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Torben Mentrup · SciRah

Researcher profile · Semantic Scholar

Torben Mentrup

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Torben Mentrup — researcher profile on SciRah

h-index: 14
Works: 29
Citations: 537

Most-cited papers

Small molecules intercept Notch signaling and the early secretory pathway.
Andreas Krämer, Torben Mentrup, Bertrand Kleizen, Eric Rivera‐Milla +10 more
2013Nature Chemical Biology58 citations
Semantic Scholar
Latest emerging functions of SPP/SPPL intramembrane proteases.
Torben Mentrup, R. Fluhrer, B. Schröder
2017European Journal of Cell Biology41 citations Open access
Semantic Scholar
The Intramembrane Proteases Signal Peptide Peptidase-Like 2a and 2b Have Distinct Functions In Vivo
Janna Schneppenheim, Susann Hüttl, Torben Mentrup, R. Lüllmann-rauch +10 more
2014Molecular and Cellular Biology39 citations Open access
Semantic Scholar
Physiological functions of SPP/SPPL intramembrane proteases
Torben Mentrup, Florencia Cabrera-Cabrera, R. Fluhrer, B. Schröder
2020Cellular and Molecular Life Sciences38 citations Open access
Semantic Scholar
The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban
Johannes Niemeyer, Torben Mentrup, Ronny Heidasch, Stephan A. Müller +16 more
2019EMBO Reports38 citations Open access
Semantic Scholar
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis
Torben Mentrup, K. Theodorou, Florencia Cabrera-Cabrera, Andreas O. Helbig +10 more
2019Journal of Experimental Medicine36 citations Open access
Semantic Scholar
Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis
Torben Mentrup, Anna Yamina Stumpff-Niggemann, N. Leinung, Christine Schlosser +15 more
2022Nature Communications34 citations Open access
Semantic Scholar
Signal peptide peptidase and SPP-like proteases - Possible therapeutic targets?
Torben Mentrup, A. Loock, R. Fluhrer, B. Schröder
2017Biochimica et biophysica acta. Molecular cell research31 citations Open access
Semantic Scholar
Signal peptide peptidase‐like 2c impairs vesicular transport and cleaves SNARE proteins
Alkmini A. Papadopoulou, Stephan A. Müller, Torben Mentrup, Merav D. Shmueli +8 more
2019EMBO Reports29 citations Open access
Semantic Scholar
Proteolytic Regulation of the Lectin-Like Oxidized Lipoprotein Receptor LOX-1
Torben Mentrup, Florencia Cabrera-Cabrera, B. Schröder
2021Frontiers in Cardiovascular Medicine28 citations Open access
Semantic Scholar
A Cell‐Based Assay Reveals Nuclear Translocation of Intracellular Domains Released by SPPL Proteases
Torben Mentrup, R. Häsler, R. Fluhrer, P. Saftig +1 more
2015Traffic : the International Journal of Intracellular Transport28 citations Open access
Semantic Scholar
Substrate determinants of signal peptide peptidase-like 2a (SPPL2a)-mediated intramembrane proteolysis of the invariant chain CD74.
Susann Hüttl, F. Helfrich, Torben Mentrup, Sebastian Held +5 more
2016Biochemical Journal26 citations Open access
Semantic Scholar
C11orf94/Frey is a key regulator for male fertility by controlling Izumo1 complex assembly
Whendy Contreras, Caroline Wiesehöfer, Dora Schreier, N. Leinung +5 more
2022Science Advances20 citations Open access
Semantic Scholar
Inhibition of cargo export at ER exit sites and the trans-Golgi network by the secretion inhibitor FLI-06
Y. Yonemura, Xiaolin Li, Katja Müller, Andreas Krämer +11 more
2016Journal of Cell Science19 citations Open access
Semantic Scholar
The intramembrane proteases SPPL2a and SPPL2b regulate the homeostasis of selected SNARE proteins
Moritz Ballin, Wolfram Griep, Mehul Patel, M. Karl +5 more
2022The FEBS Journal13 citations Open access
Semantic Scholar
Signal peptide peptidase-like 2 proteases: Regulatory switches or proteasome of the membrane?
Torben Mentrup, B. Schröder
2021Biochimica et biophysica acta. Molecular cell research12 citations Open access
Semantic Scholar
The role of SPP/SPPL intramembrane proteases in membrane protein homeostasis
Torben Mentrup, N. Leinung, Mehul Patel, R. Fluhrer +1 more
2023The FEBS Journal10 citations Open access
Semantic Scholar
Deficiency of the Intramembrane Protease SPPL2a Alters Antimycobacterial Cytokine Responses of Dendritic Cells.
Ann-Christine Gradtke, Torben Mentrup, Christian H. K. Lehmann, Florencia Cabrera-Cabrera +7 more
2020Journal of Immunology10 citations Open access
Semantic Scholar
Signal Peptide Peptidase-Like 2b Modulates the Amyloidogenic Pathway and exhibits an Aβ-dependent expression in Alzheimer's Disease.
Riccardo Maccioni, Caterina Travisan, Jack Badman, Stefania Zerial +13 more
2024Progress in neurobiology9 citations Open access
Semantic Scholar
Physiological shedding and C-terminal proteolytic processing of TMEM106B.
Sebastian Held, Christian Erck, S. Kemppainen, Florian Bleibaum +15 more
2024Cell Reports6 citations Open access
Semantic Scholar
Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
N. Leinung, Torben Mentrup, Mehul Patel, Thomas M. Gallagher +1 more
2023iScience5 citations Open access
Semantic Scholar
The DNase TREX1 is a substrate of the intramembrane protease SPP with implications for disease pathogenesis
Onur Kerem Tever, Torben Mentrup, I. Chinn, Hitoshi Ishikuma +6 more
2025Cellular and Molecular Life Sciences2 citations Open access
Semantic Scholar
Molecular and functional in vivo characterisation of murine Dectin‐1 isoforms
N. Leinung, Torben Mentrup, Sajma Hodzic, B. Schröder
2024European Journal of Immunology2 citations Open access
Semantic Scholar
The transmembrane domain of Frey1 harbors a transplantable inhibitory motif for intramembrane proteases
Whendy Contreras, J. Bazan, Torben Mentrup
2023Cellular and Molecular Life Sciences2 citations Open access
Semantic Scholar
Selective regulation of aspartyl intramembrane protease activity by calnexin
Whendy Contreras, J. Groenendyk, M. Gentzel, Pascal Y. Schönberg +4 more
2024Cellular and Molecular Life Sciences1 citations Open access
Semantic Scholar
Signal Peptide Peptidase-Like 2b affects APP cleavage and exhibits a biphasic Aβ-mediated expression in Alzheimer’s disease
Riccardo Maccioni, Caterina Travisan, Stefania Zerial, Annika Wagener +12 more
2022bioRxiv1 citations Open access
Semantic Scholar
A novel therapeutic approach to treat Alzheimer's disease: The brain‐specific signal peptide peptidase‐like 2b (SPPL2b)
S. Tambaro, Maccioni Riccardo, Stefania Zerial, Annika Wagener +5 more
2021Alzheimer's & Dementia0 citations
Semantic Scholar
Intramembrane protease SPP defines a cholesterol-regulated switch of the mevalonate pathway
Ronny Heidasch, Dönem Avci, C. Lüchtenborg, D. Kale +7 more
20210 citations
Semantic Scholar
Intramembrane proteases protect from atherosclerosis
Torben Mentrup, B. Schröder
2019Aging0 citations Open access
Semantic Scholar

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