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M. Abdelrahman · SciRah

Researcher profile · Semantic Scholar

M. Abdelrahman

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M. Abdelrahman — researcher profile on SciRah

h-index: 21
Works: 45
Citations: 1,265

Most-cited papers

Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp.
M. Rateb, W. Houssen, Markus F. F. Arnold, M. Abdelrahman +10 more
2011Journal of Natural Products133 citations Open access
Semantic Scholar
Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino[1,2-a]indol-1(2H)-ones as potential anticancer agents effecting the reactive oxygen species production.
B. Youssif, M. Abdelrahman, Ahmed H. Abdelazeem, M. Abdelgawad +5 more
2018European journal of medicinal chemistry75 citations Open access
Semantic Scholar
Design and synthesis of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as antiproliferative EGFR and BRAFV600E dual inhibitors.
L. Al-Wahaibi, A. Gouda, Ola F Abou-Ghadir, O. I. Salem +6 more
2020Bioorganic chemistry (Print)64 citations
Semantic Scholar
In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569
T. Gamage, Bogna Marta Ignatowska-Jankowska, J. Wiley, M. Abdelrahman +8 more
2014Behavioural Pharmacology63 citations Open access
Semantic Scholar
Design, synthesis, and biological evaluation of novel EGFR inhibitors containing 5-chloro-3-hydroxymethyl-indole-2-carboxamide scaffold with apoptotic antiproliferative activity.
F. Mohamed, H. Gomaa, O. Hendawy, Asmaa T. Ali +6 more
2021Bioorganic chemistry (Print)61 citations
Semantic Scholar
5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents.
B. Youssif, A. Mohamed, E. E. A. Osman, Ola F Abou-Ghadir +4 more
2019European journal of medicinal chemistry61 citations
Semantic Scholar
Synthesis, biological evaluation, docking study and ulcerogenicity profiling of some novel quinoline-2-carboxamides as dual COXs/LOX inhibitors endowed with anti-inflammatory activity.
M. Abdelrahman, B. Youssif, M. Abdelgawad, Ahmed H. Abdelazeem +4 more
2017European journal of medicinal chemistry60 citations Open access
Semantic Scholar
Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities.
H. Gomaa, Mohamed E. Shaker, Sami I. Alzarea, O. Hendawy +7 more
2022Bioorganic chemistry (Print)57 citations
Semantic Scholar
Novel pyrrol-2(3H)-ones and pyridazin-3(2H)-ones carrying quinoline scaffold as anti-proliferative tubulin polymerization inhibitors.
Mahmoud S. Abdelbaset, G. Abuo-Rahma, M. Abdelrahman, M. Ramadan +4 more
2018Bioorganic chemistry (Print)57 citations
Semantic Scholar
Synoxazolidinone C; a bicyclic member of the synoxazolidinone family with antibacterial and anticancer activities
Margey Tadesse, J. Svenson, M. Jaspars, M. Strøm +6 more
201153 citations
Semantic Scholar
Discovery of novel thienoquinoline-2-carboxamide chalcone derivatives as antiproliferative EGFR tyrosine kinase inhibitors.
Mahmoud S. Abdelbaset, Mohamed Abdel-Aziz, M. Ramadan, M. Abdelrahman +3 more
2019Bioorganic & Medicinal Chemistry51 citations Open access
Semantic Scholar
Utilization of tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidinone as a cap moiety in design of novel histone deacetylase inhibitors.
M. Mohamed, B. Youssif, M. Shaykoon, M. Abdelrahman +3 more
2019Bioorganic chemistry (Print)49 citations
Semantic Scholar
Design, synthesis, docking studies and biological evaluation of novel chalcone derivatives as potential histone deacetylase inhibitors.
M. Mohamed, M. Shaykoon, M. Abdelrahman, Bakheet E. M. Elsadek +2 more
2017Bioorganic chemistry (Print)49 citations
Semantic Scholar
Design and synthesis of pyrazolo[3,4-d]pyrimidines: Nitric oxide releasing compounds targeting hepatocellular carcinoma.
Y. Elshaier, Mohamed A. Shaaban, Mohammed K. Abd El Hamid, M. Abdelrahman +3 more
2017Bioorganic & Medicinal Chemistry42 citations
Semantic Scholar
Synthesis and Biological Evaluation of Indole-2-Carboxamides with Potent Apoptotic Antiproliferative Activity as EGFR/CDK2 Dual Inhibitors
L. Al-Wahaibi, Yaser A. Mostafa, M. Abdelrahman, Ali H. El-Bahrawy +2 more
2022Pharmaceuticals39 citations Open access
Semantic Scholar
Novel quinoline derivatives carrying nitrones/oximes nitric oxide donors: Design, synthesis, antiproliferative and caspase‐3 activation activities
