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David Brunell · SciRah

Researcher profile · Semantic Scholar

David Brunell

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David Brunell — researcher profile on SciRah

h-index: 11
Works: 20
Citations: 378

Most-cited papers

Thionein can serve as a reducing agent for the methionine sulfoxide reductases.
D. Sagher, David Brunell, J. Hejtmancik, M. Kantorow +2 more
2006Proceedings of the National Academy of Sciences of the United States of America74 citations
Semantic Scholar
Driver network as a biomarker: systematic integration and network modeling of multi-omics data to derive driver signaling pathways for drug combination prediction
Lei Huang, David Brunell, C. Stephan, James J. Mancuso +7 more
2019Bioinform.53 citations Open access
Semantic Scholar
Selenocompounds Can Serve as Oxidoreductants with the Methionine Sulfoxide Reductase Enzymes*
D. Sagher, David Brunell, N. Brot, B. Vallee +1 more
2006Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Studies on the Metabolism and Biological Activity of the Epimers of Sulindac
David Brunell, D. Sagher, Shailaja Kesaraju, N. Brot +1 more
2011Drug Metabolism And Disposition41 citations Open access
Semantic Scholar
Sequential administration of XPO1 and ATR inhibitors enhances therapeutic response in TP53-mutated colorectal cancer
A. Inoue, Frederick S. Robinson, R. Minelli, Hideo Tomihara +31 more
2021Gastroenterology38 citations Open access
Semantic Scholar
Comprehensive pharmacogenomic profiling of human papillomavirus-positive and -negative squamous cell carcinoma identifies sensitivity to aurora kinase inhibition in KMT2D mutants.
Nene N. Kalu, T. Mazumdar, S. Peng, P. Tong +8 more
2018Cancer Letters30 citations
Semantic Scholar
Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma
M. Kogiso, Lin Qi, H. Lindsay, Yu-Lun Huang +24 more
2017OncoTarget24 citations Open access
Semantic Scholar
The polo-like kinase 1 inhibitor volasertib synergistically increases radiation efficacy in glioma stem cells
Jian-Wen Dong, S. Park, N. Nguyen, R. Ezhilarasan +11 more
2018OncoTarget20 citations Open access
Semantic Scholar
High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na+ channel complex
Paul A. Wadsworth, O. Folorunso, N. Nguyen, A. Singh +6 more
2019Scientific Reports17 citations Open access
Semantic Scholar
Apoptotic Gene Expression in Sinecatechins-Treated External Genital and Perianal Warts
Harrison P. Nguyen, H. Doan, David Brunell, P. Rady +1 more
2014Viral immunology17 citations
Semantic Scholar
A High-Throughput Screening Compatible Assay for Activators and Inhibitors of Methionine Sulfoxide Reductase A
David Brunell, H. Weissbach, P. Hodder, N. Brot
2010Assay and drug development technologies14 citations Open access
Semantic Scholar
Abstract 4669: Overcoming therapy resistance in stem cell-rich triple negative breast cancer through p38 MAP kinase inhibition
P. den Hollander, Shruti N. Shah, Xinhui Zhou, Abena B. Redwood +9 more
2019Tumor Biology2 citations Open access
Semantic Scholar
Abstract B20: Unbiased high-throughput screenings to identify combination therapies targeting RAS-mutated colorectal cancer
R. Powell, F. Fan, Mary Sobieski, David Brunell +5 more
2020Poster Presentations - Proffered Abstracts0 citations
Semantic Scholar
Abstract 4819: High-throughput screening of glioma stem-like cells (GSCs) identifies synergistic therapeutic combination of FGFR inhibitor and CDK4/6 inhibitor
Jian-Wen Dong, Emmanuel Martínez-Ledesma, N. Nguyen, Shaofang Wu +9 more
2018Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 4646: Pharmacogenomic screen identifiesKMT2Dmutations as a biomarker of sensitivity to Aurora kinase inhibition in head and neck and cervical squamous cell carcinoma
T. Mazumdar, Nene N. Kalu, S. Peng, P. Tong +7 more
2018Cancer Chemistry0 citations
Semantic Scholar
Apoptotic gene expression profile in Sinecatechin-treated external and genital warts
H. Doan, Harrison P. Nguyen, David Brunell, P. Rady +1 more
20160 citations
Semantic Scholar
Center for Molecular Biology and Biotechnology
David Brunell, D. Sagher, Shailaja Kesaraju, N. Brot +1 more
20110 citations
Semantic Scholar
Methionine sulfoxide reductases: Studies on the reducing requirements and role in the metabolism of sulindac
David Brunell
20090 citations
Semantic Scholar
Metabolism and Biological Activity of Sulindac and its Epimers
David Brunell, Maria A. Marchetti, E. Gamliel, D. Sagher +3 more
20090 citations
Semantic Scholar
The metabolism of the R and S epimers of sulindac and their ability to enhance the selective killing of cancer cells by oxidative stress
David Brunell, Maria A. Marchetti, L. Resnick, E. Gamliel +3 more
20080 citations
Semantic Scholar

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C. Stephan×10
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C. Stephan — researcher profile on SciRah
H. Weissbach×7
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N. Brot×6
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