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A. Gillis · SciRah

Researcher profile · Semantic Scholar

A. Gillis

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A. Gillis — researcher profile on SciRah

h-index: 39
Works: 104
Citations: 6,387

Most-cited papers

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.
P. Voorhoeve, C. Sage, M. Schrier, A. Gillis +12 more
2006Cell1,293 citations Open access
Semantic Scholar
POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors.
L. Looijenga, H. Stoop, H. D. de Leeuw, C. A. de Gouveia Brazao +13 more
2003Cancer Research664 citations
Semantic Scholar
High‐throughput microRNAome analysis in human germ cell tumours
A. Gillis, H. Stoop, R. Hersmus, J. Oosterhuis +9 more
2007Journal of Pathology231 citations
Semantic Scholar
Critical Function of AP-2gamma/TCFAP2C in Mouse Embryonic Germ Cell Maintenance1
S. Weber, Dawid Eckert, D. Nettersheim, A. Gillis +7 more
2010Biology of Reproduction201 citations Open access
Semantic Scholar
Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ-cell tumors.
L. Looijenga, H. D. de Leeuw, Monique van Oorschot, R. V. van Gurp +13 more
2003Cancer Research178 citations
Semantic Scholar
Microsatellite instability, mismatch repair deficiency, and BRAF mutation in treatment-resistant germ cell tumors.
F. Honecker, H. Wermann, F. Mayer, A. Gillis +9 more
2009Journal of Clinical Oncology175 citations Open access
Semantic Scholar
Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults.
A. McIntyre, B. Summersgill, B. Grygalewicz, A. Gillis +10 more
2005Cancer Research168 citations
Semantic Scholar
Expression profile of genes from 12p in testicular germ cell tumors of adolescents and adults associated with i(12p) and amplification at 12p11.2–p12.1
Sandrine Rodriguez, O. Jafer, H. Goker, B. Summersgill +10 more
2003Oncogene164 citations Open access
Semantic Scholar
Targeted serum miRNA (TSmiR) test for diagnosis and follow‐up of (testicular) germ cell cancer patients: A proof of principle
A. Gillis, M. Rijlaarsdam, Ronak Eini, L. Dorssers +10 more
2013Molecular Oncology153 citations Open access
Semantic Scholar
Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis.
A. Gillis, Hans A. Stoop, K. Biermann, R. V. van Gurp +6 more
2011International Journal of Andrology149 citations Open access
Semantic Scholar
Role of gain of 12p in germ cell tumour development
L. Looijenga, G. Zafarana, B. Grygalewicz, B. Summersgill +11 more
2003Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS)147 citations
Semantic Scholar
A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ-cell tumours
M. Murray, E. Bell, K. Raby, M. Rijlaarsdam +6 more
2015British Journal of Cancer136 citations Open access
Semantic Scholar
A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.
P. Voorhoeve, C. Sage, M. Schrier, A. Gillis +12 more
2007Advances in Experimental Medicine and Biology135 citations Open access
Semantic Scholar
Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution
A. Ewing, Anthony M. Gacita, L. Wood, F. Ma +17 more
2015Genome Research126 citations Open access
Semantic Scholar
Expression of BLIMP1/PRMT5 and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumors
Dawid Eckert, K. Biermann, D. Nettersheim, A. Gillis +5 more
2008BMC Developmental Biology123 citations Open access
Semantic Scholar
Human Germ Cell Tumors are Developmental Cancers: Impact of Epigenetics on Pathobiology and Clinic
J. Lobo, A. Gillis, C. Jerónimo, R. Henrique +1 more
2019International Journal of Molecular Sciences122 citations Open access
Semantic Scholar
Endogenous Nodal signaling regulates germ cell potency during mammalian testis development
Cassy M. Spiller, C. Feng, A. Jackson, A. Gillis +4 more
2012Development113 citations
Semantic Scholar
Microsatellite instability of germ cell tumors is associated with resistance to systemic treatment.