Mahmoud S. Abdelbaset, Mohamed Abdel-Aziz, G. Abuo-Rahma, M. Abdelrahman +2 more
2018Archiv der Pharmazie34 citations
Semantic Scholar
Design, synthesis and pharmacophoric model building of new 3‐alkoxymethyl/3‐phenyl indole‐2‐carboxamides with potential antiproliferative activity
M. Abdelrahman, Ahmed S. Aboraia, B. Youssif, Bakheet E. M. Elsadek
2017Chemical Biology and Drug Design34 citations
Semantic Scholar
Novel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects.
O. Hendawy, H. Gomaa, Sami I. Alzarea, M. Alshammari +6 more
2021Bioorganic chemistry (Print)27 citations Open access
Semantic Scholar
Development of indole sulfonamides as cannabinoid receptor negative allosteric modulators.
I. Greig, Gemma L. Baillie, M. Abdelrahman, Laurent Trembleau +1 more
2016Bioorganic & Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFRT790M/BRAFV600E Pathways
L. Al-Wahaibi, Anber F. Mohammed, M. Abdelrahman, Laurent Trembleau +1 more
2023Molecules23 citations Open access
Semantic Scholar
Receptor conformational change induces fluoride binding despite competitive water binding.
L. Trembleau, Tim A. D. Smith, M. Abdelrahman
2013Chemical Communications22 citations
Semantic Scholar
New potent ciprofloxacin-uracil conjugates as DNA gyrase and topoisomerase IV inhibitors against methicillin-resistant Staphylococcus aureus.
Mohamed Samir, M. Ramadan, M. Abdelrahman, Mohammed A. I. Elbastawesy +3 more
2022Bioorganic & Medicinal Chemistry20 citations Open access
Semantic Scholar
Design, synthesis, apoptotic, and antiproliferative effects of 5-chloro-3- (2-methoxyvinyl)-indole-2-carboxamides and pyrido[3,4-b]indol-1-ones as potent EGFRWT/EGFRT790M inhibitors
L. Al-Wahaibi, Anber F. Mohammed, Fatema El-Zahraa S. Abdel Rahman, M. Abdelrahman +3 more
2023Journal of Enzyme Inhibition and Medicinal Chemistry18 citations Open access
Semantic Scholar
Discovery of novel oxazole-based macrocycles as anti-coronaviral agents targeting SARS-CoV-2 main protease
L. Al-Wahaibi, A. Mostafa, Yaser A. Mostafa, Ola F Abou-Ghadir +12 more
2021Bioorganic chemistry (Print)18 citations Open access
Semantic Scholar
Synthesis and anti-mycobacterial activity of 4-(4-phenyl-1H-1,2,3-triazol-1-yl)salicylhydrazones: revitalizing an old drug
H. Abdu‐Allah, B. Youssif, M. Abdelrahman, Mohammed K. Abdel-Hamid +4 more
2016Archives of pharmacal research17 citations
Semantic Scholar
Design, synthesis, and biological evaluation of new series of pyrrol-2(3H)-one and pyridazin-3(2H)-one derivatives as tubulin polymerization inhibitors.
Mahmoud S. Abdelbaset, M. Abdelrahman, S. N. I. Bukhari, A. Gouda +3 more
2020Bioorganic chemistry (Print)16 citations
Semantic Scholar
Design, Synthesis, and Biological Evaluation of Indole-2-carboxamides as Potential Multi-Target Antiproliferative Agents
L. Al-Wahaibi, Anber F. Mohammed, M. Abdelrahman, Laurent Trembleau +1 more
2023Pharmaceuticals15 citations Open access
Semantic Scholar
Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity
L. Al-Wahaibi, Hesham A Abou-Zied, M. Abdelrahman, Martha M. Morcoss +3 more
2024Frontiers in Chemistry13 citations Open access
Semantic Scholar
A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models
C. Mielnik, K. Sugamori, David B. Finlay, H. Thorpe +14 more
2020Neuropsychopharmacology11 citations Open access
Semantic Scholar
A comparison of oblique subcostal transversus abdominis plane block versus thoracic paravertebral block for postoperative analgesia after open cholecystectomy
G. Kamhawy, E. Eltaher, M. Abdelrahman
201711 citations Open access
Semantic Scholar
3,7-bis-benzylidene hydrazide ciprofloxacin derivatives as promising antiproliferative dual TOP I & TOP II isomerases inhibitors.
Mohamed Samir, M. Ramadan, M. Abdelrahman, Mahmoud S. Abdelbaset +3 more
2021Bioorganic chemistry (Print)10 citations
Semantic Scholar
Discovery of new 5-substituted-indole-2-carboxamides as dual epidermal growth factor receptor (EGFR)/cyclin dependent kinase-2 (CDK2) inhibitors with potent antiproliferative action.
F. Mohamed, Saleha Y. M. Alakilli, E. E. El Azab, F. Baawad +9 more
2023RSC Medicinal Chemistry9 citations Open access
Semantic Scholar
Pyridazinones and pyrrolones as promising Scaffolds in Medicinal Chemistry
Mahmoud S. Abdelbaset, Mohamed Abdel-Aziz, G. Abuo-Rahma, M. Ramadan +1 more
