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Howard C. Shen · SciRah

Researcher profile · Semantic Scholar

Howard C. Shen

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Howard C. Shen — researcher profile on SciRah

h-index: 17
Works: 23
Citations: 2,090

Most-cited papers

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
S. Bojesen, K. Pooley, S. Johnatty, J. Beesley +433 more
2013Nature Genetics560 citations Open access
Semantic Scholar
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
P. Pharoah, Ya-Yu Tsai, S. Ramus, C. Phelan +164 more
2013Nature Genetics383 citations Open access
Semantic Scholar
Identification of six new susceptibility loci for invasive epithelial ovarian cancer
Karoline B. Kuchenbaecker, S. Ramus, J. Tyrer, Andrew Lee +285 more
2015Nature Genetics249 citations Open access
Semantic Scholar
Alzheimer’s and Parkinson’s disease
J. D. Adams, L. Klaidman, I. N. Odunze, Howard C. Shen +1 more
1991188 citations
Semantic Scholar
Identiﬁcation and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31
Jennifer Permuth-Wey, K. Lawrenson, Howard C. Shen
114 citations
Semantic Scholar
Galeterone Prevents Androgen Receptor Binding to Chromatin and Enhances Degradation of Mutant Androgen Receptor
Zi-Yang Yu, C. Cai, Shuai Gao, Nicholas I. Simon +2 more
2014Clinical Cancer Research88 citations Open access
Semantic Scholar
Androgen receptor activity at the prostate specific antigen locus: steroidal and non-steroidal mechanisms.
Jia Li, Joshua Kim, Howard C. Shen, P. Clark +2 more
2003Molecular Cancer Research73 citations
Semantic Scholar
Locus-Wide Chromatin Remodeling and Enhanced Androgen Receptor-Mediated Transcription in Recurrent Prostate Tumor Cells
Li Jia, Howard C. Shen, M. Wantroba, O. Khalid +7 more
2006Molecular and Cellular Biology65 citations Open access
Semantic Scholar
Structural Basis for Nuclear Receptor Corepressor (NCoR) Recruitment by Antagonist Liganded Androgen Receptor
M. Hodgson, Howard C. Shen, A. Hollenberg, S. Balk
2008Molecular Cancer Therapeutics57 citations Open access
Semantic Scholar
Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci.
Simon G. Coetzee, Howard C. Shen, Dennis J. Hazelett, K. Lawrenson +17 more
2015Human Molecular Genetics48 citations Open access
Semantic Scholar
Development of androgen receptor antagonists with promising activity in castration-resistant prostate cancer.
Howard C. Shen, S. Balk
2009Cancer Cell48 citations Open access
Semantic Scholar
The androgen receptor: unlocking the secrets of its unique transactivation domain.
Howard C. Shen, G. Coetzee
2005Vitamins and hormones46 citations
Semantic Scholar
Androgen receptor‐mediated repression of novel target genes
J. Prescott, U. Jariwala, Li Jia, J. Cogan +7 more
2007The Prostate43 citations
Semantic Scholar
GRIP1 mediates the interaction between the amino- and carboxyl-termini of the androgen receptor
Howard C. Shen, G. Buchanan, L. Butler, J. Prescott +3 more
2005Biological chemistry37 citations
Semantic Scholar
Functional analysis and fine mapping of the 9p22.2 ovarian cancer susceptibility locus
Melissa A. Buckley, Nicholas T. Woods, J. Tyrer, Gustavo A. Mendoza-Fandino +23 more
2018Cancer Research27 citations Open access
Semantic Scholar
Large-Scale Evaluation of Common Variation in Regulatory T Cell-Related Genes and Ovarian Cancer Outcome
Bridget Charbonneau, K. Moysich, K. Kalli, A. Oberg +101 more
2014Cancer immunology research24 citations Open access
Semantic Scholar
In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancer.
Howard C. Shen, K. Shanmugasundaram, Nicholas I. Simon, C. Cai +4 more
2012Molecular Endocrinology23 citations Open access
Semantic Scholar
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17 q 21 . 31
Jennifer Permuth-Wey, K. Lawrenson, Howard C. Shen, Aneliya Velkova +169 more
201313 citations
Semantic Scholar
Abstract PR15: MYC distal enhancers underlie ovarian cancer susceptibility in the 8q24.21 locus.
A. Gjyshi, Gustavo A. Mendoza-Fandino, Nicholas T. Woods, J. Tyrer +12 more
20161 citations
Semantic Scholar
Abstract 1380: Genome-wide fingerprinting of regulatory chromatin to evaluate the tissue specific origins of high-grade serous ovarian cancer
Howard C. Shen, Simon G. Coetzee, Dennis J. Hazelett, G. Coetzee +2 more
20140 citations
Semantic Scholar
Abstract 3285: Functional analysis of the 9p22 locus implicates the transcriptional regulation ofBNC2as a mechanism in ovarian cancer predisposition
Melissa A. Buckley, Howard C. Shen, Gustavo A. Mendoza-Fandino, Nicholas T. Woods +24 more
20140 citations
Semantic Scholar
Inhibiteurs du récepteur des androgènes et leurs procédés d'utilisation
Steven P. Balk, Alan C. Rigby, K. Shanmugasundaram, Howard C. Shen
20110 citations
Semantic Scholar
Functional analyses of androgen receptor structure pertaining to prostate cancer
Howard C. Shen
20070 citations
Semantic Scholar

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