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M. Kovács · SciRah

Researcher profile · Semantic Scholar

M. Kovács

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M. Kovács — researcher profile on SciRah

h-index: 31
Works: 114
Citations: 4,116

Most-cited papers

Load-dependent mechanism of nonmuscle myosin 2
M. Kovács, K. Thirumurugan, P. Knight, J. Sellers
2007Proceedings of the National Academy of Sciences of the United States of America249 citations Open access
Semantic Scholar
Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis
Xue-Fei Ma, M. Kovács, M. Conti, Aibing Wang +3 more
2012Proceedings of the National Academy of Sciences of the United States of America140 citations Open access
Semantic Scholar
Disease-associated Mutations and Alternative Splicing Alter the Enzymatic and Motile Activity of Nonmuscle Myosins II-B and II-C*
Kye-Young Kim, M. Kovács, S. Kawamoto, J. Sellers +1 more
2005Journal of Biological Chemistry121 citations Open access
Semantic Scholar
Phase separation by ssDNA binding protein controlled via protein−protein and protein−DNA interactions
Gábor M. Harami, Z. Kovács, R. Pancsa, J. Pálinkás +4 more
2019Proceedings of the National Academy of Sciences of the United States of America120 citations Open access
Semantic Scholar
Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Yuting Yang, S. Gourinath, M. Kovács, L. Nyitray +7 more
2007Structure112 citations Open access
Semantic Scholar
Targeting Myosin by Blebbistatin Derivatives: Optimization and Pharmacological Potential.
A. Rauscher, M. Gyimesi, M. Kovács, A. Málnási-Csizmadia
2018TIBS -Trends in Biochemical Sciences. Regular ed94 citations
Semantic Scholar
From keys to bulldozers: expanding roles for winged helix domains in nucleic-acid-binding proteins.
Gábor M. Harami, M. Gyimesi, M. Kovács
2013TIBS -Trends in Biochemical Sciences. Regular ed88 citations
Semantic Scholar
Kinetic Mechanism of Human dUTPase, an Essential Nucleotide Pyrophosphatase Enzyme*
J. Tóth, B. Varga, M. Kovács, A. Málnási-Csizmadia +1 more
2007Journal of Biological Chemistry71 citations Open access
Semantic Scholar
A Single Mutation in a Tunnel to the Active Site Changes the Mechanism and Kinetics of Product Release in Haloalkane Dehalogenase LinB*
L. Biedermannová, Z. Prokop, Artur Góra, E. Chovancová +3 more
2012Journal of Biological Chemistry67 citations Open access
Semantic Scholar
Dimerized Drosophila myosin VIIa: a processive motor.
Yi Yang, M. Kovács, T. Sakamoto, Fang Zhang +2 more
2006Proceedings of the National Academy of Sciences of the United States of America67 citations
Semantic Scholar
Myosin V from Drosophila Reveals Diversity of Motor Mechanisms within the Myosin V Family*
J. Tóth, M. Kovács, Fei Wang, L. Nyitray +1 more
2005Journal of Biological Chemistry53 citations Open access
Semantic Scholar
Emerging complex pathways of the actomyosin powerstroke
A. Málnási-Csizmadia, M. Kovács
2010TIBS -Trends in Biochemical Sciences. Regular ed51 citations Open access
Semantic Scholar
Human Myosin Vc Is a Low Duty Ratio, Nonprocessive Molecular Motor*
Y. Takagi, Yi Yang, I. Fujiwara, Damon T. Jacobs +3 more
2008Journal of Biological Chemistry50 citations Open access
Semantic Scholar
Mechanism of Action of Myosin X, a Membrane-associated Molecular Motor*
M. Kovács, Fei Wang, J. Sellers
2005Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein
G. Gógl, A. Alexa, B. Kiss, G. Katona +4 more
2015Journal of Biological Chemistry48 citations Open access
Semantic Scholar
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke
Balázs Takács, N. Billington, M. Gyimesi, B. Kintses +3 more
2010Proceedings of the National Academy of Sciences of the United States of America48 citations Open access
Semantic Scholar
Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA
M. Gyimesi, Kata Sarlós, M. Kovács