2018Journal of advanced Biomedical and Pharmaceutical Sciences9 citations Open access
Semantic Scholar
Microwave assisted synthesis, biological assessment and in-silico studies of some new 5,5′-(phenylmethylene)bisuracil and dihydropyrido[2,3-d:6,5-d']dipyrimidine derivatives as selective COX-2 inhibitors with potential anti-inflammatory activities
A. Hayallah, Mohamed A. Shaaban, M. Abdelrahman, Ibrahim M. Salem +5 more
2025Journal of Molecular Structure8 citations
Semantic Scholar
New Ciprofloxacin–Pyrazolopyrimidine Hybrids as Topoisomerase IV and Gyrase Inhibitors against MRSA AUMC 261
Mohamed Samir, Mohamed Ramadan, M. Abdelrahman, Mahmoud S. Abdelbaset +3 more
2024ChemistrySelect2 citations
Semantic Scholar
Analgesic Efficacy of Ultrasound Guided Quadratus Lumborum Block and FasciaI liaca Compartment Block for Patient Schedualed for Dynamic Hip Screw Surgery
M. Elsayed, M. Hasanin, R. Kamel, M. Abdelrahman
2021Benha Journal of Applied Sciences2 citations Open access
Semantic Scholar
Effect of Adding Fentanyl to Bupivacaine in Femoral Nerve Block for Post-Operative Pain in Patient Subjected to Total Knee Replacement Guided by Ultrasound
Alaa Ali M. Elzohry, K. M. Morsy, F. Askar, M. Abdelrahman +1 more
20192 citations
Semantic Scholar
Synthesis, cytotoxicity, and docking study of novel 1-naphthyl-5-aryl-1H-1,2,4-triazole-3-carboxamides
Islam Zaki, M. Ramadan, M. Abdelrahman, Omar M. Aly
2017Chemical Monthly2 citations
Semantic Scholar
Synthesis and Biological Evaluation of Some New 1,2,3-Triazole Derivatives As Anti-microbial Agents
Bahaa G. M. Youssif, M. Abdelrahman
20162 citations Open access
Semantic Scholar
DESIGN, SYNTHESIS AND COX1/2 INHIBITORY ACTIVITY OF NEW QUINAZOLINE-5-ONE DERIVATIVES
Ahmed S. Aboraia, Mohammed A. Hara, M. Abdelrahman, Mohamed M. Amin +1 more
20171 citations Open access
Semantic Scholar
SYNTHESIS OF NOVEL PYRAZOLE DERIVATIVES BEARING 1,2,4-TRIAZOLE MOIETY AS POTENTIAL ANTICANCER AGENTS
M. Abdelrahman, Mamdouh M. Ali
20161 citations Open access
Semantic Scholar
Synthesis, biological evaluation and in silico ADME predictions of some new coumarin-acetamide derivatives as potent anti-inflammatory agents
Mohammed A. I. Elbastawesy, Martha M. Morcoss, M. Abdelrahman, B. Youssif +1 more
2021Bulletin of Pharmaceutical Sciences. Assiut0 citations Open access
Semantic Scholar
Benha Journal of Applied Sciences (BJAS) print : ISSN 2356–9751 Vol.(2) Issue(1) 0ct.(2021), 1-5 online : ISSN 2356–976x http://bjas.bu.edu.eg
M. Elsayed, M. Hasanin, R. Kamel, M. Abdelrahman
20210 citations
Semantic Scholar
Synoxazolidinone C: A Bicyclic Member of the Synoxazolidinone Family with Antibacterial and Anticancer Activities.
Margey Tadesse, J. Svenson, M. Jaspars, Morten B. Stroem +6 more
20110 citations
Semantic Scholar
Design, synthesis and SAR of novel allosteric modulators of the Cannabinoid CBI receptor
M. Abdelrahman
20100 citations
Semantic Scholar

Frequent co-authors

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B. Youssif×21
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B. Youssif — researcher profile on SciRah
Laurent Trembleau×13
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Laurent Trembleau — researcher profile on SciRah
G. Abuo-Rahma×10
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G. Abuo-Rahma — researcher profile on SciRah
Mohamed Abdel-Aziz×8
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Mohamed Abdel-Aziz — researcher profile on SciRah

×7

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L. Al-Wahaibi — researcher profile on SciRah

Mahmoud S. Abdelbaset×7

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Mahmoud S. Abdelbaset — researcher profile on SciRah

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H. Gomaa — researcher profile on SciRah

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M. Ramadan — researcher profile on SciRah

Ahmed H. Abdelazeem×5

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Ahmed H. Abdelazeem — researcher profile on SciRah

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A. Gouda — researcher profile on SciRah

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F. Mohamed — researcher profile on SciRah

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M. Mohamed — researcher profile on SciRah