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B. Hastoy · SciRah

Researcher profile · Semantic Scholar

B. Hastoy

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B. Hastoy — researcher profile on SciRah

h-index: 16
Works: 54
Citations: 1,597

Most-cited papers

MicroRNA-7a regulates pancreatic β cell function.
M. Latreille, Jean Hausser, Ina Stützer, Quan Zhang +10 more
2014Journal of Clinical Investigation257 citations Open access
Semantic Scholar
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.
M. Shigeto, R. Ramracheya, A. Tarasov, Chae Y. Cha +19 more
2015Journal of Clinical Investigation168 citations Open access
Semantic Scholar
Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion
Ghupurjan Gheni, M. Ogura, Masahiro Iwasaki, N. Yokoi +18 more
2014Cell Reports158 citations Open access
Semantic Scholar
Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion
E. Vergari, J. G. Knudsen, R. Ramracheya, A. Salehi +16 more
2019Nature Communications144 citations Open access
Semantic Scholar
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion
O. Dwivedi, M. Lehtovirta, B. Hastoy, V. Chandra +43 more
2018Nature Genetics125 citations Open access
Semantic Scholar
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
J. Ast, A. Arvaniti, N. H. Fine, Daniela Nasteska +22 more
2020Nature Communications123 citations Open access
Semantic Scholar
The β-cell assassin: IAPP cytotoxicity.
D. Raleigh, Xiaoxue Zhang, B. Hastoy, A. Clark
2017Journal of Molecular Endocrinology104 citations
Semantic Scholar
RFX6 regulates insulin secretion by modulating Ca2+ homeostasis in human β cells.
V. Chandra, O. Albagli-Curiel, B. Hastoy, Julie Piccand +9 more
2014Cell Reports91 citations Open access
Semantic Scholar
AP2σ Mutations Impair Calcium-Sensing Receptor Trafficking and Signaling, and Show an Endosomal Pathway to Spatially Direct G-Protein Selectivity
C. Gorvin, A. Rogers, B. Hastoy, A. Tarasov +8 more
2018Cell Reports78 citations Open access
Semantic Scholar
Type 2 Diabetes Risk Alleles in PAM Impact Insulin Release from Human Pancreatic Beta Cells
Soren K. Thomsen, Anne Raimondo, B. Hastoy, S. Sengupta +16 more
2018Nature Genetics69 citations Open access
Semantic Scholar
Increased expression of the diabetes gene SOX4 reduces insulin secretion by impaired fusion pore expansion
S. Collins, H. Do, B. Hastoy, Alison J. Hugill +11 more
2016Diabetes60 citations Open access
Semantic Scholar
Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells
B. Hastoy, M. Godazgar, A. Clark, Vibe Nylander +9 more
2018Scientific Reports42 citations Open access
Semantic Scholar
A Central Small Amino Acid in the VAMP2 Transmembrane Domain Regulates the Fusion Pore in Exocytosis
B. Hastoy, P. Scotti, Alexandra Milochau, Zahia Fezoua-Boubegtiten +9 more
2017Scientific Reports28 citations Open access
Semantic Scholar
A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function
A. Grotz, F. Abaitua, Elena Navarro-Guerrero, B. Hastoy +2 more
2019Wellcome Open Research23 citations Open access
Semantic Scholar
NKX6.1 induced pluripotent stem cell reporter lines for isolation and analysis of functionally relevant neuronal and pancreas populations.
S. Gupta, Agata Wesolowska-Andersen, Anna K. Ringgaard, Himjyot Jaiswal +16 more
2018Stem Cell Research23 citations Open access
Semantic Scholar
Fusion pore in exocytosis: More than an exit gate? A β-cell perspective.
B. Hastoy, A. Clark, P. Rorsman, J. Lang
2017Cell Calcium20 citations Open access
Semantic Scholar
Platelet‐derived lipids promote insulin secretion of pancreatic β cells
Till Karwen, Katarzyna Kolczyńska-Matysiak, Carina Gross, Mona C. Löffler +19 more
2023EMBO Molecular Medicine14 citations Open access
