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P. Tofilon · SciRah

Researcher profile · Semantic Scholar

P. Tofilon

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P. Tofilon — researcher profile on SciRah

h-index: 55
Works: 283
Citations: 9,987

Most-cited papers

Ionizing radiation and glioblastoma exosomes: implications in tumor biology and cell migration.
W. Arscott, A. Tandle, Shu-Ping Zhao, J. Shabason +5 more
2013Translational Oncology220 citations Open access
Semantic Scholar
A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid For Patients With Glioblastoma
A. Krauze, S. Myrehaug, Michael G. Chang, Diane J Holdford +5 more
2015International Journal of Radiation Oncology, Biology, Physics191 citations Open access
Semantic Scholar
The brain microenvironment preferentially enhances the radioresistance of CD133(+) glioblastoma stem-like cells.
Muhammad Jamal, Barbara Rath, P. Tsang, K. Camphausen +1 more
2012Neoplasia141 citations Open access
Semantic Scholar
Astrocytes Enhance the Invasion Potential of Glioblastoma Stem-Like Cells
Barbara Rath, Joshlean Fair, Muhammad Jamal, K. Camphausen +1 more
2013PLoS ONE117 citations Open access
Semantic Scholar
The DNA-PK Inhibitor VX-984 Enhances the Radiosensitivity of Glioblastoma Cells Grown In Vitro and as Orthotopic Xenografts
Cindy R. Timme, Barbara Rath, J. O'Neill, K. Camphausen +1 more
2018Molecular Cancer Therapeutics97 citations Open access
Semantic Scholar
Post-radiation increase in VEGF enhances glioma cell motility in vitro
W. Kil, P. Tofilon, K. Camphausen
2012Radiation Oncology87 citations Open access
Semantic Scholar
Grand rounds at the National Institutes of Health: HDAC inhibitors as radiation modifiers, from bench to clinic
J. Shabason, P. Tofilon, K. Camphausen
2011Journal of Cellular and Molecular Medicine84 citations Open access
Semantic Scholar
The mTORC1/mTORC2 Inhibitor AZD2014 Enhances the Radiosensitivity of Glioblastoma Stem-like Cells
J. Kahn, T. Hayman, K. Camphausen, P. Tofilon
201281 citations Open access
Semantic Scholar
FOXM1 and STAT3 interaction confers radioresistance in glioblastoma cells
U. Maachani, U. Shankavaram, Tamalee R. Kramp, P. Tofilon +2 more
2016OncoTarget73 citations Open access
Semantic Scholar
4E-BP1 is a tumor suppressor protein reactivated by mTOR inhibition in head and neck cancer
Zhi-Yong Wang, Xiao-Dong Feng, A. Molinolo, Daniel Martin +16 more
2019Cancer Research71 citations Open access
Semantic Scholar
Preclinical models in radiation oncology
J. Kahn, P. Tofilon, K. Camphausen
2012Radiation Oncology56 citations Open access
Semantic Scholar
Inhibition of PLK1 in glioblastoma multiforme induces mitotic catastrophe and enhances radiosensitization
A. Tandle, Tamalee R. Kramp, W. Kil, A. Halthore +5 more
2013European Journal of Cancer54 citations Open access
Semantic Scholar
The ATP-Competitive mTOR Inhibitor INK128 enhances in vitro and in vivo radiosensitivity of pancreatic carcinoma cells
T. Hayman, Amy Wahba, Barbara Rath, Heekyong R. Bae +4 more
2013Clinical Cancer Research52 citations Open access
Semantic Scholar
Coculture with astrocytes reduces the radiosensitivity of glioblastoma stem-like cells and identifies additional targets for radiosensitization
Barbara Rath, Amy Wahba, K. Camphausen, P. Tofilon
2015Cancer Medicine47 citations Open access
Semantic Scholar
Translation initiation factor eIF4E is a target for tumor cell radiosensitization
T. Hayman, E. Williams, Muhammad Jamal, U. Shankavaram +2 more
2012Cancer Research44 citations Open access
Semantic Scholar
The XPO1 inhibitor Selinexor inhibits translation and enhances the radiosensitivity of glioblastoma cells grown in vitro and in vivo
Amy Wahba, Barbara Rath, J. O'Neill, K. Camphausen +1 more
2018Molecular Cancer Therapeutics39 citations Open access
Semantic Scholar
Salen Mn Complexes are Superoxide Dismutase/Catalase Mimetics that Protect the Mitochondria
S. Doctrow, M. Liesa, S. Melov, O. Shirihai +1 more
201236 citations
Semantic Scholar
Inhibition of the histone H3K27 demethylase UTX enhances tumor cell radiosensitivity
Barbara Rath, Isabella Waung, K. Camphausen, P. Tofilon
2018Molecular Cancer Therapeutics35 citations Open access
