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F. Mathews · SciRah

Researcher profile · Semantic Scholar

F. Mathews

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F. Mathews — researcher profile on SciRah

h-index: 48
Works: 258
Citations: 14K

Most-cited papers

Structural identification of the pathway of long-range communication in an allosteric enzyme
P. Gandhi, Zhiwei Chen, F. Mathews, E. Di Cera
2008Proceedings of the National Academy of Sciences of the United States of America109 citations Open access
Semantic Scholar
A Novel, Potent Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase
L. de Garavilla, M. Greco, N. Sukumar, Zhi-Wei Chen +13 more
2005Journal of Biological Chemistry86 citations Open access
Semantic Scholar
Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4
Alaji Bah, Zhiwei Chen, Leslie A. Bush-Pelc, F. Mathews +1 more
2007Proceedings of the National Academy of Sciences of the United States of America72 citations Open access
Semantic Scholar
Probing Oxygen Activation Sites in Two Flavoprotein Oxidases Using Chloride as an Oxygen Surrogate
Phaneeswara-Rao Kommoju, Zhi-Wei Chen, R. Bruckner, F. Mathews +1 more
2011Biochemistry67 citations Open access
Semantic Scholar
Crystal structure of human intrinsic factor: Cobalamin complex at 2.6-Å resolution
F. Mathews, M. Gordon, Zhi-Wei Chen, K. Rajashankar +3 more
2007Proceedings of the National Academy of Sciences of the United States of America60 citations Open access
Semantic Scholar
The Anticoagulant Thrombin Mutant W215A/E217A Has a Collapsed Primary Specificity Pocket*
A. Pineda, Zhi-Wei Chen, S. Caccia, Angelene M. Cantwell +4 more
2004Journal of Biological Chemistry57 citations Open access
Semantic Scholar
Energetic and Structural Consequences of Perturbing Gly-193 in the Oxyanion Hole of Serine Proteases*
Kevin M. Bobofchak, A. Pineda, F. Mathews, E. Di Cera
2005Journal of Biological Chemistry56 citations Open access
Semantic Scholar
Crystal structure of thrombin in complex with fibrinogen gamma' peptide.
A. Pineda, Zhi-Wei Chen, Francesca Marino, F. Mathews +2 more
2006Biophysical Chemistry52 citations
Semantic Scholar
Crystal Structure of Thrombin in a Self-inhibited Conformation*
A. Pineda, Zhi-Wei Chen, Alaji Bah, Laura C. Garvey +2 more
2006Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Thrombin Functions through Its RGD Sequence in a Non-canonical Conformation*
Matthew E. Papaconstantinou, C. J. Carrell, A. Pineda, Kevin M. Bobofchak +5 more
2005Journal of Biological Chemistry40 citations Open access
Semantic Scholar
A joint x-ray and neutron study on amicyanin reveals the role of protein dynamics in electron transfer
N. Sukumar, F. Mathews, Paul A. Langan, V. Davidson
2010Proceedings of the National Academy of Sciences of the United States of America37 citations Open access
Semantic Scholar
Structural Characterization of Mutations at the Oxygen Activation Site in Monomeric Sarcosine Oxidase
M. Jorns, Zhi-Wei Chen, F. Mathews
2010Biochemistry31 citations Open access
Semantic Scholar
Important Role of the Cys-191–Cys-220 Disulfide Bond in Thrombin Function and Allostery*
Leslie A. Bush-Pelc, Francesca Marino, Zhiwei Chen, A. Pineda +2 more
2007Journal of Biological Chemistry31 citations Open access
Semantic Scholar
Heterotetrameric sarcosine oxidase: structure of a diflavin metalloenzyme at 1.85 A resolution.
Zhi-Wei Chen, A. Hassan-Abdulah, Gouhua Zhao, M. Jorns +1 more
2006Journal of Molecular Biology31 citations
Semantic Scholar
p-Cresol methylhydroxylase: alteration of the structure of the flavoprotein subunit upon its binding to the cytochrome subunit.
L. Cunane, Zhi-Wei Chen, W. Mcintire, F. Mathews
2005Biochemistry31 citations
Semantic Scholar
Crystal structure of an electron transfer complex between aromatic amine dehydrogenase and azurin from Alcaligenes faecalis.
N. Sukumar, Zhi-Wei Chen, D. Ferrari, A. Merli +5 more
2006Biochemistry30 citations
Semantic Scholar
