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A. Methner · SciRah

Researcher profile · Semantic Scholar

A. Methner

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A. Methner — researcher profile on SciRah

h-index: 43
Works: 114
Citations: 6,154

Most-cited papers

The Cystine/Glutamate Antiporter System xc − in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities
J. Lewerenz, S. Hewett, Ying Huang, M. Lambros +9 more
2013Antioxidants and Redox Signaling946 citations Open access
Semantic Scholar
Oxytosis/Ferroptosis—(Re-) Emerging Roles for Oxidative Stress-Dependent Non-apoptotic Cell Death in Diseases of the Central Nervous System
J. Lewerenz, G. Ates, A. Methner, M. Conrad +1 more
2018Frontiers in Neuroscience248 citations Open access
Semantic Scholar
Crucial role for Nox2 and sleep deprivation in aircraft noise-induced vascular and cerebral oxidative stress, inflammation, and gene regulation
Swenja Kröller-Schön, A. Daiber, S. Steven, M. Oelze +20 more
2018European Heart Journal217 citations Open access
Semantic Scholar
Effects of dimethyl fumarate on neuroprotection and immunomodulation
P. Albrecht, Imane Bouchachia, N. Goebels, N. Henke +11 more
2012Journal of Neuroinflammation212 citations Open access
Semantic Scholar
Optical Coherence Tomography in Parkinsonian Syndromes
P. Albrecht, A. Müller, M. Südmeyer, S. Ferrea +9 more
2012PLoS ONE188 citations Open access
Semantic Scholar
The role of Ca2+ in cell death caused by oxidative glutamate toxicity and ferroptosis
P. Maher, K. van Leyen, P. Dey, B. Honrath +2 more
2017Cell Calcium185 citations Open access
Semantic Scholar
Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases
N. M. Connolly, Pierre Theurey, V. Ádám-Vizi, N. Bazan +42 more
2017Cell Death and Differentiation180 citations Open access
Semantic Scholar
Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro
J. Lewerenz, P. Albrecht, Mai-Ly Tran Tien, N. Henke +6 more
2009Journal of Neurochemistry180 citations
Semantic Scholar
Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc- as a neuroprotective drug target.
P. Albrecht, J. Lewerenz, Sonja Dittmer, R. Noack +2 more
2010CNS and Neurological Disorders - Drug Targets176 citations
Semantic Scholar
Cooperative action of glutamate transporters and cystine/glutamate antiporter system Xc– protects from oxidative glutamate toxicity
J. Lewerenz, M. Klein, A. Methner
2006Journal of Neurochemistry164 citations
Semantic Scholar
Degeneration of retinal layers in multiple sclerosis subtypes quantified by optical coherence tomography
P. Albrecht, M. Ringelstein, AK Müller, N. Keser +6 more
2012Multiple Sclerosis127 citations
Semantic Scholar
Metformin reverses early cortical network dysfunction and behavior changes in Huntington’s disease
I. Arnoux, M. Willam, N. Griesche, J. Krummeich +17 more
2018eLife101 citations Open access
Semantic Scholar
The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress
N. Henke, P. Albrecht, I. Bouchachia, M. Ryazantseva +5 more
2013Cell Death and Disease100 citations Open access
Semantic Scholar
The C Terminus of Bax Inhibitor-1 Forms a Ca2+-permeable Channel Pore*
G. Bultynck, S. Kiviluoto, N. Henke, Hristina Ivanova +10 more
2011Journal of Biological Chemistry98 citations Open access
Semantic Scholar
The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state.
D. Lisak, T. Schacht, Vitalij Enders, J. Habicht +5 more
2015Biochimica et Biophysica Acta93 citations Open access
Semantic Scholar
Charcot-Marie-Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential.
R. Noack, S. Frede, P. Albrecht, N. Henke +13 more
2012Human Molecular Genetics88 citations
Semantic Scholar
Store-operated calcium entry modulates neuronal network activity in a model of chronic epilepsy.
