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H. Khan · SciRah

Researcher profile · Semantic Scholar

H. Khan

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H. Khan — researcher profile on SciRah

h-index: 20
Works: 96
Citations: 1,541

Most-cited papers

A prooxidant mechanism for the anticancer and chemopreventive properties of plant polyphenols.
H. Khan, H. Zubair, M. Ullah, A. Ahmad +1 more
2012Current Drug Targets148 citations
Semantic Scholar
Soy isoflavone genistein induces cell death in breast cancer cells through mobilization of endogenous copper ions and generation of reactive oxygen species.
M. Ullah, A. Ahmad, H. Zubair, H. Khan +3 more
2011Molecular Nutrition & Food Research107 citations
Semantic Scholar
Plant polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer chemopreventive action.
H. Khan, H. Zubair, M. Faisal, M. Ullah +4 more
2014Molecular Nutrition & Food Research101 citations
Semantic Scholar
Effect of vitamins C and E on antioxidant status of breast‐cancer patients undergoing chemotherapy
N. Suhail, N. Bilal, H. Khan, S. Hasan +4 more
2012Journal of Clinical Pharmacy and Therapeutics101 citations Open access
Semantic Scholar
KRAS G12D targeted therapies for pancreatic cancer: Has the fortress been conquered?
S. Bannoura, H. Khan, A. Azmi
2022Frontiers in Oncology99 citations Open access
Semantic Scholar
Cancer Therapy by Catechins Involves Redox Cycling of Copper Ions and Generation of Reactive Oxygen Species
M. Farhan, H. Khan, Mohammad Oves, Ahmed Al-Harrasi +4 more
2016Toxins90 citations Open access
Semantic Scholar
Resveratrol Mobilizes Endogenous Copper in Human Peripheral Lymphocytes Leading to Oxidative DNA Breakage: A Putative Mechanism for Chemoprevention of Cancer
S. M. Hadi, M. Ullah, A. Azmi, A. Ahmad +3 more
2010Pharmaceutical Research85 citations
Semantic Scholar
The antioxidant ascorbic acid mobilizes nuclear copper leading to a prooxidant breakage of cellular DNA: implications for chemotherapeutic action against cancer
M. Ullah, H. Khan, H. Zubair, U. Shamim +1 more
2010Cancer Chemotherapy and Pharmacology69 citations
Semantic Scholar
Oral administration of copper to rats leads to increased lymphocyte cellular DNA degradation by dietary polyphenols: implications for a cancer preventive mechanism
H. Khan, H. Zubair, M. Ullah, A. Ahmad +1 more
2011Biometals56 citations
Semantic Scholar
The Prooxidant Action of Dietary Antioxidants Leading to Cellular DNA Breakage and Anticancer Effects: Implications for Chemotherapeutic Action Against Cancer
M. Ullah, A. Ahmad, H. Khan, H. Zubair +2 more
2011Cell Biochemistry and Biophysics49 citations
Semantic Scholar
Preclinical assessment with clinical validation of Selinexor with gemcitabine and nab-paclitaxel for the treatment of pancreatic ductal adenocarcinoma
A. Azmi, H. Khan, A. Aboukameel, I. Muqbil +11 more
2019Clinical Cancer Research44 citations Open access
Semantic Scholar
Targeting Nuclear Exporter Protein XPO1/CRM1 in Gastric Cancer
R. Sexton, Zaid Mahdi, R. Chaudhury, R. Beydoun +9 more
2019International Journal of Molecular Sciences42 citations Open access
Semantic Scholar
Calcium Release-Activated Calcium (CRAC) Channel Inhibition Suppresses Pancreatic Ductal Adenocarcinoma Cell Proliferation and Patient-Derived Tumor Growth
H. Khan, G. Mpilla, R. Sexton, S. Viswanadha +11 more
2020Cancers37 citations Open access
Semantic Scholar
Targeting XPO1 and PAK4 in 8505C Anaplastic Thyroid Cancer Cells: Putative Implications for Overcoming Lenvatinib Therapy Resistance
H. Khan, J. Ge, M. Nagasaka, A. Aboukameel +9 more
2019International Journal of Molecular Sciences35 citations Open access
Semantic Scholar
Mobilization of copper ions in human peripheral lymphocytes by catechins leading to oxidative DNA breakage: A structure activity study.
M. Farhan, A. Zafar, Sandesh Chibber, H. Khan +2 more
2015Archives of Biochemistry and Biophysics34 citations
Semantic Scholar
Connecting the Human Microbiome and Pancreatic Cancer
R. Sexton, M. H. Uddin, S. Bannoura, H. Khan +9 more
2022Cancer Metastasis Review28 citations Open access
Semantic Scholar
Mobilization of Intracellular Copper by Gossypol and Apogossypolone Leads to Reactive Oxygen Species-Mediated Cell Death: Putative Anticancer Mechanism
H. Zubair, S. Azim, H. Khan, M. Ullah +4 more
2016International Journal of Molecular Sciences26 citations Open access
Semantic Scholar
