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Alexandre Lucas · SciRah

Researcher profile · Semantic Scholar

Alexandre Lucas

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Alexandre Lucas — researcher profile on SciRah

h-index: 14
Works: 28
Citations: 1,197

Most-cited papers

The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes
L. Pereira, M. Métrich, M. Fernández-Velasco, Alexandre Lucas +8 more
2007Journal of Physiology229 citations Open access
Semantic Scholar
Epac Mediates &bgr;-Adrenergic Receptor–Induced Cardiomyocyte Hypertrophy
M. Métrich, Alexandre Lucas, M. Gastineau, J. Samuel +3 more
2008Circulation Research190 citations Open access
Semantic Scholar
Identification of a Tetrahydroquinoline Analog as a Pharmacological Inhibitor of the cAMP-binding Protein Epac*
D. Courilleau, Malik Bisserier, Jean-Christophe Jullian, Alexandre Lucas +4 more
2012Journal of Biological Chemistry103 citations Open access
Semantic Scholar
Multifunctional Mitochondrial Epac1 Controls Myocardial Cell Death
L. Fazal, M. Laudette, Sílvia Paula-Gomes, S. Pons +12 more
2017Circulation Research97 citations Open access
Semantic Scholar
The cAMP binding protein Epac regulates cardiac myofilament function
O. Cazorla, Alexandre Lucas, Florence Poirier, A. Lacampagne +5 more
2009Proceedings of the National Academy of Sciences of the United States of America92 citations Open access
Semantic Scholar
Epac enhances excitation-transcription coupling in cardiac myocytes
L. Pereira, G. Ruiz-Hurtado, E. Morel, Anne-Coline Laurent +8 more
2011Journal of Molecular and Cellular Cardiology79 citations Open access
Semantic Scholar
Exchange protein directly activated by cAMP 1 promotes autophagy during cardiomyocyte hypertrophy.
Anne-Coline Laurent, Malik Bisserier, Alexandre Lucas, F. Tortosa +7 more
2015Cardiovascular Research74 citations
Semantic Scholar
Specific interactions between Epac1, β-arrestin2 and PDE4D5 regulate β-adrenergic receptor subtype differential effects on cardiac hypertrophic signaling.
Magali Berthouze-Duquesnes, Alexandre Lucas, A. Saulière, Yuan-Yan Sin +4 more
2013Cellular Signalling69 citations
Semantic Scholar
Gadd45γ regulates cardiomyocyte death and post-myocardial infarction left ventricular remodelling.
Alexandre Lucas, J. Mialet-Perez, D. Daviaud, A. Parini +2 more
2015Cardiovascular Research55 citations Open access
Semantic Scholar
Two transmembrane Cys residues are involved in 5-HT4 receptor dimerization.
M. Berthouze, L. Rivail, Alexandre Lucas, M. Ayoub +6 more
2007Biochemical and Biophysical Research Communications - BBRC50 citations
Semantic Scholar
Carabin Protects Against Cardiac Hypertrophy by Blocking Calcineurin, Ras, and Ca2+/Calmodulin-Dependent Protein Kinase II Signaling
Malik Bisserier, Magali Berthouze-Duquesnes, Magali Breckler, F. Tortosa +15 more
2014Circulation46 citations
Semantic Scholar
Epac stimulation induces rapid increases in connexin43 phosphorylation and function without preconditioning effect
Nicolas Duquesnes, M. Derangeon, M. Métrich, Alexandre Lucas +5 more
2010Pflügers Archiv: European Journal of Physiology31 citations
Semantic Scholar
Cyclic AMP-binding protein Epac1 acts as a metabolic sensor to promote cardiomyocyte lipotoxicity
M. Laudette, Y. Sainte-Marie, Grégoire Cousin, Dorian Bergonnier +14 more
2021Cell Death and Disease25 citations Open access
Semantic Scholar
Mechanisms of artemether toxicity on single cardiomyocytes and protective effect of nanoencapsulation
