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B. Ksander · SciRah

Researcher profile · Semantic Scholar

B. Ksander

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B. Ksander — researcher profile on SciRah

h-index: 41
Works: 207
Citations: 6,275

Most-cited papers

Reprogramming to recover youthful epigenetic information and restore vision
Yuancheng Ryan Lu, B. Brommer, Xiao Tian, A. Krishnan +25 more
2020Nature710 citations Open access
Semantic Scholar
Loss of epigenetic information as a cause of mammalian aging
Jae-Hyun Yang, Motoshi Hayano, Patrick T. Griffin, João A. Amorim +60 more
2023Cell583 citations
Semantic Scholar
NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration.
W. Tseng, Thuzar Thein, K. Kinnunen, K. Lashkari +3 more
2013Investigative Ophthalmology and Visual Science289 citations Open access
Semantic Scholar
ABCB5 is a limbal stem cell gene required for corneal development and repair
B. Ksander, P. Kolovou, Brian J. Wilson, Karim R. Saab +19 more
2014Nature266 citations Open access
Semantic Scholar
Retinal microglia initiate neuroinflammation in ocular autoimmunity
Y. Okunuki, Ryo Mukai, Takeshi Nakao, Steven J. Tabor +4 more
2019Proceedings of the National Academy of Sciences of the United States of America184 citations Open access
Semantic Scholar
Microglia inhibit photoreceptor cell death and regulate immune cell infiltration in response to retinal detachment
Y. Okunuki, Ryo Mukai, E. Pearsall, Garrett Klokman +8 more
2018Proceedings of the National Academy of Sciences of the United States of America149 citations Open access
Semantic Scholar
A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing GPCR-initiated mitogenic signals
J. Vaqué, R. Dorsam, Xiao-Dong Feng, R. Iglesias-Bartolome +7 more
2012Molecules and Cells137 citations Open access
Semantic Scholar
Uveal Melanoma Cell Lines: Where do they come from? (An American Ophthalmological Society Thesis).
M. Jager, J. Magner, B. Ksander, S. Dubovy
2016Transactions of the American Ophthalmological Society101 citations
Semantic Scholar
Opposing Roles for Membrane Bound and Soluble Fas Ligand in Glaucoma-Associated Retinal Ganglion Cell Death
M. Gregory, C. Hackett, Emma Abernathy, Karen S. Lee +12 more
2011PLoS ONE97 citations Open access
Semantic Scholar
Tumor Cell Programmed Death Ligand 1-Mediated T Cell Suppression Is Overcome by Coexpression of CD80
Samuel T. Haile, J. Bosch, Nnenna I. Agu, Annette M. Zeender +6 more
2011Journal of Immunology93 citations Open access
Semantic Scholar
Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions
A. Zahr, P. Alcaide, Jin-Ling Yang, Alexander Jones +10 more
2016Nature Communications84 citations Open access
Semantic Scholar
αB-Crystallin Protects Retinal Tissue during Staphylococcus aureus- Induced Endophthalmitis
E. Whiston, N. Sugi, M. Kamradt, C. Sack +6 more
2008Infection and Immunity73 citations Open access
Semantic Scholar
Soluble Guanylate Cyclase α1–Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma
E. Buys, Yu-Chieh Ko, C. Alt, Sarah R. Hayton +26 more
2013PLoS ONE62 citations Open access
Semantic Scholar
Overexpression of soluble Fas ligand following AAV gene therapy prevents retinal ganglion cell death in chronic and acute murine models of glaucoma
A. Krishnan, F. Fei, Alexander Jones, P. Busto +3 more
2016Journal of Immunology57 citations Open access
Semantic Scholar
Regulation of intraocular pressure by soluble and membrane guanylate cyclases and their role in glaucoma
E. Buys, L. Potter, L. Pasquale, B. Ksander
2014Frontiers in Molecular Neuroscience52 citations Open access
Semantic Scholar
The absence of invariant chain in MHC II cancer vaccines enhances the activation of tumor-reactive type 1 CD4+ T lymphocytes
J. Thompson, M. Srivastava, J. Bosch, V. Clements +2 more
2008Cancer Immunology and Immunotherapy48 citations Open access
