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C. Lepage · SciRah

Researcher profile · Semantic Scholar

C. Lepage

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C. Lepage — researcher profile on SciRah

h-index: 48
Works: 265
Citations: 8,330

Most-cited papers

Digestive Neuroendocrine Neoplasms (NEN): French Intergroup clinical practice guidelines for diagnosis, treatment and follow-up (SNFGE, GTE, RENATEN, TENPATH, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, SFR).
L. de Mestier, C. Lepage, E. Baudin, R. Coriat +15 more
2020Digestive and Liver Disease127 citations
Semantic Scholar
Intratumor CMS Heterogeneity Impacts Patient Prognosis in Localized Colon Cancer
L. Marisa, Y. Blum, J. Taieb, M. Ayadi +16 more
2021Clinical Cancer Research57 citations Open access
Semantic Scholar
Randomized Phase II Trial Evaluating Two Sequential Treatments in First Line of Metastatic Pancreatic Cancer: Results of the PANOPTIMOX-PRODIGE 35 Trial
L. Dahan, N. Williet, K. Le Malicot, J. Phelip +14 more
2021Journal of Clinical Oncology55 citations
Semantic Scholar
Phase 2 trial comparing sorafenib, pravastatin, their combination or supportive care in HCC with Child–Pugh B cirrhosis
J. Blanc, F. Khemissa, J. Bronowicki, C. Montérymard +60 more
2021Hepatology International48 citations Open access
Semantic Scholar
COVID-19 epidemic: Proposed alternatives in the management of digestive cancers: A French intergroup clinical point of view (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, SFR)
F. Di Fiore, O. Bouché, C. Lepage, D. Sefrioui +10 more
2020Digestive and Liver Disease42 citations Open access
Semantic Scholar
Bevacizumab plus FOLFIRI after failure of platinum-etoposide first-line chemotherapy in patients with advanced neuroendocrine carcinoma (PRODIGE 41-BEVANEC): a randomised, multicentre, non-comparative, open-label, phase 2 trial.
T. Walter, A. Lièvre, R. Coriat, D. Malka +17 more
2023The Lancet Oncology41 citations Open access
Semantic Scholar
Avelumab vs Standard Second-Line Chemotherapy in Patients With Metastatic Colorectal Cancer and Microsatellite Instability
Julien Taïeb, O. Bouché, T. André, K. Le Malicot +15 more
2023JAMA Oncology41 citations Open access
Semantic Scholar
Implementation and use of whole exome sequencing for metastatic solid cancer
M. Réda, C. Richard, A. Bertaut, J. Niogret +21 more
2020EBioMedicine39 citations Open access
Semantic Scholar
"Decision for adjuvant treatment in stage II colon cancer based on circulating tumor DNA:The CIRCULATE-PRODIGE 70 trial".
Julien Taïeb, L. Benhaim, P. Laurent-Puig, K. Le Malicot +8 more
2020Digestive and Liver Disease36 citations Open access
Semantic Scholar
LBA41 Nivolumab (nivo) ± ipilimumab (ipi) in pre-treated patients with advanced, refractory pulmonary or gastroenteropancreatic poorly differentiated neuroendocrine tumors (NECs) (GCO-001 NIPINEC)
N. Girard, J. Mazières, J. Otto, H. Léna +16 more
2021Annals of Oncology33 citations Open access
Semantic Scholar
Study of Small Intestinal Bacterial Overgrowth in a Cohort of Patients with Abdominal Symptoms Who Underwent Bariatric Surgery
T. Mouillot, N. Rhyman, C. Gauthier, J. Paris +8 more
2020Obesity Surgery29 citations
Semantic Scholar
A simplified table using validated diagnostic criteria is effective to improve characterization of colorectal polyps: the CONECCT teaching program
M. Fabritius, Jean-Michel Gonzalez, A. Becq, X. Dray +16 more
2019Endoscopy International Open29 citations Open access
Semantic Scholar
Treatment, outcome, and prognostic factors in non-metastatic anal cancer: the French nationwide cohort study FFCD-ANABASE.
