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A. Cobitz · SciRah

Researcher profile · Semantic Scholar

A. Cobitz

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A. Cobitz — researcher profile on SciRah

h-index: 24
Works: 73
Citations: 2,150

Most-cited papers

Improving metabolic control leads to better working memory in adults with type 2 diabetes.
C. Ryan, M. Freed, J. Rood, A. Cobitz +2 more
2006Diabetes Care309 citations
Semantic Scholar
Four-Week Studies of Oral Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor GSK1278863 for Treatment of Anemia.
L. Holdstock, A. Meadowcroft, R. Maier, Brendan Johnson +5 more
2016Journal of the American Society of Nephrology186 citations Open access
Semantic Scholar
Daprodustat for the Treatment of Anemia in Patients Not Undergoing Dialysis.
A. Singh, K. Carroll, J. McMurray, S. Solomon +18 more
2021New England Journal of Medicine185 citations Open access
Semantic Scholar
Daprodustat for the Treatment of Anemia in Patients Undergoing Dialysis.
A. Singh, K. Carroll, V. Perkovic, S. Solomon +18 more
2021New England Journal of Medicine159 citations Open access
Semantic Scholar
Daprodustat for anemia: a 24-week, open-label, randomized controlled trial in participants on hemodialysis
A. Meadowcroft, Borut Cizman, L. Holdstock, N. Biswas +6 more
2018Clinical Kidney Journal106 citations Open access
Semantic Scholar
Rosiglitazone decreases bone mineral density and increases bone turnover in postmenopausal women with type 2 diabetes mellitus.
J. Bilezikian, R. Josse, R. Eastell, E. Lewiecki +8 more
2013Journal of Clinical Endocrinology and Metabolism103 citations
Semantic Scholar
Efficacy and Safety of Daprodustat Compared with Darbepoetin Alfa in Japanese Hemodialysis Patients with Anemia: A Randomized, Double-Blind, Phase 3 Trial.
T. Akizawa, M. Nangaku, Taeko Yonekawa, Nobuhiko Okuda +5 more
2020American Society of Nephrology. Clinical Journal101 citations Open access
Semantic Scholar
Effects of Daprodustat, a Novel Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor on Anemia Management in Japanese Hemodialysis Subjects
T. Akizawa, Y. Tsubakihara, M. Nangaku, Y. Endo +7 more
2016American Journal of Nephrology100 citations
Semantic Scholar
Daprodustat for anemia: a 24-week, open-label, randomized controlled trial in participants with chronic kidney disease
L. Holdstock, B. Čižman, A. Meadowcroft, N. Biswas +6 more
2018Clinical Kidney Journal74 citations Open access
Semantic Scholar
Daprodustat Compared with Epoetin Beta Pegol for Anemia in Japanese Patients Not on Dialysis: A 52-Week Randomized Open-Label Phase 3 Trial
M. Nangaku, T. Hamano, T. Akizawa, Y. Tsubakihara +7 more
2021American Journal of Nephrology61 citations Open access
Semantic Scholar
Efficacy and Safety of Daprodustat for Treatment of Anemia of Chronic Kidney Disease in Incident Dialysis Patients
Ashutosh Kumar Singh, B. Čižman, K. Carroll, J. McMurray +19 more
2022JAMA Internal Medicine59 citations Open access
Semantic Scholar
Cardiovascular Event Rates Among Hemodialysis Patients Across Geographical Regions—A Snapshot From The Dialysis Outcomes and Practice Patterns Study (DOPPS)
H. Stirnadel-Farrant, A. Karaboyas, B. Čižman, B. Bieber +4 more
2019Kidney International Reports48 citations Open access
Semantic Scholar
Characterization of chronic and acute ESA hyporesponse: a retrospective cohort study of hemodialysis patients
S. Sibbel, C. Koro, S. Brunelli, A. Cobitz
2015BMC Nephrology46 citations Open access
Semantic Scholar
A 24‐Week Anemia Correction Study of Daprodustat in Japanese Dialysis Patients
Y. Tsubakihara, T. Akizawa, M. Nangaku, T. Onoue +4 more
2020Therapeutic apheresis and dialysis42 citations
Semantic Scholar
A retrospective evaluation of congestive heart failure and myocardial ischemia events in 14 237 patients with type 2 diabetes mellitus enrolled in 42 short‐term, double‐blind, randomized clinical studies with rosiglitazone
A. Cobitz, A. Zambanini, M. Sowell, M. Heise +4 more
2008Pharmacoepidemiology and Drug Safety39 citations
Semantic Scholar
An Exploratory Study of Daprodustat in Erythropoietin-Hyporesponsive Subjects
B. Čižman, A. Sykes, G. Paul, S. Zeig +1 more
2018Kidney International Reports37 citations Open access
Semantic Scholar
A randomized, 29-day, dose-ranging, efficacy and safety study of daprodustat, administered three times weekly in patients with anemia on hemodialysis
C. Bailey, S. Caltabiano, A. Cobitz, Chun Huang +2 more
