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T. Lahaye · SciRah

Researcher profile · Semantic Scholar

T. Lahaye

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T. Lahaye — researcher profile on SciRah

h-index: 40
Works: 86
Citations: 10K

Most-cited papers

Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors
J. Boch, H. Scholze, S. Schornack, Angelika Landgraf +5 more
2009Science2,655 citations
Semantic Scholar
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
C. Mussolino, Robert Morbitzer, Fabienne Lütge, N. Dannemann +2 more
2011Nucleic Acids Research758 citations Open access
Semantic Scholar
Plant Pathogen Recognition Mediated by Promoter Activation of the Pepper Bs3 Resistance Gene
Patrick Römer, S. Hahn, T. Jordán, Tina Strauß +2 more
2007Science484 citations
Semantic Scholar
TAL effectors: finding plant genes for disease and defense.
A. Bogdanove, S. Schornack, T. Lahaye
2010Current opinion in plant biology429 citations
Semantic Scholar
A novel class of eukaryotic zinc-binding proteins is required for disease resistance signaling in barley and development in C. elegans.
K. Shirasu, T. Lahaye, Man-Wah Tan, Fasong Zhou +2 more
1999Cell368 citations Open access
Semantic Scholar
A contiguous 66-kb barley DNA sequence provides evidence for reversible genome expansion.
Ken Shirasu, A. Schulman, T. Lahaye, P. Schulze-Lefert
2000Genome Research329 citations Open access
Semantic Scholar
Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors
Robert Morbitzer, Patrick Römer, J. Boch, T. Lahaye
2010Proceedings of the National Academy of Sciences of the United States of America299 citations Open access
Semantic Scholar
Co-incidence of Damage and Microbial Patterns Controls Localized Immune Responses in Roots
Feng Zhou, A. Emonet, Valérie Dénervaud Tendon, Peter Marhavý +3 more
2020Cell246 citations Open access
Semantic Scholar
Assembly of custom TALE-type DNA binding domains by modular cloning
Robert Morbitzer, J. Elsaesser, Jens Hausner, T. Lahaye
2011Nucleic Acids Research205 citations Open access
Semantic Scholar
Xanthomonas axonopodis virulence is promoted by a transcription activator-like effector-mediated induction of a SWEET sugar transporter in cassava.
M. Cohn, R. Bart, Mikel E. Shybut, D. Dahlbeck +6 more
2014Molecular Plant-Microbe Interactions204 citations Open access
Semantic Scholar
Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers
Sebastian Bultmann, Robert Morbitzer, Christine S. Schmidt, Katharina Thanisch +4 more
2012Nucleic Acids Research204 citations Open access
Semantic Scholar
TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity
C. Mussolino, Jamal Alzubi, E. Fine, Robert Morbitzer +4 more
2014Nucleic Acids Research197 citations Open access
Semantic Scholar
The tomato resistance protein Bs4 is a predicted non-nuclear TIR-NB-LRR protein that mediates defense responses to severely truncated derivatives of AvrBs4 and overexpressed AvrBs3.
S. Schornack, A. Ballvora, D. Gürlebeck, Jack R. Peart +5 more
2004The Plant Journal197 citations Open access
Semantic Scholar
Promoter elements of rice susceptibility genes are bound and activated by specific TAL effectors from the bacterial blight pathogen, Xanthomonas oryzae pv. oryzae.
Patrick Römer, Sabine Recht, Tina Strauß, J. Elsaesser +4 more
2010New Phytologist191 citations
Semantic Scholar
Plant disease resistance triggered by pathogen-derived molecules: refined models of specific recognition.
U. Bonas, T. Lahaye
2002Current Opinion in Microbiology184 citations
Semantic Scholar
Quantitative analysis of TALE–DNA interactions suggests polarity effects
Joshua F. Meckler, M. Bhakta, Moon-Soo Kim, R. Ovadia +9 more
2013Nucleic Acids Research168 citations Open access
Semantic Scholar
TAL effectors--pathogen strategies and plant resistance engineering.
J. Boch, U. Bonas, T. Lahaye
2014New Phytologist167 citations
Semantic Scholar
A single plant resistance gene promoter engineered to recognize multiple TAL effectors from disparate pathogens
Patrick Römer, Sabine Recht, T. Lahaye
2009Proceedings of the National Academy of Sciences of the United States of America160 citations Open access
