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Amber J. Giles · SciRah

Researcher profile · Semantic Scholar

Amber J. Giles

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Amber J. Giles — researcher profile on SciRah

h-index: 19
Works: 47
Citations: 3,274

Most-cited papers

Disruption of CXCR2-Mediated MDSC Tumor Trafficking Enhances Anti-PD1 Efficacy
S. Highfill, Yong-Zhi Cui, Amber J. Giles, Jillian P. Smith +4 more
2014Science Translational Medicine725 citations Open access
Semantic Scholar
T Cell Exhaustion Signatures Vary with Tumor Type and are Severe in Glioblastoma
K. Woroniecka, Pakawat Chongsathidkiet, Kristen E. Rhodin, Hanna R. Kemeny +18 more
2018Clinical Cancer Research555 citations Open access
Semantic Scholar
Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy
Amber J. Giles, Marsha-Kay N. D. Hutchinson, H. Sonnemann, Jinkyu Jung +9 more
2018Journal of Immunotherapy for Cancer457 citations Open access
Semantic Scholar
Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver
Y. Li, Shanqin Xu, Amber J. Giles, Kazuto Nakamura +8 more
2011The FASEB Journal310 citations Open access
Semantic Scholar
Hepatic SIRT1 Attenuates Hepatic Steatosis and Controls Energy Balance in Mice by Inducing Fibroblast Growth Factor 21
Yu Li, Kimberly Wong, Amber J. Giles, Jianwei Jiang +7 more
2013Gastroenterology276 citations Open access
Semantic Scholar
Hypoxia in the glioblastoma microenvironment: shaping the phenotype of cancer stem-like cells
N. Colwell, M. Larion, Amber J. Giles, Ashlee N. Seldomridge +3 more
2017Neuro-Oncology245 citations Open access
Semantic Scholar
Activation of hematopoietic stem/progenitor cells promotes immunosuppression within the pre-metastatic niche
Amber J. Giles, Caitlin M. Reid, J. Evans, Meera Murgai +8 more
2015Cancer Research141 citations Open access
Semantic Scholar
Immunotherapy in CNS cancers: the role of immune cell trafficking
Nivedita M. Ratnam, M. Gilbert, Amber J. Giles
2019Neuro-Oncology105 citations Open access
Semantic Scholar
Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma
Jinkyu Jung, Ying Zhang, O. Celiku, Wei Zhang +7 more
2019Cancer Research82 citations Open access
Semantic Scholar
Efficient ADCC- killing of meningioma by avelumab and a high-affinity natural killer cell line, haNK.
Amber J. Giles, Shu-Yu Hao, M. Padget, Hua Song +17 more
2019JCI Insight55 citations Open access
Semantic Scholar
OMIP‐050: A 28‐color/30‐parameter Fluorescence Flow Cytometry Panel to Enumerate and Characterize Cells Expressing a Wide Array of Immune Checkpoint Molecules
Leonard Nettey, Amber J. Giles, Pratip K. Chattopadhyay
2018Cytometry Part A44 citations Open access
Semantic Scholar
T lymphocyte-targeted immune checkpoint modulation in glioma
W. Kelly, Amber J. Giles, M. Gilbert
2020Journal for ImmunoTherapy of Cancer37 citations Open access
Semantic Scholar
Cardiac glycosides suppress the maintenance of stemness and malignancy via inhibiting HIF-1α in human glioma stem cells
D. Lee, S. Oh, Amber J. Giles, Jinkyu Jung +2 more
2017OncoTarget34 citations Open access
Semantic Scholar
Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade
John P. Lynes, Sadhana Jackson, Victoria E. Sanchez, Gifty A. Dominah +18 more
2018Neurosurgery33 citations Open access
Semantic Scholar
The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking
A. Soeda, J. Lathia, B. Williams, Qiulian Wu +8 more
2017OncoTarget30 citations Open access
Semantic Scholar
Programmed Death Ligand 1 Is a Negative Prognostic Marker in Recurrent Isocitrate Dehydrogenase-Wildtype Glioblastoma.