Semantic Scholar
DNA Break-Induced Epigenetic Drift as a Cause of Mammalian Aging
Motoshi Hayano, Jae-Hyun Yang, M. Bonkowski, João A. Amorim +37 more
2019bioRxiv37 citations Open access
Semantic Scholar
Retinoblastoma cells are inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP‐dependent kinase
S. Theodoropoulou, P. Kolovou, Y. Morizane, M. Kayama +5 more
2010The FASEB Journal36 citations Open access
Semantic Scholar
Repairing the corneal epithelium using limbal stem cells or alternative cell-based therapies
Y. Sasamoto, B. Ksander, M. Frank, N. Frank
2018Expert Opinion on Biological Therapy34 citations Open access
Semantic Scholar
LOCAL TREATMENT WITH ALPHA-MELANOCYTE STIMULATING HORMONE REDUCES CORNEAL ALLOREJECTION
P. Hamrah, Z. Haskova, A. Taylor, Qiang Zhang +2 more
2009Transplantation32 citations Open access
Semantic Scholar
Process development and safety evaluation of ABCB5+ limbal stem cells as advanced-therapy medicinal product to treat limbal stem cell deficiency
Alexandra Norrick, Jasmina Esterlechner, E. Niebergall-Roth, Ulf Dehio +16 more
2020Stem cell research & therapeutics30 citations Open access
Semantic Scholar
Uveal melanoma cell-based vaccines express MHC II molecules that traffic via the endocytic and secretory pathways and activate CD8+ cytotoxic, tumor-specific T cells
J. Bosch, U. Iheagwara, S. Reid, M. Srivastava +4 more
2009Cancer Immunology and Immunotherapy26 citations Open access
Semantic Scholar
Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming
Yuancheng Ryan Lu, A. Krishnan, B. Brommer, Xiao Tian +22 more
2019bioRxiv22 citations Open access
Semantic Scholar
A Novel Model of Metastatic Conjunctival Melanoma in Immune-Competent Mice.
S. Schlereth, Sandra Iden, M. Mescher, B. Ksander +3 more
2015Investigative Ophthalmology and Visual Science21 citations Open access
Semantic Scholar
A Murine Model for Metastatic Conjunctival Melanoma.
Nadine E. de Waard, Jinfeng Cao, S. McGuire, P. Kolovou +3 more
2015Investigative Ophthalmology and Visual Science20 citations
Semantic Scholar
Limbal BCAM expression identifies a proliferative progenitor population capable of holoclone formation and corneal differentiation
Y. Sasamoto, Catherine A. A. Lee, Brian J. Wilson, Florian Buerger +12 more
2022Cell Reports18 citations Open access
Semantic Scholar
Proceedings of the Association for Research in Vision and Ophthalmology and Champalimaud Foundation Ocular Oncogenesis and Oncology Conference
Justine R. Smith, J. Pe'er, R. Belfort, F. Cardoso +21 more
2019Translational Vision Science & Technology18 citations Open access
Semantic Scholar
Soluble Fas ligand blocks destructive corneal inflammation in mouse models of corneal epithelial debridement and LPS induced keratitis
M. Gregory-Ksander, Victor L. Perez, A. Marshak-Rothstein, B. Ksander
2019Experimental Eye Research15 citations
Semantic Scholar
Investigation of factors associated with ABCB5-positive limbal stem cell isolation yields from human donors
Y. Sasamoto, Naoko Sasamoto, Johnathan Tran, Ananda Mishra +3 more
2019The ocular surface15 citations Open access
Semantic Scholar
Expression of Multidrug Resistance Transporter ABCB5 in a Murine Model of Human Conjunctival Melanoma
Nadine E. de Waard, P. Kolovou, S. McGuire, Jinfeng Cao +4 more
2015Ocular Oncology and Pathology15 citations Open access
Semantic Scholar
Increased Resistance to Staphylococcus aureus Endophthalmitis in BALB/c Mice: Fas Ligand Is Required for Resolution of Inflammation but Not for Bacterial Clearance
N. Sugi, E. Whiston, B. Ksander, M. Gregory
2013Infection and Immunity14 citations Open access
Semantic Scholar
Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities
Shinya Watanabe, R. Hayashi, Y. Sasamoto, M. Tsujikawa +5 more
2021iScience11 citations Open access
Semantic Scholar
Spontaneous bacterial keratitis in CD36 knockout mice.