Semantic Scholar
Gene-for-gene-mediated recognition of nuclear-targeted AvrBs3-like bacterial effector proteins.
S. Schornack, Annett Meyer, Patrick Römer, T. Jordán +1 more
2006Journal of plant physiology151 citations
Semantic Scholar
The visible touch: in planta visualization of protein-protein interactions by fluorophore-based methods
Riyaz A. Bhat, T. Lahaye, R. Panstruga
2006Plant Methods138 citations Open access
Semantic Scholar
A Modular Plasmid Assembly Kit for Multigene Expression, Gene Silencing and Silencing Rescue in Plants
A. Binder, J. Lambert, Robert Morbitzer, C. Popp +3 more
2014PLoS ONE136 citations Open access
Semantic Scholar
Metabolomics of tomato xylem sap during bacterial wilt reveals Ralstonia solanacearum produces abundant putrescine, a metabolite that accelerates wilt disease
Tiffany M. Lowe-Power, Connor G. Hendrich, E. von Roepenack-Lahaye, Bin Li +12 more
2017Environmental Microbiology129 citations Open access
Semantic Scholar
Recognition of AvrBs3-Like Proteins Is Mediated by Specific Binding to Promoters of Matching Pepper Bs3 Alleles1[W]
Patrick Römer, Tina Strauß, S. Hahn, H. Scholze +4 more
2009Plant Physiology119 citations Open access
Semantic Scholar
RNA-seq pinpoints a Xanthomonas TAL-effector activated resistance gene in a large-crop genome
Tina Strauß, R. V. van Poecke, Annett Strauß, Patrick Römer +13 more
2012Proceedings of the National Academy of Sciences of the United States of America115 citations Open access
Semantic Scholar
Alternative splicing of transcripts encoding Toll-like plant resistance proteins - what's the functional relevance to innate immunity?
T. Jordán, S. Schornack, T. Lahaye
2002Trends in Plant Science109 citations
Semantic Scholar
TALE-induced bHLH transcription factors that activate a pectate lyase contribute to water soaking in bacterial spot of tomato
Allison R. Schwartz, Robert Morbitzer, T. Lahaye, B. Staskawicz
2017Proceedings of the National Academy of Sciences of the United States of America107 citations Open access
Semantic Scholar
Arabidopsis VIRE2 INTERACTING PROTEIN2 Is Required for Agrobacterium T-DNA Integration in Plants[W]
A. Anand, A. Krichevsky, S. Schornack, T. Lahaye +4 more
2007The Plant Cell Online105 citations Open access
Semantic Scholar
Characterization of AvrHah1, a novel AvrBs3-like effector from Xanthomonas gardneri with virulence and avirulence activity.
S. Schornack, G. Minsavage, R. E. Stall, Jeffrey B. Jones +1 more
2008New Phytologist104 citations
Semantic Scholar
Breaking the DNA-binding code of Ralstonia solanacearum TAL effectors provides new possibilities to generate plant resistance genes against bacterial wilt disease.
Orlando de Lange, Tom Schreiber, Niklas Schandry, J. Radeck +5 more
2013New Phytologist103 citations
Semantic Scholar
p-Coumaroylnoradrenaline, a Novel Plant Metabolite Implicated in Tomato Defense against Pathogens*
E. von Roepenack-Lahaye, M. Newman, S. Schornack, K. Hammond-Kosack +4 more
2003Journal of Biological Chemistry100 citations Open access
Semantic Scholar
A Plant Pathogen Type III Effector Protein Subverts Translational Regulation to Boost Host Polyamine Levels.
Dou-Sheng Wu, E. von Roepenack-Lahaye, Matthias Buntru, Orlando de Lange +9 more
2019Cell Host and Microbe83 citations Open access
Semantic Scholar
Targeting and tracing of specific DNA sequences with dTALEs in living cells
Katharina Thanisch, Katrin Schneider, Robert Morbitzer, I. Solovei +3 more
2013Nucleic Acids Research68 citations Open access
Semantic Scholar
Programmable DNA-binding proteins from Burkholderia provide a fresh perspective on the TALE-like repeat domain
Orlando de Lange, C. Wolf, Jörn Dietze, J. Elsaesser +2 more
2014Nucleic Acids Research55 citations Open access
Semantic Scholar
The Arabidopsis RRS1-R disease resistance gene--uncovering the plant's nucleus as the new battlefield of plant defense?
T. Lahaye
2002Trends in Plant Science52 citations
Semantic Scholar
Targeted introduction of heritable point mutations into the plant mitochondrial genome
Joachim Forner, Dennis Kleinschmidt, E. Meyer, A. Fischer +4 more
