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M. Fragai · SciRah

Researcher profile · Semantic Scholar

M. Fragai

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M. Fragai — researcher profile on SciRah

h-index: 37
Works: 219
Citations: 4,237

Most-cited papers

Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N6-Methyladenosine-Modified RNAs
Mariachiara Micaelli, Andrea Dalle Vedove, L. Cerofolini, Jacopo Vigna +17 more
2022ACS Pharmacology & Translational Science79 citations Open access
Semantic Scholar
The lipooligosaccharide of the gut symbiont Akkermansia muciniphila exhibits a remarkable structure and TLR signaling capacity
Pilar García-Vello, Hanne L. P. Tytgat, J. Elzinga, M. Van Hul +10 more
2024Nature Communications69 citations Open access
Semantic Scholar
Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein
J. Amato, L. Cerofolini, D. Brancaccio, S. Giuntini +10 more
2019Nucleic Acids Research59 citations Open access
Semantic Scholar
Cerebrospinal fluid lipoproteins inhibit α-synuclein aggregation by interacting with oligomeric species in seed amplification assays
G. Bellomo, Silvia Paciotti, L. Concha-Marambio, Domenico Rizzo +17 more
2023Molecular Neurodegeneration52 citations Open access
Semantic Scholar
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors.
L. Manzoni, C. Zucal, D. Di Maio, V. D'Agostino +15 more
2018Journal of Medicinal Chemistry50 citations Open access
Semantic Scholar
Dissecting the Interactions between Human Serum Albumin and α-Synuclein: New Insights on the Factors Influencing α-Synuclein Aggregation in Biological Fluids.
G. Bellomo, Sara Bologna, L. Cerofolini, Silvia Paciotti +5 more
2019Journal of Physical Chemistry B42 citations
Semantic Scholar
Mechanism and Inhibition of Matrix Metalloproteinases.
L. Cerofolini, M. Fragai, C. Luchinat
2019Current Medicinal Chemistry42 citations
Semantic Scholar
Therapeutic targeting of MMP-12 for the treatment of chronic obstructive pulmonary disease
C. Baggio, J. Velazquez, M. Fragai, T. Nordgren +1 more
2020Journal of Medicinal Chemistry41 citations Open access
Semantic Scholar
Unveiling protein dynamics in solution with field-cycling NMR relaxometry.
G. Parigi, E. Ravera, M. Fragai, C. Luchinat
2021Progress in nuclear magnetic resonance spectroscopy37 citations Open access
Semantic Scholar
Characterization of PEGylated Asparaginase: New Opportunities from NMR Analysis of Large PEGylated Therapeutics.
L. Cerofolini, S. Giuntini, A. Carlon, E. Ravera +4 more
2019Chemistry37 citations Open access
Semantic Scholar
Structural characterization of a protein adsorbed on aluminum hydroxide adjuvant in vaccine formulation
L. Cerofolini, S. Giuntini, E. Ravera, C. Luchinat +2 more
2019npj Vaccines34 citations Open access
Semantic Scholar
Interhelical interactions within the STIM1 CC1 domain modulate CRAC channel activation
P. Rathner, M. Fahrner, L. Cerofolini, H. Grabmayr +10 more
2020Nature Chemical Biology33 citations Open access
Semantic Scholar
Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils.
L. Cerofolini, E. Ravera, Sara Bologna, T. Wiglenda +11 more
2020Chemical Communications32 citations Open access
Semantic Scholar
HuR-targeted agents: an insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models.
Giulia Assoni, V. La Pietra, Rosangela Digilio, Caterina Ciani +14 more
2021Advanced Drug Delivery Reviews29 citations Open access
Semantic Scholar
Integrative Approaches in Structural Biology: A More Complete Picture from the Combination of Individual Techniques
L. Cerofolini, M. Fragai, E. Ravera, C. A. Diebolder +2 more
2019Biomolecules26 citations Open access
Semantic Scholar
Monoclonal antibodies protect against pandrug-resistant Klebsiella pneumoniae
Emanuele Roscioli, Vittoria Zucconi Galli Fonseca, Soraya Soledad Bosch, Ida Paciello +28 more
2025Nature24 citations Open access
Semantic Scholar
Seed amplification assays for diagnosing synucleinopathies: the issue of influencing factors.
