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L. Nielsen · SciRah

Researcher profile · Semantic Scholar

L. Nielsen

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L. Nielsen — researcher profile on SciRah

h-index: 49
Works: 170
Citations: 8,994

Most-cited papers

Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects
S. Larsen, J. Nielsen, C. N. Hansen, L. Nielsen +7 more
2012Journal of Physiology1,161 citations Open access
Semantic Scholar
Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M
Christina Christoffersen, Hideru Obinata, Sunil B. Kumaraswamy, S. Galvani +7 more
2011Proceedings of the National Academy of Sciences of the United States of America613 citations Open access
Semantic Scholar
Severely impaired von Willebrand factor-dependent platelet aggregation in patients with a continuous-flow left ventricular assist device (HeartMate II).
J. Klovaite, F. Gustafsson, S. Mortensen, K. Sander +1 more
2009Journal of the American College of Cardiology274 citations Open access
Semantic Scholar
Familial Hypercholesterolemia and Atherosclerosis in Cloned Minipigs Created by DNA Transposition of a Human PCSK9 Gain-of-Function Mutant
R. Al-Mashhadi, C. B. Sørensen, P. M. Kragh, Christina Christoffersen +17 more
2013Science Translational Medicine205 citations
Semantic Scholar
Simvastatin effects on skeletal muscle: relation to decreased mitochondrial function and glucose intolerance.
S. Larsen, N. Stride, Martin Hey‐Mogensen, C. N. Hansen +5 more
2013Journal of the American College of Cardiology176 citations Open access
Semantic Scholar
The Bipolar Illness Onset study: research protocol for the BIO cohort study
L. Kessing, K. Munkholm, M. Faurholt-Jepsen, K. Miskowiak +15 more
2017BMJ Open155 citations Open access
Semantic Scholar
Hypoxia-Inducible Factor-1&agr; Expression in Macrophages Promotes Development of Atherosclerosis
Annemarie Aarup, T. X. Pedersen, N. Junker, Christina Christoffersen +4 more
2016Arteriosclerosis, Thrombosis and Vascular Biology138 citations Open access
Semantic Scholar
Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL.
S. Elsøe, J. Ahnström, Christina Christoffersen, A. Hoofnagle +6 more
2011Atherosclerosis122 citations
Semantic Scholar
Impaired endothelial barrier function in apolipoprotein M‐deficient mice is dependent on sphingosine‐1‐phosphate receptor 1
Pernille M. Christensen, Catherine H. Liu, Steven L. Swendeman, Hideru Obinata +5 more
2016The FASEB Journal112 citations Open access
Semantic Scholar
Bone marrow-derived and peritoneal macrophages have different inflammatory response to oxLDL and M1/M2 marker expression – implications for atherosclerosis research
L. Bisgaard, C. K. Mogensen, Alexander Rosendahl, Helena Cucak +3 more
2016Scientific Reports108 citations Open access
Semantic Scholar
Apolipoprotein M predicts pre‐β‐HDL formation: studies in type 2 diabetic and nondiabetic subjects
P. Plomgaard, R. Dullaart, R. D. De Vries, A. Groen +2 more
2009Journal of Internal Medicine76 citations
Semantic Scholar
The Signal Peptide Anchors Apolipoprotein M in Plasma Lipoproteins and Prevents Rapid Clearance of Apolipoprotein M from Plasma*
Christina Christoffersen, J. Ahnström, O. Axler, E. Christensen +2 more
2008Journal of Biological Chemistry72 citations Open access
Semantic Scholar
Polybrominated Diphenyl Ethers and Perfluoroalkyl Substances in Serum of Pregnant Women: Levels, Correlations, and Potential Health Implications
K. Vorkamp, F. Nielsen, H. Kyhl, S. Husby +4 more