2010Nucleic Acids Research45 citations Open access
Semantic Scholar
Switch 1 Mutation S217A Converts Myosin V into a Low Duty Ratio Motor*
É. Forgács, T. Sakamoto, Suzanne Cartwright, B. Belknap +5 more
2009Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Azidoblebbistatin, a photoreactive myosin inhibitor
Miklos Kepiro, Boglarka H. Varkuti, A. Bodor, G. Hegyi +3 more
2012Proceedings of the National Academy of Sciences of the United States of America44 citations Open access
Semantic Scholar
Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination
Gábor M. Harami, Yeonee Seol, Junghoon In, Veronika Ferencziová +9 more
2017Proceedings of the National Academy of Sciences of the United States of America43 citations Open access
Semantic Scholar
Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state
M. Špírek, Jarmila Mlčoušková, O. Belan, M. Gyimesi +5 more
2018Nucleic Acids Research41 citations Open access
Semantic Scholar
Affinity, Avidity, and Kinetics of Target Sequence Binding to LC8 Dynein Light Chain Isoforms*
L. Radnai, P. Rapali, Zsuzsanna Hódi, Dániel Süveges +8 more
2010Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Myosin VIIB from Drosophila Is a High Duty Ratio Motor*
Yi Yang, M. Kovács, Qian Xu, John B. Anderson +1 more
2005Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Single residue variation in skeletal muscle myosin enables direct and selective drug targeting for spasticity and muscle stiffness
M. Gyimesi, Ádám I. Horváth, Demeter Túrós, S. K. Suthar +14 more
2020Cell37 citations Open access
Semantic Scholar
Complex activities of the human Bloom's syndrome helicase are encoded in a core region comprising the RecA and Zn-binding domains
M. Gyimesi, Gábor M. Harami, Kata Sarlós, E. Hazai +2 more
2012Nucleic Acids Research30 citations Open access
Semantic Scholar
RecQ helicase translocates along single-stranded DNA with a moderate processivity and tight mechanochemical coupling
Kata Sarlós, M. Gyimesi, M. Kovács
2012Proceedings of the National Academy of Sciences of the United States of America29 citations Open access
Semantic Scholar
Kinetic mechanism of myosinV-S1 using a new fluorescent ATP analogue.
É. Forgács, Suzanne Cartwright, M. Kovács, T. Sakamoto +4 more
2006Biochemistry29 citations
Semantic Scholar
RecQ helicase triggers a binding mode change in the SSB–DNA complex to efficiently initiate DNA unwinding
Maria Mills, Gábor M. Harami, Yeonee Seol, M. Gyimesi +4 more
2017Nucleic Acids Research28 citations Open access
Semantic Scholar
Myosin cleft closure determines the energetics of the actomyosin interaction
Balázs Takács, E. O'Neall-Hennessey, C. Hetényi, J. Kardos +2 more
2011The FASEB Journal26 citations Open access
Semantic Scholar
Selective Perturbation of the Myosin Recovery Stroke by Point Mutations at the Base of the Lever Arm Affects ATP Hydrolysis and Phosphate Release*
A. Málnási-Csizmadia, J. Tóth, D. S. Pearson, C. Hetényi +4 more
2007Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Live cell superresolution-structured illumination microscopy imaging analysis of the intercellular transport of microvesicles and costimulatory proteins via nanotubes between immune cells
H. Halász, Alireza Ghadaksaz, T. Madarász, K. Huber +8 more
2018Methods and Applications in Fluorescence23 citations Open access
Semantic Scholar
The HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling
Gábor M. Harami, Nikolett T. Nagy, Máté Martina, K. Neuman +1 more
2015Scientific Reports21 citations Open access
Semantic Scholar
A Nucleotide-dependent and HRDC Domain-dependent Structural Transition in DNA-bound RecQ Helicase*
Z. Kocsis, Kata Sarlós, Gábor M. Harami, Máté Martina +1 more
2014Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Visualization of human Bloom's syndrome helicase molecules bound to homologous recombination intermediates
