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J. Kerwin · SciRah

Researcher profile · Semantic Scholar

J. Kerwin

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J. Kerwin — researcher profile on SciRah

h-index: 25
Works: 86
Citations: 2,693

Most-cited papers

Nitric oxide: a new paradigm for second messengers.
J. Kerwin, Jack R. Lancaster, P. Feldman
1995Journal of Medicinal Chemistry510 citations
Semantic Scholar
Nω-nitro-L-arginine: a potent inhibitor of endothelium-derived relaxing factor formation
K. Ishii, B. Chang, J. Kerwin, Zei-Jing Huang +1 more
1990313 citations
Semantic Scholar
The arginine‐nitric oxide pathway: A target for new drugs
J. Kerwin, Michaela Heller
1994Medicinal research reviews (Print)195 citations
Semantic Scholar
Lewis acid catalyzed cyclocondensations of functionalized dienes with aldehydes
S. Danishefsky, J. Kerwin, Susumu Kobayashi
1982151 citations
Semantic Scholar
Synthesis of .beta.-lactams from substituted hydroxamic acids
Marvin J. Miller, P. G. Mattingly, M. A. Morrison, J. Kerwin
1980125 citations
Semantic Scholar
Combinatorial chemistry and molecular diversity in drug discovery
E. Gordon, J. Kerwin
1998124 citations
Semantic Scholar
On the lewis acid catalyzed cyclocondensation of imines with a siloxydiene
J. Kerwin, S. Danishefsky
198388 citations
Semantic Scholar
On the addition of allyltrimethylsilane to glycal acetates
S. Danishefsky, J. Kerwin
198287 citations
Semantic Scholar
Cram rule selectivity in the Lewis acid catalyzed cyclocondensation of chiral aldehydes. A convenient route to chiral systems of biological interest
S. Danishefsky, Susumu Kobayashi, J. Kerwin
198274 citations
Semantic Scholar
Stereochemical consequences of the Lewis acid catalyzed cyclocondensation of oxygenated dienes with aldehydes. A rapid and stereoselective entry to various natural products derived from propionate
S. Danishefsky, N. Kato, D. Askin, J. Kerwin
198262 citations
Semantic Scholar
Claisen rearrangements of lactonic (silyl) enolates: a new route to functionalized cycloalkenes
S. Danishefsky, R. L. Funk, J. Kerwin
198062 citations
Semantic Scholar
Evidence that type A CCK receptors facilitate dopamine efflux in rat brain.
Thomas W. Vickroy, Bruce R. Bianchi, J. Kerwin, H. Kopecká +1 more
1988European Journal of Pharmacology47 citations
Semantic Scholar
Preclinical pharmacology of fiduxosin, a novel alpha(1)-adrenoceptor antagonist with uroselective properties.
A. Hancock, S. Buckner, M. Brune, T. Esbenshade +6 more
2002Journal of Pharmacology and Experimental Therapeutics44 citations Open access
Semantic Scholar
Pharmacological properties of benzazoles. I. Relationship between structure and paralyzing action.
E. F. Domino, K. Unna, J. Kerwin
1952Journal of Pharmacology and Experimental Therapeutics43 citations
Semantic Scholar
Studies in the quinoline series; the preparation of some dialkylaminomethyl-4-quinoline methanols.
K. Campbell, J. Kerwin, R. A. Laforge, B. Campbell
1946Journal of the American Chemical Society41 citations
Semantic Scholar
Biofilm-specific extracellular matrix proteins of non-typeable Haemophilus influenzae
Siva Wu, M. Baum, J. Kerwin, Debbie Guerrero +4 more
2014Pathogens and Disease40 citations Open access
Semantic Scholar
A facile synthesis of substituted N-hydroxy-2-azetidinones. A biogenetic type .beta.-lactam synthesis
P. G. Mattingly, J. Kerwin, Marvin J. Miller
197937 citations
Semantic Scholar
Synthesis of Novel Carbocyclic Adenosine Analogues as Inhibitors of Adenosine Kinase
M. Cowart, M. J. Bennett, J. Kerwin
