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Blythe D. Shepard · SciRah

Researcher profile · Semantic Scholar

Blythe D. Shepard

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Blythe D. Shepard — researcher profile on SciRah

h-index: 14
Works: 47
Citations: 800

Most-cited papers

Sex Differences in Diabetes and Kidney Disease: Mechanisms and Consequences.
Blythe D. Shepard
2019AJP - Renal Physiology109 citations Open access
Semantic Scholar
A Cleavable N-Terminal Signal Peptide Promotes Widespread Olfactory Receptor Surface Expression in HEK293T Cells
Blythe D. Shepard, Niranjana Natarajan, Ryan J. Protzko, Omar W. Acres +1 more
2013PLoS ONE95 citations Open access
Semantic Scholar
Alcohol-induced protein hyperacetylation: mechanisms and consequences.
Blythe D. Shepard, P. Tuma
2009World Journal of Gastroenterology81 citations Open access
Semantic Scholar
Chronic Ethanol Consumption Induces Global Hepatic Protein Hyperacetylation
Blythe D. Shepard, D. Tuma, P. Tuma
2009Alcoholism: Clinical and Experimental Research67 citations Open access
Semantic Scholar
A Renal Olfactory Receptor Aids in Kidney Glucose Handling
Blythe D. Shepard, L. Cheval, Z. Peterlin, S. Firestein +3 more
2016Scientific Reports54 citations Open access
Semantic Scholar
Microtubule acetylation and stability may explain alcohol‐induced alterations in hepatic protein trafficking
Rohan A. Joseph, Blythe D. Shepard, G. Kannarkat, T. M. Rutledge +2 more
2008Hepatology41 citations Open access
Semantic Scholar
Alcohol-induced alterations of the hepatocyte cytoskeleton.
Blythe D. Shepard, P. Tuma
2010World Journal of Gastroenterology39 citations Open access
Semantic Scholar
Alcohol-Induced Alterations in Hepatic Microtubule Dynamics Can Be Explained by Impaired Histone Deacetylase 6 Function
Blythe D. Shepard, Rohan A. Joseph, G. Kannarkat, T. M. Rutledge +2 more
2008Hepatology39 citations Open access
Semantic Scholar
Renal olfactory receptor 1393 contributes to the progression of type 2 diabetes in a diet-induced obesity model.
Blythe D. Shepard, H. Koepsell, Jennifer L. Pluznick
2019AJP - Renal Physiology35 citations Open access
Semantic Scholar
How does your kidney smell? Emerging roles for olfactory receptors in renal function
Blythe D. Shepard, Jennifer L. Pluznick
2015Pediatric nephrology (Berlin, West)30 citations Open access
Semantic Scholar
Renal tubule insulin receptor modestly promotes elevated blood pressure and markedly stimulates glucose reabsorption.
Jonathan M. Nizar, Blythe D. Shepard, Vianna Vo, Vivek Bhalla
2018JCI Insight28 citations Open access
Semantic Scholar
Saving the sweetness: renal glucose handling in health and disease.
Blythe D. Shepard, Jennifer L. Pluznick
2017AJP - Renal Physiology25 citations Open access
Semantic Scholar
Alcohol consumption impairs hepatic protein trafficking: mechanisms and consequences
Blythe D. Shepard, David J. Fernandez, P. Tuma
2010Genes & Nutrition25 citations Open access
Semantic Scholar
The Sensing Liver: Localization and Ligands for Hepatic Murine Olfactory and Taste Receptors
Ryan W. Kurtz, Lily G. Steinberg, Madison Betcher, D. Fowler +1 more
2020Frontiers in Physiology18 citations Open access
Semantic Scholar
Empagliflozin Treatment Attenuates Hepatic Steatosis by Promoting White Adipose Expansion in Obese TallyHo Mice
Ryan Kurtz, Andrew E. Libby, Bryce A. Jones, K. Myakala +14 more
2022International Journal of Molecular Sciences14 citations Open access
Semantic Scholar
GPCRs get Fatty: The Role of G Protein-Coupled Receptor Signaling in the Development and Progression of Nonalcoholic Fatty Liver Disease.
Ryan W. Kurtz, Meghan F Anderman, Blythe D. Shepard
2020American Journal of Physiology - Gastrointestinal and Liver Physiology13 citations Open access
Semantic Scholar