V. Vendrely, C. Lemanski, P. Pommier, K. Le Malicot +20 more
2023Radiotherapy and Oncology25 citations Open access
Semantic Scholar
Avelumab versus standard second line treatment chemotherapy in metastatic colorectal cancer patients with microsatellite instability: The SAMCO-PRODIGE 54 randomised phase II trial.
Julien Taïeb, T. André, F. El Hajbi, E. Barbier +12 more
2020Digestive and Liver Disease25 citations Open access
Semantic Scholar
Intra-arterial hepatic beads loaded with irinotecan (DEBIRI) with mFOLFOX6 in unresectable liver metastases from colorectal cancer: a Phase 2 study
S. Pernot, O. Pellerin, P. Artru, C. Montérymard +10 more
2020British Journal of Cancer22 citations Open access
Semantic Scholar
Carcinoembryonic Antigen Levels and Survival in Stage III Colon Cancer: Post hoc Analysis of the MOSAIC and PETACC-8 Trials
É. Auclin, J. Taieb, C. Lepage, T. Aparicio +13 more
2019Cancer Epidemiology, Biomarkers and Prevention22 citations Open access
Semantic Scholar
Non-metastatic colon cancer: French Intergroup Clinical Practice Guidelines for diagnosis, treatments, and follow-up (TNCD, SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, ACHBT, SFP, AFEF, and SFR).
T. Lecomte, D. Tougeron, R. Chautard, Diane Bressand +14 more
2024Digestive and Liver Disease21 citations Open access
Semantic Scholar
Impact of diabetes and metformin use on recurrence and outcome in stage II-III colon cancer patients-A pooled analysis of three adjuvant trials.
N. Christou, E. Bergen, C. Canton, K. Le Malicot +10 more
2022European Journal of Cancer21 citations Open access
Semantic Scholar
Lanreotide as maintenance therapy after first-line treatment in patients with non-resectable duodeno-pancreatic neuroendocrine tumours: An international double-blind, placebo-controlled randomised phase II trial - Prodige 31 REMINET: An FFCD study.
C. Lepage, J. Phelip, A. Lièvre, K. Le Malicot +15 more
2022European Journal of Cancer21 citations Open access
Semantic Scholar
Efficacy of treatments for VIPoma: A GTE multicentric series.
M. Brugel, T. Walter, B. Goichot, Denis Smith +6 more
2021Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]19 citations Open access
Semantic Scholar
FOLFIRINEC: a randomized phase II trial of mFOLFIRINOX vs platinum-etoposide for metastatic neuroendocrine carcinoma of gastroenteropancreatic or unknown origin.
J. Hadoux, P. Afchain, T. Walter, D. Tougeron +8 more
2021Digestive and Liver Disease19 citations Open access
Semantic Scholar
Gemcitabine plus nab-paclitaxel until progression or alternating with FOLFIRI.3, as first-line treatment for patients with metastatic pancreatic adenocarcinoma: The Federation Francophone de Cancérologie Digestive-PRODIGE 37 randomised phase II study (FIRGEMAX).
Y. Rinaldi, Anne-Laure Pointet, F. Khemissa-Akouz, K. Le Malicot +69 more
2020European Journal of Cancer19 citations Open access
Semantic Scholar
Liver transarterial chemoembolization and sunitinib for unresectable hepatocellular carcinoma: Results of the PRODIGE 16 study.
A. Turpin, T. de Baére, A. Heurgué, K. Le Malicot +17 more
2020Clinics And Research in Hepatology and Gastroenterology18 citations Open access
Semantic Scholar
Single-arm phase II trial to evaluate efficacy and tolerance of regorafenib monotherapy in patients over 70 with previously treated metastatic colorectal adenocarcinoma FFCD 1404 - REGOLD.
T. Aparicio, A. Darut‐Jouve, F. Khemissa-Akouz, C. Montérymard +18 more
2020Journal of Geriatric Oncology18 citations Open access
Semantic Scholar
Time to recurrence and its relation to survival after recurrence in patients resected for stage III colon cancer.