Semantic Scholar
Polysome profiling links translational control to the radioresponse of glioblastoma stem-like cells
Amy Wahba, Barbara Rath, K. Bisht, K. Camphausen +1 more
2016Cancer Research24 citations Open access
Semantic Scholar
Molecular Profiling Indicates Orthotopic Xenograft of Glioma Cell Lines Simulate a Subclass of Human Glioblastoma
U. Shankavaram, M. Bredel, W. Burgan, D. Carter +2 more
2012Journal of Cellular and Molecular Medicine22 citations Open access
Semantic Scholar
The mTORC1/mTORC2 inhibitor AZD2014 enhances the radiosensitivity of glioblastoma stem-like cells.
Jenna M. Kahn, T. Hayman, M. Jamal, Barbara Rath +3 more
2014Neuro-Oncology20 citations Open access
Semantic Scholar
Radiosensitizers in the temozolomide era for newly diagnosed glioblastoma.
P. Mathen, L. Rowe, M. Mackey, D. Smart +2 more
2019Neuro-Oncology Practice18 citations Open access
Semantic Scholar
Late toxicity in long-term survivors from a phase 2 study of concurrent radiation therapy, temozolomide and valproic acid for newly diagnosed glioblastoma.
A. Krauze, M. Mackey, L. Rowe, Michael G. Chang +5 more
2018Neuro-Oncology Practice17 citations Open access
Semantic Scholar
Radiation-induced translational control of gene expression
Amy Wahba, Stacey L. Lehman, P. Tofilon
2017Translation16 citations Open access
Semantic Scholar
Improving Radiation Response in Glioblastoma Using ECO/siRNA Nanoparticles Targeting DNA Damage Repair
Jennifer A. Lee, N. Ayat, Zhanhu Sun, P. Tofilon +2 more
2020Cancers15 citations Open access
Semantic Scholar
Radiation drives the evolution of orthotopic xenografts initiated from glioblastoma stem-like cells
Joseph H. McAbee, Barbara Rath, Kristin Valdez, Dejauwne L. Young +4 more
2019Cancer Research15 citations Open access
Semantic Scholar
The Quiescent Metabolic Phenotype of Glioma Stem Cells
Elizabeth I. Spehalski, Jennifer A. Lee, C. Peters, P. Tofilon +1 more
2019Journal of Proteomics & Bioinformatics14 citations Open access
Semantic Scholar
Competitive but Not Allosteric mTOR Kinase Inhibition Enhances Tumor Cell Radiosensitivity.
T. Hayman, Tamalee R. Kramp, J. Kahn, Muhammad Jamal +2 more
2013Translational Oncology14 citations Open access
Semantic Scholar
Revisiting Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients with Glioblastoma—Proteomic Alteration and Comparison Analysis with the Standard-of-Care Chemoirradiation
A. Krauze, Yingdong Zhao, Ming-Chung Li, Joanna H. Shih +8 more
2023Biomolecules13 citations Open access
Semantic Scholar
Urinary Metabolomic Profiling of Patients with Glioblastoma Multiforme
T. AnitaT, Le, U. Shankavaram, Meredith V. Brown +7 more
201313 citations Open access
Semantic Scholar
Increasing the Therapeutic Ratio of Radiotherapy
P. Tofilon, K. Camphausen
201712 citations Open access
Semantic Scholar
MGMT inhibition regulates radioresponse in GBM, GSC, and melanoma
H. Yun, Tamalee R. Kramp, K. Palanichamy, P. Tofilon +1 more
2024Scientific Reports11 citations Open access
Semantic Scholar
Detection of glioblastoma intratumor heterogeneity in radiosensitivity using patient-derived neurosphere cultures
Joseph H. McAbee, Charlotte Degorre-Kerbaul, Kristin Valdez, A. Wendler +4 more
2020Journal of Neuro-Oncology11 citations Open access
Semantic Scholar
Radiation-induced alternative transcripts as detected in total and polysome-bound mRNA
Amy Wahba, Michael C. Ryan, U. Shankavaram, K. Camphausen +1 more
2017OncoTarget11 citations Open access
Semantic Scholar
CX-5461 induces radiosensitization through modification of the DNA damage response and not inhibition of RNA polymerase I
Stacey L. Lehman, Kayla Schwartz, S. Maheshwari, K. Camphausen +1 more
2022Scientific Reports10 citations Open access
Semantic Scholar
The Radiosensitizing Effect of AZD0530 in Glioblastoma and Glioblastoma Stem-like Cells
H. Yun, Jennifer A. Lee, W. Kil, Tamalee R. Kramp +2 more
2021Molecular Cancer Therapeutics10 citations Open access
Semantic Scholar
Detection of metabolic change in glioblastoma cells after radiotherapy using hyperpolarized 13C‐MRI
T. Kawai, J. Brender, Jennifer A. Lee, Tamalee R. Kramp +4 more
2021NMR in Biomedicine8 citations Open access