G. Bellomo, Silvia Paciotti, Leonardo Gatticchi, Domenico Rizzo +3 more
2021Frontiers in Bioscience23 citations Open access
Semantic Scholar
1H NMR Relaxometric Study of Chitosan-Based Nanogels Containing Mono- and Bis-Hydrated Gd(III) Chelates: Clues for MRI Probes of Improved Sensitivity.
F. Carniato, L. Tei, M. Botta, E. Ravera +3 more
2020ACS Applied Bio Materials22 citations Open access
Semantic Scholar
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme.
S. Daniele, V. La Pietra, Rebecca Piccarducci, D. Pietrobono +16 more
2021European Journal of Pharmacology21 citations Open access
Semantic Scholar
A Structurally Simple Vaccine Candidate Reduces Progression and Dissemination of Triple-Negative Breast Cancer
A. Amedei, Fatemeh Asadzadeh, F. Papi, M. Vannucchi +21 more
2020iScience20 citations Open access
Semantic Scholar
HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes.
C. Baggio, L. Cerofolini, M. Fragai, C. Luchinat +1 more
2018ACS Medicinal Chemistry Letters20 citations Open access
Semantic Scholar
A high-resolution view of the coordination environment in a paramagnetic metalloprotein from its magnetic properties.
E. Ravera, L. Gigli, E. Suturina, V. Calderone +3 more
2021Angewandte Chemie18 citations Open access
Semantic Scholar
Relaxivity of Gd-based MRI contrast agents in crosslinked hyaluronic acid as a model for tissues.
M. Fragai, E. Ravera, F. Tedoldi, C. Luchinat +1 more
2019ChemPhysChem18 citations
Semantic Scholar
How Do Nuclei Couple to the Magnetic Moment of a Paramagnetic Center? A New Theory at the Gauntlet of the Experiments.
L. Cerofolini, J. Silva, E. Ravera, M. Romanelli +5 more
2019Journal of Physical Chemistry Letters17 citations
Semantic Scholar
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors.
Pasquale Russomanno, Giulia Assoni, J. Amato, Vincenzo Maria D'amore +20 more
2021Journal of Medicinal Chemistry16 citations Open access
Semantic Scholar
A New NT4 Peptide-Based Drug Delivery System for Cancer Treatment
J. Brunetti, Sara Piantini, M. Fragai, S. Scali +6 more
2020Molecules16 citations Open access
Semantic Scholar
Protein Glycosylation through Sulfur Fluoride Exchange (SuFEx) Chemistry: The Key Role of a Fluorosulfate Thiolactoside.
A. Marra, Jia-Jia Dong, Tiancheng Ma, S. Giuntini +7 more
2018Chemistry16 citations
Semantic Scholar
NMR quality control of fragment libraries for screening
S. Sreeramulu, C. Richter, Till Kuehn, Kamal Azzaoui +11 more
2020Journal of Biomolecular NMR14 citations Open access
Semantic Scholar
Orientation of immobilized antigens on common surfaces by a simple computational model: Exposition of SARS-CoV-2 Spike protein RBD epitopes
L. Cerofolini, M. Fragai, C. Luchinat, E. Ravera
2020Biophysical Chemistry14 citations Open access
Semantic Scholar
SARS-CoV-2 Mpro inhibition by a zinc ion: structural features and hints for drug design.
Deborah Grifagni, V. Calderone, S. Giuntini, F. Cantini +2 more
2021Chemical Communications13 citations Open access
Semantic Scholar
Enriching the biological space of natural products and charting drug metabolites, through real time biotransformation monitoring: The NMR tube bioreactor.
A. Chatzikonstantinou, M. Chatziathanasiadou, E. Ravera, M. Fragai +5 more
2018Biochimica et Biophysica Acta - General Subjects13 citations
Semantic Scholar
Integration of NMR Spectroscopy in an Analytical Workflow to Evaluate the Effects of Oxidative Stress on Abituzumab: Beyond the Fingerprint of mAbs
L. Cerofolini, E. Ravera, C. Fischer, Andrea Trovato +5 more
2023Analytical Chemistry12 citations Open access
Semantic Scholar
HuR modulation counteracts lipopolysaccharide response in murine macrophages
I. Bonomo, Giulia Assoni, V. La Pietra, G. Canarutto +15 more
2023bioRxiv12 citations Open access
Semantic Scholar
NMR Study of the Secondary Structure and Biopharmaceutical Formulation of an Active Branched Antimicrobial Peptide
F. Castiglia, Fabrizia Zevolini, Giulia Riolo, J. Brunetti +9 more
