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Y. Shechter · SciRah

Researcher profile · Semantic Scholar

Y. Shechter

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Y. Shechter — researcher profile on SciRah

h-index: 43
Works: 140
Citations: 7,260

Most-cited papers

Oral administration of vanadate normalizes blood glucose levels in streptozotocin-treated rats. Characterization and mode of action.
J. Meyerovitch, Z. Farfel, J. Sack, Y. Shechter
1987Journal of Biological Chemistry405 citations Open access
Semantic Scholar
Insulin-Mimetic Effects of Vanadate: Possible Implications for Future Treatment of Diabetes
Y. Shechter
1990Diabetes356 citations
Semantic Scholar
Historic perspective and recent developments on the insulin-like actions of vanadium; toward developing vanadium-based drugs for diabetes
Y. Shechter, I. Goldwaser, M. Mironchik, M. Fridkin +1 more
2003204 citations
Semantic Scholar
Vanadate normalizes hyperglycemia in two mouse models of non-insulin-dependent diabetes mellitus.
J. Meyerovitch, Paul L. Rothenberg, Y. Shechter, S. Bonner-Weir +1 more
1991Journal of Clinical Investigation165 citations Open access
Semantic Scholar
Insulin-like effects of vanadium: basic and clinical implications.
I. Goldwaser, D. Gefel, E. Gershonov, M. Fridkin +1 more
2000Journal of Inorganic Biochemistry164 citations
Semantic Scholar
Insulinlike Effects of Zinc Ion in Vitro and in Vivo: Preferential Effects on Desensitized Adipocytes and Induction of Normoglycemia in Streptozocin-Induced Rats
A. Shisheva, D. Gefel, Y. Shechter
1992Diabetes138 citations
Semantic Scholar
Vanadium salts as insulin substitutes: mechanisms of action, a scientific and therapeutic tool in diabetes mellitus research.
N. Sekar, Jin-Ping Li, Y. Shechter
1996Critical reviews in biochemistry and molecular biology127 citations
Semantic Scholar
Quercetin selectively inhibits insulin receptor function in vitro and the bioresponses of insulin and insulinomimetic agents in rat adipocytes.
A. Shisheva, Y. Shechter
1992Biochemistry126 citations
Semantic Scholar
Role of cytosolic tyrosine kinase in mediating insulin-like actions of vanadate in rat adipocytes.
A. Shisheva, Y. Shechter
1993Journal of Biological Chemistry94 citations Open access
Semantic Scholar
Vanadium activates or inhibits receptor and non-receptor protein tyrosine kinases in cell-free experiments, depending on its oxidation state. Possible role of endogenous vanadium in controlling cellular protein tyrosine kinase activity.
G. Elberg, Jin-Ping Li, Y. Shechter
1994Journal of Biological Chemistry81 citations Open access
Semantic Scholar
Evidence for the distinct vanadyl(+4)-dependent activating system for manifesting insulin-like effects.
Jin-Ping Li, Gerard Elberg, Debbie C. Crans, Y. Shechter
1996Biochemistry79 citations
Semantic Scholar
Prolonging the Action of Protein and Peptide Drugs by a Novel Approach of Reversible Polyethylene Glycol Modification*
H. Tsubery, M. Mironchik, M. Fridkin, Y. Shechter
2004Journal of Biological Chemistry76 citations Open access
Semantic Scholar
Permolybdate and pertungstate--potent stimulators of insulin effects in rat adipocytes: mechanism of action.
Jin-Ping Li, G. Elberg, D. Gefel, Y. Shechter
1995Biochemistry74 citations
Semantic Scholar
Mechanism of pervanadate stimulation and potentiation of insulin-activated glucose transport in rat adipocytes: dissociation from vanadate effect.
A. Shisheva, Y. Shechter
1993Endocrinology70 citations
Semantic Scholar
Reversible PEGylation: a novel technology to release native interferon alpha2 over a prolonged time period.
T. Peleg-Shulman, H. Tsubery, M. Mironchik, M. Fridkin +2 more
2004Journal of Medicinal Chemistry65 citations
Semantic Scholar
Vanadate Activates Membranous Nonreceptor Protein Tyrosine Kinase in Rat Adipocytes
G. Elberg, Zhibin He, Jin-Ping Li, N. Sekar +1 more
1997Diabetes58 citations
Semantic Scholar
Reversible PEGylation of peptide YY3‐36 prolongs its inhibition of food intake in mice
Y. Shechter, H. Tsubery, M. Mironchik, M. Rubinstein +1 more
2005FEBS Letters57 citations
Semantic Scholar