J. Klocke, R. Bárcia, S. Heimer, E. Cario +4 more
2011Investigative Ophthalmology and Visual Science11 citations Open access
Semantic Scholar
Epigenetic Regulation of Corneal Epithelial Differentiation by TET2
Y. Sasamoto, Si-Yuan Wu, Catherine A. Lee, Jason Y. Jiang +3 more
2023International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
ABCB5+ Limbal Epithelial Stem Cells Inhibit Developmental but Promote Inflammatory (Lymph) Angiogenesis While Preventing Corneal Inflammation
Berbang Meshko, Thomas L A Volatier, Karina Hadrian, Shuya Deng +8 more
2023Cells10 citations Open access
Semantic Scholar
Midkine promotes metastasis and therapeutic resistance via mTOR/RPS6 in uveal melanoma.
M. Karg, L. John, Nasrin Refaian, Christian Buettner +8 more
2022Molecular Cancer Research10 citations Open access
Semantic Scholar
HLA Class I Antigen Expression in Conjunctival Melanoma Is Not Associated With PD-L1/PD-1 Status.
Jinfeng Cao, N. J. Brouwer, E. Jordanova, M. Marinkovic +7 more
2018Investigative Ophthalmology and Visual Science10 citations Open access
Semantic Scholar
Vascular normalization: A novel method for inhibiting vascular leakage in age-related macular degeneration
Adarsha Koirala, A. Rothstein, B. Ksander, M. Gregory-Ksander
201510 citations
Semantic Scholar
Integrin-linked kinase regulates senescence in an Rb-dependent manner in cancer cell lines
Rose Duminuco, Jake W. Noble, Joseph Goody, Manju Sharma +4 more
2015Cell Cycle10 citations Open access
Semantic Scholar
Uveal melanoma cell growth is inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase.
Ahmad Al-Moujahed, Fotini Nicolaou, K. Brodowska, T. Papakostas +5 more
2014Investigative Ophthalmology and Visual Science10 citations Open access
Semantic Scholar
RB116: An RB1+ retinoblastoma cell line expressing primitive markers
A. Bejjani, Meerim Choi, L. Cassidy, David W. Collins +4 more
2012Molecular Vision9 citations
Semantic Scholar
Opposing Roles of Blood-Borne Monocytes and Tissue-Resident Macrophages in Limbal Stem Cell Damage after Ocular Injury
Cheng-Xin Zhou, F. Lei, M. Mittermaier, B. Ksander +5 more
2021bioRxiv5 citations Open access
Semantic Scholar
Process Development and Safety Evaluation of ABCB5+ Limbal Stem Cells as Advanced-therapy Medicinal Product to Treat Limbal Stem Cell De ciency
Alexandra Norrick, N. Frank, G. Auffarth, B. Ksander +2 more
20205 citations
Semantic Scholar
Destructive neuroinflammation triggered by activation of the NLRP3 inflammasome in the glaucomatous optic nerve head
M. Gregory-Ksander, F. Fei, A. Krishnan, T. Tzeng +4 more
20174 citations
Semantic Scholar
Reversal of aging-induced and glaucoma-induced vision loss by in vivo epigenetic reprogramming
B. Ksander, Yuancheng Ryan Lu, A. Krishnan, B. Brommer +10 more
20202 citations
Semantic Scholar
In vitro expanded human purified ABCB5-positive limbal stem cells for treatment of limbal stem cell deficiency.
B. Ksander, E. Korobkina, C. Ganss, A. Kluth +2 more
20182 citations
Semantic Scholar
Soluble Fas ligand provides long-term protection in a chronic mouse model of glaucoma by inhibiting glial activation, inflammation, and apoptosis
M. Gregory-Ksander, F. Fei, A. Marshak-Rothstein, B. Ksander +1 more
20162 citations
Semantic Scholar
Gene therapy treatment with AAV-soluble Fas ligand protects retinal ganglion cells during development of Glaucoma
A. Krishnan, F. Fei, Alexander Jones, B. Ksander +2 more
20152 citations
Semantic Scholar
Preventing glaucoma by blocking activation of the NLRP3 inflammasome in the optic nerve head
F. Fei, A. Krishnan, A. Rothstein, B. Ksander +1 more
20152 citations
Semantic Scholar
Targeting Genetic Aberrations in Uveal Melanoma
S. Woodman, B. C. Hayes, K. Stemke-Hale, Michelle D. Williams +4 more
20102 citations
Semantic Scholar

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