Adam Roth

Most-cited papers

Control of gene expression by a natural metabolite-responsive ribozyme
W. C. Winkler, A. Nahvi, Adam Roth, J. Collins +1 more
2004Nature892 citations
Semantic Scholar
The Structural and Functional Diversity of Metabolite-binding Riboswitches
Adam Roth, R. Breaker
2009Annual Review of Biochemistry553 citations Open access
Semantic Scholar
New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control.
Jeffrey E. Barrick, Keith A. Corbino, W. C. Winkler, A. Nahvi +8 more
2004Proceedings of the National Academy of Sciences of the United States of America490 citations Open access
Semantic Scholar
Widespread Genetic Switches and Toxicity Resistance Proteins for Fluoride
Jenny L. Baker, Narasimhan Sudarsan, Z. Weinberg, Adam Roth +2 more
2011Science441 citations Open access
Semantic Scholar
Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline
Z. Weinberg, Jeffrey E. Barrick, Z. Yao, Adam Roth +10 more
2007Nucleic Acids Research316 citations Open access
Semantic Scholar
Tandem Riboswitch Architectures Exhibit Complex Gene Control Functions
Narasimhan Sudarsan, M. Hammond, Kirsten F. Block, R. Welz +3 more
2006Science267 citations
Semantic Scholar
A riboswitch selective for the queuosine precursor preQ1 contains an unusually small aptamer domain
Adam Roth, W. C. Winkler, E. E. Regulski, Bobby W. K. Lee +8 more
2007Nature Structural &Molecular Biology248 citations
Semantic Scholar
A widespread self-cleaving ribozyme class is revealed by bioinformatics
Adam Roth, Z. Weinberg, Andy G. Y. Chen, P. B. Kim +2 more
2013Nature Chemical Biology231 citations Open access
Semantic Scholar
An amino acid as a cofactor for a catalytic polynucleotide.
Adam Roth, Ronald R. Breaker
1998Proceedings of the National Academy of Sciences of the United States of America203 citations Open access
Semantic Scholar
Ribozyme speed limits.
Gail Mitchell Emilsson, S. Nakamura, Adam Roth, R. Breaker
2003RNA: A publication of the RNA Society199 citations Open access
Semantic Scholar
Identification of Hammerhead Ribozymes in All Domains of Life Reveals Novel Structural Variations
Jonathan Perreault, Z. Weinberg, Adam Roth, O. Popescu +3 more
2011PLoS Comput. Biol.159 citations Open access
Semantic Scholar
Guanine riboswitch variants from Mesoplasma florum selectively recognize 2′-deoxyguanosine
Jane N. Kim, Adam Roth, R. Breaker
2007Proceedings of the National Academy of Sciences of the United States of America156 citations Open access
Semantic Scholar
Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions
Z. Weinberg, Christina E. Lünse, Keith A. Corbino, T. Ames +5 more
2017Nucleic Acids Research144 citations Open access
Semantic Scholar
A common speed limit for RNA-cleaving ribozymes and deoxyribozymes.
R. Breaker, Gail Mitchell Emilsson, Denis Lazarev, S. Nakamura +3 more
2003RNA: A publication of the RNA Society120 citations Open access
Semantic Scholar
Confirmation of a second natural preQ1 aptamer class in Streptococcaceae bacteria.
M. Meyer, Adam Roth, Stephanie M. Chervin, G. A. Garcia +1 more
2008RNA: A publication of the RNA Society116 citations Open access
Semantic Scholar
New families of human regulatory RNA structures identified by comparative analysis of vertebrate genomes.
B. Parker, I. Moltke, Adam Roth, Stefan Washietl +4 more
2011Genome Research113 citations Open access
Semantic Scholar
Characteristics of the glmS ribozyme suggest only structural roles for divalent metal ions.
Adam Roth, A. Nahvi, Mark Lee, Inbal Jona +1 more
2006RNA: A publication of the RNA Society108 citations Open access
Semantic Scholar
Challenges of ligand identification for riboswitch candidates
M. Meyer, M. Hammond, Yasmmyn D Salinas, Adam Roth +2 more
2011RNA Biology72 citations Open access
Semantic Scholar
An expanded collection and refined consensus model of glmS ribozymes.
P. McCown, Adam Roth, R. Breaker
2011RNA: A publication of the RNA Society60 citations Open access
Semantic Scholar
Characteristics of ligand recognition by a glmS self-cleaving ribozyme.
Jinsoo Lim, Beth C Grove, Adam Roth, R. Breaker
2006Angewandte Chemie52 citations
Semantic Scholar
Identification of a large noncoding RNA in extremophilic eubacteria
Elena Puerta-Fernández, Jeffrey E. Barrick, Adam Roth, R. Breaker
2006Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
Biochemical Validation of a Fourth Guanidine Riboswitch Class in Bacteria
Hubert Salvail, Aparaajita Balaji, Diane Yu, Adam Roth +1 more
2020bioRxiv40 citations Open access
Semantic Scholar
Variants of the guanine riboswitch class exhibit altered ligand specificities for xanthine, guanine, or 2′-deoxyguanosine
Siddhartha Hamal Dhakal, S. S. Panchapakesan, P. Slattery, Adam Roth +1 more
2022Proceedings of the National Academy of Sciences of the United States of America33 citations Open access
Semantic Scholar
Selection in vitro of allosteric ribozymes.
Adam Roth, R. Breaker
2004Methods in molecular biology22 citations
Semantic Scholar
Conserved sequences associated with myriad antibiotic resistance genes are integron components and not aminoglycoside riboswitches
Adam Roth, R. Breaker
2013Cell20 citations Open access
Semantic Scholar
Natural circularly permuted group II introns in bacteria produce RNA circles
Adam Roth, Z. Weinberg, Koen Vanderschuren, M. Murdock +1 more
2021iScience17 citations Open access
Semantic Scholar
8-oxoguanine riboswitches in bacteria detect and respond to oxidative DNA damage
Siddhartha Hamal Dhakal, K. Kavita, S. S. Panchapakesan, Adam Roth +1 more
2023Proceedings of the National Academy of Sciences of the United States of America11 citations Open access
Semantic Scholar
Genetic disruption of the bacterial raiA motif noncoding RNA causes defects in sporulation and aggregation
L. W. Soares, Christopher G King, Chrishan M Fernando, Adam Roth +1 more
2024Proceedings of the National Academy of Sciences of the United States of America10 citations Open access
Semantic Scholar
A spermidine riboswitch class in bacteria exploits a close variant of an aptamer for the enzyme cofactor S-adenosylmethionine
Hubert Salvail, Aparaajita Balaji, Adam Roth, Ronald R. Breaker
2023Cell Reports10 citations Open access
Semantic Scholar
Ribozyme Discovery in Bacteria
Adam Roth, Ronald R. Breaker
2021Ribozymes0 citations
Semantic Scholar
Riboswitches: Natural Metabolite‐binding RNAs Controlling Gene Expression
Adam Roth, R. Welz, R. Breaker
20060 citations
Semantic Scholar