Prolonging the half-life of human interferon-α2 in circulation: Design, preparation, and analysis of (2-sulfo-9-fluorenylmethoxycarbonyl)7- interferon-α2
Y. Shechter, L. Preciado-Patt, G. Schreiber, M. Fridkin
200157 citations Open access
Semantic Scholar
Glucose transport
S. Amir, Y. Shechter
1988Nature57 citations
Semantic Scholar
Angiotensin 1-7 as Means to Prevent the Metabolic Syndrome
Y. Marcus, G. Shefer, K. Sasson, F. Kohen +10 more
2013Diabetes52 citations Open access
Semantic Scholar
Hydrophobic carriers of vanadyl ions augment the insulinomimetic actions of vanadyl ions in rat adipocytes.
Y. Shechter, Assia Shisheva, R. Lazar, Jacqueline Libman +1 more
1992Biochemistry52 citations
Semantic Scholar
Antibodies to Insulin Receptor Followed by Anti-Idiotype: Antibodies to Insulin in Child With Hypoglycemia
D. Elias, I. Cohen, Y. Shechter, Z. Spirer +1 more
1987Diabetes50 citations
Semantic Scholar
The protein tyrosine phosphatase inhibitor, pervanadate, is a powerful antidiabetic agent in streptozotocin-treated diabetic rats.
Assia Shisheva, O. Ikonomov, Y. Shechter
1994Endocrinology48 citations
Semantic Scholar
Vanadium salts and the future treatment of diabetes.
Y. Shechter, Assia Shisheva
1993Endeavour43 citations
Semantic Scholar
A cytosolic protein tyrosine kinase in rat adipocytes
A. Shisheva, Y. Shechter
1992FEBS Letters43 citations Open access
Semantic Scholar
Vanadate stimulates in vivo glucose uptake in brain and arrests food intake and body weight gain in rats.
J. Meyerovitch, Y. Shechter, S. Amir
1989Physiology and Behavior43 citations
Semantic Scholar
Antilipolytic Actions of Vanadate and Insulin in Rat Adipocytes Mediated by Distinctly Different Mechanisms.
Jin-Ping Li, G. Elberg, N. Sekar, Zhibin He +1 more
1997Endocrinology39 citations Open access
Semantic Scholar
L-Glutamic acid gamma-monohydroxamate. A potentiator of vanadium-evoked glucose metabolism in vitro and in vivo.
Itzhak Goldwaser, Jin-Ping Li, E. Gershonov, M. Armoni +3 more
1999Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Reversible pegylation of insulin facilitates its prolonged action in vivo.
Y. Shechter, M. Mironchik, S. Rubinraut, H. Tsubery +3 more
2008European journal of pharmaceutics and biopharmaceutics37 citations
Semantic Scholar
Insulin-like actions of vanadate are mediated in an insulin-receptor-independent manner via non-receptor protein tyrosine kinases and protein phosphotyrosine phosphatases
Y. Shechter, Jingping Li, J. Meyerovitch, D. Gefel +4 more
1995Molecular and Cellular Biochemistry36 citations
Semantic Scholar
Non-receptor cytosolic protein tyrosine kinases from various rat tissues.
Gerard Elberg, Jin-Ping Li, Arthur Leibovitch, Y. Shechter
1995Biochimica et Biophysica Acta36 citations Open access
Semantic Scholar
Albumin-insulin conjugate releasing insulin slowly under physiological conditions: a new concept for long-acting insulin.
Y. Shechter, M. Mironchik, S. Rubinraut, A. Saul +2 more
2005Bioconjugate chemistry35 citations
Semantic Scholar
Organic vanadium chelators potentiate vanadium-evoked glucose metabolism in vitro and in vivo: establishing criteria for optimal chelators.
I. Goldwaser, S. Qian, E. Gershonov, M. Fridkin +1 more
2000Molecular Pharmacology35 citations
Semantic Scholar
Turning low-molecular-weight drugs into prolonged acting prodrugs by reversible pegylation: a study with gentamicin.
Yonit Marcus, K. Sasson, M. Fridkin, Y. Shechter
2008Journal of Medicinal Chemistry29 citations
Semantic Scholar
A novel approach for a water-soluble long-acting insulin prodrug: design, preparation, and analysis of [(2-sulfo)-9-fluorenylmethoxycarbonyl](3)-insulin.
E. Gershonov, I. Goldwaser, M. Fridkin, Y. Shechter
2000Journal of Medicinal Chemistry29 citations
Semantic Scholar
Insulin Mimetic Effects of Vanadium
Y. Shechter, J. Meyerovitch, Z. Farfel, J. Sack +5 more
199029 citations
Semantic Scholar
New concept for long-acting insulin: spontaneous conversion of an inactive modified insulin to the active hormone in circulation: 9-fluorenylmethoxycarbonyl derivative of insulin.
E. Gershonov, Y. Shechter, M. Fridkin
1999Diabetes28 citations
Semantic Scholar
