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E. Tramontano · SciRah

Researcher profile · Semantic Scholar

E. Tramontano

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E. Tramontano — researcher profile on SciRah

h-index: 42
Works: 283
Citations: 5,757

Most-cited papers

Structural and Biochemical Analysis of the Dual Inhibition of MG-132 against SARS-CoV-2 Main Protease (Mpro/3CLpro) and Human Cathepsin-L
E. Costanzi, M. Kuzikov, F. Esposito, Simone Albani +7 more
2021International Journal of Molecular Sciences82 citations Open access
Semantic Scholar
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities
A. Corona, Krzysztof Wycisk, C. Talarico, C. Manelfi +10 more
2022ACS Pharmacology & Translational Science77 citations Open access
Semantic Scholar
Quercetin Blocks Ebola Virus Infection by Counteracting the VP24 Interferon-Inhibitory Function
Elisa Fanunza, M. Iampietro, S. Distinto, A. Corona +4 more
2020Antimicrobial Agents and Chemotherapy51 citations Open access
Semantic Scholar
Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2
Elisa Fanunza, F. Carletti, M. Quartu, Nicole Grandi +6 more
2021Virulence44 citations Open access
Semantic Scholar
Retrotransposons as Drivers of Mammalian Brain Evolution
R. Ferrari, Nicole Grandi, E. Tramontano, G. Dieci
2021Life39 citations Open access
Semantic Scholar
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds
C. Sanna, A. Marengo, S. Acquadro, Alessia Caredda +5 more
2021Plants32 citations Open access
Semantic Scholar
INMI1 Zika Virus NS4B Antagonizes the Interferon Signaling by Suppressing STAT1 Phosphorylation
Elisa Fanunza, Nicole Grandi, M. Quartu, F. Carletti +6 more
2021Viruses31 citations Open access
Semantic Scholar
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort
A. Zaliani, Laura Vangeel, Jeanette Reinshagen, Daniela Iaconis +22 more
2022Scientific Data29 citations Open access
Semantic Scholar
Natural and Nature-Derived Products Targeting Human Coronaviruses
K. Vougogiannopoulou, A. Corona, E. Tramontano, Michael N. Alexis +1 more
2021Molecules26 citations Open access
Semantic Scholar
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity
Maria Giulia Nizi, L. Persoons, A. Corona, Tommaso Felicetti +15 more
2022ACS Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
Mutations in the 3'-PPT Lead to HIV-1 Replication without Integration
C. Richetta, F. Subra, I. Malet, H. Leh +10 more
2022Journal of Virology25 citations Open access
Semantic Scholar
Contribution of Human Retroviruses to Disease Development—A Focus on the HIV– and HERV–Cancer Relationships and Treatment Strategies
Ching-Hsuan Liu, Nicole Grandi, Lalitha Palanivelu, E. Tramontano +1 more
2020Viruses25 citations Open access
Semantic Scholar
Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication.
A. Corona, V. N. Madia, Riccardo De Santis, C. Manelfi +13 more
2023Antiviral Research24 citations Open access
Semantic Scholar
Human Endogenous Retrovirus (HERV) Transcriptome Is Dynamically Modulated during SARS-CoV-2 Infection and Allows Discrimination of COVID-19 Clinical Stages
Nicole Grandi, Maria Chiara Erbì, Sante Scognamiglio, E. Tramontano
2023Microbiology spectrum24 citations Open access
Semantic Scholar
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase.
A. Messore, A. Corona, V. N. Madia, Francesco Saccoliti +16 more
2020ACS Medicinal Chemistry Letters23 citations Open access
Semantic Scholar
Nirmatrelvir treatment of SARS‐CoV‐2‐infected mice blunts antiviral adaptive immune responses
Valeria Fumagalli, P. Di Lucia, M. Ravà, D. Marotta +17 more
2023EMBO Molecular Medicine22 citations Open access
Semantic Scholar
HERV-K(HML7) Integrations in the Human Genome: Comprehensive Characterization and Comparative Analysis in Non-Human Primates
