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Darren M. Gordon · SciRah

Researcher profile · Semantic Scholar

Darren M. Gordon

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Darren M. Gordon — researcher profile on SciRah

h-index: 12
Works: 17
Citations: 820

Most-cited papers

Bilirubin as a Metabolic Hormone: The Physiological Relevance of Low Levels.
J. Creeden, Darren M. Gordon, D. Stec, T. Hinds
2020American Journal of Physiology. Endocrinology and Metabolism213 citations Open access
Semantic Scholar
The loss of hepatic PPARα promotes inflammation and serum hyperlipidemia in diet-induced obesity.
D. Stec, Darren M. Gordon, Jennifer A. Hipp, Stephen H Hong +6 more
2019American Journal of Physiology. Regulatory Integrative and Comparative Physiology93 citations Open access
Semantic Scholar
Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator–activated receptor α
Darren M. Gordon, Kari L. Neifer, A. Hamoud, Charles F. Hawk +9 more
2020Journal of Biological Chemistry91 citations Open access
Semantic Scholar
Bilirubin Nanoparticles Reduce Diet-Induced Hepatic Steatosis, Improve Fat Utilization, and Increase Plasma β-Hydroxybutyrate
T. Hinds, J. Creeden, Darren M. Gordon, D. Stec +2 more
2020Frontiers in Pharmacology86 citations Open access
Semantic Scholar
RNA sequencing in human HepG2 hepatocytes reveals PPAR-α mediates transcriptome responsiveness of bilirubin.
Darren M. Gordon, Thomas M Blomquist, Scott A Miruzzi, R. McCullumsmith +2 more
2019Physiological Genomics66 citations Open access
Semantic Scholar
Loss of biliverdin reductase-A promotes lipid accumulation and lipotoxicity in mouse proximal tubule cells.
S. Adeosun, Darren M. Gordon, M. Weeks, K. Moore +3 more
2018AJP - Renal Physiology65 citations Open access
Semantic Scholar
Identification of Binding Regions of Bilirubin in the Ligand-Binding Pocket of the Peroxisome Proliferator-Activated Receptor-A (PPARalpha)
Darren M. Gordon, Stephen H Hong, Zachary A. Kipp, T. Hinds
2021Molecules51 citations Open access
Semantic Scholar
Biliverdin Reductase A (BVRA) Knockout in Adipocytes Induces Hypertrophy and Reduces Mitochondria in White Fat of Obese Mice
D. Stec, Darren M. Gordon, A. Nestor-Kalinoski, M. Donald +3 more
2020Biomolecules47 citations Open access
Semantic Scholar
CRISPR Cas9-mediated deletion of biliverdin reductase A (BVRA) in mouse liver cells induces oxidative stress and lipid accumulation.
Darren M. Gordon, S. Adeosun, Somtochukwu I. Ngwudike, C. Anderson +3 more
2019Archives of Biochemistry and Biophysics41 citations Open access
Semantic Scholar
Rats Genetically Selected for High Aerobic Exercise Capacity Have Elevated Plasma Bilirubin by Upregulation of Hepatic Biliverdin Reductase-A (BVRA) and Suppression of UGT1A1
T. Hinds, J. Creeden, Darren M. Gordon, Adam C Spegele +3 more
2020Antioxidants32 citations Open access
Semantic Scholar
Chronic Ethanol Consumption Alters Glucocorticoid Receptor Isoform Expression in Stress Neurocircuits and Mesocorticolimbic Brain Regions of Alcohol-Preferring Rats
H. Alhaddad, Darren M. Gordon, R. Bell, Erin E. Jarvis +3 more
2020Neuroscience17 citations Open access
Semantic Scholar
Bilirubin: A Ligand of the PPARα Nuclear Receptor
Stephen H Hong, Darren M. Gordon, D. Stec, T. Hinds
2021Nuclear Receptors12 citations
Semantic Scholar
Use of Multimodal Long-Wave Infrared Thermography Devices in Clinical Practice.
R. Simman, Darren M. Gordon, K. Klomparens, Frank Aviles
2023ePlasty: Open Access Journal of Plastic and Reconstructive Surgery2 citations
Semantic Scholar
Bilirubin nanoparticles activate PPARalpha to remodel the hepatic lipidome and produce hepatic ketones in obese mice, improving liver function
J. Creeden, Darren M. Gordon, Donald F. Stec, M. Donald +4 more
2021The FASEB Journal2 citations
Semantic Scholar
Bilirubin, a novel endocrine hormone with fat burning properties
T. Hinds, Darren M. Gordon, Shauna D. Combs, D. Stec
20182 citations
Semantic Scholar
Bilirubin: A Fat Busting Metabolic Hormone?
Darren M. Gordon, Scott Mizzuri, R. McCullumsmith, D. Stec +1 more
2020The FASEB Journal1 citations Open access
Semantic Scholar
Bilirubin Induces the Burning of Fat via the Nuclear Receptor PPARα
Darren M. Gordon, K. John, Christopher J. Trabbic, Amarjit Luniwal +4 more
20180 citations
Semantic Scholar

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