Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

J. Dubovsky · SciRah

Researcher profile · Semantic Scholar

J. Dubovsky

Share profile

J. Dubovsky — researcher profile on SciRah

h-index: 22
Works: 88
Citations: 3,290

Most-cited papers

Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes.
J. Dubovsky, Kyle A. Beckwith, G. Natarajan, J. Woyach +25 more
2013Blood762 citations Open access
Semantic Scholar
Ibrutinib for chronic graft-versus-host disease after failure of prior therapy.
D. Miklos, C. Cutler, M. Arora, E. Waller +13 more
2017Blood444 citations Open access
Semantic Scholar
Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL).
J. Woyach, Engin Bojnik, A. Ruppert, Matthew R. Stefanovski +15 more
2014Blood232 citations Open access
Semantic Scholar
Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans.
R. Flynn, Jing Du, Rachelle G. Veenstra, D. Reichenbach +19 more
2014Blood205 citations Open access
Semantic Scholar
Myeloid-derived suppressor cells express Bruton’s tyrosine kinase and can be depleted in tumor bearing hosts by ibrutinib treatment
Andrew Stiff, P. Trikha, R. Wesolowski, K. Kendra +20 more
2016Cancer Research176 citations Open access
Semantic Scholar
Hypermorphic mutation of phospholipase C, γ2 acquired in ibrutinib-resistant CLL confers BTK independency upon B-cell receptor activation.
Ta-Ming Liu, J. Woyach, Yiming Zhong, A. Lozanski +14 more
2015Blood174 citations Open access
Semantic Scholar
Ibrutinib treatment ameliorates murine chronic graft-versus-host disease.
J. Dubovsky, R. Flynn, Jing Du, Bonnie K. Harrington +26 more
2014Journal of Clinical Investigation174 citations Open access
Semantic Scholar
Kinetics of chimerism during the early post-transplant period in pediatric patients with malignant and non-malignant hematologic disorders: implications for timely detection of engraftment, graft failure and rejection
J. Dubovsky, H. Daxberger, Gerhard Fritsch, D. Printz +4 more
1999Leukemia146 citations Open access
Semantic Scholar
IPI-145 antagonizes intrinsic and extrinsic survival signals in chronic lymphocytic leukemia cells.
Shuai Dong, Daphne Guinn, J. Dubovsky, Yiming Zhong +5 more
2014Blood102 citations Open access
Semantic Scholar
Proteomic Characterization of Circulating Extracellular Vesicles Identifies Novel Serum Myeloma Associated Markers
S. Harshman, A. Canella, Paul D. Ciarlariello, Kitty Agarwal +14 more
2016Journal of Proteomics86 citations Open access
Semantic Scholar
Analysis of chimerism within specific leukocyte subsets for detection of residual or recurrent leukemia in pediatric patients after allogeneic stem cell transplantation
Thomas Lion, H. Daxberger, J. Dubovsky, P. Filipcik +6 more
2001Leukemia86 citations Open access
Semantic Scholar
Selinexor suppresses Downstream Effectors of B-cell activation, proliferation and migration in chronic lymphocytic leukemia cells
Yiming Zhong, Dalia El-Gamal, J. Dubovsky, Kyle A. Beckwith +14 more
2014Leukemia57 citations Open access
Semantic Scholar
Lymphocyte cytosolic protein 1 is a chronic lymphocytic leukemia membrane-associated antigen critical to niche homing.
J. Dubovsky, D. Chappell, Bonnie K. Harrington, Kitty Agrawal +8 more
2013Blood54 citations Open access
Semantic Scholar
Inducible expression of a prostate cancer‐testis antigen, SSX‐2, following treatment with a DNA methylation inhibitor
J. Dubovsky, D. McNeel
2007The Prostate50 citations
Semantic Scholar
Treatment of Chronic Lymphocytic Leukemia with a Hypomethylating Agent Induces Expression of NXF2, an Immunogenic Cancer Testis Antigen
J. Dubovsky, D. McNeel, John J. Powers, J. Gordon +2 more
2009Clinical Cancer Research48 citations
Semantic Scholar
Targeting Interleukin-2-inducible T-cell Kinase (ITK) and Resting Lymphocyte Kinase (RLK) Using a Novel Covalent Inhibitor PRN694
Yiming Zhong, Shuai Dong, E. Strattan, L. Ren +13 more
2014Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Humoral immune responses to testis antigens in sera from patients with prostate cancer.
Luke H. Hoeppner, J. Dubovsky, E. Dunphy, D. McNeel
2006Cancer Immunity45 citations
Semantic Scholar
Ibrutinib enhances IL-17 response by modulating the function of bone marrow derived dendritic cells
G. Natarajan, César A. Terrazas, S. Oghumu, Sanjay Varikuti +3 more
2016Oncoimmunology43 citations Open access
Semantic Scholar
