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J. Parsons · SciRah

Researcher profile · Semantic Scholar

J. Parsons

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J. Parsons — researcher profile on SciRah

h-index: 68
Works: 177
Citations: 28K

Most-cited papers

Cell Migration: Integrating Signals from Front to Back
A. Ridley, M. Schwartz, K. Burridge, R. Firtel +4 more
2003Science5,262 citations Open access
Semantic Scholar
FAK–Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly
D. Webb, K. Donais, Leanna A. Whitmore, Sheila M. Thomas +3 more
2004Nature Cell Biology1,453 citations
Semantic Scholar
Focal adhesion kinase: the first ten years
J. Parsons
2003Journal of Cell Science1,403 citations Open access
Semantic Scholar
Src family kinases, key regulators of signal transduction
S. Parsons, J. Parsons
2004Oncogene971 citations Open access
Semantic Scholar
HDAC6 modulates cell motility by altering the acetylation level of cortactin.
X. Zhang, Zhigang Yuan, Yingtao Zhang, S. Yong +9 more
2007Molecules and Cells730 citations Open access
Semantic Scholar
Focal Adhesion Kinase: a regulator of focal adhesion dynamics and cell movement
J. Parsons, Karen H. Martin, J. K. Slack, Joan M. Taylor +1 more
2000Oncogene696 citations Open access
Semantic Scholar
Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation.
Alissa M. Weaver, Andrei V. Karginov, Andrew W. Kinley, Scott A. Weed +3 more
2001Current Biology627 citations Open access
Semantic Scholar
Cortactin Localization to Sites of Actin Assembly in Lamellipodia Requires Interactions with F-Actin and the Arp2/3 Complex
Scott A. Weed, Andrei V. Karginov, Dorothy A. Schafer, Alissa M. Weaver +3 more
2000Journal of Cell Biology430 citations Open access
Semantic Scholar
Cortactin: coupling membrane dynamics to cortical actin assembly
Scott A. Weed, J. Parsons
2001Oncogene418 citations Open access
Semantic Scholar
Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways.
J. Parsons, S. Parsons
1997Current Opinion in Cell Biology408 citations
Semantic Scholar
Cell Migration--Movin' On
A. R. Horwitz, J. Parsons
1999Science398 citations
Semantic Scholar
p130Cas, a Substrate Associated with v-Src and v-Crk, Localizes to Focal Adhesions and Binds to Focal Adhesion Kinase*
Mary T. Harte, Jeffrey D. Hildebrand, M. Burnham, A. Bouton +1 more
1996Journal of Biological Chemistry369 citations Open access
Semantic Scholar
Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation
Alan Richardson, R. Malik, Jeffrey D. Hildebrand, J. Parsons
1997Molecular and Cellular Biology341 citations Open access
Semantic Scholar
Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype
Robert W. Tilghman, C. Cowan, J. Mih, Yulia Koryakina +5 more
2010PLoS ONE337 citations Open access
Semantic Scholar
Interaction of cortactin and N-WASp with Arp2/3 complex.
Alissa M. Weaver, John E. Heuser, Andrei V. Karginov, Wei-Lih Lee +2 more
2002Current Biology271 citations Open access
Semantic Scholar
Identification of a Novel Cortactin SH3 Domain-Binding Protein and Its Localization to Growth Cones of Cultured Neurons
Yunrui Du, Scott A. Weed, Wen Xiong, T. Marshall +1 more
1998Molecular and Cellular Biology268 citations Open access
Semantic Scholar
Integrin connections map: to infinity and beyond.
Karen H. Martin, J. K. Slack, S. Boerner, C. Martin +1 more
2002Science245 citations
Semantic Scholar
Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells
J. K. Slack, R. Adams, Joshua D. Rovin, Eric A. Bissonette +2 more
2001Oncogene215 citations
Semantic Scholar
Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment
J. B. Stokes, Sara J. Adair, Jill K. Slack-Davis, D. Walters +9 more
2011Molecular Cancer Therapeutics211 citations Open access
Semantic Scholar
Translocation of cortactin to the cell periphery is mediated by the small GTPase Rac1.
Scott A. Weed, Yunrui Du, J. Parsons
1998Journal of Cell Science202 citations
Semantic Scholar
Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion.
Andrew W. Kinley, Scott A. Weed, Alissa M. Weaver, Andrei V. Karginov +3 more
