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K. Strein · SciRah

Researcher profile · Semantic Scholar

K. Strein

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K. Strein — researcher profile on SciRah

h-index: 18
Works: 105
Citations: 1,438

Most-cited papers

Target Expression, Generation, Preclinical Activity, and Pharmacokinetics of the BCMA-T Cell Bispecific Antibody EM801 for Multiple Myeloma Treatment.
A. Seckinger, J. A. Delgado, S. Moser, Laura Moreno +27 more
2017Cancer Cell298 citations Open access
Semantic Scholar
BM 21.0955, a potent new bisphosphonate to inhibit bone resorption
R. Mühlbauer, F. Bauss, R. Schenk, M. Janner +3 more
1991Journal of Bone and Mineral Research248 citations
Semantic Scholar
Pharmacological Profile of Carvedilol as a β-Blocking Agent with Vasodilating and Hypotensive Properties
G. Sponer, W. Bartsch, K. Strein, B. Müller-Beckmann +1 more
1987Journal of Cardiovascular Pharmacology105 citations Open access
Semantic Scholar
Pharmacological characteristics of the stereoisomers of carvedilol
W. Bartsch, G. Sponer, K. Strein, B. Müller-Beckmann +4 more
2005European Journal of Clinical Pharmacology64 citations
Semantic Scholar
Evaluation of thrombolytic and systemic effects of the novel recombinant plasminogen activator BM 06.022 compared with alteplase, anistreplase, streptokinase and urokinase in a canine model of coronary artery thrombosis.
Ulrich Martin, G. Sponer, K. Strein
1992Journal of the American College of Cardiology61 citations Open access
Semantic Scholar
Pharmacological Profile of Carvedilol, a Compound with &bgr;‐Blocking and Vasodilating Properties*
K. Strein, G. Sponer, B. Müller-Beckmann, W. Bartsch
1987Journal of Cardiovascular Pharmacology50 citations Open access
Semantic Scholar
Pharmacokinetics of the Novel Recombinant Plasminogen Activator BM 06.022 in Rats, Dogs, and Non-human Primates
U. Martin, J. Köhler, G. Sponer, K. Strein
199244 citations
Semantic Scholar
Studies on the Mode of Vasodilating Action of Carvedilol*
G. Sponer, K. Strein, Bernd Muller-Beckmann, W. Bartsch
1987Journal of Cardiovascular Pharmacology44 citations Open access
Semantic Scholar
Aminoguanidine inhibits albuminuria, but not the formation of advanced glycation end-products in skin collagen of diabetic rats.
T. Degenhardt, M. Fu, E. Voss, Klaus Reiff +5 more
1999Diabetes Research and Clinical Practice40 citations
Semantic Scholar
Thrombolysis with an Escherichia coli-Produced Recombinant Plasminogen Activator (BM 06.022) in the Rabbit Model of Jugular Vein Thrombosis
U. Martin, S. Fischer, U. Kohnert, U. Opitz +4 more
1991Thrombosis and Haemostasis34 citations
Semantic Scholar
Coronary Thrombolytic Properties of a Novel Recombinant Plasminogen Activator (BM 06.022) in a Canine Model
U. Martin, S. Fischer, U. Kohnert, Rainer Rudolph +3 more
1991Journal of Cardiovascular Pharmacology30 citations Open access
Semantic Scholar
Differential fibrinolytic properties of the recombinant plasminogen activator BM 06.022 in human plasma and blood clot systems in vitro
U. Martin, G. Sponer, K. Strein
1993Blood Coagulation and Fibrinolysis28 citations
Semantic Scholar
Influence of hepatic and renal failure on pharmacokinetic properties of the novel recombinant plasminogen activator BM 06.022 in rats.
Ulrich Martin, G. Sponer, K. Strein
1993Drug Metabolism And Disposition21 citations
Semantic Scholar
Double bolus administration of the novel recombinant plasminogen activator BM 06.022 improves coronary blood flow after reperfusion in a canine model of coronary thrombosis
Ulrich Martin, G. Sponer, R. König, A. Smolarz +2 more
1992Blood Coagulation and Fibrinolysis21 citations
Semantic Scholar
Vasodilatory action of carvedilol.
G. Sponer, K. Strein, W. Bartsch, B. Müller-Beckmann
1992Journal of Cardiovascular Pharmacology20 citations Open access
Semantic Scholar
Pharmacokinetic properties of an Escherichia-coli-produced recombinant plasminogen activator (BM 06.022) in rabbits.
U. Martin, S. Fischer, U. Kohnert, Rainer Rudolph +3 more
1991Thrombosis Research20 citations
Semantic Scholar
The pharmacokinetic and pharmacodynamic profiles of the thromboxane A‐2 receptor blocker BM 13.177