Structure of the sodium borohydride-reduced N-(cyclopropyl)glycine adduct of the flavoenzyme monomeric sarcosine oxidase.
Zhi-Wei Chen, Gouhua Zhao, S. Martinović, M. Jorns +1 more
2005Biochemistry27 citations
Semantic Scholar
Structural studies of two mutants of amicyanin from Paracoccus denitrificans that stabilize the reduced state of the copper.
C. J. Carrell, Dapeng Sun, Shou-Lei Jiang, V. Davidson +1 more
2004Biochemistry26 citations
Semantic Scholar
Generation of novel copper sites by mutation of the axial ligand of amicyanin. Atomic resolution structures and spectroscopic properties.
C. J. Carrell, John K Ma, W. Antholine, J. Hosler +2 more
2007Biochemistry24 citations
Semantic Scholar
NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: structures of closed and open forms at 1.15 and 1.90 A resolution.
C. J. Carrell, R. Bruckner, David Venci, Gouhua Zhao +2 more
2007Structure21 citations Open access
Semantic Scholar
High Resolution Structures of an Oxidized and Reduced Flavoprotein
N. Sukumar, A. Dewanti, Bharati Mitra, F. Mathews
2004Journal of Biological Chemistry20 citations Open access
Semantic Scholar
High resolution crystal structures of free thrombin in the presence of K(+) reveal the molecular basis of monovalent cation selectivity and an inactive slow form.
C. J. Carrell, Leslie A. Bush, F. Mathews, E. Di Cera
2006Biophysical Chemistry19 citations
Semantic Scholar
High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Implications for inhibitor specificity and drug design.
Zhi-Wei Chen, C. Vignaud, A. Jaafar, Bernard I. Levy +4 more
2012Biochimie18 citations
Semantic Scholar
Structural Basis of Na+ Activation Mimicry in Murine Thrombin*
Francesca Marino, Zhi-Wei Chen, C. E. Ergenekan, Leslie A. Bush-Pelc +2 more
2007Journal of Biological Chemistry18 citations Open access
Semantic Scholar
The enzymatic reaction-induced configuration change of the prosthetic group PQQ of methanol dehydrogenase.
Jie Li, Jian-Gang Gan, F. Mathews, Z. Xia
2011Biochemical and Biophysical Research Communications - BBRC15 citations
Semantic Scholar
Arginine 49 is a bifunctional residue important in catalysis and biosynthesis of monomeric sarcosine oxidase: a context-sensitive model for the electrostatic impact of arginine to lysine mutations.
Alshaimaa Hassan-Abdallah, Guo-Hua Zhao, Zhi-Wei Chen, F. Mathews +1 more
2008Biochemistry15 citations
Semantic Scholar
A single methionine residue dictates the kinetic mechanism of interprotein electron transfer from methylamine dehydrogenase to amicyanin.
John K Ma, Yongting Wang, C. J. Carrell, F. Mathews +1 more
2007Biochemistry15 citations
Semantic Scholar
Cloning, expression and crystallization of heterotetrameric sarcosine oxidase from Pseudomonas maltophilia.
Alshaimaa Hassan-Abdallah, Guo-Hua Zhao, M. Eschenbrenner, Zhi-Wei Chen +2 more
2005Protein Expression and Purification15 citations Open access
Semantic Scholar
Mutation at a Strictly-Conserved, Active-Site Tyrosine in the Copper Amine Oxidase Leads to Uncontrolled Oxygenase Activity
Zhi-Wei Chen, S. Datta, J. DuBois, Judith P. Klinman +1 more
2010Biochemistry14 citations Open access
Semantic Scholar
Site-directed mutagenesis of proline 94 to alanine in amicyanin converts a true electron transfer reaction into one that is kinetically coupled.
Dapeng Sun, Xiang-Hui Li, F. Mathews, V. Davidson
2005Biochemistry11 citations
Semantic Scholar
Structures of the G81A mutant form of the active chimera of (S)-mandelate dehydrogenase and its complex with two of its substrates.
N. Sukumar, A. Dewanti, A. Merli, G. Rossi +2 more
2009Acta Crystallographica Section D: Biological Crystallography10 citations Open access
Semantic Scholar
Electron transfer in crystals of the binary and ternary complexes of methylamine dehydrogenase with amicyanin and cytochrome c551i as detected by EPR spectroscopy
D. Ferrari, M. Di Valentin, D. Carbonera, A. Merli +4 more
2004JBIC Journal of Biological Inorganic Chemistry10 citations
Semantic Scholar