Lysine acetylation induced by chronic ethanol consumption impairs dynamin-mediated clathrin-coated vesicle release
Blythe D. Shepard, D. Tuma, P. Tuma
2012Hepatology13 citations Open access
Semantic Scholar
The Sugar Daddy: The Role of the Renal Proximal Tubule in Glucose Homeostasis.
Zahraa S. Hotait, Julia N. Lo Cascio, Elijah N D Choos, Blythe D. Shepard
2022American Journal of Physiology - Cell Physiology11 citations Open access
Semantic Scholar
Late-onset renal hypertrophy and dysfunction in mice lacking CTRP1
Susana Rodriguez, Hannah C. Little, Parnaz Daneshpajouhnejad, Blythe D. Shepard +10 more
2019The FASEB Journal11 citations Open access
Semantic Scholar
Acid Loading Unmasks Glucose Homeostatic Instability in Proximal-Tubule-Targeted Insulin/Insulin-Like-Growth-Factor-1 Receptor Dual Knockout Mice
A. Aljaylani, Maurice B. Fluitt, Alexandra Piselli, Blythe D. Shepard +2 more
2020Cellular Physiology and Biochemistry10 citations Open access
Semantic Scholar
Roles of sensory receptors in non-sensory organs: the kidney and beyond
Jiaojiao Xu, Blythe D. Shepard, Jennifer L. Pluznick
2025Nature Reviews Nephrology9 citations Open access
Semantic Scholar
The Sniffing Kidney: Roles for Renal Olfactory Receptors in Health and Disease.
Blythe D. Shepard
2021Kidney3609 citations Open access
Semantic Scholar
Renal Metabolome in Obese Mice Treated with Empagliflozin Suggests a Reduction in Cellular Respiration
Surabhi Bangarbale, Blythe D. Shepard, Shivani Bansal, Meth M. Jayatilake +3 more
2022Biomolecules6 citations Open access
Semantic Scholar
Sodium Glucose Transporter, Type 2 (SGLT2) Inhibitors (SGLT2i) and Glucagon-Like Peptide 1-Receptor Agonists: Newer Therapies in Whole-Body Glucose Stabilization.
Blythe D. Shepard, C. Ecelbarger
2021Seminars in Nephrology6 citations
Semantic Scholar
Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a type 1 diabetic mouse model
A. Schiazza, Elizabeth G. Considine, Madison Betcher, Blythe D. Shepard
2021Physiological Reports6 citations Open access
Semantic Scholar
Multi-Modal Diagnostic Imaging of Metabolic Dysfunction-Associated Steatotic Liver Disease: Non-invasive Analyses by Photoacoustic Ultrasound and MRI.
Alissa Keegan, Gayathri Malamal, Yi-Chien Lee, Kyle E. Korolowicz +12 more
2025American Journal of Pathology4 citations Open access
Semantic Scholar
Nascent shifts in renal cellular metabolism, structure, and function due to chronic empagliflozin in prediabetic mice.
Blythe D. Shepard, Jennifer N. Chau, Ryan Kurtz, Avi Z. Rosenberg +11 more
2024American Journal of Physiology - Cell Physiology3 citations Open access
Semantic Scholar
Modulation of Estrogen Receptor Signaling Sensitizes Female Mice to the Development of Diabetes
Julia N. Lo Cascio, Ali Jordan, Meghan F. Anderman, Blythe D. Shepard
2022The FASEB Journal1 citations
Semantic Scholar
Characterizing the impact of SGLT2 inhibition on hepatic inflammation and cellular response in a type 2 diabetic mouse model
Elijah N D Choos, Blythe D. Shepard
2023Physiology0 citations
Semantic Scholar
SGLT2 Inhibition Alters the Hepatic and Circulating Metabolome of Mice Under a High-Milk-Fat Diet
Ileana Mendez Espinoza, Blythe D. Shepard
2023Physiology0 citations
Semantic Scholar
Elucidating the role of renal olfactory receptor 1393 in female Type 1 diabetic mice
Britney Shaw, Ali Jordan, Blythe D. Shepard
2023Physiology0 citations
Semantic Scholar
Localization and functional importance of GPR125 in the liver
Safa Samimi, Ryan Kurtz, Joel Fernandez, Blythe D. Shepard
2023Physiology0 citations
Semantic Scholar
Impact of Dietary Empagliflozin on Renal Cortex Metabolome and Lipidome in Mice
Surabhi Bangarbale, Shivani Bansal, M. Jayatilake, Moshe Levi +2 more
2022The FASEB Journal0 citations
Semantic Scholar
