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A. Luk · SciRah

Researcher profile · Semantic Scholar

A. Luk

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A. Luk — researcher profile on SciRah

h-index: 41
Works: 193
Citations: 8,525

Most-cited papers

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
A. Mahajan, C. Spracklen, Wei-Hua Zhang, M. Ng +345 more
2022Nature Genetics616 citations Open access
Semantic Scholar
The Case for Early Identification and Intervention of Chronic Kidney Disease: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Michael G. Shlipak, S. Tummalapalli, L. Boulware, Morgan E. Grams +48 more
2020Kidney International552 citations Open access
Semantic Scholar
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
Ken Suzuki, K. Hatzikotoulas, L. Southam, H. Taylor +360 more
2024Nature540 citations Open access
Semantic Scholar
Impact of age at type 2 diabetes mellitus diagnosis on mortality and vascular complications: systematic review and meta-analyses
N. Nanayakkara, A. Curtis, S. Heritier, A. Gadowski +18 more
2020Diabetologia336 citations Open access
Semantic Scholar
Integrated image-based deep learning and language models for primary diabetes care
Jiajia Li, Z. Guan, Jing Wang, C. Y. Cheung +89 more
2024Nature Medicine263 citations Open access
Semantic Scholar
Diabetes and infection: review of the epidemiology, mechanisms and principles of treatment
R. Holt, C. Cockram, R. Ma, A. Luk
2024Diabetologia252 citations Open access
Semantic Scholar
Trends in the incidence of diagnosed diabetes: a multicountry analysis of aggregate data from 22 million diagnoses in high-income and middle-income settings
D. Magliano, Lei Chen, R. Islam, B. Carstensen +41 more
2021The Lancet Diabetes and Endocrinology146 citations Open access
Semantic Scholar
Worldwide estimates of incidence of type 2 diabetes in children and adolescents in 2021.
Hong-Jiang Wu, C. Patterson, Xinge Zhang, Ruhina Binta A. Ghani +4 more
2022Diabetes Research and Clinical Practice145 citations Open access
Semantic Scholar
Secular trends in all-cause and cause-specific mortality rates in people with diabetes in Hong Kong, 2001–2016: a retrospective cohort study
Hong-Jiang Wu, E. Lau, R. Ma, A. Kong +6 more
2020Diabetologia104 citations Open access
Semantic Scholar
Secular trends in incidence of type 1 and type 2 diabetes in Hong Kong: A retrospective cohort study
A. Luk, Calvin Ke, E. Lau, Hong-Jiang Wu +6 more
2020PLoS Medicine74 citations Open access
Semantic Scholar
Trends in all-cause mortality among people with diagnosed diabetes in high-income settings: a multicountry analysis of aggregate data
D. Magliano, Lei Chen, B. Carstensen, E. Gregg +31 more
2022The Lancet Diabetes and Endocrinology71 citations Open access
Semantic Scholar
Age at diagnosis, glycemic trajectories, and responses to oral glucose-lowering drugs in type 2 diabetes in Hong Kong: A population-based observational study
Calvin Ke, T. Stukel, B. Shah, E. Lau +6 more
2020PLoS Medicine56 citations Open access
Semantic Scholar
Shortened Relative Leukocyte Telomere Length Is Associated With Prevalent and Incident Cardiovascular Complications in Type 2 Diabetes: Analysis From the Hong Kong Diabetes Register
Feifei Cheng, A. Luk, C. Tam, B. Fan +15 more
2020Diabetes Care55 citations Open access
Semantic Scholar
Nonalbuminuric Diabetic Kidney Disease and Risk of All-Cause Mortality and Cardiovascular and Kidney Outcomes in Type 2 Diabetes: Findings From the Hong Kong Diabetes Biobank.
Qiao Jin, A. Luk, E. Lau, C. Tam +30 more
2022American Journal of Kidney Diseases51 citations Open access
Semantic Scholar
Clinical outcomes following discontinuation of renin-angiotensin-system inhibitors in patients with type 2 diabetes and advanced chronic kidney disease: A prospective cohort study
A. Yang, M. Shi, E. Lau, Hong-Jiang Wu +7 more
2022EClinicalMedicine50 citations Open access
Semantic Scholar
Young age at diabetes diagnosis amplifies the effect of diabetes duration on risk of chronic kidney disease: a prospective cohort study
Hong-Jiang Wu, E. Lau, A. Yang, B. Fan +6 more
2021Diabetologia49 citations Open access
Semantic Scholar
Glucose-lowering drug use, glycemic outcomes, and severe hypoglycemia: 18-Year trends in 0·9 million adults with Diabetes in Hong Kong (2002–2019)
A. Yang, Hong-Jiang Wu, E. Lau, Xinge Zhang +7 more
2022The Lancet Regional Health - Western Pacific40 citations Open access
