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W. Hummel · SciRah

Researcher profile · Semantic Scholar

W. Hummel

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W. Hummel — researcher profile on SciRah

h-index: 51
Works: 214
Citations: 7,262

Most-cited papers

Regeneration of nicotinamide coenzymes: principles and applications for the synthesis of chiral compounds.
A. Weckbecker, H. Gröger, W. Hummel
2010Advances in Biochemical Engineering/Biotechnology196 citations
Semantic Scholar
Combining the 'two worlds' of chemocatalysis and biocatalysis towards multi-step one-pot processes in aqueous media.
H. Gröger, W. Hummel
2014Current Opinion in Chemical Biology188 citations
Semantic Scholar
An enzyme cascade synthesis of ε-caprolactone and its oligomers.
Sandy Schmidt, Christian Scherkus, Jan Muschiol, U. Menyes +6 more
2015Angewandte Chemie169 citations
Semantic Scholar
Enantioselective reduction of ketones with "designer cells" at high substrate concentrations: highly efficient access to functionalized optically active alcohols.
H. Gröger, F. Chamouleau, Nicolas Orologas, Claudia Rollmann +4 more
2006Angewandte Chemie155 citations
Semantic Scholar
Modular chemoenzymatic one-pot syntheses in aqueous media: combination of a palladium-catalyzed cross-coupling with an asymmetric biotransformation.
Edyta Burda, W. Hummel, H. Gröger
2008Angewandte Chemie139 citations
Semantic Scholar
Cloning, expression, and characterization of an (R)-specific alcohol dehydrogenase from Lactobacillus kefir
A. Weckbecker, W. Hummel
2006136 citations
Semantic Scholar
Sequential and modular synthesis of chiral 1,3-diols with two stereogenic centers: access to all four stereoisomers by combination of organo- and biocatalysis.
Katrin Baer, Marina Krausser, Edyta Burda, W. Hummel +2 more
2009Angewandte Chemie115 citations
Semantic Scholar
Strategies for regeneration of nicotinamide coenzymes emphasizing self-sufficient closed-loop recycling systems.
W. Hummel, H. Gröger
2014Journal of Biotechnology110 citations
Semantic Scholar
Cooperative catalysis of noncompatible catalysts through compartmentalization: wacker oxidation and enzymatic reduction in a one-pot process in aqueous media.
Hirofumi Sato, W. Hummel, H. Gröger
2015Angewandte Chemie99 citations
Semantic Scholar
Threonine aldolases—screening, properties and applications in the synthesis of non-proteinogenic β-hydroxy-α-amino acids
Nina Dückers, Katrin Baer, Sabine Simon, H. Gröger +1 more
2010Applied Microbiology and Biotechnology99 citations
Semantic Scholar
Combination of Asymmetric Organo- and Biocatalytic Reactions in Organic Media Using Immobilized Catalysts in Different Compartments
Marcel Heidlindemann, Giuseppe Rulli, A. Berkessel, W. Hummel +1 more
201489 citations
Semantic Scholar
Direction of kinetically versus thermodynamically controlled organocatalysis and its application in chemoenzymatic synthesis.
Giuseppe Rulli, N. Duangdee, Katrin Baer, W. Hummel +2 more
2011Angewandte Chemie88 citations
Semantic Scholar
The structure of a bacterial L-amino acid oxidase from Rhodococcus opacus gives new evidence for the hydride mechanism for dehydrogenation.
A. Faust, K. Niefind, W. Hummel, D. Schomburg
2007Journal of Molecular Biology87 citations
Semantic Scholar
Enzymatic routes for the synthesis of ursodeoxycholic acid.
T. Eggert, Daniel Bakonyi, W. Hummel
2014Journal of Biotechnology75 citations
Semantic Scholar
Direct biocatalytic one-pot-transformation of cyclohexanol with molecular oxygen into ɛ-caprolactone.
Svenja Staudt, U. Bornscheuer, U. Menyes, W. Hummel +1 more
2013Enzyme and Microbial Technology70 citations
Semantic Scholar
Characterization of a whole‐cell catalyst co‐expressing glycerol dehydrogenase and glucose dehydrogenase and its application in the synthesis of L‐glyceraldehyde
Nina Richter, Markus Neumann, A. Liese, Roland Wohlgemuth +3 more