Julius A. Steinbeck, N. Henke, J. Opatz, J. Gruszczynska-Biegala +8 more
2011Experimental Neurology87 citations
Semantic Scholar
Regulation of xCT expression and system $$ x_{\text{c}}^{ - } $$ function in neuronal cells
J. Lewerenz, P. Maher, A. Methner
2011Amino Acids85 citations
Semantic Scholar
TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex
Sonja Dittmer, Z. Kovacs, Shauna H. Yuan, Gabriella Siszler +6 more
2011Journal of Cell Science85 citations
Semantic Scholar
Immunolocalization of STIM1 in the mouse brain.
A. Skibinska-Kijek, M. Wiśniewska, J. Gruszczynska-Biegala, A. Methner +1 more
2009Acta Neurobiologiae Experimentalis85 citations Open access
Semantic Scholar
The ancient cell death suppressor BAX inhibitor-1.
N. Henke, D. Lisak, L. Schneider, J. Habicht +2 more
2011Cell Calcium80 citations
Semantic Scholar
The Constitutively Active Orphan G-protein-coupled Receptor GPR39 Protects from Cell Death by Increasing Secretion of Pigment Epithelium-derived Growth Factor*
Sonja Dittmer, Mert Şahin, A. Pantlen, A. Saxena +5 more
2008Journal of Biological Chemistry77 citations Open access
Semantic Scholar
Optical coherence tomography measures axonal loss in multiple sclerosis independently of optic neuritis
P. Albrecht, R. Fröhlich, Hans-Peter Hartung, B. Kieseier +1 more
2007Journal of Neurology76 citations
Semantic Scholar
Subtle retinal pathology in amyotrophic lateral sclerosis
M. Ringelstein, P. Albrecht, M. Südmeyer, Jens Harmel +9 more
2014Annals of Clinical and Translational Neurology75 citations Open access
Semantic Scholar
Mutation of ATF4 mediates resistance of neuronal cell lines against oxidative stress by inducing xCT expression
Jan Lewerenz, Hideyo Sato, Philipp Albrecht, N. Henke +3 more
2011Cell Death and Differentiation74 citations Open access
Semantic Scholar
Phosphoinositide 3-Kinases Upregulate System xc − via Eukaryotic Initiation Factor 2α and Activating Transcription Factor 4 – A Pathway Active in Glioblastomas and Epilepsy
J. Lewerenz, P. Baxter, R. Kassubek, P. Albrecht +14 more
2014Antioxidants and Redox Signaling65 citations Open access
Semantic Scholar
Optical coherence tomography for the diagnosis and monitoring of idiopathic intracranial hypertension
P. Albrecht, Christine Blasberg, M. Ringelstein, A. Müller +9 more
2017Journal of Neurology64 citations
Semantic Scholar
Stromal Interaction Molecule 1 (STIM1) Is Involved in the Regulation of Mitochondrial Shape and Bioenergetics and Plays a Role in Oxidative Stress*
N. Henke, P. Albrecht, Annika Pfeiffer, Diamandis Toutzaris +2 more
2012Journal of Biological Chemistry62 citations Open access
Semantic Scholar
Mitochondrial function and energy metabolism in neuronal HT22 cells resistant to oxidative stress
Annika Pfeiffer, M. Jaeckel, J. Lewerenz, R. Noack +7 more
2014British Journal of Pharmacology54 citations Open access
Semantic Scholar
Neuromyelitis optica following human papillomavirus vaccination
T. Menge, B. Cree, A. Saleh, T. Waterboer +7 more
2012Neurology54 citations
Semantic Scholar
Bax Inhibitor-1 is a novel IP3 receptor-interacting and -sensitizing protein
S. Kiviluoto, L. Schneider, T. Luyten, T. Vervliet +5 more
2012Cell Death and Disease50 citations Open access
Semantic Scholar
Retinal Neurodegeneration in Wilson’s Disease Revealed by Spectral Domain Optical Coherence Tomography
P. Albrecht, A. Müller, M. Ringelstein, D. Finis +6 more
2012PLoS ONE50 citations Open access
Semantic Scholar
Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease
M. Czeredys, J. Gruszczynska-Biegala, T. Schacht, A. Methner +1 more
2013Frontiers in Molecular Neuroscience49 citations Open access
Semantic Scholar
