Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Eneda Toska · SciRah

Researcher profile · Semantic Scholar

Eneda Toska

Share profile

Eneda Toska — researcher profile on SciRah

h-index: 25
Works: 94
Citations: 5,222

Most-cited papers

PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
Antonino Glaviano, A. S. Foo, Hiu Y. Lam, K. C. Yap +23 more
2023Molecular Cancer2,000 citations Open access
Semantic Scholar
PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer
A. Bosch, Zhiqiang Li, A. Bergamaschi, H. Ellis +24 more
2015Science Translational Medicine385 citations Open access
Semantic Scholar
PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D
Eneda Toska, H. Osmanbeyoglu, P. Castel, Carmen Chan +7 more
2017Science252 citations Open access
Semantic Scholar
Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors
N. Vasan, P. Razavi, Jared L. Johnson, H. Shao +23 more
2019Science247 citations Open access
Semantic Scholar
PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition
P. Castel, H. Ellis, R. Bago, Eneda Toska +10 more
2016Cancer Cell225 citations Open access
Semantic Scholar
ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer
Guotai Xu, S. Chhangawala, E. Cocco, P. Razavi +27 more
2020Nature Genetics195 citations Open access
Semantic Scholar
Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation
E. Cocco, A. Schram, Amanda Kulick, S. Misale +25 more
2019Nature Medicine193 citations Open access
Semantic Scholar
The present and future of PI3K inhibitors for cancer therapy
P. Castel, Eneda Toska, J. Engelman, M. Scaltriti
2021Nature Cancer183 citations Open access
Semantic Scholar
Overview of the relevance of PI3K pathway in HR-positive breast cancer
N. Vasan, Eneda Toska, M. Scaltriti
2019Annals of Oncology161 citations Open access
Semantic Scholar
Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma.
P. Mondello, Saber Tadros, Matt Teater, L. Fontán +25 more
2019bioRxiv138 citations Open access
Semantic Scholar
Mechanisms of transcriptional regulation by WT1 (Wilms’ tumour 1)
Eneda Toska, S. Roberts
2014Biochemical Journal125 citations Open access
Semantic Scholar
Cell-autonomous Cxcl1 sustains tolerogenic circuitries and stromal inflammation via neutrophil-derived TNF in pancreatic cancer
A. Bianchi, Iago De Castro Silva, N. Deshpande, Samara P. Singh +27 more
2023Cancer Discovery122 citations Open access
Semantic Scholar
FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer
A. Arruabarrena-Aristorena, J. Maag, Srushti Kittane, Yan-Yan Cai +23 more
2020Cancer Cell106 citations Open access
Semantic Scholar
Mechanisms of sensitivity and resistance to CDK4/CDK6 inhibitors in hormone receptor-positive breast cancer treatment.
Antonino Glaviano, S. Wander, Richard D. Baird, K. C. Yap +17 more
2024Drug resistance updates75 citations Open access
Semantic Scholar
Repression of Transcription by WT1-BASP1 Requires the Myristoylation of BASP1 and the PIP2-Dependent Recruitment of Histone Deacetylase
Eneda Toska, H. Campbell, Jayasha Shandilya, S. Goodfellow +3 more
2012Cell Reports75 citations Open access
Semantic Scholar
Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2)
E. Cocco, F. Carmona, P. Razavi, H. Won +25 more
2018Science Signaling68 citations Open access
Semantic Scholar
PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression
Eneda Toska, P. Castel, S. Chhangawala, A. Arruabarrena-Aristorena +13 more
2019Cell Reports57 citations Open access
Semantic Scholar
UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth
A. Wolfe, Qingwen Zhou, Eneda Toska, Jacqueline Galeas +7 more
2021Proceedings of the National Academy of Sciences of the United States of America48 citations Open access
Semantic Scholar