D. Pratt, Gifty A. Dominah, Graham P. Lobel, Arnold Obungu +11 more
2018Neurosurgery29 citations Open access
Semantic Scholar
Reversing Epigenetic Gene Silencing to Overcome Immune Evasion in CNS Malignancies
Nivedita M. Ratnam, H. Sonnemann, S. Frederico, Huanwen Chen +11 more
2021Frontiers in Oncology26 citations Open access
Semantic Scholar
Protein phosphatase 2A inhibition enhances radiation sensitivity and reduces tumor growth in chordoma
Shu-Yu Hao, Hua Song, Wei Zhang, Ashlee N. Seldomridge +15 more
2018Neuro-Oncology25 citations Open access
Semantic Scholar
The functional interplay between systemic cancer and the hematopoietic stem cell niche
Amber J. Giles, Christopher D. Chien, Caitlin M. Reid, T. Fry +3 more
2016Pharmacology and Therapeutics21 citations Open access
Semantic Scholar
Physiological, Tumor, and Metastatic Niches: Opportunities and Challenges for Targeting the Tumor Microenvironment
Meera Murgai, Amber J. Giles, R. Kaplan
2015Critical reviews in oncogenesis18 citations Open access
Semantic Scholar
A novel in vitro device to deliver induced electromagnetic fields to cell and tissue cultures.
R. Ravin, Teddy X. Cai, Randall Pursley, Marcial Garmendia-Cedillos +8 more
2020Biophysical Journal8 citations Open access
Semantic Scholar
The Adaptor Protein Shc Plays a Key Role During Early B Cell Development
Amber J. Giles, T. Bender, K. Ravichandran
2009Journal of Immunology8 citations Open access
Semantic Scholar
ShcA Regulates Thymocyte Proliferation through Specific Transcription Factors and a c-Abl-Dependent Signaling Axis
P. Trampont, Li Zhang, Amber J. Giles, Scott F. Walk +3 more
2015Molecular and Cellular Biology5 citations Open access
Semantic Scholar
Abstract 4126: CSF-1R inhibition blocks rhabdomyoscarcoma metastasis by polarizing macrophage differentiation
J. Evans, Amber J. Giles, Caitlin M. Reid, R. Kaplan
20152 citations
Semantic Scholar
Abstract 3962: High-dimensional flow cytometric immune profiling of malignant gliomas
Amber J. Giles, Caitlin M. Reid, Deric M. Park, M. Roederer +1 more
20171 citations
Semantic Scholar
METB-08. INCREASING GLUCOSE CONCENTRATIONS IS DELETERIOUS TO Th1 AND CYTOTOXIC T CELLS
Amber J. Giles
20161 citations
Semantic Scholar
Bone marrow-derived progenitor cells develop into myeloid-derived suppressor cells at metastatic sites
Amber J. Giles, Y. Vicioso, M. Kasai, S. Highfill +2 more
2013Journal of Immunotherapy for Cancer1 citations Open access
Semantic Scholar
Abstract LB-284: Bone marrow-derived progenitor cells develop into myeloid-derived suppressor cells at metastatic sites.
Amber J. Giles, Y. Vicioso, Christianne Persenaire, M. Kasai +3 more
20131 citations
Semantic Scholar
Abstract B5: Reversing epigenetic gene silencing to overcome immune evasion in CNS malignancies
Nivedita M. Ratnam, H. Sonnemann, M. Gilbert, Amber J. Giles
2020Poster Presentations - Proffered Abstracts0 citations
Semantic Scholar
Abstract 1188: Reversing epigenetic gene silencing to overcome immune evasion in CNS malignancies
Nivedita M. Ratnam, H. Sonnemann, M. Gilbert, Amber J. Giles
2019Tumor Biology0 citations Open access
Semantic Scholar
EXTH-63. EFFICIENT ADCC-MEDIATED KILLING OF MALIGNANT MENINGIOMA CELLS USING AVELUMAB AND AN ENGINEERED HIGH AVIDITY NATURAL KILLER CELL LINE, haNK
Amber J. Giles, Shu-Yu Hao, R. Fuji, M. Padget +14 more
2018Neuro-Oncology0 citations Open access
Semantic Scholar
Abstract A11: Ipilimumab protects T cells from the antiproliferative effects of dexamethasone
Amber J. Giles, Marsha-Kay N. D. Hutchinson, H. Sonnemann, Caitlin M. Reid +8 more