M. Gyimesi, Ricardo H. Pires, N. Billington, Kata Sarlós +4 more
2013The FASEB Journal19 citations Open access
Semantic Scholar
Myosin and Tropomyosin Stabilize the Conformation of Formin-nucleated Actin Filaments
Z. Ujfalusi, M. Kovács, Nikolett T. Nagy, Szilvia Barkó +4 more
2012Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Enzyme kinetics above denaturation temperature: a temperature-jump/stopped-flow apparatus.
B. Kintses, Zoltán Simon, M. Gyimesi, Julia I. Toth +4 more
2006Biophysical Journal18 citations Open access
Semantic Scholar
The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom’s syndrome helicase for efficient disruption of D-loops
Gábor M. Harami, J. Pálinkás, Yeonee Seol, Z. Kovács +4 more
2022Nature Communications16 citations Open access
Semantic Scholar
Functional adaptation of the switch‐2 nucleotide sensor enables rapid processive translocation by myosin‐5
Nikolett T. Nagy, T. Sakamoto, Balázs Takács, M. Gyimesi +4 more
2010The FASEB Journal14 citations Open access
Semantic Scholar
Diversity of structural behavior in vertebrate conventional myosins complexed with actin.
H. Iwamoto, K. Oiwa, M. Kovács, J. Sellers +5 more
2007Journal of Molecular Biology14 citations Open access
Semantic Scholar
Biological, Biochemical, and Kinetic Effects of Mutations of the Cardiomyopathy Loop of Dictyostelium Myosin II
Xiong Liu, Shi Shu, M. Kovács, E. Korn
2005Journal of Biological Chemistry13 citations Open access
Semantic Scholar
Homology sensing via non-linear amplification of sequence-dependent pausing by RecQ helicase
Yeonee Seol, Gábor M. Harami, M. Kovács, K. Neuman
2019eLife12 citations Open access
Semantic Scholar
Bloom syndrome helicase contributes to germ line development and longevity in zebrafish
Tamás Annus, Dalma Müller, Bálint Jezsó, György Ullaga +5 more
2021Cell Death and Disease11 citations Open access
Semantic Scholar
Mgs1 protein supports genome stability via recognition of G‐quadruplex DNA structures
Theresa Zacheja, Á. Tóth, Gabor M. Harami, Qian-Lu Yang +4 more
2020The FASEB Journal11 citations Open access
Semantic Scholar
Structural insight into a partially unfolded state preceding aggregation in an intracellular lipid‐binding protein
G. Horváth, L. Biczók, Z. Majer, M. Kovács +3 more
2017The FEBS Journal10 citations
Semantic Scholar
Streamlined determination of processive run length and mechanochemical coupling of nucleic acid motor activities
M. Gyimesi, Kata Sarlós, I. Derényi, M. Kovács
2010Nucleic Acids Research10 citations Open access
Semantic Scholar
Redox-dependent condensation and cytoplasmic granulation by human ssDNA-binding protein-1 delineate roles in oxidative stress response
Gábor M. Harami, J. Pálinkás, Z. Kovács, Bálint Jezsó +8 more
2024bioRxiv7 citations Open access
Semantic Scholar
Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
M. Gyimesi, A. Rauscher, S. K. Suthar, K. Hamow +14 more
2021Journal of Pharmacology and Experimental Therapeutics7 citations Open access
Semantic Scholar
Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion
Ádám I. Horváth, M. Gyimesi, Boglarka H. Varkuti, Miklos Kepiro +5 more
2020Scientific Reports7 citations Open access
Semantic Scholar
Ligand entry in human ileal bile acid-binding protein is mediated by histidine protonation
G. Horváth, O. Egyed, Chang-Guo Tang, M. Kovács +3 more
2019Scientific Reports6 citations Open access
Semantic Scholar
DNA‐dependent phase separation by human SSB2 (NABP1/OBFC2A) protein points to adaptations to eukaryotic genome repair processes
Z. Kovács, Gábor M. Harami, J. Pálinkás, Natalie Kuljanishvili +6 more
2024bioRxiv5 citations Open access
Semantic Scholar

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Kata Sarlós — researcher profile on SciRah

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