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Secil Koseoglu · SciRah

Researcher profile · Semantic Scholar

Secil Koseoglu

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Secil Koseoglu — researcher profile on SciRah

h-index: 12
Works: 35
Citations: 552

Most-cited papers

Advances in platelet granule biology
Secil Koseoglu, R. Flaumenhaft
2013Current opinion in hematology74 citations
Semantic Scholar
CD73 inhibits cGAS-STING and cooperates with CD39 to promote pancreatic cancer
C. Jacoberger-Foissac, Isabelle Cousineau, Y. Bareche, D. Allard +16 more
2022Cancer immunology research67 citations Open access
Semantic Scholar
VAMP-7 links granule exocytosis to actin reorganization during platelet activation.
Secil Koseoglu, Christian G Peters, Jennifer L. Fitch-Tewfik, Omozuanvbo R. Aisiku +3 more
2015Blood57 citations Open access
Semantic Scholar
Fluorous Polymeric Membranes for Ionophore-Based Ion-Selective Potentiometry: How Inert is Teflon AF?
Chun-Ze Lai, Secil Koseoglu, E. Lugert, P. Boswell +3 more
2009Journal of the American Chemical Society53 citations Open access
Semantic Scholar
Bioanalytical tools for single-cell study of exocytosis
Shencheng Ge, Secil Koseoglu, C. Haynes
2010Analytical and Bioanalytical Chemistry51 citations
Semantic Scholar
Dynamin-related protein-1 controls fusion pore dynamics during platelet granule exocytosis
Secil Koseoglu, J. Dilks, Christian G Peters, J. Fitch +5 more
2013Arteriosclerosis, Thrombosis and Vascular Biology47 citations Open access
Semantic Scholar
Electroanalytical Eavesdropping on Single Cell Communication
Donghyuk Kim, Secil Koseoglu, Benjamin M Manning, Audrey F. Meyer +1 more
2011Analytical Chemistry32 citations Open access
Semantic Scholar
Analytical Characterization of the Role of Phospholipids in Platelet Adhesion and Secretion
Secil Koseoglu, Audrey F. Meyer, Donghyuk Kim, Ben M. Meyer +3 more
2014Analytical Chemistry24 citations Open access
Semantic Scholar
Cholesterol effects on vesicle pools in chromaffin cells revealed by carbon-fiber microelectrode amperometry
Secil Koseoglu, S. Love, C. Haynes
2011Analytical and Bioanalytical Chemistry23 citations
Semantic Scholar
SRF617 Is a Potent Inhibitor of CD39 with Immunomodulatory and Antitumor Properties
M. C. Warren, Stephan J. Matissek, M. Rausch, M. Panduro +18 more
2023ImmunoHorizons21 citations Open access
Semantic Scholar
Platelet Membrane Variations and their Effects on δ-Granule Secretion Kinetics and Aggregation Spreading among Different Species
Sarah M. Gruba, Secil Koseoglu, Audrey F. Meyer, Ben M. Meyer +2 more
2015Biochimica et Biophysica Acta15 citations Open access
Semantic Scholar
Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody–Drug Conjugate in Patient-derived Xenografts
Adnan O. Abu-Yousif, D. Cvet, M. Gallery, Bret Bannerman +17 more
2020Molecular Cancer Therapeutics12 citations Open access
Semantic Scholar
First-in-human phase I/II trial evaluating BNT142, a first-in-class mRNA encoded, bispecific antibody targeting Claudin 6 (CLDN6) and CD3, in patients (pts) with CLDN6-positive advanced solid tumors.
T. Yap, A. Hernando-Calvo, E. Calvo, V. Moreno +16 more
2025Journal of Clinical Oncology11 citations Open access
Semantic Scholar
Response Mechanism of Ion-Selective Electrodes Based on a Guanidine Ionophore: An Apparently ‘Two-Thirds Nernstian’ Response Slope
Secil Koseoglu, Chun-Ze Lai, C. Ferguson, P. Bühlmann
200810 citations
Semantic Scholar
A phase I/II dose escalation and expansion trial to evaluate safety and preliminary efficacy of BNT141 in patients with claudin-18.2-positive solid tumors.
K. Papadopoulos, M. Tehfé, A. A. Abdul Razak, S. Pant +16 more
2023Journal of Clinical Oncology8 citations Open access
Semantic Scholar
A phase I/II dose escalation trial with expansion cohorts to evaluate safety and preliminary efficacy of BNT142 in patients with prospectively confirmed claudin 6-positive solid tumors.
T. Yap, K. Papadopoulos, E. Garralda, A. Spira +16 more
2023Journal of Clinical Oncology8 citations
Semantic Scholar
PRE-CLINICAL DEVELOPMENT OF TNFR2 LIGAND-BLOCKING BI-1808 FOR CANCER IMMUNOTHERAPY
L. Mårtensson, Mathilda Kovacek, P. Holmkvist, M. Semmrich +18 more
20208 citations
Semantic Scholar
Abstract B120: TAK-164, a GCC-targeted antibody-drug conjugate (ADC) for the treatment of colorectal cancers and other GI malignancies