Nicole Grandi, Maria Paola Pisano, Eleonora Pessiu, Sante Scognamiglio +1 more
2021Biology22 citations Open access
Semantic Scholar
1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity
J. Desantis, S. Massari, A. Corona, Andrea Astolfi +7 more
2020Molecules22 citations Open access
Semantic Scholar
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination
Irina Stefanelli, A. Corona, Carmen Cerchia, Emilia Cassese +13 more
2023European journal of medicinal chemistry21 citations Open access
Semantic Scholar
A human MMTV-like betaretrovirus linked to breast cancer has been present in humans at least since the copper age
F. Lessi, Nicole Grandi, C. Mazzanti, Prospero Civita +9 more
2020Aging21 citations Open access
Semantic Scholar
Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production.
A. Corona, Elisa Fanunza, C. Salata, M. J. Morwitzer +11 more
2022Antiviral Research20 citations
Semantic Scholar
Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition.
Simon Hayek, Nicolas Pietrancosta, A. Hovhannisyan, Rodolphe Alves de Sousa +12 more
2019European journal of medicinal chemistry19 citations Open access
Semantic Scholar
Enhanced antitumoral activity of TLR7 agonists via activation of human endogenous retroviruses by HDAC inhibitors
D. Díaz-Carballo, Sahitya Saka, Ali H. Acikelli, Ekaterina Homp +19 more
2021Communications Biology18 citations Open access
Semantic Scholar
Targeting HIV-1 RNase H: N’-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants
A. Corona, E. Ballana, S. Distinto, D. Rogolino +9 more
2020Viruses18 citations Open access
Semantic Scholar
Identification and characterization of ERV-W-like sequences in Platyrrhini species provides new insights into the evolutionary history of ERV-W in primates
Nicole Grandi, Maria Paola Pisano, Martina Demurtas, J. Blomberg +3 more
2020Mobile DNA18 citations Open access
Semantic Scholar
High-Throughput Sequencing is a Crucial Tool to Investigate the Contribution of Human Endogenous Retroviruses (HERVs) to Human Biology and Development
Maria Paola Pisano, Nicole Grandi, E. Tramontano
2020Viruses17 citations Open access
Semantic Scholar
Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach
I. Romeo, F. Ambrosio, G. Costa, A. Corona +10 more
2022Molecules16 citations Open access
Semantic Scholar
Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci
Nicole Grandi, Maria Paola Pisano, Sante Scognamiglio, Eleonora Pessiu +1 more
2020Viruses16 citations Open access
Semantic Scholar
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex
M. Kuzikov, Jeanette Reinshagen, Krzysztof Wycisk, A. Corona +10 more
2024Virus Research15 citations Open access
Semantic Scholar
New Thiazolidine-4-One Derivatives as SARS-CoV-2 Main Protease Inhibitors
A. Messore, Paolo Malune, E. Patacchini, V. N. Madia +19 more
2024Pharmaceuticals15 citations Open access
Semantic Scholar
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach
F. Ambrosio, G. Costa, I. Romeo, F. Esposito +9 more
2023Journal of Chemical Information and Modeling15 citations Open access
Semantic Scholar
The emerging field of human endogenous retroviruses: understanding their physiological role and contribution to diseases
Nicole Grandi, Maria Paola Pisano, E. Tramontano
2019Future Virology15 citations Open access
Semantic Scholar
Garcinol from Garcinia indica inhibits HIV‐1 reverse transcriptase‐associated ribonuclease H
A. Corona, Sebastian Seibt, David Schaller, R. Schobert +3 more
2021Archiv der Pharmazie13 citations Open access
Semantic Scholar
Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function
Irene Boniardi, A. Corona, Jérôme Basquin, C. Basquin +4 more
2023Virus Research12 citations Open access
Semantic Scholar
