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C. Pászty · SciRah

Researcher profile · Semantic Scholar

C. Pászty

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C. Pászty — researcher profile on SciRah

h-index: 22
Works: 39
Citations: 4,958

Most-cited papers

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength
Xiao-Dong Li, M. Ominsky, Qing-Tian Niu, Ning Sun +18 more
2008Journal of Bone and Mineral Research962 citations Open access
Semantic Scholar
Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis
Xiao-Dong Li, M. Ominsky, K. Warmington, S. Morony +16 more
2009Journal of Bone and Mineral Research777 citations
Semantic Scholar
Transgenic knockout mice with exclusively human sickle hemoglobin and sickle cell disease.
C. Pászty, C. M. Brion, E. Manci, H. Witkowska +3 more
1997Science472 citations
Semantic Scholar
Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength
M. Ominsky, Fay Vlasseros, J. Jolette, Susan Y. Smith +19 more
2010Journal of Bone and Mineral Research425 citations Open access
Semantic Scholar
Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice.
C. Pászty, N. Maeda, J. Verstuyft, E. Rubin
1994Journal of Clinical Investigation390 citations Open access
Semantic Scholar
Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones
M. Ominsky, Chaoyang Li, Xiao-Dong Li, Hong L. Tan +15 more
2011Journal of Bone and Mineral Research264 citations Open access
Semantic Scholar
Characterization of the Structural Features and Interactions of Sclerostin
V. Veverka, A. Henry, P. Slocombe, A. Ventom +12 more
2009Journal of Biological Chemistry254 citations Open access
Semantic Scholar
Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats
Xiao-Dong Li, K. Warmington, Qing-Tian Niu, F. Asuncion +11 more
2010Journal of Bone and Mineral Research243 citations
Semantic Scholar
Sclerostin antibody increases bone mass by stimulating bone formation and inhibiting bone resorption in a hindlimb-immobilization rat model.
Xiao-Yan Tian, W. Jee, Xiao-Dong Li, C. Pászty +1 more
2011Bone184 citations
Semantic Scholar
Sclerostin: A gem from the genome leads to bone‐building antibodies
C. Pászty, C. Turner, M. Robinson
2010Journal of Bone and Mineral Research142 citations Open access
Semantic Scholar
Protein 4.1R-deficient mice are viable but have erythroid membrane skeleton abnormalities.
Zheng-Tao Shi, Veena Afzal, B. Coller, D. Patel +10 more
1999Journal of Clinical Investigation130 citations Open access
Semantic Scholar
Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism.
J. Morrison, C. Pászty, M. E. Stevens, S. Hughes +3 more
1996Proceedings of the National Academy of Sciences of the United States of America94 citations Open access
Semantic Scholar
Increased bone formation and bone mass induced by sclerostin antibody is not affected by pretreatment or cotreatment with alendronate in osteopenic, ovariectomized rats.
Xiao-Dong Li, M. Ominsky, K. Warmington, Qing-Tian Niu +9 more
2011Endocrinology84 citations
Semantic Scholar
Sclerostin Inhibition Reverses Skeletal Fragility in an Lrp5-Deficient Mouse Model of OPPG Syndrome
R. Kedlaya, Shreya S. Veera, D. Horan, R. E. Moss +6 more
2013Science Translational Medicine80 citations Open access
Semantic Scholar
Lethal α–thalassaemia created by gene targeting in mice and its genetic rescue
C. Pászty, N. Mohandas, M. E. Stevens, J. Loring +3 more
1995Nature Genetics71 citations
Semantic Scholar
Increased callus mass and enhanced strength during fracture healing in mice lacking the sclerostin gene.
Chaoyang Li, M. Ominsky, Hong L. Tan, M. Barrero +7 more
2011Bone70 citations
Semantic Scholar
Transcriptional Profiling of Laser Capture Microdissected Subpopulations of the Osteoblast Lineage Provides Insight Into the Early Response to Sclerostin Antibody in Rats
P. Nioi, Scott Taylor, R. Hu, Efrain Pacheco +6 more
2015Journal of Bone and Mineral Research66 citations Open access
Semantic Scholar
Treatment with a sclerostin antibody increases cancellous bone formation and bone mass regardless of marrow composition in adult female rats.