2003Current Biology185 citations Open access
Semantic Scholar
Cortactin tyrosine phosphorylation requires Rac1 activity and association with the cortical actin cytoskeleton.
Julie A. Head, Dong-Yang Jiang, Min Li, Lynda J. Zorn +3 more
2003Molecular Biology of the Cell182 citations Open access
Semantic Scholar
Focal adhesion kinase as a regulator of cell tension in the progression of cancer.
Robert W. Tilghman, J. Parsons
2008Seminars in Cancer Biology178 citations Open access
Semantic Scholar
Selective Expression of an Endogenous Inhibitor of FAK Regulates Proliferation and Migration of Vascular Smooth Muscle Cells
Joan M. Taylor, Christopher P. Mack, K. Nolan, Christopher P. Regan +2 more
2001Molecular and Cellular Biology177 citations Open access
Semantic Scholar
Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells
R. Tilghman, Jill K. Slack-Davis, N. Sergina, Karen H. Martin +5 more
2005Journal of Cell Science164 citations Open access
Semantic Scholar
A Role for Focal Adhesion Kinase in Phenylephrine-induced Hypertrophy of Rat Ventricular Cardiomyocytes*
Joan M. Taylor, Joshua D. Rovin, J. Parsons
2000Journal of Biological Chemistry146 citations Open access
Semantic Scholar
FAK phosphorylation sites mapped by mass spectrometry
P. Grigera, Erin D. Jeffery, Karen H. Martin, J. Shabanowitz +2 more
2005Journal of Cell Science139 citations Open access
Semantic Scholar
Focal Adhesion Kinase: Targeting Adhesion Signaling Pathways for Therapeutic Intervention
J. Parsons, Jill K. Slack-Davis, R. Tilghman, W. Roberts
2008Clinical Cancer Research122 citations
Semantic Scholar
FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts
Marcin P. Iwanicki, T. Vomastek, R. Tilghman, Karen H. Martin +3 more
2008Journal of Cell Science116 citations Open access
Semantic Scholar
Regulated Expression of Focal Adhesion Kinase-Related Nonkinase, the Autonomously Expressed C-Terminal Domain of Focal Adhesion Kinase
K. Nolan, J. Lacoste, J. Parsons
1999Molecular and Cellular Biology114 citations Open access
Semantic Scholar
Expression and characterization of splice variants of PYK2, a focal adhesion kinase-related protein.
Wen-Cheng Xiong, M. Macklem, J. Parsons
1998Journal of Cell Science113 citations
Semantic Scholar
Involvement of the Src-cortactin pathway in podosome formation and turnover during polarization of cultured osteoclasts
Chen Luxenburg, J. Parsons, L. Addadi, B. Geiger
2006Journal of Cell Science112 citations Open access
Semantic Scholar
Cytoskeletal changes induced by GRAF, the GTPase regulator associated with focal adhesion kinase, are mediated by Rho.
Joan M. Taylor, M. Macklem, J. Parsons
1999Journal of Cell Science112 citations
Semantic Scholar
The identification of p130cas-binding proteins and their role in cellular transformation.
M. Burnham, Mary T. Harte, Alan Richardson, J. Parsons +1 more
1996Oncogene101 citations
Semantic Scholar
Serine phosphorylation of focal adhesion kinase in interphase and mitosis: a possible role in modulating binding to p130(Cas).
Amy Ma, Alan Richardson, E. Schaefer, J. Parsons
2001Molecular Biology of the Cell96 citations Open access
Semantic Scholar
Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape.
P. Hou, Lourdes Estrada, Andrew W. Kinley, J. Parsons +2 more
2003Human Molecular Genetics94 citations
Semantic Scholar
RACK1 Targets the Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase Pathway To Link Integrin Engagement with Focal Adhesion Disassembly and Cell Motility
T. Vomastek, Marcin P. Iwanicki, H. Schaeffer, A. Tarcsafalvi +2 more
2007Molecular and Cellular Biology93 citations Open access
Semantic Scholar
Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells
L. Bougnères, S. Girardin, Scott A. Weed, Andrei V. Karginov +4 more
2004Journal of Cell Biology93 citations Open access
Semantic Scholar
Expression of focal adhesion kinase in normal and pathologic human prostate tissues
Joshua D. Rovin, H. Frierson, W. Ledinh, J. Parsons +1 more
2002The Prostate83 citations
