Researcher profile · Semantic Scholar

N. Leidenheimer

h-index: 18
Works: 36
Citations: 1,610

Most-cited papers

A genetically encoded fluorescent sensor for in vivo imaging of GABA
J. Marvin, Y. Shimoda, Vincent Magloire, Marco Leite +11 more
2018Nature Methods321 citations Open access
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Efficient neuronal gene transfer with AAV8 leads to neurotoxic levels of tau or green fluorescent proteins.
R. Klein, Robert D. Dayton, N. Leidenheimer, K. Jansen +2 more
2006Molecular Therapy211 citations Open access
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Activation of protein kinase C selectively inhibits the gamma-aminobutyric acidA receptor: role of desensitization.
N. Leidenheimer, S. McQuilkin, L. Hahner, P. Whiting +1 more
1992Molecular Pharmacology130 citations
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Activation of Protein Kinase C Induces γ-Aminobutyric Acid Type A Receptor Internalization in Xenopus Oocytes*
R. Chapell, O. Bueno, X. Alvarez-Hernandez, L. C. Robinson +1 more
1998Journal of Biological Chemistry111 citations Open access
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Constitutive GABAA Receptor Endocytosis Is Dynamin-mediated and Dependent on a Dileucine AP2 Adaptin-binding Motif within the β2 Subunit of the Receptor*
Dina Herring, Renqi Huang, Mehar Singh, L. C. Robinson +2 more
2003Journal of Biological Chemistry109 citations Open access
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Pharmacological Chaperoning: A Primer on Mechanism and Pharmacology
N. Leidenheimer, K. Ryder
2014Pharmacological Research99 citations Open access
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Effects of PKC activation and receptor desensitization on neurosteroid modulation of GABA(A) receptors.
N. Leidenheimer, R. Chapell
1997Brain Research. Molecular Brain Research93 citations
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PKC modulation of GABAA receptor endocytosis and function is inhibited by mutation of a dileucine motif within the receptor beta 2 subunit.
Dina Herring, Renqi Huang, Meharvan Singh, G. H. Dillon +1 more
2005Neuropharmacology71 citations
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Discriminative stimulus control by the anxiogenic beta-carboline FG 7142: generalization to a physiological stressor.
N. Leidenheimer, M. D. Schechter
1988Pharmacology, Biochemistry and Behavior70 citations
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GABA Acts as a Ligand Chaperone in the Early Secretory Pathway to Promote Cell Surface Expression of GABAA Receptors
Randa S. Eshaq, Letha D. Stahl, R. Stone, Sheryl S. Smith +2 more
2010Brain Research48 citations Open access
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Phosphorylation-independent effects of second messenger system modulators on gamma-aminobutyric acidA receptor complex function.
N. Leidenheimer, Michael D. Browning, T. Dunwiddie, L. Hahner +1 more
1990Molecular Pharmacology40 citations
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Effect of PKG activation on recombinant GABAA receptors.
N. Leidenheimer
1996Brain Research. Molecular Brain Research31 citations
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Direct channel-gating and modulatory effects of triiodothyronine on recombinant GABA(A) receptors.
R. Chapell, Joseph V. Martin, T. Machu, N. Leidenheimer
1998European Journal of Pharmacology29 citations
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Regulation of excitation by GABA(A) receptor internalization.
N. Leidenheimer
2008Results and problems in cell differentiation28 citations
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Inhibition of the activity of the native γ-aminobutyric acidA receptor by metabolites of thyroid hormones: correlations with molecular modeling studies
Joseph V. Martin, J. Padrón, M. Newman, R. Chapell +2 more
200425 citations
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Colchicine inhibits GABA(A) receptors independently of microtubule depolymerization.
O. Bueno, N. Leidenheimer
1998Neuropharmacology22 citations
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Neuronal gamma-aminobutyric acid (GABA) type A receptors undergo cognate ligand chaperoning in the endoplasmic reticulum by endogenous GABA
Ping Wang, Randa S. Eshaq, C. Meshul, C. Moore +2 more
2015Frontiers in Cellular Neuroscience21 citations Open access
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Mechanisms of homomeric alpha1 glycine receptor endocytosis.
Renqi Huang, Shao-Qing He, Zhenglan Chen, G. H. Dillon +1 more
2007Biochemistry20 citations Open access