Xiao-Yan Tian, R. Setterberg, Xiao-Dong Li, C. Pászty +2 more
2010Bone56 citations
Semantic Scholar
In vivo blood flow abnormalities in the transgenic knockout sickle cell mouse.
S. Embury, N. Mohandas, C. Pászty, P. Cooper +1 more
1999Journal of Clinical Investigation52 citations Open access
Semantic Scholar
Lethal alpha-thalassaemia created by gene targeting in mice and its genetic rescue.
C. Pászty, N. Mohandas, M. E. Stevens, J. Loring +3 more
1995Nature Genetics34 citations
Semantic Scholar
Transgenic and gene knock‐out mouse models of sickle cell anemia and the thalassemias
C. Pászty
1997Current opinion in hematology33 citations
Semantic Scholar
Rational design of an animal model for Alzheimer's disease: introduction of multiple human genomic transgenes to reproduce AD pathology in a rodent.
J. Loring, C. Pászty, A. Rose, T. McIntosh +7 more
1996Neurobiology of Aging28 citations Open access
Semantic Scholar
A plasmid-based method to quantitate homologous recombination frequencies in gram-negative bacteria.
Bi-Wen Xu, C. Pászty, P. Lurquin
1988BioTechniques17 citations
Semantic Scholar
Inhibition of transgene expression in plant protoplasts by the presence in cis of an opposing 3′-promoter
C. Pászty, P. Lurquin
199013 citations
Semantic Scholar
Inhibition of WISE preserves renal allograft function.
Xueming Qian, Xiaodong Yuan, S. Vonderfecht, X. Ge +22 more
2013Journal of the American Society of Nephrology8 citations Open access
Semantic Scholar
Electroporation of tobacco protoplasts with homologous and nonhomologous transformation vectors
P. Lurquin, C. Pászty
19885 citations
Semantic Scholar
Rapid Genotyping of Mice with Hemoglobinopathies and Globin Transgenes
J. Whitney, A. Leder, Jada Lewis, R. Popp +5 more
1998Biochemical Genetics4 citations
Semantic Scholar
Sclerostin is an Important Target for Stimulating Bone Formation, Restoring Bone Mass and Enhancing Fracture Healing
D. Ke, D. Padhi, C. Pászty
20102 citations
Semantic Scholar
A novel method to study DNA replication in vivo in organelles.
Henry Daniell, S. Kaliappan, M. Krishnan, C. Pászty
1993Nucleic Acids Research2 citations Open access
Semantic Scholar
Inhibition of sclerostin by treatment with anti-sclerostin antibody increased cancellous bone formation and decreased bone resorption in both high and low turnover bone sites in female rats
X.-Y. Tian, W. Jee, R. Setterberg, M. Chen +4 more
20081 citations
Semantic Scholar
Rapid Publication Magnetic Resonance Evidence of Hypoxia in a Homozygous Alpha-Knockout of a Transgenic Mouse Model for Sickle Cell Disease
M. Fabry, R. Kennan, C. Pászty, F. Costantini +3 more
20130 citations
Semantic Scholar
Rajendra Kedlaya Mouse Model of OPPG Syndrome Sclerostin Inhibition Reverses Skeletal Fragility in an Lrp 5-Deficient
R. Kedlaya, Shreya S. Veera, D. Horan, R. E. Moss +6 more
20130 citations
Semantic Scholar
Home > Anatomy & Physiology > Anatomy & Physiology > Journal Home > Accepted Articles > Abstract
M. Ominsky, Chaoyang Li, Xiao-Dong Li, Hong L. Tan +15 more
20110 citations
Semantic Scholar
MODULATION OF THE WNT SIGNALING PATHWAY BY WISE ANTIBODY IMPROVES LONG-TERM KIDNEY TRANSPLANT OUTCOME IN A RAT RENAL TRANSPLANT MODEL: 1398
X. Yuan, S. Vonderfecht, X. Ge, Jae Lee +14 more
20100 citations
Semantic Scholar
Binding antibodies sclerostin
H. Lu, C. Pászty, M. Robinson, A. Henry +5 more
20060 citations
Semantic Scholar
Stomatocytosis is absent in 'stomatin'-deficient mouse red cells
Yiwen Zhu, C. Pászty, T. Turetsky, Susan Tsai +8 more
20010 citations
Semantic Scholar
Polypeptide and glycoprotein hormone heterodimer similar to beta.
Jinguo Cao, D. Danilenko, Jianhua Gong, D. C. Hill +1 more
20010 citations
Semantic Scholar
Sickle cell disease: a step closer to the dream.
N. Mohandas, C. Pászty
1996Journal of Clinical Investigation0 citations Open access
Semantic Scholar
Rapid Publication
C. Pászty, N. Maeda, Judy, Verstuyft +1 more
0 citations
Semantic Scholar

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