Semantic Scholar
Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation
N. Ng, Sara M. Willems, Juan Fernandez, Rebecca S. Fine +260 more
2019bioRxiv10 citations Open access
Semantic Scholar
Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion
Ming Hu, Inês Cebola, Gaelle R. Carrat, Shuying Jiang +14 more
2021Cell Reports9 citations Open access
Semantic Scholar
Electrophysiological characterisation of iPSC-derived human β-like cells and an SLC30A8 disease model.
Manon Jaffredo, Nicole A. J. Krentz, Benoite Champon, Claire E. Duff +9 more
2024Diabetes8 citations Open access
Semantic Scholar
The transmembrane domain of the SNARE protein VAMP2 is highly sensitive to its lipid environment.
Zahia Fezoua-Boubegtiten, B. Hastoy, P. Scotti, Alexandra Milochau +5 more
2019Biochimica et Biophysica Acta - Biomembranes7 citations Open access
Semantic Scholar
Loss of tetraspanin‐7 expression reduces pancreatic β‐cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism
K. McLaughlin, S. Acreman, Sameena Nawaz, J. Cutteridge +9 more
2022Diabetic Medicine6 citations Open access
Semantic Scholar
Roles for the long non-coding RNA Pax6os1/PAX6-AS1 in pancreatic beta cell function
Livia Lopez-Noriega, Rebecca M. Callingham, Aida Martinez-Sánchez, Sameena Nawaz +15 more
2024iScience4 citations Open access
Semantic Scholar
Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists
M. Umapathysivam, E. Araldi, B. Hastoy, A. Dawed +28 more
2023medRxiv4 citations Open access
Semantic Scholar
Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
J. Ast, A. Arvaniti, N. H. Fine, Daniela Nasteska +22 more
2020Nature Communications4 citations Open access
Semantic Scholar
Roles for the long non-coding RNA Pax6os1/PAX6-AS1 in pancreatic beta cell identity and function
Livia Lopez-Noriega, Rebecca M. Callingham, Aida Martinez-Sánchez, Sameena Nawaz +15 more
2020bioRxiv4 citations Open access
Semantic Scholar
Type 2 Diabetes Risk Alleles Reveal a Role for Peptidylglycine Alpha-amidating Monooxygenase in Beta Cell Function
Anne Raimondo, Soren K. Thomsen, B. Hastoy, M. Umapathysivam +10 more
2017bioRxiv4 citations Open access
Semantic Scholar
Electrophysiological characterisation of iPSC-derived human β-like cells and an SLC30A8 disease model
Manon Jaffredo, Nicole A. J. Krentz, Benoite Champon, Claire E. Duff +9 more
2023bioRxiv3 citations Open access
Semantic Scholar
Electrophysiological properties of human β-cell lines EndoC-βH1 and -βH2 conform with human β-cells
B. Hastoy, M. Godazgar, A. Clark, Vibe Nylander +9 more
2017bioRxiv3 citations Open access
Semantic Scholar
338.2: Oxygenated hypothermic machine perfusion of the pancreas; a porcine circulatory death model to compare a ‘continuous’ and an ‘end-ischaemic’ approach
Mohamed Elzawahry, J. Fallon, Sameena Nawaz, B. Hastoy +4 more
2023Transplantation2 citations Open access
Semantic Scholar
LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
J. Ast, A. Arvaniti, N. H. Fine, Daniela Nasteska +16 more
2019bioRxiv2 citations Open access
Semantic Scholar
Type 2 diabetes risk alleles in peptidyl-glycine alpha-amidating monooxygenase influence GLP-1 levels and response to GLP-1 receptor agonists
M. Umapathysivam, Elisa Araldi, B. Hastoy, A. Dawed +41 more
2026Genome Medicine1 citations Open access
Semantic Scholar
Comparison of “Continuous” and “End-ischemic” Approaches of Oxygenated Hypothermic Machine Perfusion for Pancreas Preservation
Mohamed A Elzawahry, J. Fallon, B. Hastoy, M. L. Lo Faro +6 more
2026Transplantation Direct1 citations Open access
Semantic Scholar
7700 Two Years Of Testosterone Therapy Reduces Glycemia In Males At High Risk Of Type 2 Diabetes Without Affecting Beta Cell Function: Results From A Randomised Controlled Trial And Cellular Model