2014Archives of Environmental Contamination and Toxicology67 citations
Semantic Scholar
HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver.
B. Ding, Catherine H. Liu, Yue Sun, Yutian Chen +9 more
2016JCI Insight64 citations Open access
Semantic Scholar
Altered metabolism of LDL in the arterial wall precedes atherosclerosis regression.
E. Bartels, Christina Christoffersen, M. Lindholm, L. Nielsen
2015Circulation Research64 citations
Semantic Scholar
Sphingosine-1-phosphate reduces ischaemia-reperfusion injury by phosphorylating the gap junction protein Connexin43.
S. Morel, Christina Christoffersen, L. Axelsen, F. Montecucco +10 more
2016Cardiovascular Research63 citations Open access
Semantic Scholar
Decreased expression of natriuretic peptides associated with lipid accumulation in cardiac ventricle of obese mice.
E. Bartels, J. M. Nielsen, L. Bisgaard, J. Goetze +1 more
2010Endocrinology62 citations Open access
Semantic Scholar
A Human ApoB100 Transgenic Mouse expresses human ApoB100 in the RPE and develops features of early AMD
M. Fujihara, E. Bartels, L. Nielsen, J. Handa
2009Experimental Eye Research62 citations Open access
Semantic Scholar
Apolipoprotein M: bridging HDL and endothelial function
Christina Christoffersen, L. Nielsen
2013Current Opinion in Lipidology59 citations
Semantic Scholar
Deficiency of the GPR39 receptor is associated with obesity and altered adipocyte metabolism
P. S. Petersen, Chunyu Jin, A. N. Madsen, Maria Rasmussen +5 more
2011The FASEB Journal52 citations
Semantic Scholar
Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis
L. Axelsen, K. Calloe, T. Braunstein, Mads Riemann +10 more
2015Cardiovascular Diabetology51 citations Open access
Semantic Scholar
Apolipoprotein M in lipid metabolism and cardiometabolic diseases
A. Borup, Pernille M. Christensen, L. Nielsen, Christina Christoffersen
2015Current Opinion in Lipidology50 citations
Semantic Scholar
ApoM: gene regulation and effects on HDL metabolism.
L. Nielsen, Christina Christoffersen, J. Ahnström, B. Dahlbäck
2009Trends in endocrinology and metabolism49 citations
Semantic Scholar
The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity.
Christina Christoffersen, C. Federspiel, A. Borup, Pernille M. Christensen +7 more
2018Cell Reports48 citations Open access
Semantic Scholar
Expression of Apolipoprotein B in the Kidney Attenuates Renal Lipid Accumulation*
M. Krzystanek, T. X. Pedersen, E. Bartels, Jacob Kjæhr +2 more
2010Journal of Biological Chemistry48 citations Open access
Semantic Scholar
Opposing Effects of Apolipoprotein M on Catabolism of Apolipoprotein B–Containing Lipoproteins and Atherosclerosis
Christina Christoffersen, T. X. Pedersen, P. Gordts, A. Roebroek +2 more
2010Circulation Research46 citations Open access
Semantic Scholar
Aging suppresses sphingosine-1-phosphate (S1P) chaperone ApoM in circulation resulting in maladaptive organ repair
B. Ding, Da-Wei Yang, S. Swendeman, Christina Christoffersen +5 more
2020Developmental Cell43 citations Open access
Semantic Scholar
Liraglutide Reduces Both Atherosclerosis and Kidney Inflammation in Moderately Uremic LDLr-/- Mice
L. Bisgaard, M. H. Bosteen, L. N. Fink, C. M. Sørensen +6 more
2016PLoS ONE43 citations Open access
Semantic Scholar
The Apolipoprotein M–Sphingosine-1-Phosphate Axis: Biological Relevance in Lipoprotein Metabolism, Lipid Disorders and Atherosclerosis
Bas W. C. Arkensteijn, J. Berbée, P. Rensen, L. Nielsen +1 more
2013International Journal of Molecular Sciences42 citations Open access
Semantic Scholar