Panniculitis in Patients Undergoing Treatment With the Bruton Tyrosine Kinase Inhibitor Ibrutinib for Lymphoid Leukemias.
S. Fabbro, Sabrina M. Smith, J. Dubovsky, A. Gru +1 more
2015JAMA Oncology37 citations Open access
Semantic Scholar
A Molecular and Functional Analysis of Large Granular Lymphocyte Expansions in Chronic Myelogenous Leukemia Patients Treated With Tyrosine Kinase Inhibitors
John J. Powers, J. Dubovsky, P. Epling-Burnette, L. Moscinski +4 more
2011Leukemia and Lymphoma37 citations Open access
Semantic Scholar
The B-cell receptor pathway: a critical component of healthy and malignant immune biology.
Yiming Zhong, J. Byrd, J. Dubovsky
2014Seminars in hematology (Print)26 citations
Semantic Scholar
Targeting Interleukin-2-Inducible T-cell Kinase (ITK) in T-Cell Related Diseases
Yiming Zhong, A. Johnson, J. Byrd, J. Dubovsky
2014Postdoc Journal23 citations Open access
Semantic Scholar
Multiplexed Immunofluorescence (IF) Analysis and Gene Expression Profiling of Biopsies from Patients with Relapsed/Refractory (R/R) Diffuse Large B Cell Lymphoma (DLBCL) Treated with Lisocabtagene Maraleucel (liso-cel) in Transcend NHL 001 Reveal Patterns of Immune Infiltration Associated with Durab
David J. Reiss, Trevor Do, David Kuo, Vanessa E. Gray +10 more
2019Blood22 citations Open access
Semantic Scholar
Rapid MRD-Negative Responses in Patients with Relapsed/Refractory CLL Treated with Liso-Cel, a CD19-Directed CAR T-Cell Product: Preliminary Results from Transcend CLL 004, a Phase 1/2 Study Including Patients with High-Risk Disease Previously Treated with Ibrutinib
T. Siddiqi, J. Soumerai, W. Wierda, J. Dubovsky +6 more
2018Blood22 citations Open access
Semantic Scholar
Pilot trial of ibrutinib in patients with relapsed or refractory T-cell lymphoma.
Anita Kumar, Santosha A. Vardhana, A. Moskowitz, P. Porcu +6 more
2018Blood Advances22 citations Open access
Semantic Scholar
Flow cytometric monitoring of hematopoietic reconstitution in myeloablated patients following allogeneic transplantation.
G. Fritsch, V. Witt, J. Dubovsky, S. Matthes +6 more
1999Cytotherapy20 citations
Semantic Scholar
Multicenter Open-Label Phase 2 Study of Ibrutinib in Chronic Graft Versus Host Disease (cGVHD) after Failure of Corticosteroids
D. Miklos, C. Cutler, M. Arora, E. Waller +12 more
201618 citations
Semantic Scholar
TRANSCEND CLL 004: Minimal residual disease (MRD) negative responses after lisocabtagene maraleucel (Liso-Cel; JCAR017), a CD19-directed CAR T cell product, in patients (pts) with relapsed/refractory chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL).
T. Siddiqi, K. Dorritie, J. Soumerai, D. Stephens +6 more
2019Journal of Clinical Oncology15 citations
Semantic Scholar
Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2′-deoxycytidine
J. Dubovsky, John J. Powers, Yang Gao, L. Mariusso +2 more
2011Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis15 citations Open access
Semantic Scholar
Restoring the Functional Immunogenicity of Chronic Lymphocytic Leukemia Using Epigenetic Modifiers
J. Dubovsky, Dan Wang, John J. Powers, Emmanuel Berchmans +4 more
2010Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis15 citations Open access
Semantic Scholar
The biological basis for immunotherapy in patients with chronic myelogenous leukemia.
J. Pinilla-Ibarz, B. Shah, J. Dubovsky
2009Cancer Control: Journal of the Moffitt Cancer Cente14 citations Open access
Semantic Scholar
MAD-CT-2 Identified as a Novel Melanoma Cancer-testis Antigen Using Phage Immunoblot Analysis
J. Dubovsky, M. Albertini, D. McNeel
2007Journal of immunotherapy13 citations
Semantic Scholar
Circumventing immune tolerance through epigenetic modification.
J. Dubovsky, A. Villagra, John J. Powers, Hong-Wei Wang +2 more
2010Current pharmaceutical design12 citations
Semantic Scholar
Phase II Study of Lenalidomide in Combination with Rituximab for Patients with CD5+/CD20+ Hematologic Malignancies Who Relapse or Progress After Rituximab. Interim Analysis.
M. Veliz, R. Santana, J. Lancet, R. Komrokji +7 more
20097 citations Open access
Semantic Scholar
Take (STAT)5: jazzing up T-cell leukemia.
P. Porcu, J. Dubovsky
2014Blood6 citations Open access
Semantic Scholar
Prostate carcinoma in transgenic Lewis rats - a tumor model for evaluation of immunological treatments
Laura E. Johnson, Jordan T. Becker, J. Dubovsky, B. Olson +1 more
2013Chinese Clinical Oncology6 citations