2019BMC Nephrology36 citations Open access
Semantic Scholar
Three Times Weekly Dosing of Daprodustat versus Conventional Epoetin for Treatment of Anemia in Hemodialysis Patients
D. Coyne, Ashutosh Kumar Singh, R. Lopes, C. Bailey +10 more
2022American Society of Nephrology. Clinical Journal34 citations Open access
Semantic Scholar
Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy: A Consensus Statement of the American Diabetes Association and the European Association for the Study of Diabetes
A. Cobitz, P. Ambery
2009Diabetes Care34 citations Open access
Semantic Scholar
Reduction of intramyocellular lipid following short-term rosiglitazone treatment in Zucker fatty rats: an in vivo nuclear magnetic resonance study.
B. Jucker, T. Schaeffer, R. Haimbach, M. Mayer +4 more
2003Metabolism: Clinical and Experimental33 citations
Semantic Scholar
The ASCEND-NHQ trial found positive effects of daprodustat on hemoglobin and quality of life in patients with non-dialysis-dependent chronic kidney disease.
Kirsten L. Johansen, A. Cobitz, Ashutosh Kumar Singh, I. Macdougall +14 more
2023Kidney International31 citations Open access
Semantic Scholar
A 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study of the efficacy and tolerability of combination therapy with rosiglitazone and sulfonylurea in African American and Hispanic American patients with type 2 diabetes inadequately controlled with sulfonylurea mon
J. Davidson, S. Mcmorn, B. Waterhouse, A. Cobitz
2007Clinical Therapeutics29 citations
Semantic Scholar
Normalization of skeletal muscle glycogen synthesis and glycolysis in rosiglitazone-treated Zucker fatty rats: an in vivo nuclear magnetic resonance study.
B. Jucker, T. Schaeffer, R. Haimbach, T. McIntosh +7 more
2002Diabetes26 citations Open access
Semantic Scholar
Rosiglitazone increases LDL particle size and buoyancy and decreases C-reactive protein in patients with type 2 diabetes on statin therapy
Dahong Yu, S. J. Murdoch, S. Parikh, S. Marcovina +3 more
2006Diabetes & vascular disease research24 citations Open access
Semantic Scholar
Reductions in biomarkers of cardiovascular risk in type 2 diabetes with rosiglitazone added to metformin compared with dose escalation of metformin: an EMPIRE trial sub-study*
B. Goldstein, P. Weissman, M. Wooddell, B. Waterhouse +1 more
2006Current Medical Research and Opinion21 citations
Semantic Scholar
The drug interaction potential of daprodustat when coadministered with pioglitazone, rosuvastatin, or trimethoprim in healthy subjects
S. Caltabiano, K. Mahar, Karyn J. Lister, D. Tenero +3 more
2018Pharmacology Research & Perspectives20 citations Open access
Semantic Scholar
Effect of renal function and dialysis modality on daprodustat and predominant metabolite exposure
S. Caltabiano, B. Čižman, Olivia Burns, K. Mahar +4 more
2019Clinical Kidney Journal19 citations Open access
Semantic Scholar
HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury
A. Billin, Samuel E Honeycutt, Alan McDougal, J. P. Kerr +15 more
2018Skeletal Muscle17 citations Open access
Semantic Scholar
Efficacy and safety of daprodustat in Japanese peritoneal dialysis patients
H. Kanai, M. Nangaku, Reiko Nagai, Nobuhiko Okuda +4 more
2021Therapeutic apheresis and dialysis16 citations Open access
Semantic Scholar
Study design and baseline characteristics of patients on dialysis in the ASCEND-D trial
A. Singh, A. Blackorby, B. Čižman, K. Carroll +16 more
2021Nephrology, Dialysis and Transplantation16 citations Open access
Semantic Scholar
Anemia and mortality in patients with nondialysis-dependent chronic kidney disease
H. Stirnadel-Farrant, Jia-Cong Luo, L. Kler, B. Čižman +3 more
2018BMC Nephrology16 citations Open access
Semantic Scholar
Regional Variation of Erythropoiesis-Stimulating Agent Hyporesponsiveness in the Global Daprodustat Dialysis Study (ASCEND-D)
I. Macdougall, A. Meadowcroft, A. Blackorby, B. Čižman +8 more
2023American Journal of Nephrology14 citations Open access
Semantic Scholar
Analysis of on-treatment cancer safety events with daprodustat versus conventional erythropoiesis-stimulating agents - post hoc analyses of the ASCEND-ND and ASCEND-D trials.
Ashutosh Kumar Singh, F. M. Mc Causland, B. Claggett, C. Wanner +14 more
2022Nephrology, Dialysis and Transplantation14 citations Open access
Semantic Scholar
Clinical Pharmacokinetics of Daprodustat: Results of an Absorption, Distribution, and Excretion Study With Intravenous Microtracer and Concomitant Oral Doses for Bioavailability Determination