H. Patscheke, C. Staiger, G. Neugebauer, B. Kaufmann +3 more
1986Clinical pharmacology and therapy20 citations
Semantic Scholar
Development and characterization of NILK-2301, a novel CEACAM5xCD3 κλ bispecific antibody for immunotherapy of CEACAM5-expressing cancers
A. Seckinger, Sara Majocchi, V. Moine, L. Nouveau +22 more
2023Journal of Hematology & Oncology18 citations Open access
Semantic Scholar
Properties of a novel plasminogen activator (BM 06.022) produced in Escherichia coli.
Ulrich Martin, S. Fischer, Ulrich Kohnert, H. Lill +4 more
1990Zeitschrift für Kardiologie17 citations
Semantic Scholar
Hirudin and sulotroban improve coronary blood flow after reperfusion induced by the novel recombinant plasminogen activator BM 06.022 in a canine model of coronary artery thrombosis.
Ulrich Martin, G. Sponer, K. Strein
1992International journal of hematology15 citations
Semantic Scholar
Ca2+-sensitizing effect of BM 14.478 on skinned cardiac muscle fibres of guinea-pig papillary muscle.
P. Freund, B. Müller-Beckmann, K. Strein, L. Kling +1 more
1987European Journal of Pharmacology15 citations
Semantic Scholar
Pharmacokinetic aspects of isosorbide-5-mononitrate in dogs.
G. Sponer, H. Kuhnle, K. Strein, W. Bartsch +2 more
1984Journal of Pharmacology and Experimental Therapeutics15 citations
Semantic Scholar
Diarylsulfonamides as selective, non-peptidic thrombin inhibitors.
Ingo R. Weber, Richard Neidlein, W. von der Saal, Frank Grams +4 more
1998Bioorganic & Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Rapid Reversal of Canine Thromboembolic Pulmonary Hypertension by Bolus Injection of the Novel Recombinant Plasminogen Activator BM 06.022
Ulrich Martin, G. Sponer, K. Strein
1993Journal of Cardiovascular Pharmacology13 citations Open access
Semantic Scholar
Experimental and clinical pharmacology of carvedilol and other drugs combining vasodilation and beta-adrenoceptor antagonism in a single molecule.
K. Strein, G. Sponer
1990Zeitschrift für Kardiologie13 citations
Semantic Scholar
Evaluation of the Risk for Drug‐Induced Postural Hypotension in an Experimental Model: Investigations with Carvedilol, Prazosin, Labetalol, and Guanethidine*
W. Bartsch, G. Sponer, K. Strein, E. Böhm +1 more
1987Journal of Cardiovascular Pharmacology12 citations Open access
Semantic Scholar
Target Expression, Preclinical Activity and Mechanism of Action of EM801: A Novel First-in-Class Bcma T-Cell Bispecific Antibody for the Treatment of Multiple Myeloma
A. Seckinger, J. A. Delgado, Laura Moreno, Brigitte Neuber +10 more
201511 citations
Semantic Scholar
Dose-dependent effects of isosorbide-5-mononitrate on the venous arterial and coronary arterial system of conscious dogs
E. Bassenge, K. Strein
1986Naunyn-Schmiedeberg's Archives of Pharmacology11 citations
Semantic Scholar
Effects of Isosorbide-5-Mononitrate on Hemodynamic Parameters and on Regional Myocardial Ischemia in Conscious Dogs
K. Strein, Voss Em, G. Sponer, B. Müller-Beckmann +1 more
198511 citations
Semantic Scholar
A Short Synthesis of the Factor-Xa Inhibitor DX-9065a using palladium-catalyzed key steps†‡
C. Kehr, R. Neidlein*, R. Engh, Hans Brandsretter +5 more
199710 citations
Semantic Scholar
Hemodynamic Profile of BM 14.478: A New Positive Inotropic and Vasodilating Agent
B. Müller-Beckmann, G. Sponer, K. Strein, W. Bartsch
1988Journal of Cardiovascular Pharmacology10 citations Open access
Semantic Scholar
Beta-adrenergic receptor mediated release of tissue plasminogen activator in anaesthetized dogs.
A. Probst, Helmut Lill, K. Strein
1988Thrombosis Research10 citations
Semantic Scholar
Electrocardiographic analysis of the effects of isosorbide-5-mononitrate on regional myocardial ischemia in conscious dogs.
K. Strein, G. Sponer, W. Bartsch, Bernd Muller-Beckmann +1 more
1984Journal of Pharmacology and Experimental Therapeutics10 citations
Semantic Scholar
New Insights into the Mechanism of Action (MoA) of First-in-Class IgG-Based Bcma T-Cell Bispecific Antibody (TCB) for the Treatment of Multiple Myeloma (MM)
Laura Moreno, A. Zabaleta, D. Alignani, M. Lasa +10 more
20169 citations
Semantic Scholar