Peptide Derived from HIV-1 TAT Protein Destabilizes a Monolayer of Endothelial Cells in an in Vitro Model of the Blood-Brain Barrier and Allows Permeation of High Molecular Weight Proteins*
I. Cooper, K. Sasson, V. Teichberg, M. Schnaider-Beeri +2 more
2012Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Combined Local Blood–Brain Barrier Opening and Systemic Methotrexate for the Treatment of Brain Tumors
I. Cooper, D. Last, D. Guez, S. Sharabi +10 more
2015Journal of Cerebral Blood Flow and Metabolism25 citations Open access
Semantic Scholar
Vanadate restores glucose 6-phosphate in diabetic rats: a mechanism to enhance glucose metabolism.
Qian Sun, N. Sekar, I. Goldwaser, E. Gershonov +2 more
2000American Journal of Physiology. Endocrinology and Metabolism25 citations
Semantic Scholar
Independent signal-transduction pathways for vanadate and for insulin in the activation of glycogen synthase and glycogenesis in rat adipocytes.
N. Sekar, Jin-Ping Li, Ze-Bin He, D. Gefel +1 more
1999Endocrinology25 citations Open access
Semantic Scholar
Phenylarsine oxide and vanadate: apparent paradox of inhibition of protein phosphotyrosine phosphatases in rat adipocytes.
Jin-Ping Li, G. Elberg, Y. Shechter
1996Biochimica et Biophysica Acta24 citations Open access
Semantic Scholar
New Technologies to Prolong Life-time of Peptide and Protein Drugs In vivo
Y. Shechter, M. Mironchik, A. Saul, E. Gershonov +9 more
2007International Journal of Peptide Research and Therapeutics23 citations
Semantic Scholar
Reversible pegylation prolongs the hypotensive effect of atrial natriuretic peptide.
M. Nesher, Y. Vachutinsky, G. Fridkin, Y. Schwarz +4 more
2008Bioconjugate chemistry22 citations
Semantic Scholar
Vanadate inhibits glucose output from isolated perfused rat liver
R. Bruck, H. Prigozin, Z. Krepel, P. Rotenberg +2 more
1991Hepatology22 citations
Semantic Scholar
Prolonging the half-life of human interferon-alpha 2 in circulation: Design, preparation, and analysis of (2-sulfo-9-fluorenylmethoxycarbonyl)7- interferon-alpha 2.
Y. Shechter, Liana Preciado-Patt, G. Schreiber, M. Fridkin
2001Proceedings of the National Academy of Sciences of the United States of America19 citations
Semantic Scholar
Delivery of neuropeptides from the periphery to the brain: studies with enkephalin.
Y. Shechter, E. Heldman, K. Sasson, Tzach Bachar +2 more
2010ACS Chemical Neuroscience18 citations Open access
Semantic Scholar
Polymyxin B is an inhibitor of insulin-induced hypoglycemia in the whole animal model. Studies on the mode of inhibitory action.
S. Amir, S. Sasson, N. Kaiser, J. Meyerovitch +1 more
1987Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Involvement of a protein kinase C and protein phosphatases in adhesion of CD4+ T cells to and detachment from extracellular matrix proteins.
S. Miron, R. Hershkoviz, Iris Tirosh, Y. Shechter +2 more
1992Cellular Immunology17 citations
Semantic Scholar
Centrally mediated hypoglycemic effect of insulin: apparent involvement of specific insulin receptors.
S. Amir, Y. Shechter
1987Brain Research17 citations
Semantic Scholar

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M. Fridkin×12
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M. Fridkin — researcher profile on SciRah
Jin-Ping Li×10
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Jin-Ping Li — researcher profile on SciRah
M. Fridkin×8
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M. Fridkin — researcher profile on SciRah
M. Mironchik×7
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E. Gershonov — researcher profile on SciRah

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J. Meyerovitch×6

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J. Meyerovitch — researcher profile on SciRah

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A. Shisheva — researcher profile on SciRah

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G. Elberg — researcher profile on SciRah

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H. Tsubery — researcher profile on SciRah

I. Goldwaser×5

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N. Sekar — researcher profile on SciRah