2010Biotechnology and Bioengineering62 citations
Semantic Scholar
Direct oxidation of cycloalkanes to cycloalkanones with oxygen in water.
Svenja Staudt, Edyta Burda, Carolin Giese, C. A. Müller +5 more
2013Angewandte Chemie60 citations
Semantic Scholar
Continuous asymmetric ketone reduction processes with recombinant Escherichia coli.
K. Schroer, Ursula Mackfeld, Ivy Ai Vee. Tan, C. Wandrey +8 more
2007Journal of Biotechnology59 citations
Semantic Scholar
Iron catalysis for in situ regeneration of oxidized cofactors by activation and reduction of molecular oxygen: a synthetic metalloporphyrin as a biomimetic NAD(P)H oxidase.
H. Maid, Philipp Böhm, S. Huber, W. Bauer +3 more
2011Angewandte Chemie58 citations
Semantic Scholar
Asymmetric reduction of activated alkenes using an enoate reductase from Gluconobacter oxydans
Nina Richter, H. Gröger, W. Hummel
2010Applied Microbiology and Biotechnology58 citations
Semantic Scholar
Formal asymmetric hydration of non-activated alkenes in aqueous medium through a "chemoenzymatic catalytic system".
I. Schnapperelle, W. Hummel, H. Gröger
2012Chemistry55 citations
Semantic Scholar
Chemoenzymatic synthesis of the chiral side-chain of statins: application of an alcohol dehydrogenase catalysed ketone reduction on a large scale
M. Wolberg, M. Villela, S. Bode, Petra Geilenkirchen +4 more
2008Bioprocess and biosystems engineering (Print)55 citations
Semantic Scholar
Novel biocatalysts for white biotechnology
T. Drepper, T. Eggert, W. Hummel, C. Leggewie +4 more
2006Biotechnology Journal51 citations
Semantic Scholar
Glucose Dehydrogenase for the Regeneration of NADPH and NADH
A. Weckbecker, W. Hummel
200547 citations
Semantic Scholar
Combination of a Suzuki cross-coupling reaction using a water-soluble palladium catalyst with an asymmetric enzymatic reduction towards a one-pot process in aqueous medium at room temperature
Sonja Borchert, Edyta Burda, J. Schatz, W. Hummel +1 more
201246 citations
Semantic Scholar
Characterisation of a Recombinant NADP‐Dependent Glycerol Dehydrogenase from Gluconobacter oxydans and its Application in the Production of L‐Glyceraldehyde
Nina Richter, Markus Neumann, A. Liese, Roland Wohlgemuth +2 more
2009ChemBioChem45 citations
Semantic Scholar
Enantio‐ and Diastereoselective Chemoenzymatic Synthesis of C2‐Symmetric Biaryl‐Containing Diols
Edyta Burda, W. Bauer, W. Hummel, H. Gröger
201042 citations
Semantic Scholar
In Vitro Double Oxidation of n-Heptane with Direct Cofactor Regeneration
C. A. Müller, Beneeta Akkapurathu, Till Winkler, Svenja Staudt +3 more
201340 citations
Semantic Scholar
A single‐point mutation enables lactate dehydrogenase from Bacillus subtilis to utilize NAD+ and NADP+ as cofactor
Nina Richter, Anke Y. Zienert, W. Hummel
201139 citations
Semantic Scholar
Recombinant Δ4,5‐Steroid 5 β‐Reductases as Biocatalysts for the Reduction of Activated CC‐Double Bonds in Monocyclic and Acyclic Molecules
Edyta Burda, Marina Krausser, G. Fischer, W. Hummel +3 more
200939 citations
Semantic Scholar
The Organic–Synthetic Potential of Recombinant Ene Reductases: Substrate‐Scope Evaluation and Process Optimization
Tina Ress, W. Hummel, Steven Hanlon, H. Iding +1 more
201537 citations
Semantic Scholar
Highly efficient and stereoselective biosynthesis of (2S,5S)-hexanediol with a dehydrogenase from Saccharomyces cerevisiae.
Marion Müller, M. Katzberg, M. Bertau, W. Hummel
2010Organic and biomolecular chemistry33 citations
Semantic Scholar
Cloning, expression, and biochemical characterization of a novel NADP+-dependent 7α-hydroxysteroid dehydrogenase from Clostridium difficile and its application for the oxidation of bile acids.
Daniel Bakonyi, W. Hummel
2017Enzyme and Microbial Technology32 citations
Semantic Scholar
Guerbet Alcohols: From Processes under Harsh Conditions to Synthesis at Room Temperature under Ambient Pressure