Semantic Scholar
A novel electronic health record-based, machine-learning model to predict severe hypoglycemia leading to hospitalizations in older adults with diabetes: A territory-wide cohort and modeling study
M. Shi, A. Yang, E. Lau, A. Luk +6 more
2024PLoS Medicine38 citations Open access
Semantic Scholar
Age-specific population attributable risk factors for all-cause and cause-specific mortality in type 2 diabetes: An analysis of a 6-year prospective cohort study of over 360,000 people in Hong Kong
Hong-Jiang Wu, E. Lau, A. Yang, Xinge Zhang +7 more
2023PLoS Medicine34 citations Open access
Semantic Scholar
A Single and Multiple Ascending Dose Study of Toll‐Like Receptor 7 Agonist (RO7020531) in Chinese Healthy Volunteers
A. Luk, Qiu-Di Jiang, Katerina Glavini, M. Triyatni +4 more
2020Clinical and Translational Science32 citations Open access
Semantic Scholar
Association of technologically assisted integrated care with clinical outcomes in type 2 diabetes in Hong Kong using the prospective JADE Program: A retrospective cohort analysis
L. Lim, E. Lau, R. Ozaki, Harriet Chung +25 more
2020PLoS Medicine32 citations Open access
Semantic Scholar
Development of genome-wide polygenic risk scores for lipid traits and clinical applications for dyslipidemia, subclinical atherosclerosis, and diabetes cardiovascular complications among East Asians
C. Tam, Cadmon K. P. Lim, A. Luk, A. C. Ng +37 more
2021Genome Medicine31 citations Open access
Semantic Scholar
Effect of a Web-Based Management Guide on Risk Factors in Patients With Type 2 Diabetes and Diabetic Kidney Disease
J. Chan, Y. Thewjitcharoen, Thy Khuê Nguyễn, A. Tan +20 more
2022JAMA Network Open30 citations Open access
Semantic Scholar
Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications
Ken Suzuki, K. Hatzikotoulas, L. Southam, H. Taylor +347 more
2023medRxiv27 citations Open access
Semantic Scholar
The role of age on the risk relationship between prediabetes and major morbidities and mortality: Analysis of the Hong Kong diabetes surveillance database of 2 million Chinese adults
Xinge Zhang, Hong-Jiang Wu, B. Fan, M. Shi +7 more
2022The Lancet Regional Health - Western Pacific26 citations Open access
Semantic Scholar
High-density lipoprotein subclasses and cardiovascular disease and mortality in type 2 diabetes: analysis from the Hong Kong Diabetes Biobank
Qiao Jin, E. Lau, A. Luk, Claudia H. T. Tam +35 more
2022Cardiovascular Diabetology24 citations Open access
Semantic Scholar
Relative leucocyte telomere length is associated with incident end-stage kidney disease and rapid decline of kidney function in type 2 diabetes: analysis from the Hong Kong Diabetes Register
Feifei Cheng, A. Luk, Hong-Jiang Wu, Claudia H. T. Tam +17 more
2021Diabetologia23 citations Open access
Semantic Scholar
Age- and sex-specific hospital bed-day rates in people with and without type 2 diabetes: A territory-wide population-based cohort study of 1.5 million people in Hong Kong
Hong-Jiang Wu, A. Yang, E. Lau, Xinge Zhang +9 more
2023PLoS Medicine22 citations Open access
Semantic Scholar
Glucose-lowering drugs and outcome from COVID-19 among patients with type 2 diabetes mellitus: a population-wide analysis in Hong Kong
A. Luk, T. Yip, Xinge Zhang, A. Kong +3 more
2021BMJ Open22 citations Open access
Semantic Scholar
Long-term metformin use and risk of pneumonia and related death in type 2 diabetes: a registry-based cohort study
A. Yang, Mai Shi, Hong-Jiang Wu, E. Lau +6 more
2021Diabetologia22 citations Open access
Semantic Scholar
Secular trends in rates of hospitalisation for lower extremity amputation and 1 year mortality in people with diabetes in Hong Kong, 2001–2016: a retrospective cohort study
Hong-Jiang Wu, A. Yang, E. Lau, R. Ma +5 more
2020Diabetologia22 citations Open access
Semantic Scholar
Type 2 diabetes pathway-specific polygenic risk scores elucidate heterogeneity in clinical presentation, disease progression and diabetic complications in 18,217 Chinese individuals with type 2 diabetes
Gechang Yu, C. Tam, Cadmon K. P. Lim, M. Shi +36 more
2024Diabetologia21 citations
Semantic Scholar
Circulating metabolomic markers linking diabetic kidney disease and incident cardiovascular disease in type 2 diabetes: analyses from the Hong Kong Diabetes Biobank
Qiao Jin, E. Lau, A. Luk, Claudia H. T. Tam +40 more
2024Diabetologia21 citations Open access
