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Jin-Yun Liu · SciRah

Researcher profile · Semantic Scholar

Jin-Yun Liu

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Jin-Yun Liu — researcher profile on SciRah

h-index: 18
Works: 37
Citations: 2,338

Most-cited papers

Systemic depletion of serum l-Cyst(e)ine with an engineered human enzyme induces production of reactive oxygen species and suppresses tumor growth in mice
Shira L. Cramer, Achinto Saha, Jin-Yun Liu, Surendar Tadi +12 more
2016Nature Medicine488 citations Open access
Semantic Scholar
Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukemia
Wan Zhang, D. Trachootham, Jin-Yun Liu, Gang Chen +8 more
2012Nature Cell Biology357 citations Open access
Semantic Scholar
xCT: A Critical Molecule That Links Cancer Metabolism to Redox Signaling.
Jin-Yun Liu, X. Xia, Peng Huang
2020Molecular Therapy328 citations Open access
Semantic Scholar
Delivery of mRNA vaccine with a lipid-like material potentiates antitumor efficacy through Toll-like receptor 4 signaling
Hongxia Zhang, Xinru You, Xiaojuan Wang, Lei Cui +9 more
2021Proceedings of the National Academy of Sciences of the United States of America237 citations Open access
Semantic Scholar
Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia
W. Fiskus, N. Saba, M. Shen, M. Ghias +13 more
2014Cancer Research215 citations Open access
Semantic Scholar
Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential
H. Pelicano, Wan Zhang, Jin-Yun Liu, N. Hammoudi +4 more
2014Breast Cancer Research206 citations Open access
Semantic Scholar
Elimination of Chronic Lymphocytic Leukemia Cells in Stromal Microenvironment by Targeting CPT with an Anti-Angina Drug Perhexiline
Pan-Pan Liu, Jin-Yun Liu, Wen-Qi Jiang, J. Carew +7 more
2016Oncogene84 citations Open access
Semantic Scholar
Loss of p53 and altered miR15-a/16-1→MCL-1 pathway in CLL: insights from TCL1-Tg:p53−/− mouse model and primary human leukemia cells
Jin-Yun Liu, Gang Chen, Li Feng, Wan Zhang +8 more
2013Leukemia51 citations Open access
Semantic Scholar
Metabolic activation of mitochondria in glioma stem cells promotes cancer development through a reactive oxygen species-mediated mechanism
Shu-Qiang Yuan, Yun-Xin Lu, Jing Yang, Gang Chen +13 more
2015Stem cell research & therapeutics49 citations Open access
Semantic Scholar
Novel combination of histone methylation modulators with therapeutic synergy against acute myeloid leukemia in vitro and in vivo.
S. Wen, Jiankang Wang, Pan-Pan Liu, Yi-Qing Li +5 more
2018Cancer Letters41 citations
Semantic Scholar
Smad4 Deficiency Promotes Pancreatic Cancer Immunogenicity by Activating the Cancer‐Autonomous DNA‐Sensing Signaling Axis
W. Xiong, Wen-Zhuo He, Tian-tian Wang, Shuai He +20 more
2022Advancement of science35 citations Open access
Semantic Scholar
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity
Zi-Ning Wang, Feifei Xu, Jie Hu, Hongxia Zhang +14 more
2021Journal for ImmunoTherapy of Cancer31 citations Open access
Semantic Scholar
Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity
Lei Cui, Zi-Ning Wang, Zixuan Guo, Hongxia Zhang +16 more
2025Advancement of science28 citations Open access
Semantic Scholar
Detoxication of sulfur half-mustards by nucleophilic scavengers: robust activity of thiopurines
Jin-Yun Liu, K. Powell, H. Thames, M. C. Macleod
2010Chemical Research in Toxicology27 citations Open access
Semantic Scholar
Cancer cell-intrinsic biosynthesis of itaconate promotes tumor immunogenicity
Zi-Ning Wang, Lei Cui, Yanxun Lin, Bi-Tao Huo +12 more
2024EMBO Journal24 citations Open access
Semantic Scholar
Targeting p53-deficient chronic lymphocytic leukemia cells in vitro and in vivo by ROS-mediated mechanism
Jin-Yun Liu, Gang Chen, H. Pelicano, J. Liao +4 more
2016OncoTarget23 citations Open access
Semantic Scholar
Mevalonate Blockade in Cancer Cells Triggers CLEC9A+ Dendritic Cell-Mediated Antitumor Immunity
Feifei Xu, Zi-Ning Wang, Hongxia Zhang, Jiemin Chen +10 more
2021Cancer Research22 citations
Semantic Scholar
Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity.
Yongxiang Liu, Zifeng Wang, Huan Jin, Lei Cui +18 more
2024Cell Reports20 citations Open access