2022Nature Plants50 citations Open access
Semantic Scholar
From dead leaf, to new life: TAL effectors as tools for synthetic biology.
Orlando de Lange, A. Binder, T. Lahaye
2014The Plant Journal50 citations
Semantic Scholar
Pacbio sequencing of copper-tolerant Xanthomonas citri reveals presence of a chimeric plasmid structure and provides insights into reassortment and shuffling of transcription activator-like effectors among X. citri strains
A. Gochez, J. Huguet-Tapia, G. Minsavage, Deepak Shantaraj +7 more
2018BMC Genomics49 citations Open access
Semantic Scholar
TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASE-Mediated Generation and Metabolic Analysis of Camalexin-Deficient cyp71a12 cyp71a13 Double Knockout Lines1
Teresa M. Müller, Christoph Böttcher, Robert Morbitzer, Cornelia Götz +3 more
2015Plant Physiology48 citations Open access
Semantic Scholar
Promoter strength influences polyamine metabolism and morphogenic capacity in transgenic rice tissues expressing the oat adc cDNA constitutively
L. Bassie, Matthieu Noury, O. Lepri, T. Lahaye +2 more
2000Transgenic research45 citations
Semantic Scholar
Zinc fingers, TAL effectors, or Cas9-based DNA binding proteins: what's best for targeting desired genome loci?
Annett Strauβ, T. Lahaye
2013Molecular Plant40 citations Open access
Semantic Scholar
Expression levels of avrBs3-like genes affect recognition specificity in tomato Bs4- but not in pepper Bs3-mediated perception.
S. Schornack, K. Peter, U. Bonas, T. Lahaye
2005Molecular Plant-Microbe Interactions40 citations Open access
Semantic Scholar
Agrobacterium-mediated transient expression in citrus leaves: a rapid tool for gene expression and functional gene assay
J. Figueiredo, Patrick Römer, T. Lahaye, J. Graham +2 more
2011Plant Cell Reports38 citations
Semantic Scholar
Host-associated microbe PCR (hamPCR) enables convenient measurement of both microbial load and community composition
D. Lundberg, P. PramojnaAyutthaya, Annett Strauß, Gautam Shirsekar +3 more
2021eLife37 citations Open access
Semantic Scholar
Chromosome landing at the barley Rar1 locus
T. Lahaye, Ken Shirasu, Paul Schulze-Lefert
1998Molecular and General Genetics MGG34 citations
Semantic Scholar
A simple test for the cleavage activity of customized endonucleases in plants
N. Budhagatapalli, Sindy Schedel, M. Gurushidze, S. Pencs +8 more
2016Plant Methods33 citations Open access
Semantic Scholar
Comparison of gene activation by two TAL effectors from Xanthomonas axonopodis pv. manihotis reveals candidate host susceptibility genes in cassava.
M. Cohn, Robert Morbitzer, T. Lahaye, B. Staskawicz
2016Molecular plant pathology32 citations Open access
Semantic Scholar
High-resolution genetic and physical mapping of the Rar1 locus in barley
T. Lahaye, S. Hartmann, S. Töpsch, A. Freialdenhoven +2 more
1998Theoretical and Applied Genetics31 citations
Semantic Scholar
Efficient TALEN‐mediated gene editing in wheat
Ming Luo, Hong-Yu Li, Soma Chakraborty, Robert Morbitzer +7 more
2019Plant Biotechnology Journal29 citations Open access
Semantic Scholar
TALE-Like Effectors Are an Ancestral Feature of the Ralstonia solanacearum Species Complex and Converge in DNA Targeting Specificity
Niklas Schandry, Orlando de Lange, P. Prior, T. Lahaye
2016Frontiers in Plant Science27 citations Open access
Semantic Scholar
Microbial effectors and the role of water and sugar in the infection battle ground.
Farid El Kasmi, D. Horvath, T. Lahaye
2018Current opinion in plant biology26 citations
Semantic Scholar

Frequent co-authors

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Robert Morbitzer×16
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S. Schornack×10
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Patrick Römer×8
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U. Bonas×7
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Orlando de Lange

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Tina Strauß×4

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J. Elsaesser×4

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Annett Strauß×4

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