Abnormalities of synaptic mitochondria in autism spectrum disorder and related neurodevelopmental disorders
Liliana Rojas-Charry, L. Nardi, A. Methner, M. J. Schmeisser
2020Journal of molecular medicine45 citations Open access
Semantic Scholar
Regulators of mitochondrial Ca2+ homeostasis in cerebral ischemia
Michael K. E. Schäfer, Annika Pfeiffer, M. Jaeckel, A. Pouya +2 more
2014Cell and Tissue Research45 citations
Semantic Scholar
Dimethyl fumarate treatment after traumatic brain injury prevents depletion of antioxidative brain glutathione and confers neuroprotection
Tobias J. Krämer, T. Grob, Lutz Menzel, Tobias Hirnet +5 more
2017Journal of Neurochemistry44 citations
Semantic Scholar
Bax Inhibitor-1 Is Likely a pH-Sensitive Calcium Leak Channel, Not a H+/Ca2+ Exchanger
G. Bultynck, S. Kiviluoto, A. Methner
2014Science Signaling44 citations
Semantic Scholar
The thiol switch C684 in Mitofusin‐2 mediates redox‐induced alterations of mitochondrial shape and respiration
Osamah Thaher, Christina Wolf, P. Dey, A. Pouya +3 more
2017Neurochemistry International39 citations
Semantic Scholar
Interaction of Bcl-2 with the Autophagy-related GABAA Receptor-associated Protein (GABARAP)
Peixiang Ma, M. Schwarten, L. Schneider, Alexandra Boeske +10 more
2013Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase
C. Hoffmann, M. Dietrich, Ann-Kathrin Herrmann, T. Schacht +2 more
2017Oxidative Medicine and Cellular Longevity36 citations Open access
Semantic Scholar
BAX inhibitor-1 is a Ca2+ channel critically important for immune cell function and survival
D. Lisak, T. Schacht, A. Gawlitza, P. Albrecht +15 more
2015Cell Death and Differentiation35 citations Open access
Semantic Scholar
Redox Modifications of Proteins of the Mitochondrial Fusion and Fission Machinery
Christina Wolf, Víctor López del Amo, S. Arndt, Diones Bueno +4 more
2020Cells34 citations Open access
Semantic Scholar
Absence of system xc− on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis
Ellen Merckx, G. Albertini, M. Paterka, C. Jensen +14 more
2017Journal of Neuroinflammation34 citations Open access
Semantic Scholar
Mitochondrial respiratory states and rates
E. Gnaiger, E. A. Frostner, N. A. Karim, N. Abumrad +496 more
201933 citations Open access
Semantic Scholar
Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis.
S. Kiviluoto, T. Luyten, L. Schneider, D. Lisak +8 more
2013Cell Calcium30 citations Open access
Semantic Scholar
Extracellular cyclic GMP and its derivatives GMP and guanosine protect from oxidative glutamate toxicity.
P. Albrecht, N. Henke, Mai-Ly Tran Tien, Andrea Issberner +4 more
2013Neurochemistry International30 citations
Semantic Scholar
TMBIM5 loss of function alters mitochondrial matrix ion homeostasis and causes a skeletal myopathy
Li Zhang, Felicia Dietsche, Bruno Seitaj, Liliana Rojas-Charry +17 more
2022Life Science Alliance29 citations Open access
Semantic Scholar
Tetrahydrocarbazoles decrease elevated SOCE in medium spiny neurons from transgenic YAC128 mice, a model of Huntington's disease.
M. Czeredys, F. Maciąg, A. Methner, J. Kuźnicki
2017Biochemical and Biophysical Research Communications - BBRC28 citations Open access
Semantic Scholar
Induction of Bcl-2 by functional regulation of G-protein coupled receptors protects from oxidative glutamate toxicity by increasing glutathione
Mert Şahin, A. Saxena, P. Joost, J. Lewerenz +1 more
2006Free radical research28 citations
Semantic Scholar
Retinal pathology in idiopathic moyamoya angiopathy detected by optical coherence tomography
P. Albrecht, Christine Blasberg, S. Lukas, M. Ringelstein +12 more
2015Neurology27 citations
Semantic Scholar

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S. Kiviluoto — researcher profile on SciRah