recombination deficiency code: how to identify responders to PARP inhibitors.
Lola Paulet, A. Trécourt, A. Leary, J. Péron +5 more
2022European Journal of Cancer45 citations Open access
Semantic Scholar
Refining diffuse large B-cell lymphoma subgroups using integrated analysis of molecular profiles
S. Dubois, B. Tesson, S. Mareschal, P. Viailly +14 more
2019EBioMedicine44 citations Open access
Semantic Scholar
Immunoglobulin heavy chain/light chain pair measurement is associated with survival in diffuse large B-cell lymphoma
F. Jardin, M. Delfau-Larue, T. Molina, C. Copie-Bergman +17 more
2013Leukemia and Lymphoma43 citations
Semantic Scholar
Dimethyl fumarate is highly cytotoxic in KRAS mutated cancer cells but spares non-tumorigenic cells
Nathaniel Edward Bennett Saidu, M. Bretagne, Audrey Lupo Mansuet, P. Just +10 more
2018OncoTarget37 citations Open access
Semantic Scholar
STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL)
O. Ritz, Karolin Rommel, K. Dorsch, Elena Kelsch +9 more
2013OncoTarget36 citations Open access
Semantic Scholar
Three Rounds of External Quality Assessment in France to Evaluate the Performance of 28 Platforms for Multiparametric Molecular Testing in Metastatic Colorectal and Non-Small Cell Lung Cancer.
E. Dequeker, Cleo Keppens, C. Égelé, Sofie Delen +30 more
2016Journal of Molecular Diagnostics28 citations Open access
Semantic Scholar
BRAF V600E mutations in bile duct adenomas
A. Pujals, G. Amaddeo, C. Castain, P. Bioulac-Sage +6 more
2015Hepatology28 citations Open access
Semantic Scholar
Rituximab, alkylating agents or combination therapy for gastric mucosa‐associated lymphoid tissue lymphoma: a monocentric non‐randomised observational study
A. Amiot, Michaël Lévy, C. Copie-Bergman, J. Dupuis +8 more
2014Alimentary Pharmacology and Therapeutics26 citations Open access
Semantic Scholar
Performance and Cost Efficiency of KRAS Mutation Testing for Metastatic Colorectal Cancer in Routine Diagnosis: The MOKAECM Study, a Nationwide Experience
H. Blons, E. Rouleau, N. Charrier, G. Chatellier +20 more
2013PLoS ONE25 citations Open access
Semantic Scholar
Erratum to: Sarcopenic overweight is associated with early acute limiting toxicity of anti-PD1 checkpoint inhibitors in melanoma patients
V. Heidelberger, F. Goldwasser, N. Kramkimel, A. Jouinot +11 more
2017Investigational new drugs24 citations Open access
Semantic Scholar
Reliable subtype classification of diffuse large B-cell lymphoma samples from GELA LNH2003 trials using the Lymph2Cx gene expression assay
J. Jais, T. Molina, P. Ruminy, D. Gentien +12 more
2017Haematologica23 citations Open access
Semantic Scholar
Chemoresistant pleomorphic rhabdomyosarcoma: whole exome sequencing reveals underlying cancer predisposition and therapeutic options
C. Tlemsani, K. Leroy, A. Gimenez-Roqueplo, A. Mansuet-Lupo +8 more
2018Journal of Medical Genetics21 citations
Semantic Scholar
Zinc Gluconate Induces Potentially Cancer Chemopreventive Activity in Barrett’s Esophagus: A Phase 1 Pilot Study
M. Valenzano, E. Rybakovsky, V. Chen, K. Leroy +23 more
2020Digestive Diseases and Sciences20 citations Open access
Semantic Scholar
Identification of TP53 mutated group using a molecular and immunohistochemical classification of endometrial carcinoma to improve prognostic evaluation for adjuvant treatments
Guillaume Beinse, B. Rance, P. Just, B. Izac +12 more
2020International Journal of Gynecological Cancer19 citations Open access
Semantic Scholar
STAT6 is a cargo of exportin 1: Biological relevance in primary mediastinal B-cell lymphoma.
Hadjer Miloudi, K. Leroy, F. Jardin, B. Sola
2018Cellular Signalling19 citations Open access
Semantic Scholar
EGFR Exon 20 Insertion in Metastatic Non-Small-Cell Lung Cancer: Survival and Clinical Efficacy of EGFR Tyrosine-Kinase Inhibitor and Chemotherapy
S. Chelabi, X. Mignard, K. Leroy, I. Monnet +9 more
2021Cancers18 citations Open access
Semantic Scholar
c-Rel Is the Pivotal NF-κB Subunit in Germinal Center Diffuse Large B-Cell Lymphoma: A LYSA Study
N. Faumont, O. Taoui, D. Collares, J. Jais +11 more
2021Frontiers in Oncology17 citations Open access
Semantic Scholar
NF1 mutations identify molecular and clinical subtypes of lung adenocarcinomas
C. Tlemsani, N. Pécuchet, Aurélia Gruber, I. Laurendeau +19 more
2019Cancer Medicine17 citations Open access
Semantic Scholar
Standardisation of pathogenicity classification for somatic alterations in solid tumours and haematologic malignancies.
Florence Koeppel, Etienne Muller, Alexandre Harlé, C. Guien +16 more
2021European Journal of Cancer15 citations Open access
Semantic Scholar
The NRF2 transcriptional target NQO1 has low mRNA levels in TP53-mutated endometrial carcinomas
Guillaume Beinse, P. Just, B. Rance, B. Izac +10 more
2019PLoS ONE15 citations Open access
Semantic Scholar
No evidence for a pathogen associated with pulmonary MALT lymphoma: a metagenomics investigation
R. Borie, V. Caro, H. Nunes, M. Kambouchner +10 more
2020Infectious Agents and Cancer14 citations Open access
Semantic Scholar
Discovery and validation of a transcriptional signature identifying homologous recombination-deficient breast, endometrial and ovarian cancers
Guillaume Beinse, P. Just, M. le Frère Belda, P. Laurent-Puig +16 more
2022British Journal of Cancer11 citations Open access
Semantic Scholar
Transcriptome in paraffin samples for the diagnosis and prognosis of adrenocortical carcinoma
A. Jouinot, Juliane Lippert, M. Sibony, Florian Violon +20 more
2022European Journal of Endocrinology10 citations Open access
Semantic Scholar

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