Marc Biermann, H. Gruß, W. Hummel, H. Gröger
201631 citations
Semantic Scholar
Highly enantioselective reduction of α-methylated nitroalkenes.
Edyta Burda, Tina Ress, Till Winkler, Carolin Giese +4 more
2013Angewandte Chemie29 citations
Semantic Scholar
Enantioselective one-pot two-step synthesis of hydrophobic allylic alcohols in aqueous medium through the combination of a wittig reaction and an enzymatic ketone reduction
Marina Krausser, W. Hummel, H. Gröger
200728 citations
Semantic Scholar
Whole-cell double oxidation of n-heptane.
C. A. Müller, Alexander Dennig, T. Welters, Till Winkler +4 more
2014Journal of Biotechnology27 citations
Semantic Scholar
Chemoenzymatic synthesis of vitamin B5-intermediate (R)-pantolactone via combined asymmetric organo- and biocatalysis.
Marcel Heidlindemann, Matthias Hammel, U. Scheffler, R. Mahrwald +3 more
2015Journal of Organic Chemistry26 citations
Semantic Scholar
Cofactor engineering of Lactobacillus brevis alcohol dehydrogenase by computational design
Ronnie Machielsen, L. Looger, John Raedts, S. Dijkhuizen +4 more
200926 citations Open access
Semantic Scholar
Biochemical characterisation of a NADPH-dependent carbonyl reductase from Neurospora crassa reducing α- and β-keto esters.
Nina Richter, W. Hummel
2011Enzyme and Microbial Technology24 citations
Semantic Scholar
BIOTECHNOLOGICALLY RELEVANT ENZYMES AND PROTEINS Overproduction and characterization of a recombinant D-amino acid oxidase from Arthrobacter protophormiae
B. Geueke, A. Weckbecker, W. Hummel
200724 citations
Semantic Scholar
Integrated Biocatalysis in Multistep Drug Synthesis without Intermediate Isolation: A de Novo Approach toward a Rosuvastatin Key Building Block
R. Metzner, W. Hummel, F. Wetterich, Burghard König +1 more
201523 citations
Semantic Scholar
Combination of CC Bond Formation by Wittig Reaction and Enzymatic CC Bond Reduction in a One‐Pot Process in Water
Marina Krausser, Till Winkler, Nina Richter, Sabine Dommer +3 more
201123 citations
Semantic Scholar
Enzyme Module Systems for the Synthesis of Uridine 5′‐Diphospho‐α‐D‐glucuronic Acid and Non‐Sulfated Human Natural Killer Cell‐1 (HNK‐1) Epitope
Leonie Engels, Manja Henze, W. Hummel, L. Elling
201522 citations
Semantic Scholar
α-Hydroxy-β-keto acid rearrangement-decarboxylation: impact on thiamine diphosphate-dependent enzymatic transformations.
M. Beigi, S. Loschonsky, Patrizia Lehwald, V. Brecht +4 more
2013Organic and biomolecular chemistry22 citations
Semantic Scholar
Modelling of l-DOPA enzymatic oxidation catalyzed by l-amino acid oxidases from Crotalus adamanteus and Rhodococcus opacus
Z. Findrik, B. Geueke, W. Hummel, Đ. Vasić-Rac̆ki
200622 citations
Semantic Scholar
Process Development through Solvent Engineering in the Biocatalytic Synthesis of the Heterocyclic Bulk Chemical ε-Caprolactone
A. Reimer, S. Wedde, Svenja Staudt, Sandy Schmidt +5 more
201721 citations
Semantic Scholar
Biocatalytical production of (5S)-hydroxy-2-hexanone.
M. Katzberg, K. Wechler, Marion Müller, Pascal Dünkelmann +3 more
2009Organic and biomolecular chemistry21 citations
Semantic Scholar
First Tandem‐Type One‐Pot Process Combining Asymmetric Organo‐ and Biocatalytic Reactions in Aqueous Media Exemplified for the Enantioselective and Diastereoselective Synthesis of 1,3‐Diols
Giuseppe Rulli, N. Duangdee, W. Hummel, A. Berkessel +1 more
201720 citations
Semantic Scholar
Towards catalyst compartimentation in combined chemo- and biocatalytic processes: immobilization of alcohol dehydrogenases for the diastereoselective reduction of a β-hydroxy ketone obtained from an organocatalytic aldol reaction.
Giuseppe Rulli, Marcel Heidlindemann, A. Berkessel, W. Hummel +1 more
2013Journal of Biotechnology20 citations
Semantic Scholar

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