Inhibitor of the Nuclear Transport Protein XPO1 Enhances the Anticancer Efficacy of KRAS G12C Inhibitors in Preclinical Models of KRAS G12C–Mutant Cancers
H. Khan, M. Nagasaka, Yi-Wei Li, A. Aboukameel +14 more
2022bioRxiv24 citations Open access
Semantic Scholar
Synthesis of new boswellic acid derivatives as potential antiproliferative agents
Umair Shamraiz, H. Hussain, Najeeb Ur Rehman, S. Al-Shidhani +9 more
2019Natural Product Research23 citations Open access
Semantic Scholar
Apogossypolone, derivative of gossypol, mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage.
H. Zubair, H. Khan, M. Ullah, A. Ahmad +2 more
2012European Journal of Pharmaceutical Sciences23 citations
Semantic Scholar
Selinexor in combination with R-CHOP for frontline treatment of non-Hodgkin lymphoma: results of a phase 1 study
Erlene K Seymour, H. Khan, Yi-Wei Li, M. Chaker +19 more
2021Clinical Cancer Research20 citations Open access
Semantic Scholar
Prooxidant anticancer activity of plant-derived polyphenolic compounds: An underappreciated phenomenon
H. Khan, S. M. Hadi, R. Mohammad, A. Azmi
202019 citations
Semantic Scholar
Targeting Cellular Metabolism With CPI-613 Sensitizes Pancreatic Cancer Cells to Radiation Therapy
H. Khan, M. Kamgar, A. Aboukameel, S. Bannoura +8 more
2022Advances in Radiation Oncology18 citations Open access
Semantic Scholar
Molecular analysis of XPO1 inhibitor and gemcitabine–nab‐paclitaxel combination in KPC pancreatic cancer mouse model
M. H. Uddin, M. N. Al-Hallak, H. Khan, A. Aboukameel +15 more
2023Clinical and Translational Medicine17 citations Open access
Semantic Scholar
Two pyrolysate products from Omani frankincense smoke: First evidence of thermal aromatization of boswellic acids
A. Al-Harrasi, H. Hussain, J. Hussain, A. Al-Rawahi +7 more
201416 citations
Semantic Scholar
PAK4 and NAMPT as Novel Therapeutic Targets in Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, and Mantle Cell Lymphoma
H. Khan, M. H. Uddin, S. Balasubramanian, N. Sulaiman +9 more
2021Cancers15 citations Open access
Semantic Scholar
Synthesis of new triterpenic monomers and dimers as potential antiproliferative agents and their molecular docking studies.
Aasim Saeed, H. Hussain, Umair Shamraiz, Najeeb Ur Rehman +7 more
2018European journal of medicinal chemistry15 citations
Semantic Scholar
Bioactive chemical constituents from the resin of Aloe vera
Najeeb Ur Rehman, H. Hussain, M. Khiat, H. Khan +3 more
201715 citations
Semantic Scholar
Exacerbation of N-nitrosodiethylamine Induced Hepatotoxicity and DNA Damage in Mice Exposed to Chronic Unpredictable Stress
N. Bilal, N. Suhail, S. Hasan, G. M. Ashraf +5 more
2017Frontiers in Pharmacology13 citations Open access
Semantic Scholar
Simulating hypoxia-induced acidic environment in cancer cells facilitates mobilization and redox-cycling of genomic copper by daidzein leading to pro-oxidant cell death: implications for the sensitization of resistant hypoxic cancer cells to therapeutic challenges
M. F. Ullah, A. Ahmad, S. H. Bhat, H. Khan +3 more
2016Biometals13 citations
Semantic Scholar
Anti-proliferative and computational studies of two new pregnane glycosides from Desmidorchis flava.
M. Raees, H. Hussain, A. Al-Rawahi, R. Csuk +9 more
2016Bioorganic chemistry (Print)13 citations
Semantic Scholar
Desmiflavasides A and B: Two new bioactive pregnane glycosides from the sap of Desmidorchis flava
M. Raees, H. Hussain, Najeeb Ur Rehman, H. Khan +8 more
201513 citations
Semantic Scholar
Aloeverasides A and B: Two Bioactive C-Glucosyl Chromones from Aloe vera Resin
Najeeb Ur Rehman, H. Hussain, Mohammed Khiat, S. Al-Riyami +6 more
201612 citations
Semantic Scholar
Nizwaside: a new anticancer pregnane glycoside from the sap of Desmidorchis flava
H. Hussain, M. Raees, Najeeb Ur Rehman, A. Al-Rawahi +8 more
2015Archives of pharmacal research12 citations
Semantic Scholar
Nuclear Export Inhibitor KPT-8602 Synergizes with PARP Inhibitors in Escalating Apoptosis in Castration Resistant Cancer Cells
M. H. Uddin, Yi-Wei Li, H. Khan, I. Muqbil +7 more
2021International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Targeting guanine nucleotide exchange factors for novel cancer drug discovery
S. Bannoura, H. Khan, M. H. Uddin, R. Mohammad +2 more
2024Expert Opinion on Drug Discovery9 citations
Semantic Scholar
A norterpenoid and tripenoids from Commiphora mukul: isolation and biological activity