Semantic Scholar
Ibrutinib Inhibits cGVHD Pathogenic Pre-Germinal Center B-Cells and Follicular Helper Cells While Preserving Immune Memory and Th1 T-Cells
B. Sahaf, Dmitry Tebaykin, M. Hopper, P. Cheung +18 more
20175 citations
Semantic Scholar
Hypermorphic mutation of phospholipase C, gamma 2 acquired in ibrutinib resistant CLL confers BTK independency upon BCR activation
Ta-Ming Liu, J. Woyach, Yiming Zhong, A. Lozanski +16 more
20154 citations
Semantic Scholar
Second generation CD2-targeting LFA-3 fusion protein SBT115301 to restore immune homeostasis in autoimmune disease
Herve Lebrec, J. Bui, J. Clingan, Jason Do +10 more
2025iScience3 citations Open access
Semantic Scholar
Ibrutinib for Chronic Graft-Versus-Host Disease: A Safety and Pharmacokinetic Analysis in Patients Treated with Concomitant Antifungal CYP3A Inhibitors or Immunosuppressants
C. Cutler, S. Jaglowski, M. Arora, E. Waller +12 more
20183 citations Open access
Semantic Scholar
A randomized, double-blind phase III study of ibrutinib versus placebo in combination with corticosteroids in patients with new onset chronic graft versus host disease.
D. Miklos, M. Jagasia, H. Greinix, B. Ko +7 more
20173 citations
Semantic Scholar
Global Inhibition of Bruton's Tyrosine Kinase (BTK) Delays the Development and Expansion of Chronic Lymphocytic Leukemia (CLL) in the TCL1 Mouse Model of Disease
J. Woyach, Matthew R. Stefanovski, V. Goettl, A. Ruppert +11 more
20123 citations
Semantic Scholar
Ibrutinib Is an Irreversible Molecular Inhibitor of Interleukin-2 Inducible Kinase: Expanding Therapeutic Potential and Modulating a Th1 Selective Pressure in CD4 T-Cells
J. Dubovsky, Kyle A. Beckwith, J. Woyach, S. Jaglowski +20 more
20123 citations
Semantic Scholar
Pharmacologic Inhibition with Duvelisib (IPI-145) and Genetic Inhibition of PI3K p110δ Antagonizes Intrinsic and Extrinsic Survival Signals in Chronic Lymphocytic Leukemia (CLL)
Shuai Dong, Daphne Guinn, J. Dubovsky, Yiming Zhong +5 more
20142 citations
Semantic Scholar
Enhanced Immunological Responses Following K562/GM-CSF/CD40L Vaccine Plus Lenalidomide in High-Risk Myelodysplastic Syndrome
J. Powers, E. Padron, J. Dubovsky, Emmanuel Berchmans +13 more
20112 citations
Semantic Scholar
A Comprehensive Lymphocyte Analysis of Dasatinib Treated Chronic Myelogenous Leukemia Patients Reveals T-Cell Oligoclonality.
John J. Powers, J. Painter, J. Dubovsky, P. Epling-Burnette +1 more
20082 citations
Semantic Scholar
TRANSCEND CLL 004: MINIMAL RESIDUAL DISEASE AFTER LISOCABTAGENE MARALEUCEL IN PATIENTS WITH RELAPSED/REFRACTORY CHRONIC LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LYMPHOMA
T. Siddiqi, K. Dorritie, J. Soumerai, D. Stephens +6 more
2019Hematological Oncology1 citations Open access
Semantic Scholar
Ibrutinib-Mediated Inhibition of cGVHD Pathogenic Pre-Germinal Center B-Cells and Follicular Helper Cells While Preserving Immune Memory and Th1 T-Cells
B. Sahaf, Dmitry Tebaykin, M. Hopper, P. Cheung +18 more
20181 citations Open access
Semantic Scholar
Abstract 2591: Ibrutinib can reverse established chronic graft-versus-host disease, which is dependent upon IL-2 inducible T-cell kinase (ITK) and Bruton's tyrosine kinase (BTK)-driven lymphocyte activation
J. Dubovsky, R. Flynn, Jing Du, Bonnie K. Harrington +22 more
20141 citations
Semantic Scholar
Germinal Center Generation and Maintenance By T Follicular Helper Cells Is Required For The Development Of Chronic Gvhd Associated Bronchiolitis Obliterans In a Preclinical Model
R. Flynn, Jing Du, Rachelle G. Veenstra, A. Panoskaltsis-Mortari +20 more
20131 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

J. Byrd×18
Invite
J. Byrd — researcher profile on SciRah
A. Johnson×13
Invite
A. Johnson — researcher profile on SciRah
S. Jaglowski×11
Invite
S. Jaglowski — researcher profile on SciRah
Yiming Zhong×11
Invite
Yiming Zhong — researcher profile on SciRah

×9

Invite

C. Cutler — researcher profile on SciRah

Invite

J. Woyach — researcher profile on SciRah

Invite

A. Lehman — researcher profile on SciRah

J. Pinilla-Ibarz×8

Invite

J. Pinilla-Ibarz — researcher profile on SciRah

Jeffrey A. Jones×7

Invite

Jeffrey A. Jones — researcher profile on SciRah

E. Sotomayor×7

Invite

E. Sotomayor — researcher profile on SciRah

Invite

J. Flynn — researcher profile on SciRah

L. Andritsos×6

Invite

L. Andritsos — researcher profile on SciRah