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M. Caparon · SciRah

Researcher profile · Semantic Scholar

M. Caparon

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M. Caparon — researcher profile on SciRah

h-index: 66
Works: 167
Citations: 16K

Most-cited papers

Urinary tract infections: epidemiology, mechanisms of infection and treatment options
A. L. Flores-Mireles, Jennifer N. Walker, M. Caparon, S. Hultgren
2015Nature Reviews Microbiology3,834 citations Open access
Semantic Scholar
Lactobacillus reuteri induces gut intraepithelial CD4+CD8αα+ T cells
L. Cervantes-Barragan, Jiani N. Chai, M. Tianero, B. Di Luccia +10 more
2017Science790 citations Open access
Semantic Scholar
A tale of two pili: assembly and function of pili in bacteria
K. Kline, K. Dodson, M. Caparon, S. Hultgren
2010Trends in Microbiology206 citations Open access
Semantic Scholar
EbpA vaccine antibodies block binding of Enterococcus faecalis to fibrinogen to prevent catheter-associated bladder infection in mice
A. L. Flores-Mireles, J. Pinkner, M. Caparon, S. Hultgren
2014Science Translational Medicine192 citations Open access
Semantic Scholar
Enterococcal Biofilm Formation and Virulence in an Optimized Murine Model of Foreign Body-Associated Urinary Tract Infections
P. Guiton, Chia S. Hung, Lynn E. Hancock, M. Caparon +1 more
2010Infection and Immunity178 citations Open access
Semantic Scholar
Patterns of virulence gene expression differ between biofilm and tissue communities of Streptococcus pyogenes
K. Cho, M. Caparon
2005Molecular Microbiology166 citations Open access
Semantic Scholar
Contribution of Autolysin and Sortase A during Enterococcus faecalis DNA-Dependent Biofilm Development
P. Guiton, Chia S. Hung, K. Kline, Robyn Roth +6 more
2009Infection and Immunity154 citations Open access
Semantic Scholar
Catheterization alters bladder ecology to potentiate Staphylococcus aureus infection of the urinary tract
Jennifer N. Walker, A. L. Flores-Mireles, Chloe L. Pinkner, Henry L. Schreiber +9 more
2017Proceedings of the National Academy of Sciences of the United States of America129 citations Open access
Semantic Scholar
The Metal Ion-Dependent Adhesion Site Motif of the Enterococcus faecalis EbpA Pilin Mediates Pilus Function in Catheter-Associated Urinary Tract Infection
H. Nielsen, P. Guiton, K. Kline, Gary C. Port +6 more
2012mBio117 citations Open access
Semantic Scholar
Combinatorial Small-Molecule Therapy Prevents Uropathogenic Escherichia coli Catheter-Associated Urinary Tract Infections in Mice
P. Guiton, Corinne K. Cusumano, K. Kline, K. Dodson +5 more
2012Antimicrobial Agents and Chemotherapy110 citations Open access
Semantic Scholar
Fibrinogen release and deposition on urinary catheters placed during urologic procedures
A. L. Flores-Mireles, Jennifer N. Walker, Tyler M. Bauman, A. Potretzke +6 more
2015Journal of Urology104 citations Open access
Semantic Scholar
Enterococcus faecalis Overcomes Foreign Body-Mediated Inflammation To Establish Urinary Tract Infections
P. Guiton, T. Hannan, B. Ford, M. Caparon +1 more
2012Infection and Immunity103 citations Open access
Semantic Scholar
Mechanism for Sortase Localization and the Role of Sortase Localization in Efficient Pilus Assembly in Enterococcus faecalis
K. Kline, A. Kau, S. Chen, Adeline Lim +8 more
2009Journal of Bacteriology101 citations Open access
Semantic Scholar
Regulation of SpeB in Streptococcus pyogenes by pH and NaCl: a Model for In Vivo Gene Expression
Jennifer A. Loughman, M. Caparon
2006Journal of Bacteriology101 citations Open access
Semantic Scholar
A PerR‐regulated metal transporter (PmtA) is an interface between oxidative stress and metal homeostasis in Streptococcus pyogenes
A. Brenot, B. F. Weston, M. Caparon
2007Molecular Microbiology98 citations
Semantic Scholar
A novel adaptation of aldolase regulates virulence in Streptococcus pyogenes
Jennifer A. Loughman, M. Caparon
