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T. Louie · SciRah

Researcher profile · Semantic Scholar

T. Louie

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T. Louie — researcher profile on SciRah

h-index: 21
Works: 40
Citations: 6,774

Most-cited papers

The Genome of the Kinetoplastid Parasite, Leishmania major
A. Ivens, C. Peacock, Elizabeth A. Worthey, L. Murphy +97 more
2005Science1,423 citations Open access
Semantic Scholar
The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease
Najib M. A. el-Sayed, P. Myler, D. Bartholomeu, D. Nilsson +78 more
2005Science1,409 citations Open access
Semantic Scholar
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
M. Feitosa, A. Kraja, D. Chasman, Yun J. Sung +269 more
2018PLoS ONE764 citations Open access
Semantic Scholar
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
A. Mahajan, C. Spracklen, Wei-Hua Zhang, M. Ng +345 more
2022Nature Genetics616 citations Open access
Semantic Scholar
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
Ken Suzuki, K. Hatzikotoulas, L. Southam, H. Taylor +360 more
2024Nature540 citations Open access
Semantic Scholar
Discovery of common and rare genetic risk variants for colorectal cancer
J. Huyghe, S. Bien, T. Harrison, H. Kang +195 more
2018Nature Genetics479 citations Open access
Semantic Scholar
The Trans-Ancestral Genomic Architecture of Glycemic Traits
Ji Chen, C. Spracklen, G. Marenne, Arushi Varshney +404 more
2021Nature Genetics465 citations Open access
Semantic Scholar
Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis
M. Emond, T. Louie, J. Emerson, Wei Zhao +10 more
2012Nature Genetics236 citations Open access
Semantic Scholar
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
Yun J. Sung, T. Winkler, L. de las Fuentes, Amy R. Bentley +293 more
2018American Journal of Human Genetics134 citations Open access
Semantic Scholar
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Amy R. Bentley, Yun J. Sung, Michael R. Brown, T. Winkler +298 more
2019Nature Genetics122 citations Open access
Semantic Scholar
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
P. D. de Vries, Michael R. Brown, Amy R. Bentley, Yun J. Sung +262 more
2019112 citations
Semantic Scholar
Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload
Christine E. McLaren, M. Emond, V. Subramaniam, P. Phatak +12 more
2015Hepatology79 citations Open access
Semantic Scholar
Whole-exome Sequencing Identifies Rare Variants in ATP8B4 as a Risk Factor for Systemic Sclerosis
Li Gao, M. Emond, T. Louie, C. Cheadle +14 more
2016Arthritis & Rheumatology46 citations Open access
Semantic Scholar
Admixture mapping identifies novel loci for obstructive sleep apnea in Hispanic/Latino Americans
He-Ming Wang, B. Cade, T. Sofer, S. Sands +39 more
2018Human Molecular Genetics44 citations Open access
Semantic Scholar
Exome Sequencing of Phenotypic Extremes Identifies CAV2 and TMC6 as Interacting Modifiers of Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis
M. Emond, T. Louie, J. Emerson, Jessica X. Chong +9 more
2015PLoS Genetics44 citations Open access
Semantic Scholar
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
Yun J. Sung, L. de las Fuentes, T. Winkler, D. Chasman +277 more
2019Human Molecular Genetics39 citations Open access
Semantic Scholar
Genome‐wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?
L. Raffield, T. Louie, T. Sofer, D. Jain +16 more
2017Human Molecular Genetics32 citations Open access
Semantic Scholar
Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep
B. Cade, Han Chen, A. Stilp, T. Louie +43 more
2019PLoS Genetics31 citations Open access
Semantic Scholar
The Epithelial Sodium Channel Is a Modifier of the Long‐Term Nonprogressive Phenotype Associated with F508del CFTR Mutations
Pankaj B. Agrawal, Ruo-Bing Wang, Hongmei Li, K. Schmitz-Abe +14 more
2017American Journal of Respiratory Cell and Molecular Biology29 citations Open access
Semantic Scholar
Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications
Ken Suzuki, K. Hatzikotoulas, L. Southam, H. Taylor +347 more
2023medRxiv27 citations Open access
Semantic Scholar
Genome-Wide Association Study of Heavy Smoking and Daily/Nondaily Smoking in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