Presenilin influences glycogen synthase kinase-3 β (GSK-3β) for kinesin-1 and dynein function during axonal transport.
Kunsang Dolma, G. Iacobucci, K. Zheng, Jayasha Shandilya +4 more
2014Human Molecular Genetics46 citations Open access
Semantic Scholar
TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors
E. Cocco, J. E. Lee, S. Kannan, A. Schram +30 more
2020Cancer Discovery45 citations Open access
Semantic Scholar
WT1 and its transcriptional cofactor BASP1 redirect the differentiation pathway of an established blood cell line
S. Goodfellow, Michelle R. Rebello, Eneda Toska, L. Zeef +3 more
2011Biochemical Journal44 citations Open access
Semantic Scholar
Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265P mutations.
P. Mondello, E. Brea, E. de Stanchina, Eneda Toska +8 more
2017JCI Insight42 citations Open access
Semantic Scholar
Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs
H. Osmanbeyoglu, Eneda Toska, Carmen Chan, J. Baselga +1 more
2017Nature Communications35 citations Open access
Semantic Scholar
Genomic alterations in PIK3CA-mutated breast cancer result in mTORC1 activation and limit the sensitivity to PI3Kα inhibitors
Yan-Yan Cai, Guotai Xu, Fan Wu, Flavia Michelini +17 more
2021Cancer Research29 citations Open access
Semantic Scholar
Prohibitin is required for transcriptional repression by the WT1-BASP1 complex
Eneda Toska, Jayasha Shandilya, S. Goodfellow, K. Medler +1 more
2013Oncogene29 citations Open access
Semantic Scholar
WT1 regulates the development of the posterior taste field
Yankun Gao, Eneda Toska, Dane Denmon, S. Roberts +1 more
2014Development25 citations Open access
Semantic Scholar
Cholesterol is required for transcriptional repression by BASP1
Amy E. Loats, S. Carrera, Anna F. Fleming, Abigail R. E. Roberts +5 more
2021Proceedings of the National Academy of Sciences of the United States of America22 citations Open access
Semantic Scholar
Zurletrectinib is a next-generation TRK inhibitor with strong intracranial activity against NTRK fusion-positive tumours with on-target resistance to first-generation agents
Paola Roa, Valentina Foglizzo, Guilherme Harada, M. Repetto +18 more
2024British Journal of Cancer20 citations Open access
Semantic Scholar
WT1 Interacts with MAD2 and Regulates Mitotic Checkpoint Function
Jayasha Shandilya, Eneda Toska, D. Richard, K. Medler +1 more
2014Nature Communications20 citations Open access
Semantic Scholar
Pharmacology in the Era of Targeted Therapies: The Case of PI3K Inhibitors
Eneda Toska, J. Baselga
2016Clinical Cancer Research18 citations Open access
Semantic Scholar
Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer
Ryan Blawski, Bujamin Vokshi, Xinyu Guo, Srushti Kittane +23 more
2024Cell Reports17 citations Open access
Semantic Scholar
Rationale-based therapeutic combinations with PI3K inhibitors in cancer treatment
P. Castel, Eneda Toska, Z. Zumsteg, F. Carmona +3 more
2014Molecular & Cellular Oncology17 citations Open access
Semantic Scholar
Classification of a frameshift/extended and a stop mutation in WT1 as gain-of-function mutations that activate cell cycle genes and promote Wilms tumour cell proliferation
M. Busch, H. Schwindt, A. Brandt, M. Beier +6 more
2014Human Molecular Genetics17 citations Open access
Semantic Scholar
Epigenetic mechanisms of cancer progression and therapy resistance in estrogen-receptor (ER+) breast cancer.
Eneda Toska
2024Biochimica et biophysica acta. Reviews on cancer16 citations Open access
Semantic Scholar
TRI_tool: a web-tool for prediction of protein–protein interactions in human transcriptional regulation
Vladimir Perović, Neven Sumonja, Branislava Gemović, Eneda Toska +2 more
2017Bioinform.16 citations Open access
Semantic Scholar
Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer
S. Olsen, Bryn Anderson, Charles Hatton, Zheng-Tao Chu +9 more