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route
Sveva Pelliccia, Carmen Cerchia, F. Esposito, Rolando Cannalire +9 more
2022European journal of medicinal chemistry12 citations Open access
Semantic Scholar
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication
A. Corona, V. Onnis, C. Del Vecchio, F. Esposito +2 more
2020Molecules12 citations Open access
Semantic Scholar
Identification of new benzofuran derivatives as STING agonists with broad-spectrum antiviral activity
A. Paulis, A. Onali, P. Vidalain, V. Lotteau +5 more
2024Virus Research11 citations Open access
Semantic Scholar
RNA-Seq Transcriptome Analysis Reveals Long Terminal Repeat Retrotransposon Modulation in Human Peripheral Blood Mononuclear Cells after In Vivo Lipopolysaccharide Injection
Maria Paola Pisano, Olivier Tabone, Maxime Bodinier, Nicole Grandi +3 more
2020Journal of Virology11 citations Open access
Semantic Scholar
Design, and synthesis of 2,4-thiazolidinedione substituted 1,3,5-triazine derivatives as anti-HIV agent via inhibition of reverse transcriptase along with anti-SARS CoV-2, antibacterial and antibiofilm activity.
Saumya Singh, Kumar Saurabh Srivastava, P. Gahtori, A. Anand +7 more
2025Bioorganic chemistry (Print)10 citations Open access
Semantic Scholar
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action
Daniela Iaconis, F. Caccuri, C. Manelfi, C. Talarico +14 more
2023Viruses10 citations Open access
Semantic Scholar
Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome
Sante Scognamiglio, Nicole Grandi, Eleonora Pessiu, E. Tramontano
2022Virus Research10 citations Open access
Semantic Scholar
Unlocking STING as a Therapeutic Antiviral Strategy
A. Paulis, E. Tramontano
2023International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Peptides Mimicking the β7/β8 Loop of HIV-1 Reverse Transcriptase p51 as "Hotspot-Targeted" Dimerization Inhibitors.
P. A. Sánchez-Murcia, S. de Castro, Carlos García-Aparicio, M. Jiménez +7 more
2020ACS Medicinal Chemistry Letters9 citations Open access
Semantic Scholar
Deuteration Strategy-Inspired Design of Novel Diarylpyrimidine Derivatives as Potent Non-Nucleoside Reverse Transcriptase Inhibitors Featuring Improved Efficacy, Selectivity, and Druggability.
Kun Zhang, Tian-Hao Xing, Li Ding, C. Pannecouque +6 more
2025Journal of Medicinal Chemistry8 citations Open access
Semantic Scholar
Structure-Based Design of Novel Thiazolone[3,2-a]pyrimidine Derivatives as Potent RNase H Inhibitors for HIV Therapy
Xuanli Zhu, A. Corona, Stefania Maloccu, E. Tramontano +5 more
2024Molecules8 citations Open access
Semantic Scholar
Prolonged activity of HERV-K(HML2) in Old World Monkeys accounts for recent integrations and novel recombinant variants
Saili Chabukswar, Nicole Grandi, E. Tramontano
2022Frontiers in Microbiology8 citations Open access
Semantic Scholar
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase
A. Messore, A. Corona, V. N. Madia, Francesco Saccoliti +15 more
2021Journal of Medicinal Chemistry8 citations Open access
Semantic Scholar
The Methanolic Extract of Perilla frutescens Robustly Restricts Ebola Virus Glycoprotein-Mediated Entry
Yu-Ting Kuo, Ching-Hsuan Liu, A. Corona, Elisa Fanunza +2 more
2021Viruses8 citations Open access
Semantic Scholar
Human Endogenous Retroviruses (HERVs) and Mammalian Apparent LTRs Retrotransposons (MaLRs) Are Dynamically Modulated in Different Stages of Immunity
Maria Paola Pisano, Nicole Grandi, E. Tramontano
2021Biology8 citations Open access
Semantic Scholar
Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions
R. Meleddu, A. Corona, S. Distinto, F. Cottiglia +12 more
2021Molecules8 citations Open access
Semantic Scholar

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