F. Mayer, A. Gillis, W. Dinjens, J. Oosterhuis +2 more
2002Cancer Research111 citations
Semantic Scholar
X inactivation in human testicular tumors. XIST expression and androgen receptor methylation status.
L. Looijenga, A. Gillis, R. V. van Gurp, A. Verkerk +1 more
1997American Journal of Pathology103 citations
Semantic Scholar
Identification and Validation Model for Informative Liquid Biopsy-Based microRNA Biomarkers: Insights from Germ Cell Tumor In Vitro, In Vivo and Patient-Derived Data
J. Lobo, A. Gillis, A. van den Berg, L. Dorssers +10 more
2019Cells96 citations Open access
Semantic Scholar
Dissecting the molecular pathways of (testicular) germ cell tumour pathogenesis; from initiation to treatment-resistance.
L. Looijenga, A. Gillis, H. Stoop, K. Biermann +1 more
2011International Journal of Andrology78 citations
Semantic Scholar
12p-Amplicon structure analysis in testicular germ cell tumors of adolescents and adults by array CGH
G. Zafarana, B. Grygalewicz, A. Gillis, L. Vissers +9 more
2003Oncogene78 citations
Semantic Scholar
Unique expression patterns of H19 in human testicular cancers of different etiology
A. Verkerk, I. Ariel, Marjolein C. Dekker, T. Schneider +6 more
1997Oncogene71 citations Open access
Semantic Scholar
Aberrant platelet-derived growth factor alpha-receptor transcript as a diagnostic marker for early human germ cell tumors of the adult testis.
S. Mosselman, L. Looijenga, A. Gillis, M. V. van Rooijen +3 more
1996Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell Tumors
M. Rijlaarsdam, D. Tax, A. Gillis, L. Dorssers +3 more
2015PLoS ONE69 citations Open access
Semantic Scholar
Utility of Serum miR-371a-3p in Predicting Relapse on Surveillance in Patients with Clinical Stage I Testicular Germ Cell Cancer.
J. Lobo, R. Leão, A. Gillis, A. van den Berg +12 more
2020European Urology Oncology67 citations
Semantic Scholar
Malignant testicular germ cell tumors in postpubertal individuals with androgen insensitivity: prevalence, pathology and relevance of single nucleotide polymorphism-based susceptibility profiling
M. Cools, K. Wolffenbuttel, R. Hersmus, B. Mendonça +12 more
2017Human Reproduction67 citations Open access
Semantic Scholar
NANOG promoter methylation and expression correlation during normal and malignant human germ cell development
D. Nettersheim, K. Biermann, A. Gillis, K. Steger +2 more
2011Epigenetics66 citations Open access
Semantic Scholar
Coamplification of DAD-R, SOX5, and EKI1 in human testicular seminomas, with specific overexpression of DAD-R, correlates with reduced levels of apoptosis and earlier clinical manifestation.
G. Zafarana, A. Gillis, R. V. van Gurp, P. G. Olsson +5 more
2002Cancer Research66 citations
Semantic Scholar
Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: confirmation of OCT3/4 specificity for germ cell tumours
M. Rijlaarsdam, H. van Herk, A. Gillis, H. Stoop +7 more
2011British Journal of Cancer65 citations Open access
Semantic Scholar
Relevance of microRNAs in normal and malignant development, including human testicular germ cell tumours.
L. Looijenga, A. Gillis, H. Stoop, R. Hersmus +1 more
2007International Journal of Andrology64 citations
Semantic Scholar
Loss of imprinting of IGF2 and not H19 in breast cancer, adjacent normal tissue and derived fibroblast cultures
C. V. van Roozendaal, A. Gillis, J. Klijn, B. van Ooijen +6 more
1998FEBS Letters61 citations
Semantic Scholar
TGF-β1, EGF and FGF4 synergistically induce differentiation of the seminoma cell line TCam-2 into a cell type resembling mixed non-seminoma.
D. Nettersheim, A. Gillis, L. Looijenga, H. Schorle
2011International Journal of Andrology48 citations Open access
Semantic Scholar
Identification of known and novel germ cell cancer‐specific (embryonic) miRs in serum by high‐throughput profiling
M. Rijlaarsdam, T. Agthoven, A. Gillis, S. Patel +3 more