Pharmacokinetic and thrombolytic properties of unglycosylated recombinant tissue-type plasminogen activator (BM 06.021) produced in Escherichia coli
Ulrich Martin, S. Fischer, Ulrich Kohnert, Ulrich Opitz +4 more
1992Naunyn-Schmiedeberg's Archives of Pharmacology8 citations
Semantic Scholar
A New Class of T-Cell Bispecific Antibodies for the Treatment of Multiple Myeloma, Binding to B Cell Maturation Antigen and CD3 and Showing Potent, Specific Antitumor Activity in Myeloma Cells and Long Duration of Action in Cynomolgus Monkeys
M. D. Vu, S. Moser, C. Delon, Melanie Latzko +19 more
20157 citations
Semantic Scholar
LDL-metabolism of the arterial wall--new implications for atherogenesis.
H. A. Dresel, H. Deigner, J. Frübis, K. Strein +1 more
1990Zeitschrift für Kardiologie6 citations
Semantic Scholar
Differences in the nitrite ion formation and the toxicological findings between isosorbide dinitrate and isosorbide-5-mononitrate.
K. Strein, W. Bartsch, G. Sponer, B. Müller-Beckmann +1 more
1984Toxicology and Applied Pharmacology6 citations
Semantic Scholar
Pharmacodynamics of Organic Nitrates - In Vitro and In Vivo Studies
K. Strein, F. Bossert, W. Bartsch, R. Hooper
19874 citations
Semantic Scholar
Production of sequence specific polyclonal antibodies to human parathyroid hormone 1-37 by immunization with multiple antigenic peptides.
M. Magerlein, D. Hock, K. Adermann, R. Neidlein* +2 more
1998Arzneimittel-Forschung3 citations
Semantic Scholar
853 Novel CEAxCD47 (NILK-2401) and CEAxCD3 (NILK-2301) kl bispecific antibodies for multimodal immunotherapy of CEA-expressing solid cancer
A. Seckinger, V. Buatois, V. Moine, L. Nouveau +13 more
2022Regular and Young Investigator Award Abstracts2 citations Open access
Semantic Scholar
752P Novel CEAxCD3 (NILK-2301) and CEAxCD28 (NILK-3301) κλ bispecific antibodies for next generation immunotherapy of CEA-expressing cancer
A. Seckinger, S. Majocchi, V. Moine, L. Nouveau +13 more
2022Annals of Oncology2 citations Open access
Semantic Scholar
Dose proportionality studies of novel thiazolidinedione derivatives as potent antidiabetic agents in mice.
T. Heitzmann, Richard Neidlein, P. Freund, K. Reiff +1 more
1995Arzneimittel-Forschung2 citations
Semantic Scholar
Pharmacokinetics of t-PA produced in E. coli, in conscious dogs
U. Martin, B. Kaufmann, J. Köhler, G. Sponer +1 more
19902 citations
Semantic Scholar
[Nitrate therapy--a causal therapy of the angina pectoris syndrome? New knowledge on the endothelium-derived relaxing factor].
P. Hütter, K. Strein
1988Fortschritte der Medizin2 citations
Semantic Scholar
Activation of Counter-Regulatory Mechanisms on Administration of Equipotent Doses of Different Types of Vasodilators to Conscious Dogs
G. Sponer, E. Mierzwa, K. Strein, B. Müller-Beckmann
19852 citations
Semantic Scholar
Differences in the Metabolism of Isosorbide-5-Mononitrate and Isosorbide Dinitrate and Their Consequences for Toxicologic Findings
K. Strein, G. Sponer, W. Bartsch
19852 citations
Semantic Scholar
Isosorbide-5-Mononitrate Increases Cyclic Guanosine Monophosphate Concentration in Rat Aorta in Vitro and in Vivo
W. Bartsch, K. Strein, E. Böhm, G. Sponer +1 more
19852 citations
Semantic Scholar
Investigations into the development of tolerance to organic nitrates in conscious dogs.
G. Sponer, K. Strein, K. Dietmann, U. Abshagen
1984Arzneimittel-Forschung2 citations
Semantic Scholar
Pharmacological Spectrum of Metipranolol and Experience in Clinical Use
W. Bartsch, G. Sponer, K. Strein
19842 citations
Semantic Scholar

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G. Sponer×30
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B. Müller-Beckmann×10
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U. Martin×6
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D. Hose — researcher profile on SciRah

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S. Fischer — researcher profile on SciRah

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Anne Stern — researcher profile on SciRah

A. Seckinger×4

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M. D. Vu — researcher profile on SciRah

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