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F. Loechel · SciRah

Researcher profile · Semantic Scholar

F. Loechel

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F. Loechel — researcher profile on SciRah

h-index: 25
Works: 39
Citations: 3,358

Most-cited papers

A Novel, Secreted Form of Human ADAM 12 (Meltrin α) Provokes Myogenesis in Vivo *
Brent J. Gilpin, F. Loechel, M. Mattéi, E. Engvall +2 more
1998Journal of Biological Chemistry345 citations Open access
Semantic Scholar
ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3.
F. Loechel, J. Fox, Gillian Murphy, R. Albrechtsen +1 more
2000Biochemical and Biophysical Research Communications - BBRC333 citations
Semantic Scholar
The Cysteine-Rich Domain of Human Adam 12 Supports Cell Adhesion through Syndecans and Triggers Signaling Events That Lead to β1 Integrin–Dependent Cell Spreading
K. Iba, R. Albrechtsen, Brent J. Gilpin, Camilla Fröhlich +10 more
2000Journal of Cell Biology272 citations Open access
Semantic Scholar
Cysteine-rich domain of human ADAM 12 (meltrin alpha) supports tumor cell adhesion.
K. Iba, R. Albrechtsen, Brent J. Gilpin, F. Loechel +1 more
1999American Journal of Pathology221 citations Open access
Semantic Scholar
Merosin and laminin in myogenesis; specific requirement for merosin in myotube stability and survival
P. Vachon, F. Loechel, Hong Xu, U. Wewer +1 more
1996Journal of Cell Biology217 citations Open access
Semantic Scholar
ADAM 12, a Disintegrin Metalloprotease, Interacts with Insulin-like Growth Factor-binding Protein-3*
Zengdun Shi, Wen-Zhong Xu, F. Loechel, U. Wewer +1 more
2000Journal of Biological Chemistry194 citations Open access
Semantic Scholar
Merosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models.
W. Kuang, Hong Xu, P. Vachon, Ling A. Liu +3 more
1998Journal of Clinical Investigation194 citations Open access
Semantic Scholar
Integrins (alpha7beta1) in muscle function and survival. Disrupted expression in merosin-deficient congenital muscular dystrophy.
P. Vachon, Hong Xu, Ling A. Liu, F. Loechel +5 more
1997Journal of Clinical Investigation190 citations Open access
Semantic Scholar
Human ADAM 12 (Meltrin α) Is an Active Metalloprotease*
F. Loechel, Brent J. Gilpin, E. Engvall, R. Albrechtsen +1 more
1998Journal of Biological Chemistry159 citations Open access
Semantic Scholar
Immune response to a carcinoembryonic antigen polynucleotide vaccine.
R. Conry, A. Lobuglio, J. Kantor, J. Schlom +6 more
1994Cancer Research142 citations
Semantic Scholar
Regulation of Human ADAM 12 Protease by the Prodomain
F. Loechel, M. Overgaard, C. Oxvig, R. Albrechtsen +1 more
1999Journal of Biological Chemistry133 citations Open access
Semantic Scholar
A carcinoembryonic antigen polynucleotide vaccine has in vivo antitumor activity.
R. Conry, A. Lobuglio, F. Loechel, S. Moore +3 more
1995Gene Therapy128 citations
Semantic Scholar
Intracellular single-chain antibody directed against erbB2 down-regulates cell surface erbB2 and exhibits a selective anti-proliferative effect in erbB2 overexpressing cancer cell lines.
J. Deshane, F. Loechel, R. Conry, G. P. Siegal +2 more
1994Gene Therapy108 citations
Semantic Scholar
ADAM 12 protease induces adipogenesis in transgenic mice.
Nobuko Kawaguchi, Xiufeng Xu, Rie Tajima, P. Kronqvist +4 more
2002American Journal of Pathology105 citations Open access
Semantic Scholar
Tetranectin is a novel marker for myogenesis during embryonic development, muscle regeneration, and muscle cell differentiation in vitro.
U. Wewer, K. Iba, M. Durkin, F. Nielsen +5 more
1998Developmental Biology80 citations Open access
Semantic Scholar
A carcinoembryonic antigen polynucleotide vaccine for human clinical use.
R. Conry, A. Lobuglio, F. Loechel, S. Moore +4 more
1995Cancer Gene Therapy77 citations
Semantic Scholar
Trafficking of human ADAM 12-L: retention in the trans-Golgi network.
S. Hougaard, F. Loechel, Xiufeng Xu, Rie Tajima +2 more
2000Biochemical and Biophysical Research Communications - BBRC72 citations
Semantic Scholar
Tissue‐specific expression of the human laminin α5‐chain, and mapping of the gene to human chromosome 20q13.2‐13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation
Marian E. Durkin, F. Loechel, M. Mattéi, Brent J. Gilpin +2 more
1997FEBS Letters59 citations Open access
Semantic Scholar