2006EMBO Journal98 citations Open access
Semantic Scholar
Streptolysin S Inhibits Neutrophil Recruitment during the Early Stages of Streptococcus pyogenes Infection
Ada Lin, Jennifer A. Loughman, Bernd H. Zinselmeyer, Mark J. Miller +1 more
2009Infection and Immunity85 citations Open access
Semantic Scholar
CcpA and LacD.1 Affect Temporal Regulation of Streptococcus pyogenes Virulence Genes
Colin C. Kietzman, M. Caparon
2009Infection and Immunity83 citations Open access
Semantic Scholar
Focal targeting by human β-defensin 2 disrupts localized virulence factor assembly sites in Enterococcus faecalis
K. Kandaswamy, Tze Horng Liew, Charles Y. Wang, E. Huston-Warren +8 more
2013Proceedings of the National Academy of Sciences of the United States of America79 citations Open access
Semantic Scholar
Virulence Gene Regulation by CvfA, a Putative RNase: the CvfA-Enolase Complex in Streptococcus pyogenes Links Nutritional Stress, Growth-Phase Control, and Virulence Gene Expression
Song O. Kang, M. Caparon, K. Cho
2010Infection and Immunity78 citations Open access
Semantic Scholar
Microbial co-occurrences on catheters from long-term catheterized patients
Taylor M. Nye, Zongsen Zou, Chloe L. P. Obernuefemann, J. Pinkner +11 more
2024Nature Communications73 citations Open access
Semantic Scholar
Antibody-Based Therapy for Enterococcal Catheter-Associated Urinary Tract Infections
A. L. Flores-Mireles, Jennifer N. Walker, A. Potretzke, Henry L. Schreiber +6 more
2016mBio68 citations Open access
Semantic Scholar
tRNA Modification by GidA/MnmE Is Necessary for Streptococcus pyogenes Virulence: a New Strategy To Make Live Attenuated Strains
K. Cho, M. Caparon
2008Infection and Immunity68 citations Open access
Semantic Scholar
Pilin and Sortase Residues Critical for Endocarditis- and Biofilm-Associated Pilus Biogenesis in Enterococcus faecalis
H. Nielsen, A. L. Flores-Mireles, A. Kau, K. Kline +6 more
2013Journal of Bacteriology67 citations Open access
Semantic Scholar
Anionic Lipids Enriched at the ExPortal of Streptococcus pyogenes
J. Rosch, Fong-Fu Hsu, M. Caparon
2006Journal of Bacteriology67 citations Open access
Semantic Scholar
Streptococcus pyogenes cytolysin‐mediated translocation does not require pore formation by streptolysin O
N. Magassa, Sukantha Chandrasekaran, M. Caparon
2010EMBO Reports66 citations Open access
Semantic Scholar
The Metal Homeostasis Protein, Lsp, of Streptococcus pyogenes Is Necessary for Acquisition of Zinc and Virulence
B. F. Weston, A. Brenot, M. Caparon
2009Infection and Immunity65 citations Open access
Semantic Scholar
Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection
Wei Xu, A. L. Flores-Mireles, Zachary T. Cusumano, E. Takagi +2 more
2017npj Biofilms and Microbiomes63 citations Open access
Semantic Scholar
Characterization of a Novel Murine Model of Staphylococcus saprophyticus Urinary Tract Infection Reveals Roles for Ssp and SdrI in Virulence
K. Kline, M. Ingersoll, H. Nielsen, T. Sakinc +4 more
2010Infection and Immunity60 citations Open access
Semantic Scholar
Comparative functional analysis of the lac operons in Streptococcus pyogenes
Jennifer A. Loughman, M. Caparon
2007Molecular Microbiology60 citations Open access
Semantic Scholar
Streptococcus pyogenes Arginine and Citrulline Catabolism Promotes Infection and Modulates Innate Immunity
Zachary T. Cusumano, Michael E. Watson, M. Caparon
2013Infection and Immunity58 citations Open access
Semantic Scholar
Citrulline Protects Streptococcus pyogenes from Acid Stress Using the Arginine Deiminase Pathway and the F1Fo-ATPase
Zachary T. Cusumano, M. Caparon
2015Journal of Bacteriology54 citations Open access
Semantic Scholar
Role of group A Streptococcus HtrA in the maturation of SpeB protease
J. Cole, J. Aquilina, P. Hains, A. Henningham +7 more
2007Proteomics53 citations
Semantic Scholar