2018Checkpoints and Immunomodulation0 citations
Semantic Scholar
IMMU-68. SINGLE-CELL PROTEOMIC ANALYSIS OF IMMUNE CELL RESPONSE TO CHECKPOINT BLOCKADE USING 30-PARAMETER FLOW CYTOMETRY
Amber J. Giles, Leonard Nettey, T. Liechti, M. Beddall +14 more
2018Neuro-Oncology0 citations Open access
Semantic Scholar
INNV-38. THE NEURO-ONCOLOGY BRANCH TRANSLATIONAL RESEARCH IMMERSION PROGRAM: RESULTS FROM TWO YEARS OF DEVELOPMENT AND PARTICIPANT FEEDBACK
Amber J. Giles, Amélie Vézina, A. Acquaye, María Fletcher Ruiz +8 more
2018Neuro-Oncology0 citations Open access
Semantic Scholar
TMIC-01. ALERTING THE IMMUNE SYSTEM BY REMOVING EPIGENETIC SILENCING OF TH1 CHEMOKINES
H. Sonnemann, Amber J. Giles, Jinkyu Jung, Caitlin M. Reid +3 more
20170 citations Open access
Semantic Scholar
IMMU-53. CO-ADMINISTRATION OF DEXAMETHASONE WITH CHECKPOINT BLOCKADE THERAPY INCREASES SURVIVAL IN BRAIN TUMOR MODEL
Marsha-Kay N. D. Hutchinson, Amber J. Giles, H. Sonnemann, Caitlin M. Reid +2 more
20170 citations Open access
Semantic Scholar
CBIO-01. TRANSCRIPTIONAL MODULATION OF BRACHYURY IN CHORDOMA
Ashlee N. Seldomridge, H. Sonnemann, Jinkyu Jung, Amber J. Giles +6 more
20170 citations Open access
Semantic Scholar
Abstract 1533: Transcriptional inhibition of brachyury in chordoma is associated with adoption of quiescent phenotype
Ashlee N. Seldomridge, Jinkyu Jung, H. Sonnemann, Amber J. Giles +4 more
20170 citations
Semantic Scholar
Abstract 569: Dexamethasone inhibits T-cell proliferation through a CTLA-4 mediated pathway
Marsha-Kay N. D. Hutchinson, Amber J. Giles, H. Sonnemann, Caitlin M. Reid +2 more
20170 citations
Semantic Scholar
Abstract 3998: Alerting the immune system by removing epigenetic silencing of Th1 chemokines
H. Sonnemann, Amber J. Giles, Caitlin M. Reid, Marsha-Kay N. D. Hutchinson +2 more
20170 citations
Semantic Scholar
Abstract 5139: Adjuvant immunotherapy targeting CSF1R to limit metastatic progression
J. Evans, Amber J. Giles, Meera Murgai, M. Kasai +2 more
20160 citations
Semantic Scholar
IMST-13. DEXAMETHASONE ENHANCES CTLA-4 EXPRESSION DURING T CELL ACTIVATION
Amber J. Giles, Caitlin M. Reid, Marsha-Kay N. D. Hutchinson, Vinh Au +3 more
20160 citations Open access
Semantic Scholar
Abstract 4725: Hematopoietic stem cell niche activation and progenitor mobilization mediate cancer-associated immunosuppression and metastasis
Amber J. Giles, Meera Murgai, Y. Vicioso, S. Highfill +6 more
20150 citations
Semantic Scholar
Abstract 2074: Metastasis prevention using fibroblast activation protein-targeting prodrugs at the pre-metastatic niche
Meera Murgai, Amber J. Giles, M. Kasai, Y. Vicioso +2 more
20140 citations
Semantic Scholar
Abstract 3058: Bone marrow hematopoietic stem cell niche activation and mobilization fosters the metastatic niche
Amber J. Giles, Meera Murgai, Y. Vicioso, Steven Highfil +4 more
20140 citations
Semantic Scholar
Abstract 4585: Breaking metastatic dormancy during surgical resection of a primary tumor and implications for treatment strategies.
S. Granitto, Amber J. Giles, S. Lavotshkin, D. Rutigliano +2 more
20130 citations
Semantic Scholar
ShcA and c-Abl provide a new signaling axis regulating beta-selection (63.8)
P. Trampont, Li Zhang, Amber J. Giles, Scott F. Walk +2 more
2012Journal of Immunology0 citations
Semantic Scholar

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M. Gilbert — researcher profile on SciRah
Deric M. Park×20
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Jinkyu Jung×11

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