Ana Carolina Moreira Souza, A. Grabe-Guimarães, Jader dos Santos Cruz, A. Santos-Miranda +7 more
2020British Journal of Pharmacology20 citations Open access
Semantic Scholar
Epac Mediates -Adrenergic Receptor–Induced Cardiomyocyte Hypertrophy
M. Métrich, Alexandre Lucas, M. Gastineau, J. Samuel +3 more
200813 citations
Semantic Scholar
Monoamine Oxidase Inhibitors Prevent Glucose-Dependent Energy Production, Proliferation and Migration of Bladder Carcinoma Cells
J. Resta, Yohan Santin, M. Roumiguié, Élodie Riant +6 more
2022International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
EPAC1 Pharmacological Inhibition with AM-001 Prevents SARS-CoV-2 and Influenza A Virus Replication in Cells
C. Foret-Lucas, Thomas Figueroa, Alexandre Bertin, P. Bessière +7 more
2023Viruses9 citations Open access
Semantic Scholar
The cAMP binding protein Epac regulates cardiac myofilament function
O. Cazorla, Alexandre Lucas, Florence Poirier, A. Lacampagne +1 more
2009Proceedings of the National Academy of Sciences of the United States of America7 citations Open access
Semantic Scholar
Epac 1 Is Activated by Soluble Adenylyl Cyclase During Hypoxia / Reoxygenation to Transduce Cardiomyocyte Death
L. Fazal, M. Laudette, Sílvia Paula-Gomes, S. Pons +12 more
20170 citations
Semantic Scholar
P142Gadd45 gamma regulates cardiomyocytes death and post-myocardial infarction left ventricular remodeling
Alexandre Lucas, J. Mialet-Perez, A. Parini, M. Marber +1 more
20140 citations Open access
Semantic Scholar
0237: Gadd45 γ promotes cardiac dysfunction by inducing necroptosis pathway in a mouse model of chronic myocardial infarction
Alexandre Lucas, J. Mialet-Perez, L. Lorgis, F. Lezoualc'h +3 more
20140 citations Open access
Semantic Scholar
P86Epac1-induced cardiac hypertrophy triggers autophagy
Malik Bisserier, Anne-Coline Laurent, F. Tortosa, Alexandre Lucas +2 more
20140 citations Open access
Semantic Scholar
Carabin Protects Against Cardiac Hypertrophy by Blocking Calcineurin, Ras and CaMKII Signaling
Malik Bisserier, Magali Berthouze-Duquesnes, Magali Breckler, F. Tortosa +14 more
20140 citations
Semantic Scholar
J028 New insights into the role of Epac in cardiac myocytes signalling and hypertrophy
E. Morel, M. Métrich, Nicolas Duquesnes, Alexandre Lucas +3 more
20090 citations Open access
Semantic Scholar
J006 Beta-adrenergic stimulation activates protein kinase C-epsilon through Epac in cardiomyocytes
Nicolas Duquesnes, M. Métrich, Lin Li, Alexandre Lucas +5 more
20090 citations Open access
Semantic Scholar
Beta-adrenergic Stimulation Activates Protein Kinase C{varepsilon} through Epac in Cardiomyocytes
Nicolas Duquesnes, Lin Li, E. Morel, M. Métrich +5 more
20090 citations
Semantic Scholar
Beta‐adrenergic Stimulation Activates Protein Kinase Cε through Epac in Cardiomyocytes
Nicolas Duquesnes, Lin Li, E. Morel, M. Métrich +5 more
20090 citations
Semantic Scholar
Regulation of cardiomyocyte growth by the cAMP-binding protein Epac
M. Métrich, Alexandre Lucas, M. Gastineau, E. Morel +1 more
20070 citations
Semantic Scholar

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F. Lezoualc'h×18
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F. Lezoualc'h — researcher profile on SciRah
E. Morel×12
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M. Métrich×10
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Malik Bisserier×7
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J. Mialet-Perez×7

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