Dietary Empagliflozin Regulates Angiotensin Converting Enzyme 2 (ACE2) and Transmembrane Serine Protease 2 (TMPRSS2) in Kidney Cortex of Mice
Aarenee Greene, A. D. de Souza, Jennifer Chau, Moshe Levi +3 more
2022The FASEB Journal0 citations Open access
Semantic Scholar
Characterizing Murine Diabetic Glucose Metabolism Under Conditions of Attenuated Renal Glucose Reabsorption
Zahraa S. Hotait, Blythe D. Shepard
2022The FASEB Journal0 citations
Semantic Scholar
Renal Olfr1393 may contribute to glucose metabolism
Zahraa S. Hotait, Blythe D. Shepard
2020The FASEB Journal0 citations Open access
Semantic Scholar
Controlling Glucose Handling via Renal Olfr1393 Offers Protection in a Type I Diabetic Mouse Model
Alexis R. Schiazza, Blythe D. Shepard
2019The FASEB Journal0 citations
Semantic Scholar
Identifying and Characterizing Hepatic Sensory Receptors
Ryan Kurtz, Lily G. Steinberg, Blythe D. Shepard
2019The FASEB Journal0 citations
Semantic Scholar
Renal Olfactory Receptor 1393 Contributes to the Progression of Diabetes
Blythe D. Shepard, H. Koepsell, Jennifer L. Pluznick
20180 citations
Semantic Scholar
Renal Olfactory Receptor 1393 May Contribute to the Progression of Diabetic Nephropathy
Blythe D. Shepard, Jennifer L. Pluznick
2017The FASEB Journal0 citations Open access
Semantic Scholar
Deorphanizing Renal Olfactory Receptor 1393
Blythe D. Shepard, Z. Peterlin, S. Firestein, Jennifer L. Pluznick
2016The FASEB Journal0 citations Open access
Semantic Scholar
A Renal Olfactory Receptor Aids in Glucose Handling in the Proximal Tubule
Blythe D. Shepard, L. Cheval, A. Doucet, Jennifer L. Pluznick
20150 citations
Semantic Scholar
Elucidating the role of a renal proximal tubule‐specific olfactory receptor (892.42)
Blythe D. Shepard, L. Cheval, A. Doucet, Jennifer L. Pluznick
20140 citations
Semantic Scholar
An N‐terminal Signal Peptide Increases Total Expression and Enhances Surface Trafficking of Olfactory Receptors (ORs)
Blythe D. Shepard, Niranjana Natarajan, Ryan J. Protzko, Omar W. Acres +1 more
20130 citations
Semantic Scholar
Elucidating the Role of a Renal Proximal Tubule‐Specific Olfactory Receptor
Blythe D. Shepard, L. Cheval, A. Doucet, Jennifer L. Pluznick
20130 citations
Semantic Scholar
Elucidating the role of a renal proximal tubule‐specific olfactory receptor
Blythe D. Shepard, L. Cheval, A. Doucet, Jennifer L. Pluznick
20120 citations
Semantic Scholar
Chronic Alcohol Consumption Leads to Hepatic Lysine Hyperacetylation: Mechanisms and Consequences
Blythe D. Shepard
20110 citations
Semantic Scholar

Frequent co-authors

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Jennifer L. Pluznick×8
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Jennifer L. Pluznick — researcher profile on SciRah
P. Tuma×7
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P. Tuma — researcher profile on SciRah
C. Ecelbarger×7
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C. Ecelbarger — researcher profile on SciRah
Jennifer L. Pluznick×7
Moshe Levi×6
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Moshe Levi — researcher profile on SciRah

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L. Cheval — researcher profile on SciRah

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Ryan Kurtz — researcher profile on SciRah

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D. Tuma — researcher profile on SciRah

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H. Koepsell — researcher profile on SciRah

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A. Doucet — researcher profile on SciRah

Julia N. Lo Cascio×3

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Julia N. Lo Cascio — researcher profile on SciRah

Elijah N D Choos×3

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Elijah N D Choos — researcher profile on SciRah