Semantic Scholar
Translation Initiation Machinery as a Tumor Selective Target for Radiosensitization
Stacey L. Lehman, E. Wilson, K. Camphausen, P. Tofilon
2021International Journal of Molecular Sciences8 citations Open access
Semantic Scholar
Bench to bedside radiosensitizer development strategy for newly diagnosed glioblastoma
Charlotte Degorre, P. Tofilon, K. Camphausen, P. Mathen
2021Radiation Oncology8 citations Open access
Semantic Scholar
Glioblastoma radiosensitization by pimozide
Barbara Rath, K. Camphausen, P. Tofilon
2016Translational Cancer Research8 citations Open access
Semantic Scholar
Inhibition of the translation initiation factor eIF4A enhances tumor cell radiosensitivity
Stacey L. Lehman, Theresa Wechsler, Kayla Schwartz, L. Brown +6 more
2022Molecular Cancer Therapeutics7 citations Open access
Semantic Scholar
The Olfactory Bulb Provides a Radioresistant Niche for Glioblastoma Cells
Cindy R. Timme, Charlotte Degorre-Kerbaul, Joseph H. McAbee, Barbara Rath +3 more
2020International Journal of Radiation Oncology, Biology, Physics5 citations Open access
Semantic Scholar
Radiosensitization Effects of Novel Triple-Inhibitor CUDC-101 in Glioblastoma Multiforme and Breast Cancer Cells In Vitro
C. Schlaff, W. Arscott, I. Gordon, A. Tandle +2 more
20134 citations Open access
Semantic Scholar
Radiosensitization by the novel DNA intercalating agent vosaroxin
I. Gordon, Christian A. Graves, W. Kil, Tamalee R. Kramp +2 more
2012Radiation Oncology4 citations Open access
Semantic Scholar
Targeting PRMT5 enhances the radiosensitivity of tumor cells grown in vitro and in vivo
Charlotte Degorre, Steven Lohard, Christina N. Bobrek, Komal Rawal +2 more
2024Scientific Reports3 citations Open access
Semantic Scholar
Glioblastoma cells have increased capacity to repair radiation-induced DNA damage after migration to the olfactory bulb
Charlotte Degorre, Ian C. Sutton, Stacey L. Lehman, U. Shankavaram +2 more
2022Cancer Cell International3 citations Open access
Semantic Scholar
Distinctions Between the Metabolic Changes in Glioblastoma Cells and Glioma Stem-like Cells Following Irradiation
E. I. Spehalski, C. Peters, K. Camphausen, P. Tofilon
20173 citations Open access
Semantic Scholar
Glioblastoma Cells Induce Neuron Loss In Vivo and In Vitro
Komal Rawal, Charlotte Degorre, P. Tofilon
2025Cancers2 citations Open access
Semantic Scholar
Loss of CARM1 alters the developmental programming of Glioma stem-like cells and creates a druggable NGFR/NTRK dependency
Dejauwne L. Young, J. Aguilan, Ronald Cutler, Stephanie Stransky +10 more
2025bioRxiv2 citations Open access
Semantic Scholar
International Migration of Highly Qualified Housewife Mothers and Their Career Concerns
A. Şahin, S. Aytaç, P. Tofilon, K. Camphausen
20212 citations Open access
Semantic Scholar

Frequent co-authors

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K. Camphausen×42
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K. Camphausen — researcher profile on SciRah
Barbara Rath×12
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Barbara Rath — researcher profile on SciRah
U. Shankavaram×12
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U. Shankavaram — researcher profile on SciRah
Tamalee R. Kramp×9
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Tamalee R. Kramp — researcher profile on SciRah

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Amy Wahba — researcher profile on SciRah

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T. Hayman — researcher profile on SciRah

Stacey L. Lehman×5

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Stacey L. Lehman — researcher profile on SciRah

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A. Tandle — researcher profile on SciRah

Muhammad Jamal×4

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Muhammad Jamal — researcher profile on SciRah

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W. Kil — researcher profile on SciRah

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Jennifer A. Lee — researcher profile on SciRah

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Charlotte Degorre — researcher profile on SciRah