2019Molecules12 citations Open access
Semantic Scholar
Biomolecular NMR at 1.2 GHz
L. Banci, Letizia Barbieri, V. Calderone, F. Cantini +14 more
201912 citations
Semantic Scholar
Epitope Mapping and Binding Assessment by Solid-State NMR Provide a Way for the Development of Biologics under the Quality by Design Paradigm
Domenico Rizzo, L. Cerofolini, S. Giuntini, L. Iozzino +7 more
2022Journal of the American Chemical Society11 citations Open access
Semantic Scholar
Expanding the Functions of KHSRP Protein: Insights into DNA G‐Quadruplex Binding
Pasquale Russomanno, P. Zizza, L. Cerofolini, Federica D'Aria +6 more
2025Advancement of science9 citations Open access
Semantic Scholar
Sodium hyaluronate-g-2-((N-(6-aminohexyl)-4-methoxyphenyl)sulfonamido)-N-hydroxyacetamide with enhanced affinity towards MMP12 catalytic domain to be used as visco-supplement with increased degradation resistance.
Gemma Leone, S. Pepi, M. Consumi, S. Lamponi +6 more
2021Carbohydrate Polymers9 citations Open access
Semantic Scholar
Molecular recognition of sialoglycans by streptococcal Siglec-like adhesins: toward the shape of specific inhibitors
Cristina Di Carluccio, R. Forgione, A. Bosso, S. Yokoyama +8 more
2021RSC Chemical Biology9 citations Open access
Semantic Scholar
Metal centers in biomolecular solid-state NMR.
José Malanho Silva, L. Cerofolini, S. Giuntini, V. Calderone +6 more
2019Journal of Structural Biology9 citations Open access
Semantic Scholar
Exploration of zinc-binding groups for the design of inhibitors for the oxytocinase subfamily of M1 aminopeptidases.
Sofia Tsoukalidou, M. Kakou, Ioannis Mavridis, Despoina Koumantou +5 more
2019Bioorganic & Medicinal Chemistry9 citations Open access
Semantic Scholar
Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies
N. Altincekic, Nathalie Jores, F. Löhr, C. Richter +28 more
2024ACS Chemical Biology8 citations Open access
Semantic Scholar
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design
Greta Donati, Vincenzo Maria D'amore, Pasquale Russomanno, L. Cerofolini +13 more
2023Computational and Structural Biotechnology Journal8 citations Open access
Semantic Scholar
Automated Determination of Nuclear Magnetic Resonance Chemical Shift Perturbations in Ligand Screening Experiments: The PICASSO Web Server
V. Laveglia, A. Giachetti, L. Cerofolini, K. Haubrich +3 more
2021Journal of Chemical Information and Modeling8 citations Open access
Semantic Scholar
Not only manganese, but fruit component effects dictate the efficiency of fruit juice as an oral magnetic resonance imaging contrast agent
Giulia Licciardi, Domenico Rizzo, E. Ravera, M. Fragai +2 more
2021NMR in Biomedicine8 citations Open access
Semantic Scholar
Evaluation of the Higher Order Structure of Biotherapeutics Embedded in Hydrogels for Bioprinting and Drug Release
Domenico Rizzo, L. Cerofolini, Anna Pérez-Ràfols, S. Giuntini +4 more
2021Analytical Chemistry8 citations Open access
Semantic Scholar
Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity.
Eirinaios I Vrettos, Ibai E. Valverde, Alba Mascarin, P. Pallier +21 more
2020Chemistry8 citations Open access
Semantic Scholar
Engineering l-asparaginase for spontaneous formation of calcium phosphate bioinspired microreactors.
A. Louka, Irina Matlahov, S. Giuntini, L. Cerofolini +8 more
2018Physical Chemistry, Chemical Physics - PCCP8 citations Open access
Semantic Scholar
Insights into Siglec‐7 Binding to Gangliosides: NMR Protein Assignment and the Impact of Ligand Flexibility
Cristina Di Carluccio, Luis Padilla-Cortés, Marta Tiemblo-Martín, Giulia Roxana Gheorghita +12 more
2025Advancement of science7 citations Open access
Semantic Scholar
Large Protein Assemblies for High-Relaxivity Contrast Agents: The Case of Gadolinium-Labeled Asparaginase
Giulia Licciardi, Domenico Rizzo, Maria Salobehaj, L. Massai +5 more
2022Bioconjugate chemistry7 citations Open access
Semantic Scholar

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