2025Cell Reports Medicine12 citations Open access
Semantic Scholar
TFE3 fusion oncoprotein condensates drive transcriptional reprogramming and cancer progression in translocation renal cell carcinoma
C. So, Y. Lee, Bujamin Vokshi, Wanlu Chen +11 more
2025Cell Reports11 citations Open access
Semantic Scholar
Interpretable deep learning for chromatin-informed inference of transcriptional programs driven by somatic alterations across cancers
Yifeng Tao, Xiaojun Ma, Georgios I. Laliotis, A. G. Zuniga +5 more
2021bioRxiv10 citations Open access
Semantic Scholar
University of Dundee PDK 1-SGK 1 signaling sustains AKT-independent mTORC 1 activation and confers resistance to PI 3 K inhibition
P. Castel, H. Ellis, R. Bago, Eneda Toska +10 more
201610 citations
Semantic Scholar
Inhibition of NR2F2 restores hormone therapy response to endocrine refractory breast cancers
Yan-Yan Cai, Pei-Hua Zhao, Fan Wu, Hui-Yong Zhao +16 more
2025Science Translational Medicine9 citations Open access
Semantic Scholar
Mutant ARID1A: igniting cancer immunotherapy.
Bujamin Vokshi, Eneda Toska
2024Trends in immunology9 citations
Semantic Scholar
ERK hyperactivation serves as a unified mechanism of escape in intrinsic and acquired CDK4/6 inhibitor resistance in acral lentiginous melanoma
K. Jagirdar, Marie E Portuallo, Mei-Han Wei, Matthew Wilhide +20 more
2023Oncogene8 citations Open access
Semantic Scholar
Androgen receptor drives polyamine synthesis creating a vulnerability for prostate cancer
Rajendra Kumar, Sheila Jonnatan, David E. Sanin, Varsha Vakkala +23 more
2025Cancer Research7 citations Open access
Semantic Scholar
A Unique FOXA1-Associated Chromatin State Dictates Therapeutic Resistance in Lobular Breast Cancer
Ryan Blawski, Eneda Toska
2022Cancer Research7 citations Open access
Semantic Scholar
Epigenetic Mechanisms Influencing Therapeutic Response in Breast Cancer
A. Arruabarrena-Aristorena, Eneda Toska
2022Frontiers in Oncology7 citations Open access
Semantic Scholar
Chromatin regulation at the intersection of estrogen receptor and PI3K pathways in breast cancer
P. Castel, Eneda Toska
2019Molecular & Cellular Oncology7 citations Open access
Semantic Scholar
The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation
Erik M. Ladewig, Flavia Michelini, K. Jhaveri, P. Castel +16 more
2022Cancer Research6 citations Open access
Semantic Scholar
Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265P mutations.
P. Mondello, E. Brea, E. de Stanchina, Eneda Toska +8 more
2018JCI Insight6 citations Open access
Semantic Scholar
Neratinib induces estrogen receptor function and sensitizes HER2-mutant breast cancer to anti-endocrine therapy
M. Scaltriti, F. Carmona, Eneda Toska, E. Cocco +7 more
20166 citations
Semantic Scholar
ERK Hyperactivation Serves as a Unified Mechanism of Escape in Intrinsic and Acquired CDK4/6 Inhibitor Resistance in Acral Lentiginous Melanoma
Vito W. Rebecca, K. Jagirdar, Marie E Portuallo, Mei-Han Wei +19 more
2023Research Square5 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

M. Scaltriti×16
Invite
M. Scaltriti — researcher profile on SciRah
J. Baselga×15
Invite
J. Baselga — researcher profile on SciRah
P. Castel×10
Invite
P. Castel — researcher profile on SciRah
P. Razavi×10
Invite
P. Razavi — researcher profile on SciRah

S. Chandarlapaty

×8

Invite

S. Chandarlapaty — researcher profile on SciRah

Invite

E. Cocco — researcher profile on SciRah

E. de Stanchina×8

Invite

E. de Stanchina — researcher profile on SciRah

Invite

S. Roberts — researcher profile on SciRah

Invite

Carmen Chan — researcher profile on SciRah

Invite

Yan-Yan Cai — researcher profile on SciRah

Invite

K. Medler — researcher profile on SciRah

Invite

M. Dickler — researcher profile on SciRah