Najeeb Ur Rehman, H. Hussain, H. Khan, R. Csuk +3 more
20169 citations
Semantic Scholar
Pro-oxidant DNA breakage induced by the interaction of L-DOPA with Cu(II): a putative mechanism of neurotoxicity.
Asma Perveen, H. Khan, S. M. Hadi, G. Damanhouri +3 more
2015Advances in Experimental Medicine and Biology7 citations
Semantic Scholar
Abstract B077: KRASG12D inhibitor MRTX1133 synergizes with the next generation nuclear transport protein inhibitor eltanexor resulting in enhanced antitumor activity against pancreatic ductal adenocarcinoma
H. Khan, A. Aboukameel, M. H. Uddin, M. N. Al-Hallak +13 more
2024Cancer Research6 citations
Semantic Scholar
Roles of CRAC channel in cancer: implications for therapeutic development
H. Khan, Iqra Mazahir, Shriya C. Reddy, Farzeen M. Fazili +1 more
2020Expert Review of Precision Medicine and Drug Development6 citations Open access
Semantic Scholar
Anti-proliferative potential of cyclotetrapeptides from Bacillus velezensis RA5401 and their molecular docking on G-Protein-Coupled Receptors.
Najeeb Ur Rehman, R. M. M. Abed, H. Hussain, H. Khan +9 more
2018Microbial Pathogenesis6 citations
Semantic Scholar
The Clinical Menin Inhibitor Ziftomenib and the Nuclear Export Inhibitor Selinexor Synergistically Inhibit the Growth of MLL-r AML
M. H. Uddin, A. Aboukameel, S. Siddiqui, H. Khan +8 more
2023Blood5 citations
Semantic Scholar
Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRASG12C-Mutant Pancreatic and Lung Cancers
H. Khan, M. Nagasaka, A. Aboukameel, O. Alkhalili +16 more
2023Molecular Cancer Therapeutics5 citations Open access
Semantic Scholar
Anticancer efficacy of KRASG12C inhibitors is potentiated by PAK4 inhibitor KPT9274 in preclinical models of KRASG12C mutant pancreatic and lung cancers
H. Khan, M. Nagasaka, A. Aboukameel, O. Alkhalili +16 more
2023bioRxiv5 citations Open access
Semantic Scholar
Chemistry of Boswellic Acids and Other Terpenoids
A. Al-Harrasi, H. Hussain, R. Csuk, H. Khan
2019Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia4 citations
Semantic Scholar
Taxonomy of Boswellia Tree, Traditional Medicinal Uses of Frankincense and Historical Aspects of Boswellic Acids
A. Al-Harrasi, H. Hussain, R. Csuk, H. Khan
2019Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia4 citations
Semantic Scholar
Desmiflavanoside, a New Bioactive Flavonoid Glycoside Isolated from Desmidorchis flava
Najeeb Ur Rehman, H. Hussain, H. Khan, G. Abbas +2 more
2018Chemistry of Natural Compounds4 citations
Semantic Scholar
Molecular Characterization and Clinical Outcomes of Pancreatic Neuroendocrine Neoplasms Harboring PAK4-NAMPT Alterations
I. Azar, H. Khan, S. Bannoura, N. Gandhi +23 more
2025JCO oncology advances3 citations Open access
Semantic Scholar
Combined Use of Ziftomenib and Selinexor Is Effective in NPM1 Mutant Acute Myeloid Leukemia
Sandhya Dhiman, M. H. Uddin, Vikram Dhillon, J. Aguilar +12 more
2024Blood3 citations
Semantic Scholar
Regulator of Chromosome Condensation (RCC1) a novel therapeutic target in pancreatic ductal adenocarcinoma drives tumor progression via the c-Myc-RCC1-Ran axis
S. Bannoura, A. Aboukameel, H. Khan, M. H. Uddin +9 more
2023bioRxiv3 citations
Semantic Scholar

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A. Azmi×21
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A. Azmi — researcher profile on SciRah
A. Aboukameel×17
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M. H. Uddin×13
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M. H. Uddin — researcher profile on SciRah
H. Hussain×13
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H. Hussain — researcher profile on SciRah

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A. Al-Harrasi — researcher profile on SciRah

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Najeeb Ur Rehman×11

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Najeeb Ur Rehman — researcher profile on SciRah

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H. Zubair — researcher profile on SciRah

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A. Ahmad — researcher profile on SciRah

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S. M. Hadi — researcher profile on SciRah

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R. Mohammad — researcher profile on SciRah

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R. Csuk — researcher profile on SciRah