Correlation of rhombic distortion of the type 1 copper site of M98Q amicyanin with increased electron transfer reorganization energy.
John K Ma, F. Mathews, V. Davidson
2007Biochemistry9 citations Open access
Semantic Scholar
A preliminary time-of-flight neutron diffraction study on amicyanin from Paracoccus denitrificans.
N. Sukumar, P. Langan, F. Mathews, L. H. Jones +3 more
2005Acta Crystallographica Section D: Biological Crystallography9 citations
Semantic Scholar
Proline96 of the copper ligand loop of amicyanin regulates electron transfer from methylamine dehydrogenase by positioning other residues at the protein-protein interface
Moonsung Choi, N. Sukumar, F. Mathews, Aimin Liu +1 more
2011Biochemistry8 citations Open access
Semantic Scholar
Site-directed mutagenesis of proline 52 to glycine in amicyanin converts a true electron transfer reaction into one that is conformationally gated.
John K Ma, C. J. Carrell, F. Mathews, V. Davidson
2006Biochemistry7 citations
Semantic Scholar
b‐Type Cytochrome Electron Carriers: Cytochromes b562 and b5, and Flavocytochrome b2
F. Mathews
20067 citations
Semantic Scholar
Structure of the monotopic membrane protein (S)-mandelate dehydrogenase at 2.2Å resolution
N. Sukumar, Shixuan Liu, Wei-Kai Li, F. Mathews +2 more
2018Biochimie6 citations Open access
Semantic Scholar
High Resolution Structures of an Oxidized and Reduced Flavoprotein THE WATER SWITCH IN A SOLUBLE FORM OF (S)-MANDELATE DEHYDROGENASE*
N. Sukumar, A. Dewanti, Bharati Mitra, F. Mathews
20045 citations
Semantic Scholar
Factors that Affect Oxygen Activation and Coupling of the Two Redox Cycles in the Aromatization Reaction Catalyzed by NikD, an Unusual Amino Acid Oxidase
Phaneeswara-Rao Kommoju, R. Bruckner, Patricia Ferreira, C. J. Carrell +2 more
2009Biochemistry4 citations Open access
Semantic Scholar
Identification of a stable flavin-thiolate adduct in heterotetrameric sarcosine oxidase.
R. Hynson, F. Mathews, Marilyn Schuman Jorns
2006Journal of Molecular Biology4 citations Open access
Semantic Scholar
Crystal and molecular structure of tert. ‐butyloxycarbonyl‐L‐prolyl‐α‐aminoisobutyryl‐L‐alanyl‐α‐aminoisobutyrate methyl ester
P. van Roey, G. D. Smith, T. M. Balasubramanian, E. W. Czerwinski +2 more
20093 citations
Semantic Scholar
Crystal structure of glucose oxidase for space group P3121 at 1.3 A resolution.
Phaneeswara-Rao Kommoju, Zhi-Wei Chen, R. Bruckner, F. Mathews +1 more
20112 citations
Semantic Scholar
Postcrystallization Analysis of the Irreproducibility of the Human Intrinsic Factor—Cobalamin Complex Crystals
N. Sukumar, F. Mathews, M. Gordon, S. Ealick +1 more
2009Crystal Growth & Design1 citations Open access
Semantic Scholar
Structure of the blue copper protein Amicyanin to 0.75 A resolution
C. J. Carrell, V. Davidson, Z. Chen, L. Cunane +2 more
20071 citations
Semantic Scholar
Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution.
Z.-W. Chen, P. Trickey, M. Jorns, F. Mathews
20071 citations
Semantic Scholar
Crystal structure of murine thrombin in complex with the extracellular fragment of murine PAR4
Alaji Bah, Zhi-Wei Chen, Leslie A. Bush-Pelc, F. Mathews +1 more
20071 citations
Semantic Scholar
Structural comparison of the oxidized ternary electron transfer complex of methylamine dehydrogenase, amicyanin and cytochrome c551i from Paracoccus denitrificans with the substrate-reduced, copper free complex at 1.9 A resolution.
Zhi-Wei Chen, R. Durley, V. Davidson, F. Mathews
20061 citations
Semantic Scholar
Molecular cloning and structural analysis of quinohemoprotein alcohol dehydrogenase ADHIIG from Pseudomonas putida HK5. Compariison to the other quinohemoprotein alcohol dehydrogenase ADHIIB found in the same microorganism.
H. Toyama, Zhi-Wei Chen, M. Fukumoto, O. Adachi +2 more
20051 citations
Semantic Scholar
Crystal structure of the anticoagulant thrombin mutant W215A/E217A bound to PPACK
A. Pineda, Zhi-Wei Chen, S. Caccia, S. Savvides +3 more
20041 citations
Semantic Scholar

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