199934 citations
Semantic Scholar
N omega-nitro-L-arginine: a potent inhibitor of endothelium-derived relaxing factor formation.
K. Ishii, B. Chang, J. Kerwin, Z.-J. Huang +1 more
1990European Journal of Pharmacology34 citations
Semantic Scholar
Hybrid cholecystokinin (CCK) antagonists: new implications in the design and modification of CCK antagonists.
J. Kerwin, Alex M. Nadzan, H. Kopecká, C. W. Lin +3 more
1989Journal of Medicinal Chemistry31 citations Open access
Semantic Scholar
Structure-activity studies for a novel series of bicyclic substituted hexahydrobenz[e]isoindole α1A adrenoceptor antagonists as potential agents for the symptomatic treatment of benign prostatic hyperplasia
M. Meyer, R. Altenbach, H. Bai, F. Basha +12 more
200030 citations Open access
Semantic Scholar
On the Lewis acid catalyzed cyclocondensation of silyloxydienes with .alpha.,.beta.-unsaturated aldehydes
S. Danishefsky, J. Kerwin
198229 citations
Semantic Scholar
Rearrangement of 1,2-Aminochloroalkanes
J. Kerwin, G. Ullyot, R. Fuson, C. L. Zirkle
194729 citations
Semantic Scholar
The anti-androgenic activity of 17α-methyl-B-nortestosterone (SK&F 7690)
H. L. Saunders, K. G. Holden, J. Kerwin
196428 citations
Semantic Scholar
A SIMPLE SYNTHESIS OF DL-CHALCOSE
S. Danishefsky, J. Kerwin
198225 citations
Semantic Scholar
Nitroaromatic amino acids as inhibitors of neuronal nitric oxide synthase.
M. Cowart, E. Kowaluk, J. Daanen, K. Kohlhaas +3 more
1998Journal of Medicinal Chemistry23 citations Open access
Semantic Scholar
Modeling of relationships between pharmacokinetics and blockade of agonist-induced elevation of intraurethral pressure and mean arterial pressure in conscious dogs treated with alpha(1)-adrenoceptor antagonists.
D. Witte, M. Brune, S. Katwala, I. Milicic +6 more
2002Journal of Pharmacology and Experimental Therapeutics20 citations
Semantic Scholar
Actions of A-131701, a novel, selective antagonist for alpha-1A compared with alpha-1B adrenoceptors on intraurethral and blood pressure responses in conscious dogs and a pharmacodynamic assessment of in vivo prostatic selectivity.
A. Hancock, M. Brune, D. G. Witte, K. Marsh +6 more
1998Journal of Pharmacology and Experimental Therapeutics20 citations
Semantic Scholar
Nω-nitro-L-arginine : a potent inhibitor of the L-arginine-dependent soluble guanylate cyclase activation pathway in LLC-PK1 cells
K. Ishii, J. Kerwin, F. Murad
199020 citations
Semantic Scholar
Several relative biological activities of D and L triiodothyronine.
C. Greenberg, Carol A. Bocher, J. Kerwin, S. M. Greenberg +1 more
1961American Journal of Physiology19 citations
Semantic Scholar
Chapter 20. Cholecystokinin Agonists and Antagonists
A. Nadzan, J. Kerwin
199118 citations
Semantic Scholar
Centrally administered CCK-8 suppresses activity in mice by a "peripheral-type" CCK receptor.
D. R. Britton, L. Yahiro, M. J. Cullen, J. Kerwin +2 more
1989Pharmacology, Biochemistry and Behavior18 citations
Semantic Scholar
The Synthesis of C-18 Functionalized Steroid Hormone Analogs. II. Preparation and Some Reactions of 18-Chloro Steroids1a
J. Kerwin, M. Wolff, F. F. Owings, B. Lewis +4 more
196218 citations
Semantic Scholar
THE SYNTHESIS OF C-18 FUNCTIONALIZED STEROID HORMONE ANALOGS. I. A PARTIAL SYNTHESIS OF ALDOSTERONE
M. Wolff, J. Kerwin, F. F. Owings, B. Lewis +3 more
196018 citations
Semantic Scholar
Methodology for the preparation of N-guanidino-modified arginines and related derivatives
F. Wagenaar, J. Kerwin
199316 citations
Semantic Scholar