C. Rasola, P. Laurent-Puig, T. André, A. Falcoz +12 more
2023European Journal of Cancer16 citations Open access
Semantic Scholar
Postoperative circulating tumor DNA detection is associated with the risk of recurrence in patients resected for a stage II colorectal cancer
Adrien Grancher, L. Beaussire, S. Manfredi, K. Le Malicot +16 more
2022Frontiers in Oncology15 citations Open access
Semantic Scholar
Combination of CDX2 H-score quantitative analysis with CD3 AI-guided analysis identifies patients with a good prognosis only in stage III colon cancer.
V. Derangère, J. Lecuelle, C. Lepage, Oumaima Aoulad-Ben Salem +19 more
2022European Journal of Cancer15 citations Open access
Semantic Scholar
PRODIGE 59-DURIGAST trial: A randomised phase II study evaluating FOLFIRI + Durvalumab ± Tremelimumab in second-line of patients with advanced gastric cancer.
C. Evrard, C. Louvet, F. El Hajbi, F. Di Fiore +17 more
2020Digestive and Liver Disease15 citations Open access
Semantic Scholar
Anti-epidermal growth factor receptor therapy in combination with chemoradiotherapy for the treatment of locally advanced anal canal carcinoma: Results of a phase I dose-escalation study with panitumumab (FFCD 0904).
V. Vendrely, C. Lemanski, K. Gnep, E. Barbier +10 more
2019Radiotherapy and Oncology15 citations Open access
Semantic Scholar
FOLFIRI Plus Durvalumab With or Without Tremelimumab in Second-Line Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
D. Tougeron, L. Dahan, L. Evesque, K. Le Malicot +24 more
2024JAMA Oncology14 citations Open access
Semantic Scholar
Pembrolizumab with Capox Bevacizumab in patients with microsatellite stable metastatic colorectal cancer and a high immune infiltrate: The FFCD 1703-POCHI trial.
C. Gallois, J. Emile, Stefano Kim, C. Montérymard +19 more
2021Digestive and Liver Disease14 citations Open access
Semantic Scholar
Phase III randomized trial comparing systemic versus intra-arterial oxaliplatin, combined with LV5FU2 +/- irinotecan and a targeted therapy, in the first-line treatment of metastatic colorectal cancer restricted to the liver (OSCAR): PRODIGE 49.
S. Pernot, O. Pellerin, L. Mineur, C. Montérymard +14 more
2022Digestive and Liver Disease11 citations Open access
Semantic Scholar
MRI-Based Radiomics Input for Prediction of 2-Year Disease Recurrence in Anal Squamous Cell Carcinoma
N. Giraud, Olivier Saut, T. Aparicio, P. Ronchin +19 more
2021Cancers11 citations Open access
Semantic Scholar
Panitumumab in combination with chemoradiotherapy for the treatment of locally-advanced anal canal carcinoma: results of the FFCD 0904 phase II trial.
V. Vendrely, P. Ronchin, M. Minsat, K. Le Malicot +14 more
2023Radiotherapy and Oncology10 citations Open access
Semantic Scholar
Integrative Clinical and DNA Methylation Analyses in a Population-Based Cohort Identifies CDH17 and LRP2 as Risk Recurrence Factors in Stage II Colon Cancer
B. Tournier, Romain Aucagne, C. Truntzer, C. Fournier +8 more
2022Cancers10 citations Open access
Semantic Scholar
What is the optimal treatment for T1N0 anal squamous cell carcinoma? Analysis of current practices in the prospective French FFCD ANABASE cohort.
M. Bacci, L. Quéro, E. Barbier, L. Parrot +15 more
2021Digestive and Liver Disease10 citations Open access
Semantic Scholar
The area between ROC curves, a non‐parametric method to evaluate a biomarker for patient treatment selection
Yoann Blangero, M. Rabilloud, P. Laurent-Puig, K. Le Malicot +4 more
2020Biometrical journal. Biometrische Zeitschrift10 citations
Semantic Scholar