Nuclear Export Inhibitors and Kinase Inhibitors Identified Using a MAPK-Activated Protein Kinase 2 Redistribution® Screen
D. L. Almholt, F. Loechel, S. Nielsen, C. Krog-Jensen +10 more
2004Assay and drug development technologies51 citations
Semantic Scholar
Identification of Akt Pathway Inhibitors Using Redistribution Screening on the FLIPR and the IN Cell 3000 Analyzer
B. K. Lundholt, Viggo Linde, F. Loechel, Hans-Christian Pedersen +9 more
2005Journal of biomolecular screening50 citations Open access
Semantic Scholar
Non-anti-coagulant heparins: a promising approach for prevention of tumor metastasis (review).
M. Kragh, F. Loechel
2005International Journal of Oncology40 citations
Semantic Scholar
Extrasynaptic location of laminin beta 2 chain in developing and adult human skeletal muscle.
U. Wewer, L. Thornell, F. Loechel, X. Zhang +6 more
1997American Journal of Pathology39 citations
Semantic Scholar
Structural Organization of the Human and Mouse Laminin β2 Chain Genes, and Alternative Splicing at the 5′ End of the Human Transcript*
M. Durkin, M. Gautam, F. Loechel, J. Sanes +3 more
1996Journal of Biological Chemistry34 citations Open access
Semantic Scholar
The identification of GPR3 inverse agonist AF64394; the first small molecule inhibitor of GPR3 receptor function.
Thomas N. Jensen, L. Elster, S. M. Nielsen, S. Poda +5 more
2014Bioorganic & Medicinal Chemistry Letters33 citations
Semantic Scholar
Immunization with a plasmid expressing pneumococcal surface protein A (PspA) can elicit protection against fatal infection with Streptococcus pneumoniae
L. McDaniel, F. Loechel, C. Benedict, T. Greenway +3 more
1997Gene Therapy27 citations Open access
Semantic Scholar
Identification of RAS-Mitogen-Activated Protein Kinase Signaling Pathway Modulators in an ERF1 Redistribution® Screen
C. Grånäs, B. K. Lundholt, F. Loechel, Hans-Christian Pedersen +6 more
2006Journal of biomolecular screening15 citations Open access
Semantic Scholar
Activation of ADAM 12 protease by copper
F. Loechel, U. Wewer
2001FEBS Letters14 citations
Semantic Scholar
Profiling of multiple signal pathway activities by multiplexing antibody and GFP-based translocation assays.
U. Henriksen, J. Fog, F. Loechel, Morten Praestegaard
2008Combinatorial chemistry & high throughput screening9 citations
Semantic Scholar
High content translocation assays for pathway profiling.
F. Loechel, S. P. Bjørn, Viggo Linde, Morten Praestegaard +1 more
2007Methods in molecular biology9 citations
Semantic Scholar
Regulation of laminin β2 chain gene expression in human cancer cell lines
M. Durkin, F. Nielsen, F. Loechel, R. Albrechtsen +1 more
20013 citations Open access
Semantic Scholar
Regulation of laminin beta2 chain gene expression in human cancer cell lines.
M. Durkin, F. Nielsen, F. Loechel, R. Albrechtsen +1 more
2001European Journal of Biochemistry2 citations
Semantic Scholar
Targeted eradication of ErbB-2 over-expressing tumor cells employing expression of an intracellular antibody directed against the ErbB-2 oncoprotein
J. Deshane, J. Grim, M. Feng, F. Loechel +2 more
19952 citations
Semantic Scholar
Integrins ( alpha 7 beta 1 ) in muscle function and survival . Disrupted expression in merosin-deficient congenital muscular dystrophy
P. Vachon, Hong Xu, Ling A. Liu, F. Loechel +5 more
20181 citations
Semantic Scholar
Extrasynaptic Localization of Laminin (32 Chain in Developing and Adult Human Skeletal Muscle
U. Wewer, L. Thornell, F. Loechel, Xiao-Min Zhang +9 more
20071 citations
Semantic Scholar
Disrupted Expression in Merosin-deficient Congenital Muscular Dystrophy
P. Vachon, Hong Xu, Ling A. Liu, F. Loechel +5 more
19971 citations
Semantic Scholar
Integrins ( a 7 b 1 ) in Muscle Function and Survival Disrupted Expression in Merosin-deficient Congenital Muscular Dystrophy
P. Vachon, Hong Xu, Ling A. Liu, F. Loechel +5 more
20130 citations
Semantic Scholar
Evaluate Compound Toxicity Early in the Drug Discovery Process Using High Content Analysis in Cell-Based Assays
J. Fog, L. Gjelstrup, F. Loechel, M. Præstegaard
20080 citations
Semantic Scholar
Extrasynaptic Localization ofLaminin (32Chainin Developing andAdult HumanSkeletal Muscle
L. Thornell, F. Loechel, Xiao-Min Zhang, S. Amano +1 more
19970 citations
Semantic Scholar
To live or let die
P. Vachon, F. Loechel, Hong Xu, U. Wewer +1 more
19960 citations
Semantic Scholar

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