High Resolution Imaging Reveals Microbial Biofilms on Patient Urinary Catheters Despite Antibiotic Administration
Jennifer N. Walker, A. L. Flores-Mireles, Aaron J L Lynch, Chloe L. Pinkner +3 more
2019World journal of urology51 citations Open access
Semantic Scholar
A Novel Endogenous Inhibitor of the Secreted Streptococcal NAD-Glycohydrolase
Michael A. Meehl, J. Pinkner, P. Anderson, S. Hultgren +1 more
2005PLoS Pathogens46 citations Open access
Semantic Scholar
Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence
Lu Yu, V. P. O'Brien, J. Livny, Denise A. Dorsey +6 more
2019eLife45 citations Open access
Semantic Scholar
Cationic Antimicrobial Peptides Disrupt the Streptococcus pyogenes ExPortal
L. Vega, M. Caparon
2012Molecular Microbiology45 citations Open access
Semantic Scholar
Specificity of Streptococcus pyogenes NAD+ glycohydrolase in cytolysin‐mediated translocation
Joydeep Ghosh, M. Caparon
2006Molecular Microbiology44 citations Open access
Semantic Scholar
Animal Models of Streptococcus pyogenes Infection
Michael E. Watson, Melody N. Neely, M. Caparon
201641 citations
Semantic Scholar
Characterization of Streptococcus pyogenes β-NAD+ Glycohydrolase
Joydeep Ghosh, P. Anderson, Sukantha Chandrasekaran, M. Caparon
2009Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Murine Vaginal Colonization Model for Investigating Asymptomatic Mucosal Carriage of Streptococcus pyogenes
Michael E. Watson, H. Nielsen, S. Hultgren, M. Caparon
2013Infection and Immunity37 citations Open access
Semantic Scholar
Complete Genome Sequence of emm Type 14 Streptococcus pyogenes Strain HSC5
Gary C. Port, Elyse Paluscio, M. Caparon
2013Genome Announcements33 citations Open access
Semantic Scholar
Variation in Streptococcus pyogenes NAD+ Glycohydrolase Is Associated with Tissue Tropism
David J. Riddle, D. Bessen, M. Caparon
2010Journal of Bacteriology32 citations Open access
Semantic Scholar
The Signal Recognition Particle Pathway Is Required for Virulence in Streptococcus pyogenes
J. Rosch, L. Vega, J. M. Beyer, Ada Lin +1 more
2008Infection and Immunity31 citations Open access
Semantic Scholar
SpxA1 and SpxA2 Act Coordinately To Fine-Tune Stress Responses and Virulence in Streptococcus pyogenes
Gary C. Port, Zachary T. Cusumano, P. Tumminello, M. Caparon
2017mBio29 citations Open access
Semantic Scholar
The Streptococcus pyogenes NAD+ Glycohydrolase Modulates Epithelial Cell PARylation and HMGB1 Release
Sukantha Chandrasekaran, M. Caparon
2015Cellular Microbiology29 citations Open access
Semantic Scholar
Structural Basis of Streptococcus pyogenes Immunity to its NAD+ Glycohydrolase Toxin
Craig L. Smith, Joydeep Ghosh, J. Elam, J. Pinkner +3 more
2011Structure29 citations Open access
Semantic Scholar
Distinct Time-Resolved Roles for Two Catabolite-Sensing Pathways during Streptococcus pyogenes Infection
Colin C. Kietzman, M. Caparon
2010Infection and Immunity29 citations Open access
Semantic Scholar
CcpA Coordinates Growth/Damage Balance for Streptococcus pyogenes Pathogenesis
Elyse Paluscio, Michael E. Watson, M. Caparon
2018Scientific Reports28 citations Open access
Semantic Scholar
Dual modes of membrane binding direct pore formation by Streptolysin O
Cara C. Mozola, M. Caparon
2015Molecular Microbiology28 citations Open access
Semantic Scholar

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A. L. Flores-Mireles×9
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K. Kline×8
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K. Kline — researcher profile on SciRah

Jennifer N. Walker

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P. Guiton — researcher profile on SciRah

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Alana Desai — researcher profile on SciRah

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Jennifer A. Loughman — researcher profile on SciRah

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Zachary T. Cusumano — researcher profile on SciRah