Management of digestive cancers during the COVID-19 second wave: A French intergroup point of view (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, ACHBT, SFR)
D. Tougeron, P. Michel, A. Lièvre, M. Ducreux +10 more
2020Digestive and Liver Disease10 citations Open access
Semantic Scholar
LBA23 Avelumab versus standard second-line treatment chemotherapy in metastatic colorectal cancer (mCRC) patients with microsatellite instability (MSI): The SAMCO-PRODIGE 54 randomised phase II trial
J. Taieb, O. Bouché, T. André, E. Barbier +14 more
2022Annals of Oncology9 citations Open access
Semantic Scholar
Management and Outcomes of Pancreatic Cancer in French Real-World Clinical Practice
V. Jooste, L. Bengrine-Lefevre, S. Manfredi, V. Quipourt +5 more
2022Cancers9 citations Open access
Semantic Scholar
Efficacy of donepezil for the treatment of oxaliplatin-induced peripheral neuropathy: DONEPEZOX, a protocol of a proof of concept, randomised, triple-blinded and multicentre trial
N. Kerckhove, D. Tougeron, C. Lepage, D. Pezet +4 more
2022BMC Cancer9 citations Open access
Semantic Scholar
Repeat Element Activation-Driven Inflammation: Role of NFκB and Implications in Normal Development and Cancer?
Baptiste Dumétier, Camille Sauter, Azadeh Hajmirza, Baptiste Pernon +8 more
2022Biomedicines9 citations Open access
Semantic Scholar
FFCD 1709-SIRTCI phase II trial: Selective internal radiation therapy plus Xelox, Bevacizumab and Atezolizumab in liver-dominant metastatic colorectal cancer.
V. Randrian, S. Pernot, K. Le Malicot, V. Catena +23 more
2022Digestive and Liver Disease8 citations Open access
Semantic Scholar
Observational Study in a Real-World Setting of Targeted Therapy in the Systemic Treatment of Progressive Unresectable or Metastatic Well-Differentiated Pancreatic Neuroendocrine Tumors (pNETs) in France: OPALINE Study
Denis Smith, C. Lepage, E. Vicaut, S. Dominguez +11 more
2022Advances in Therapy8 citations Open access
Semantic Scholar
Outcomes of anus squamous cell carcinoma. Management of anus squamous cell carcinoma and recurrences.
Imène Marref, G. Romain, V. Jooste, V. Vendrely +5 more
2021Digestive and Liver Disease8 citations Open access
Semantic Scholar
Loss of SMARCB1 expression in colon carcinoma
S. Melloul, J. Mosnier, J. Masliah-Planchon, C. Lepage +9 more
2020Cancer Biomarkers8 citations Open access
Semantic Scholar
Impact of G-CSF Prophylaxis on Chemotherapy Dose-Intensity, Link Between Dose-Intensity and Survival in Patients with Metastatic Pancreatic Adenocarcinoma
C. Canton, O. Boussari, M. Boulin, K. Le Malicot +5 more
2022The Oncologist7 citations Open access
Semantic Scholar
Safety of FOLFIRI + Durvalumab +/− Tremelimumab in Second Line of Patients with Advanced Gastric Cancer: A Safety Run-In from the Randomized Phase II Study DURIGAST PRODIGE 59
C. Evrard, T. Aparicio, É. Soularue, K. Le Malicot +7 more
2022Biomedicines7 citations Open access
Semantic Scholar
Practices and expectations on the use of circulating tumor DNA in colorectal cancer patients: a bi-national AGEO/AIOM/GERCOR/FFCD/FRENCH survey.
D. Basile, C. Gallois, F. Puglisi, R. Cohen +9 more
2021Clinics And Research in Hepatology and Gastroenterology7 citations Open access
Semantic Scholar
Effect of chemoprevention by low-dose aspirin of new or recurrent colorectal adenomas in patients with Lynch syndrome (AAS-Lynch): study protocol for a multicenter, double-blind, placebo-controlled randomized controlled trial
A. Soualy, D. Deutsch, Mourad Benallaoua, Amal Ait-Omar +73 more
2020Trials7 citations Open access
Semantic Scholar

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