K. Mahar, S. Caltabiano, S. Andrews, B. Ramanjineyulu +6 more
2021Clinical pharmacology in drug development12 citations Open access
Semantic Scholar
Causes of death in patients with chronic kidney disease: insights from the ASCEND-D and ASCEND-ND cardiovascular outcomes trials
A. Singh, A. Acharya, K. Carroll, R. Lopes +11 more
2022European Heart Journal10 citations Open access
Semantic Scholar
A Randomized, Placebo‐ and Positive‐Controlled, Single‐Dose, Crossover Thorough QT/QTc Study Assessing the Effect of Daprodustat on Cardiac Repolarization in Healthy Subjects
S. Caltabiano, J. Collins, G. Serbest, L. Morgan +3 more
2017Clinical pharmacology in drug development10 citations
Semantic Scholar
Are the metabolic effects of rosiglitazone influenced by baseline glycaemic control?
B. Goldstein, A. Cobitz, L. Hand, Hongzi Chen
2003Current Medical Research and Opinion10 citations
Semantic Scholar
Safety of daprodustat in patients with anemia of chronic kidney disease: A pooled analysis of phase 3 studies in Japan
M. Nangaku, T. Akizawa, Takashi Nagakubo, Taeko Yonekawa +3 more
2022Therapeutic apheresis and dialysis9 citations Open access
Semantic Scholar
Pharmacokinetics of Daprodustat and Metabolites in Individuals with Normal and Impaired Hepatic Function
K. Mahar, B. Shaddinger, B. Ramanjineyulu, S. Andrews +3 more
2022Clinical pharmacology in drug development8 citations Open access
Semantic Scholar
Evaluation of Quantitative Computed Tomography Cortical Hip Quadrant in a Clinical Trial With Rosiglitazone: A Potential New Study Endpoint.
Colin G. Miller, C. Bogado, A. Nino, A. Northcutt +7 more
2016Journal of clinical densitometry7 citations
Semantic Scholar
Mechanism of action study to evaluate the effect of rosiglitazone on bone in postmenopausal women with type 2 diabetes mellitus: rationale, study design and baseline characteristics
L. Fitzpatrick, J. Bilezikian, M. Wooddell, G. Paul +6 more
2011Journal of Drug Assessment6 citations Open access
Semantic Scholar
Effects of Daprodustat on Hemoglobin and Quality of Life in Patients with CKD: Results of the ASCEND-NHQ Randomized, Double-Blind, Placebo-Controlled Trial
K. Johansen, A. Cobitz, Renato D. Lopes, Ajay K. Singh +10 more
2021Journal of the American Society of Nephrology5 citations
Semantic Scholar
MO530: Daprodustat is not Associated With an Increased Risk of Cancer: Results From the ASCEND-D and ASCEND-ND Trials
Ajay K. Singh, C. Wanner, Andrzej Jan Wiecek, A. Blackorby +3 more
2022Nephrology, Dialysis and Transplantation3 citations
Semantic Scholar
The ASCEND-ND trial: study design and participant characteristics
V. Perkovic, A. Blackorby, B. Čižman, K. Carroll +18 more
2021Nephrology, Dialysis and Transplantation3 citations Open access
Semantic Scholar
1124-192 Rosiglitazone reduces novel biomarkers of cardiovascular disease in subjects with type 2 diabetes mellitus already on statin therapy
J. Brunzell, S. Marcovina, Dahong Yu, A. Cobitz +3 more
20043 citations Open access
Semantic Scholar
SaO036Efficacy and safety of daprodustat compared with darbepoetin alfa in Japanese hemodialysis patients with anemia: a randomized, double-blind, phase 3 trial
T. Akizawa, M. Nangaku, Taeko Yonekawa, Nobuhiko Okuda +6 more
2019Nephrology, Dialysis and Transplantation2 citations
Semantic Scholar
STEADY-STATE PHARMACOKINETICS OF GSK1278863 AND METABOLITES IN SUBJECTS WITH NORMAL AND IMPAIRED RENAL FUNCTION
S. Yapa, Brendan Johnson, R. Ravindranath, S. Caltabiano +1 more
20152 citations
Semantic Scholar
Commentary on ‘case series of liver failure associated with rosiglitazone and pioglitazone’ by Floyd et al.
S. Osei, Carol E. Koro, A. Cobitz, Nikheel S. Kolatkar +1 more
2009Pharmacoepidemiology and Drug Safety2 citations
Semantic Scholar
Phosphorylation of RAS 1 and RAS 2 proteins in Saccharomyces cerevisiae
A. Cobitz, Elizabeth H. Yim, W. Brown, Charles M. Perou +1 more
2 citations
Semantic Scholar
ASCEND-TD: A Randomized, Double-Blind, Active-Controlled Study of Daprodustat Administered Three Times Weekly in Hemodialysis Patients
D. Coyne, Ajay K. Singh, Renato D. Lopes, Christine K. Bailey +10 more
2021Journal of the American Society of Nephrology1 citations
Semantic Scholar

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B. Čižman — researcher profile on SciRah
A. Meadowcroft×11
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