Cholecystokinin antagonists: (R)-tryptophan-based hybrid antagonists of high affinity and selectivity for CCK-A receptors.
J. Kerwin, F. Wagenaar, H. Kopecká, C. W. Lin +4 more
1991Journal of Medicinal Chemistry15 citations Open access
Semantic Scholar
Effect of Fiduxosin, an Antagonist Selective for α1A- and α1D-Adrenoceptors, on Intraurethral and Arterial Pressure Responses in Conscious Dogs
M. Brune, S. Katwala, I. Milicic, D. Witte +4 more
200213 citations
Semantic Scholar
[3H]R-Terazosin binds selectively to α1-adrenoceptors over α2-adrenoceptors – comparison with racemic [3H]terazosin and [3H]prazosin
L. Ireland, J. C. Cain, G. Rotert, Samuel B. Thomas +3 more
199713 citations
Semantic Scholar
THYROMIMETICS. I. THE SYNTHESIS AND HYPOCHOLESTEREMIC ACTIVITY OF SOME 3' AND 3',5'-ALKYL AND ARYL-3,5-DIIODOTHYRONINES.
B. Blank, F. R. Pfeiffer, C. Greenberg, J. Kerwin
1963Journal of Medicinal Chemistry13 citations
Semantic Scholar
The Synthesis of C-18 Functionalized Hormone Analogs. III. Synthesis of Aldosterone1a
M. Wolff, J. Kerwin, F. F. Owings, B. Lewis +1 more
196312 citations
Semantic Scholar
Adrenergic Blocking Agents. III. N-(Aryloxyisopropyl)-β-haloethylamines1
J. Kerwin, G. C. Hall, F. Milnes, I. H. Witt +4 more
195112 citations
Semantic Scholar
PROTOLYTIC AND PYROLYTIC REARRANGEMENTS OF POLYCYCLIC METHYL CYCLOPROPYL KETONES
X. Creary, Frances Hudock, M. Keller, J. Kerwin +1 more
197710 citations
Semantic Scholar
The Synthesis of Some Potential Hypoglycemic Agents1
B. Blank, F. A. Farina, J. Kerwin, H. L. Saunders
196110 citations
Semantic Scholar
THYROMIMETICS. II. THE SYNTHESIS AND HYPOCHOLESTEREMIC ACTIVITY OF SOME BETA-DIETHYLAMINOETHYL ESTERS OF IODINATED THYROALKANOIC ACIDS.
B. Blank, F. R. Pfeiffer, C. Greenberg, J. Kerwin
1963Journal of Medicinal Chemistry9 citations
Semantic Scholar
Studies in the quinoline series; the preparation of some alpha-dialkylamino-methyl-8-quinoline methanols.
K. Campbell, J. Kerwin
1946Journal of the American Chemical Society9 citations
Semantic Scholar
Effect of fiduxosin, an antagonist selective for alpha(1A)- and alpha(1D)-adrenoceptors, on intraurethral and arterial pressure responses in conscious dogs.
M. Brune, S. Katwala, I. Milicic, D. Witte +4 more
2002Journal of Pharmacology and Experimental Therapeutics8 citations
Semantic Scholar
Synthesis of phosphorus-containing amino acid analogs as inhibitors of nitric oxide synthase
M. Cowart, E. Kowaluk, K. Kohlhaas, Karen M. Alexander +1 more
19968 citations
Semantic Scholar
Reaction of Epoxides with 2-Aminobenzenethiol
J. Kerwin, J. E. Mccarty, C. A. Vanderwerf
19598 citations
Semantic Scholar
A New Carbocyclic Steroid Structure: 12,18-Cyclosteroids
Vlasios Georgian, J. Kerwin, M. Wolff, F. F. Owings
19627 citations
Semantic Scholar
Adrenergic Blocking Agents. I. N-(9-Fluorenyl)-β-chloroethylamine Series1
J. Kerwin, T. Herdegen, Robert Y. Heisler, G. Ullyot
19507 citations
Semantic Scholar

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S. Danishefsky×8
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M. Meyer — researcher profile on SciRah

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D. Witte — researcher profile on SciRah

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H. Kopecká — researcher profile on SciRah

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I. Milicic — researcher profile on SciRah

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M. Wolff — researcher profile on SciRah

F. F. Owings×4

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K. Ishii — researcher profile on SciRah