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Activation of protein kinase C induces gamma-aminobutyric acid type A receptor internalization in Xenopus oocytes.
R. Chapell, O. Bueno, X. Alvarez-Hernandez, L. C. Robinson +1 more
1998Journal of Biological Chemistry19 citations
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Pharmacological Chaperones: Beyond Conformational Disorders.
N. Leidenheimer
2018Handbook of Experimental Pharmacology17 citations
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A Targeted Bioinformatics Assessment of Adrenocortical Carcinoma Reveals Prognostic Implications of GABA System Gene Expression
Erika Knott, N. Leidenheimer
2020International Journal of Molecular Sciences16 citations Open access
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The role of loop F residues in determining differential d-tubocurarine potencies in mouse and human 5-hydroxytryptamine 3A receptors.
Ran Zhang, Xiaofei Wen, J. Militante, B. Hester +6 more
2007Biochemistry16 citations
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Temperature: an important experimental variable in studying PKC modulation of ligand-gated ion channels.
T. Machu, G. H. Dillon, Renqi Huang, D. Lovinger +1 more
2006Brain Research12 citations
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Cyclic AMP-dependent protein kinase decreases gamma-aminobutyric acidA receptor-mediated 36Cl- uptake by brain microsacs.
N. Leidenheimer, T. Machu, S. Endo, R. Olsen +2 more
1991Journal of Neurochemistry12 citations
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Inverse agonist properties of the FG 7142 discriminative stimulus.
N. Leidenheimer, M. D. Schechter
1991Pharmacology, Biochemistry and Behavior11 citations
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Evidence for noradrenergic involvement in mediating the FG 7142 discriminative stimulus.
N. Leidenheimer, M. D. Schechter
1992Pharmacology, Biochemistry and Behavior8 citations
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Discriminative stimulus properties of CGS 9896: interactions within the GABA/benzodiazepine receptor complex.
N. Leidenheimer, M. D. Schechter
1988Pharmacology, Biochemistry and Behavior7 citations
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Localization and functional expression of alternatively spliced forms of the GABAA receptor γ2 subunit
J. Sikela, N. Leidenheimer, C. Gambarana, K. Buck +4 more
19916 citations
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Cognate Ligand Chaperoning: a Novel Mechanism for the Post-translational Regulation of Neurotransmitter Receptor Biogenesis
N. Leidenheimer
2017Frontiers in Cellular Neuroscience4 citations Open access
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Inverse agonist properties of the THBC discriminative stimulus: asymmetrical generalization with FG 7142.
N. Leidenheimer, M. D. Schechter
1991Pharmacology, Biochemistry and Behavior4 citations
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Abstract 5486: The role of the GABA shunt in prostate cancer metabolic reprogramming and aggressive phenotype
Erika Knott, S. Miriyala, H. Nam, M. Panchatcharam +1 more
2018Molecular and Cellular Biology / Genetics1 citations
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Abstract 2408: Targeted bioinformatics analysis identifies highABATtranscript expression as a multi-cancer marker of favorable patient prognosis
Erika Knott, N. Leidenheimer
2021Molecular and Cellular Biology/Genetics0 citations
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GAMMA AMINOBUTYRIC ACID A RECEPTOR PI SUBUNIT EXPRESSION AS A PROGNOSTIC BIOMARKER FOR COLON CANCER PATIENTS
T. Dobbin, Grace A. Maresh, L. Hellmers, X. Zhang +4 more
20200 citations
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Abstract 4401: GABA system expression level changes persist across cancers of many organ systems
Erika Knott, N. Leidenheimer
2020Clinical research0 citations
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Abstract 4379: Prostate cancer cells utilize the GABA shunt to enhance oxidative metabolism
Erika Knott, S. Miriyala, M. Panchatcharam, N. Leidenheimer
2019Molecular and Cellular Biology / Genetics0 citations
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Localization and functional expression of alternatively spliced forms of the GABA(A) receptor gamma(2) subunit.
J. Sikela, N. Leidenheimer, C. Gambarana, K. Buck +4 more
1991Molecular and cellular neurosciences0 citations
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G. H. Dillon

×4

T. Machu×4

R. Harris×3

R. Chapell×3

L. Hahner×2

O. Bueno×2

X. Alvarez-Hernandez×2

Dina Herring×2