N. Saccone, L. Emery, T. Sofer, S. Gogarten +24 more
2018Nicotine & Tobacco Research27 citations Open access
Semantic Scholar
A Genome-Wide Association Study Identifies Blood Disorder–Related Variants Influencing Hemoglobin A1c With Implications for Glycemic Status in U.S. Hispanics/Latinos
Jee-Young Moon, T. Louie, D. Jain, T. Sofer +21 more
2019Diabetes Care18 citations Open access
Semantic Scholar
Variation in Cilia Protein Genes and Progression of Lung Disease in Cystic Fibrosis
E. Blue, T. Louie, Jessica X. Chong, S. Hebbring +6 more
2018Annals of the American Thoracic Society16 citations Open access
Semantic Scholar
Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons.
S. Khoury, Qiao-Ping Wang, M. Parisien, Pavel Gris +21 more
2020Sleep13 citations Open access
Semantic Scholar
GWAS of QRS duration identifies new loci specific to Hispanic/Latino populations
Brenton R. Swenson, T. Louie, Henry J. Lin, Raúl Méndez-Giráldez +26 more
2018bioRxiv12 citations Open access
Semantic Scholar
Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries
A. Huerta-Chagoya, Joohyun Kim, R. Mandla, Ying-Chang Lu +254 more
2025medRxiv9 citations
Semantic Scholar
Genetic variation near IRS1 is associated with adiposity and a favorable metabolic profile in US Hispanics/Latinos
Q. Qi, S. Gogarten, L. Emery, T. Louie +9 more
2016Obesity8 citations Open access
Semantic Scholar
Multi-ancestry genome-wide analysis identifies shared genetic effects and common genetic variants for self-reported sleep duration.
Ben H Scammell, Cynthia Tchio, Yanwei Song, T. Nishiyama +14 more
2023Human Molecular Genetics7 citations Open access
Semantic Scholar
Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits
Lauren E. Petty, Hung-Hsin Chen, Elizabeth G. Frankel, Wan-Ying Zhu +88 more
2025Nature Communications6 citations Open access
Semantic Scholar
Correction: Exome Sequencing of Phenotypic Extremes Identifies CAV2 and TMC6 as Interacting Modifiers of Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis
M. Emond, T. Louie, J. Emerson, Jessica X. Chong +9 more
2015PLoS Genetics2 citations Open access
Semantic Scholar
Exome Sequencing Identifies a GNPAT Variant Associated with Severe Iron Overload in HFE C282Y Homozygous Men with Extreme Phenotypes; Possible Role in Regulation of Hepcidin Expression
G. Mclaren, M. Emond, V. Subramaniam, P. Phatak +12 more
20141 citations
Semantic Scholar
Exome Sequencing Identifies Genes and Variant Alleles Associated With Severity Of Iron Overload In Hemochromatosis HFE C282Y Homozygotes
C. McLaren, M. Emond, P. Phatak, P. Adams +10 more
20131 citations
Semantic Scholar
Multi-ancestry genome-wide analysis identifies common genetic variants for self-reported sleep duration and shared genetic effects
Ben H Scammell, Yanwei Song, Cynthia Tchio, T. Nishiyama +14 more
2022bioRxiv0 citations Open access
Semantic Scholar
Feitosa, M. F., & Levy, D. (2018). Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K
M. Feitosa, A. Kraja, D. Chasman, Yun J. Sung +214 more
20180 citations
Semantic Scholar
Genome wide association study of sleep quality identifies a new association with loci near MPP6
S. Khoury, M. Parisien, Q.-P. Wang, G. Neely +14 more
20170 citations
Semantic Scholar
Exome Sequencing in Hfe C282Y Homozygotes with Extreme Hepatic Iron Overload Reveals Modifying Genes for the Development of Cirrhosis
M. Emond, C. McLaren, T. Louie, Jie Wu +13 more
20160 citations
Semantic Scholar
Association of CAV2 and TMC6 variants with lung function.
M. Emond, T. Louie, J. Emerson, Jessica X. Chong +9 more
20150 citations Open access
Semantic Scholar
Power to discover TMC6 with aSKAT-O for a test of size α under the actual ages of the individuals in the extreme samples in this study.
M. Emond, T. Louie, J. Emerson, Jessica X. Chong +9 more
20150 citations Open access
Semantic Scholar
Primary results for CAV2 from exome discovery and validation phases.
M. Emond, T. Louie, J. Emerson, Jessica X. Chong +9 more
20150 citations Open access
Semantic Scholar
The Genome Sequence of Trypanosoma cruzi , Etiologic Agent of Chagas Disease
Najib M. A. el-Sayed, P. Myler, D. Bartholomeu, D. Nilsson +78 more
19990 citations
Semantic Scholar

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