Semantic Scholar
The rheumatoid arthritis drug auranofin exerts potent anti-lymphoma effect by stimulating TXNRD-mediated ROS generation and inhibition of energy metabolism
Mengqi Yang, Jia-Xin Liu, Jia-nan Li, Shi-Jun Wen +5 more
2024Redox Biology18 citations Open access
Semantic Scholar
Alterations of mitochondrial biogenesis in chronic lymphocytic leukemia cells with loss of p53
Marcia A. Ogasawara, Jin-Yun Liu, H. Pelicano, N. Hammoudi +3 more
2016Mitochondrion (Amsterdam. Print)14 citations Open access
Semantic Scholar
SQLE-catalyzed squalene metabolism promotes mitochondrial biogenesis and tumor development in K-ras-driven cancer.
Junchen Pan, Rui Liu, Wen-Hua Lu, Hong Peng +15 more
2025Cancer Letters10 citations
Semantic Scholar
CBX2 suppresses interferon signaling to diminish tumor immunogenicity via a noncanonical corepressor complex
Yanxun Lin, Huan Jin, Yong She, Yiqun Zhang +20 more
2025Proceedings of the National Academy of Sciences of the United States of America8 citations Open access
Semantic Scholar
NRIP3 upregulation confers resistance to chemoradiotherapy in ESCC via RTF2 removal by accelerating ubiquitination and degradation of RTF2
Da-Qin Suo, Ling Wang, T. Zeng, Hui Zhang +5 more
2020Oncogenesis8 citations Open access
Semantic Scholar
Low-Temperature Polymorphic Transformation of β-Lactam Antibiotics
Hongyuan Luo, Jin-Yun Liu, Xiao He, Jin-Jin Li
2019Crystals6 citations Open access
Semantic Scholar
Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism
Mengyun Li, Huan Jin, Yongxiang Liu, Zi-Ning Wang +12 more
2025bioRxiv5 citations Open access
Semantic Scholar
Malignant transformation by oncogenic K‐ras requires IDH2‐mediated reductive carboxylation to promote glutamine utilization
Rui-Qi Liu, Pan-Pan Liu, Hui-Chang Bi, J. Ling +6 more
2022Cancer Communications4 citations Open access
Semantic Scholar
Development of a Human Therapeutic L-Cyst(e)Ine-Degrading Enzyme for the Treatment of Hematological Malignancies
Giulia Agnello, S. Alters, J. Tyler, Jin-Yun Liu +5 more
20161 citations
Semantic Scholar
Abstract 3073: Targeting chronic lymphocytic leukemia by interfering glutathione synthesis using a novel therapeutic enzyme cyst(e)inase (AEB3103)
Jin-Yun Liu, Li Feng, Everett M. Stone, J. Tyler +3 more
20161 citations
Semantic Scholar
Abstract 4560: Targeting chronic lymphocytic leukemia with p53 deficiency with phenethyl isothiocyanate
Jin-Yun Liu, Gang Chen, H. Pelicano
20151 citations
Semantic Scholar
Abstract LB-106: A novel TCL1-Tg:p53−/− mouse model of human CLL
Jin-Yun Liu, Gang Chen, Li Feng, Wan Zhang +6 more
20121 citations
Semantic Scholar
Effective Elimination of Lymphoma Cells in Stromal Microenvironment by Double Impact on ROS and ATP Metabolism Using Auranofin
Mengqi Yang, Pan-Pan Liu, Huanting Chen, Jing Yang +9 more
20200 citations Open access
Semantic Scholar
システイナーゼ/シスチナーゼによるL‐システイン/シスチンの全身的枯渇は活性酸素種を増加させて腫瘍の増殖を抑制する
L. CramerShira, Triplett Kendra, L. Candice, Grinson George +12 more
20170 citations
Semantic Scholar
Abstract 2697: A novel therapeutic strategy to effectively kill CLL cells in stromal microenvironment by targeting lipid metabolism
Pan-Pan Liu, Jin-Yun Liu, Marcia A. Ogasawara, H. Pelicano +3 more
20140 citations
Semantic Scholar
Therapeutics , Targets , and Chemical Biology Aurano fi n Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia
W. Fiskus, N. Saba, M. Shen, M. Ghias +13 more
20140 citations
Semantic Scholar
Abstract 3072: Characterization of TCL1-Tg:p53-/- mice that resemble human chronic lymphocytic leukemia with 17p-deletion: alterations in p53→Mir30→EZH2 axis.
Jin-Yun Liu, Marcia A. Ogasawara, Gang Chen, H. Pelicano +1 more
20130 citations
Semantic Scholar
CHARACTERIZATION OF TCL1-Tg:P53-/- MICE THAT RESEMBLE HUMAN CHRONIC LYMPHOCYTIC LEUKEMIA WITH 17P-DELETION
Jin-Yun Liu
20130 citations
Semantic Scholar
Abstract 1541: Role of GSH in mediating stromal-leukemia interaction and promoting cell survival and drug resistance in chronic lymphocytic leukemia
Wan Zhang, D. Trachootham, Jin-Yun Liu, M. Keating +1 more
20100 citations
Semantic Scholar

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