Adnan O. Abu-Yousif, Bret Bannerman, D. Cvet, M. Gallery +12 more
20188 citations
Semantic Scholar
Abstract 6639: SRF617, a potent enzymatic inhibitor of CD39, demonstrates single-agent activity and cooperates with various cancer therapies in both solid tumor and hematologic malignancies
S. Das, A. Dulak, G. Tan, Marc O. Johnson +10 more
2020Immunology5 citations
Semantic Scholar
Stimulated Platelets but Not Endothelium Generate Thrombin Via a Factor XIIa-Dependent Mechanism Requiring Phosphatidylserine Exposure
Pavan K. Bendapudi, K. De Ceunynck, Secil Koseoglu, R. Bekendam +3 more
20165 citations
Semantic Scholar
Isotope-dilution UPLC-MS/MS determination of cell-secreted bioactive lipids.
Audrey F. Meyer, J. W. Thompson, Yiwen Wang, Secil Koseoglu +2 more
2013In Analysis4 citations
Semantic Scholar
Abstract 648: Activity of BNT327/PM8002 (PD-L1 x VEGF-A bispecific antibody) in combination with BNT325/DB-1305 (TROP2 ADC) in solid tumors: Early preclinical and clinical evidence to support BNT327 + ADC combinations
E. Hamilton, Jianqing Zhu, W. Zhuang, Ying Cheng +24 more
2025Cancer Research3 citations
Semantic Scholar
A global phase III, double-blind, randomized trial of BNT327/PM8002 plus chemotherapy (chemo) compared to atezolizumab plus chemo in patients (pts) with first-line (1L) extensive-stage small cell lung cancer (ES-SCLC).
Martin Reck, J. Heymach, K. Franks, C. Gay +14 more
2025Journal of Clinical Oncology3 citations
Semantic Scholar
Platelet Drp1 phosphorylation provides a platform for immune-based platelet function testing
David A. Barrios, Shi-Hui Guo, Matthew Powers, Secil Koseoglu +11 more
2026Blood2 citations
Semantic Scholar
Abstract 1802: CD39 inhibition shapes the transcriptional landscape of myeloid cells and induces proinflammatory states in the CT26 syngeneic tumor model
Devapregasan Moodley, Mayra S. Carneiro, Sonia D. Gas, A. Dulak +10 more
2021Immunology1 citations
Semantic Scholar
727 Increased serum levels of EBI3 are associated with poor outcome in hepatocellular carcinoma patients and SRF388, a first-in-class IL-27 blocking antibody, inhibits the growth of murine liver tumors
M. Rausch, Devapregasan Moodley, Marisa O. Peluso, Secil Koseoglu +10 more
2020Journal for ImmunoTherapy of Cancer1 citations Open access
Semantic Scholar
Stereochemistry- and concentration-dependent effects of phosphatidylserine enrichment on platelet function.
Audrey F. Meyer, Sarah M. Gruba, Donghyuk Kim, Ben M. Meyer +3 more
2017Biochimica et Biophysica Acta - Biomembranes1 citations Open access
Semantic Scholar
Dynamin-Related Protein-1 Controls Fusion Pore Dynamics During Platelet Granule Secretion and Thrombus Formation In Vivo
R. Flaumenhaft, Secil Koseoglu, J. Dilks, Christian G Peters +3 more
20111 citations
Semantic Scholar
PB1231 Platelet Drp1 phosphorylation provides a platform for immune-based platelet function testing
David A. Barrios, Shi-Hui Guo, Matthew Powers, Secil Koseoglu +11 more
2026Research and Practice in Thrombosis and Haemostasis0 citations Open access
Semantic Scholar
PP01.123: A Global Phase 3, Double-Blind, Randomized Trial of Pumitamig (BNT327/BMS986545; PD-L1 × VEGF-A bsAb) Plus Chemotherapy Compared to Atezolizumab Plus Chemotherapy in Patients with First-Line (1L) Extensive-Stage Small Cell Lung Cancer (ES-SCLC) - ROSETTA Lung-01
M. Reck, J. Heymach, K. Franks, C. Gay +12 more
2026Journal of Thoracic Oncology0 citations
Semantic Scholar
Abstract 1607: IL-27 signaling serves as an immunological checkpoint for NK cells to promote hepatocellular carcinoma in multiple murine models
T. Aghayev, Aleksandra M Mazitova, M. Rausch, Kerry F White +11 more
2021Immunology0 citations
Semantic Scholar
247 The fully human antibody SRF617 is a potent inhibitor of ecto-enzyme CD39 in vivo
Stephan J. Matissek, Marisella Panduro Sicheva, Secil Koseoglu, Ricard Masia +8 more
2021Journal for ImmunoTherapy of Cancer0 citations Open access
Semantic Scholar
OPINION Advances in platelet granule biology
Secil Koseoglu, R. Flaumenhaft
20130 citations
Semantic Scholar
Exploring the Fundamentals of Platelet Granular Storage and Secretion at the Single
Secil Koseoglu
20130 citations
Semantic Scholar
Understanding the Fundamentals of Platelet Granular Storage and Release at Single Cell Level
Secil Koseoglu, C. Haynes
20110 citations Open access
Semantic Scholar

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