M. Umapathysivam, S. Nawaz, K. Robledo, C. Allan +12 more
2024Journal of the Endocrine Society1 citations Open access
Semantic Scholar
Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion
Ming Hu, Inês Cebola, Gaelle R. Carrat, Shuying Jiang +14 more
2021Cell Reports1 citations Open access
Semantic Scholar
AP2 mutations impair calcium-sensing receptor trafficking and signaling revealing an endosomal pathway that spatially directs G-protein selectivity
C. Gorvin, A. Rogers, B. Hastoy, A. Tarasov +8 more
20181 citations
Semantic Scholar
A Central Small Amino Acid in the VAMP2 Transmembrane Domain Regulates the Fusion Pore in Exocytosis
B. Hastoy, P. Scotti, Alexandra Milochau, Zahia Fezoua-Boubegtiten +9 more
2017Scientific Reports1 citations Open access
Semantic Scholar
An Explainable Deep Learning Framework for Imaging Genetics: Deriving Brain-Genotype Scores From MRI to Link Genetic Variation, Brain Structure, and Cognition
K. Alhasani, U. Ghose, J. Sammet, T. Zhu +9 more
2026medRxiv0 citations Open access
Semantic Scholar
Ticking Differently: Elucidating Sexual Dimorphism in Human Aging through Metabolomics, Proteomics and Genomics
Si-Hao Xiao, Pallavi Kaushik, Gaoyu Du, Bowen Liu +8 more
2025medRxiv0 citations Open access
Semantic Scholar
Mitochondrial movement in pancreatic alpha cells requires Miro2 and is regulated by glucose
Maia H. Ekstrand, Sameena Nawaz, Anne Clark, B. Hastoy +1 more
2025Journal of Biological Chemistry0 citations Open access
Semantic Scholar
O225: Oxygenated hypothermic machine perfusion (HMPO2) of the pancreas; a porcine circulatory death model to compare a ‘continuous’ and an ‘end-ischaemic’ approach
Mohamed Elzawahry, J. Fallon, Sameena Nawaz, B. Hastoy +4 more
2024British Journal of Surgery0 citations
Semantic Scholar
25-OR: Investigating a Candidate Causal Allele in Type 2 Diabetes Susceptibility Gene PAM as a Cause of Neonatal Diabetes Mellitus
S. Sengupta, L. Bonnycastle, B. Hastoy, A. Grotz +9 more
2019Diabetes0 citations
Semantic Scholar
Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion
E. Vergari, J. G. Knudsen, R. Ramracheya, A. Salehi +16 more
2019Nature Communications0 citations Open access
Semantic Scholar
University of Southern Denmark AP2σ Mutations Impair Calcium-Sensing Receptor Trafficking and Signaling, and Show an Endosomal Pathway to Spatially Direct G-Protein Selectivity Mutations Impair Calcium-Sensing Receptor Trafficking and Signaling, and Show an Endosomal Pathway to Spatially Direct G-Pr
C. Gorvin, A. Rogers, B. Hastoy, A. Tarasov +8 more
20180 citations
Semantic Scholar
Type-2 Diabetes - A Fusion Pore Disease?
P. Rorsman, S. Collins, B. Hastoy
20180 citations Open access
Semantic Scholar
The Calcium-Sensing Receptor, a Class C GPCR, Spatially-Directs G-protein Selectivity via Endosomal Signaling.
C. Gorvin, A. Rogers, B. Hastoy, A. Tarasov +7 more
20170 citations
Semantic Scholar
Role of the VAMP2 transmembrane domain in exocytosis
B. Hastoy, J. Lang
20170 citations
Semantic Scholar
Type 2 Diabetes Risk Variants in PAM Reduce Chromogranin A-mediated Insulin Availability and Secretion from Beta Cells
Anne Raimondo, Soren K. Thomsen, B. Hastoy, M. Umapathysivam +6 more
20160 citations
Semantic Scholar
Electrophysiological characterisation of the human beta cell line EndoC-beta H2
B. Hastoy, M. Chibalina, M. Godazgar, R. Scharfmann +1 more
20150 citations
Semantic Scholar
Calcium-sensing receptor internalisation is impaired in cells expressing FHH3-associated AP2σ mutations
C. Gorvin, B. Hastoy, G. Breitwieser, P. Rorsman +1 more
20150 citations
Semantic Scholar

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