2015Andrology46 citations Open access
Semantic Scholar
Molecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development
L. Dorssers, A. Gillis, H. Stoop, Ronald van Marion +6 more
2018British Journal of Cancer43 citations Open access
Semantic Scholar
Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas
S. Basten, E. Davis, A. Gillis, E. van Rooijen +13 more
2013PLoS Genetics43 citations Open access
Semantic Scholar
Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline
E. Giannoulatou, G. J. Maher, Zhihao Ding, A. Gillis +7 more
2017PLoS ONE41 citations Open access
Semantic Scholar
Defining minimum genomic regions of imbalance involved in testicular germ cell tumors of adolescents and adults through genome wide microarray analysis of cDNA clones
A. McIntyre, B. Summersgill, O. Jafer, Sandrine Rodriguez +8 more
2004Oncogene41 citations
Semantic Scholar
Genomic and expression profiling of human spermatocytic seminomas: pathogenetic implications.
L. Looijenga, H. Stoop, R. Hersmus, A. Gillis +1 more
2007International Journal of Andrology39 citations Open access
Semantic Scholar
The seminoma cell line TCam‐2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression
D. Nettersheim, A. Gillis, K. Biermann, L. Looijenga +1 more
2011Genes, Chromosomes and Cancer36 citations Open access
Semantic Scholar
Differential methylation of the OCT3/4 upstream region in primary human testicular germ cell tumors.
J. de Jong, Sannah Weeda, A. Gillis, J. Oosterhuis +1 more
2007Oncology Report35 citations Open access
Semantic Scholar
Combining Hypermethylated RASSF1A Detection Using ddPCR with miR-371a-3p Testing: An Improved Panel of Liquid Biopsy Biomarkers for Testicular Germ Cell Tumor Patients
J. Lobo, L. V. van Zogchel, Mohammed Nuru, A. Gillis +3 more
2021Cancers34 citations Open access
Semantic Scholar
XIST-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality
J. Lobo, Sandra P. Nunes, A. Gillis, D. Barros-Silva +7 more
2019Cancers31 citations Open access
Semantic Scholar
Cellular origin of microRNA‐371a‐3p in healthy males based on systematic urogenital tract tissue evaluation
W. Boellaard, A. Gillis, G. van Leenders, H. Stoop +5 more
2019Andrology29 citations Open access
Semantic Scholar
The Role of TP53 in Cisplatin Resistance in Mediastinal and Testicular Germ Cell Tumors
Dennis M. Timmerman, T. F. Eleveld, A. Gillis, C. Friedrichs +4 more
2021International Journal of Molecular Sciences28 citations Open access
Semantic Scholar
Role of SOX2 in the Etiology of Embryonal Carcinoma, Based on Analysis of the NCCIT and NT2 Cell Lines
Ronak Eini, H. Stoop, A. Gillis, K. Biermann +2 more
2014PLoS ONE28 citations Open access
Semantic Scholar
JKT-1 is not a human seminoma cell line.
J. de Jong, H. Stoop, A. Gillis, R. V. van Gurp +10 more
2007International Journal of Andrology26 citations Open access
Semantic Scholar
Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence
Lin Xu, Joshua L. Pierce, A. Sanchez, Kenneth S. Chen +22 more
2023Nature Communications25 citations Open access
Semantic Scholar
Chromosome 3p25.3 Gain Is Associated With Cisplatin Resistance and Is an Independent Predictor of Poor Outcome in Male Malignant Germ Cell Tumors
Dennis M. Timmerman, T. F. Eleveld, S. Sriram, L. Dorssers +8 more
2022Journal of Clinical Oncology25 citations Open access
Semantic Scholar
Napabucasin overcomes cisplatin resistance in ovarian germ cell tumor-derived cell line by inhibiting cancer stemness
S. Schmidtova, L. Dorssers, K. Kalavska, A. Gillis +11 more
2020Cancer Cell International25 citations Open access
Semantic Scholar

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L. Looijenga — researcher profile on SciRah
H. Stoop×19
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L. Dorssers — researcher profile on SciRah

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M. Rijlaarsdam — researcher profile on SciRah