Semantic Scholar
Focal adhesion kinase modulates activation of NF-kappaB by flow in endothelial cells.
T. Petzold, A. Orr, Cornelia S. Hahn, K. A. Jhaveri +2 more
2009American Journal of Physiology - Cell Physiology82 citations Open access
Semantic Scholar
Inhibition of the growth of patient-derived pancreatic cancer xenografts with the MEK inhibitor trametinib is augmented by combined treatment with the epidermal growth factor receptor/HER2 inhibitor lapatinib.
D. Walters, James M. Lindberg, Sara J. Adair, T. Newhook +9 more
2013Neoplasia80 citations Open access
Semantic Scholar
Characterization of Graf, the GTPase-activating Protein for Rho Associated with Focal Adhesion Kinase
Joan M. Taylor, Jeffrey D. Hildebrand, C. P. Mack, M. Cox +1 more
1998Journal of Biological Chemistry80 citations Open access
Semantic Scholar
CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer
A. Michaels, T. Newhook, Sara J. Adair, S. Morioka +9 more
2017Clinical Cancer Research79 citations Open access
Semantic Scholar
Integrin-dependent Activation of the p70 Ribosomal S6 Kinase Signaling Pathway*
R. Malik, J. Parsons
1996Journal of Biological Chemistry77 citations Open access
Semantic Scholar
Mislocalization or Reduced Expression of Arf GTPase-activating Protein ASAP1 Inhibits Cell Spreading and Migration by Influencing Arf1 GTPase Cycling*
Yun-Hao Liu, Gil M. Yerushalmi, P. Grigera, J. Parsons
2005Journal of Biological Chemistry74 citations Open access
Semantic Scholar
Extracellular Signal-Regulated Kinase 2 (ERK2) Phosphorylation Sites and Docking Domain on the Nuclear Pore Complex Protein Tpr Cooperatively Regulate ERK2-Tpr Interaction
T. Vomastek, Marcin P. Iwanicki, W. R. Burack, Divya Tiwari +4 more
2008Molecular and Cellular Biology65 citations Open access
Semantic Scholar
Cas and NEDD9 Contribute to Tumor Progression through Dynamic Regulation of the Cytoskeleton.
Michael S. Guerrero, J. Parsons, A. Bouton
2012Genes & cancer50 citations Open access
Semantic Scholar
Differential Requirement for Focal Adhesion Kinase Signaling in Cancer Progression in the Transgenic Adenocarcinoma of Mouse Prostate Model
Jill K. Slack-Davis, E. Hershey, D. Theodorescu, H. Frierson +1 more
2009Molecular Cancer Therapeutics49 citations Open access
Semantic Scholar
c-Src tyrosine phosphorylation of epidermal growth factor receptor, P190 RhoGAP, and focal adhesion kinase regulates diverse cellular processes.
Michelle D. Haskell, J. K. Slack, J. Parsons, S. Parsons
2001Chemical Reviews49 citations
Semantic Scholar
Cortactin phosphorylation sites mapped by mass spectrometry
Karen H. Martin, Erin D. Jeffery, P. Grigera, J. Shabanowitz +2 more
2006Journal of Cell Science43 citations Open access
Semantic Scholar

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Scott A. Weed×9
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Scott A. Weed — researcher profile on SciRah
Karen H. Martin×6
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Karen H. Martin — researcher profile on SciRah
Andrei V. Karginov×5
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Andrei V. Karginov — researcher profile on SciRah
J. K. Slack×4
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J. K. Slack — researcher profile on SciRah

Alissa M. Weaver

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Alissa M. Weaver — researcher profile on SciRah

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A. Bouton — researcher profile on SciRah

Jill K. Slack-Davis×4

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Jill K. Slack-Davis — researcher profile on SciRah

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R. Tilghman — researcher profile on SciRah

Marcin P. Iwanicki×4

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Marcin P. Iwanicki — researcher profile on SciRah

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S. Parsons — researcher profile on SciRah

Andrew W. Kinley×3

John A. Cooper×3

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John A. Cooper — researcher profile on SciRah