Semantic Scholar
Comparison of beta-cell function between Hong Kong Chinese with young-onset type 2 diabetes and late-onset type 2 diabetes.
Ying-Nan Fan, B. Fan, E. Lau, Cadmon K. P. Lim +7 more
2023Diabetes Research and Clinical Practice21 citations
Semantic Scholar
Detection of increased serum miR-122-5p and miR-455-3p levels before the clinical diagnosis of liver cancer in people with type 2 diabetes
Heung M. Lee, W. K. Wong, B. Fan, E. Lau +7 more
2021Scientific Reports21 citations Open access
Semantic Scholar
Evaluating the impact of glucokinase activation on risk of cardiovascular disease: a Mendelian randomisation analysis
Ke Wang, M. Shi, Chui-Guo Huang, B. Fan +5 more
2022Cardiovascular Diabetology20 citations Open access
Semantic Scholar
Major Adverse Cardiovascular Events and Mortality Prediction by Circulating GDF-15 in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Su-Yi Xie, Qi Li, A. Luk, H. Lan +4 more
2022Biomolecules19 citations Open access
Semantic Scholar
Lifetime risk of developing diabetes in Chinese people with normoglycemia or prediabetes: A modeling study
Xinge Zhang, Hong-Jiang Wu, B. Fan, M. Shi +7 more
2022PLoS Medicine19 citations Open access
Semantic Scholar
Data Resource Profile: The Hong Kong Diabetes Surveillance Database (HKDSD).
Hong-Jiang Wu, E. Lau, A. Yang, Xinge Zhang +6 more
2021International Journal of Epidemiology19 citations Open access
Semantic Scholar
Trends in kidney failure and kidney replacement therapy in people with diabetes in Hong Kong, 2002-2015: A retrospective cohort study
Hong-Jiang Wu, E. Lau, A. Yang, C. Szeto +6 more
2021The Lancet Regional Health - Western Pacific19 citations Open access
Semantic Scholar
Gender-associated cardiometabolic risk profiles and health behaviors in patients with type 2 diabetes: a cross-sectional analysis of the Joint Asia Diabetes Evaluation (JADE) program
L. Lim, E. Lau, A. Kong, Amy W. C. Fu +18 more
2022The Lancet Regional Health - Western Pacific17 citations Open access
Semantic Scholar
Risk Associations of Glycemic Burden and Obesity With Liver Cancer—A 10‐Year Analysis of 15,280 Patients With Type 2 Diabetes
Dandan Mao, E. Lau, Hong-Jiang Wu, A. Yang +8 more
2022Hepatology Communications16 citations Open access
Semantic Scholar
Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients with Type 2 Diabetes.
G. Jiang, A. Luk, Claudia H. T. Tam, R. Ozaki +29 more
2022Diabetes15 citations Open access
Semantic Scholar
Skin autofluorescence is associated with higher risk of cardiovascular events in Chinese adults with type 2 diabetes: A prospective cohort study from the Hong Kong Diabetes Biobank.
Qiao Jin, E. Lau, A. Luk, R. Ozaki +10 more
2021Journal of diabetes and its complications15 citations
Semantic Scholar
NT-proBNP improves prediction of cardiorenal complications in type 2 diabetes: the Hong Kong Diabetes Biobank
R. Ma, C. Tam, Yong Hou, E. Lau +11 more
2024Diabetologia14 citations Open access
Semantic Scholar
Impact of Body Composition and Anemia on Accuracy of a Real-Time Continuous Glucose Monitor in Diabetes Patients on Continuous Ambulatory Peritoneal Dialysis
J. Ling, J. Ng, E. Lau, A. Luk +6 more
2023Diabetes Technology & Therapeutics14 citations
Semantic Scholar
Incident cardiovascular-kidney disease, diabetic ketoacidosis, hypoglycaemia and mortality in adult-onset type 1 diabetes: a population-based retrospective cohort study in Hong Kong
Ying-Nan Fan, E. Lau, Hong-Jiang Wu, A. Yang +5 more
2023The Lancet Regional Health - Western Pacific14 citations Open access
Semantic Scholar
Attenuated Risk Association of End-Stage Kidney Disease with Metformin in Type 2 Diabetes with eGFR Categories 1–4
A. Yang, E. Lau, Hong-Jiang Wu, R. Ma +6 more
2022Pharmaceuticals14 citations Open access
Semantic Scholar
Shortened Relative Leukocyte Telomere Length is Associated with All-cause Mortality in Type 2 Diabetes- Analysis from the Hong Kong Diabetes Register.
Feifei Cheng, A. Luk, Hong-Jiang Wu, Cadmon Kp Lim +16 more
2021Diabetes Research and Clinical Practice13 citations
Semantic Scholar
Population-level productivity-adjusted life years lost in individuals with type 2 diabetes in Hong Kong: a life table modelling study
Hong-Jiang Wu, Haobin Zhou, Chuiguo Huang, A. Yang +10 more
2025The Lancet Regional Health - Western Pacific12 citations Open access
Semantic Scholar

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