The plasma concentration of HDL-associated apoM is influenced by LDL receptor-mediated clearance of apoB-containing particles
Christina Christoffersen, M. Benn, Pernille M. Christensen, P. Gordts +5 more
2012Journal of Lipid Research41 citations Open access
Semantic Scholar
Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels
C. L. Haase, R. Frikke-Schmidt, B. Nordestgaard, A. Kateifides +8 more
2011Journal of Internal Medicine40 citations Open access
Semantic Scholar
Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes
Pernille M. Christensen, M. H. Bosteen, S. Hajny, L. Nielsen +1 more
2017Scientific Reports39 citations Open access
Semantic Scholar
Hypoxia Changes the Expression of the Epidermal Growth Factor (EGF) System in Human Hearts and Cultured Cardiomyocytes
Mathias Munk, A. Memon, J. Goetze, L. Nielsen +2 more
2012PLoS ONE39 citations Open access
Semantic Scholar
Apolipoprotein M promotes mobilization of cellular cholesterol in vivo.
S. Elsøe, Christina Christoffersen, J. Luchoomun, S. Turner +1 more
2013Biochimica et Biophysica Acta38 citations
Semantic Scholar
Apolipoprotein M affecting lipid metabolism or just catching a ride with lipoproteins in the circulation?
B. Dahlbäck, L. Nielsen
2009Cellular and Molecular Life Sciences36 citations Open access
Semantic Scholar
Cardiac Expression of Microsomal Triglyceride Transfer Protein Is Increased in Obesity and Serves to Attenuate Cardiac Triglyceride Accumulation
E. Bartels, J. M. Nielsen, L. Hellgren, T. Ploug +1 more
2009PLoS ONE36 citations Open access
Semantic Scholar
Plasma apolipoprotein M is reduced in metabolic syndrome but does not predict intima media thickness.
R. Dullaart, P. Plomgaard, R. D. De Vries, B. Dahlbäck +1 more
2009Clinica chimica acta; international journal of clinical chemistry34 citations
Semantic Scholar
Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice
P. Gordts, A. Bartelt, S. K. Nilsson, W. Annaert +4 more
2012PLoS ONE32 citations Open access
Semantic Scholar
Apolipoprotein M - a new biomarker in sepsis
Christina Christoffersen, L. Nielsen
2012Critical Care30 citations Open access
Semantic Scholar
Association of apolipoprotein M with high-density lipoprotein kinetics in overweight-obese men.
E. Ooi, G. Watts, Dick C. Chan, L. Nielsen +3 more
2010Atherosclerosis30 citations
Semantic Scholar
ACE inhibition attenuates uremia-induced aortic valve thickening in a novel mouse model
M. Simolin, T. X. Pedersen, S. Bro, M. Mäyränpää +3 more
2009BMC Cardiovascular Disorders30 citations Open access
Semantic Scholar
Treatment with a human recombinant monoclonal IgG antibody against oxidized LDL in atherosclerosis-prone pigs reduces cathepsin S in coronary lesions.
C. B. Poulsen, A. Al-Mashhadi, K. von Wachenfeldt, J. Bentzon +15 more
2016International Journal of Cardiology27 citations
Semantic Scholar
Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice
M. Madsen, P. Hansen, L. Nielsen, K. Hartvigsen +4 more
2016BMC Dermatology26 citations Open access
Semantic Scholar
Apolipoprotein M in patients with chronic kidney disease.
Ida Sørensen, Marianne Bertelsen, E. Freese, K. Lindhard +5 more
2018Atherosclerosis25 citations
Semantic Scholar
Effects of apolipoprotein M in uremic atherosclerosis.
M. H. Bosteen, Eva Martha Madsen Svarrer, L. Bisgaard, T. Martinussen +4 more
2017Atherosclerosis23 citations
Semantic Scholar
Effect of treatment with human apolipoprotein A-I on atherosclerosis in uremic apolipoprotein-E deficient mice.
T. X. Pedersen, S. Bro, M. H. Andersen, M. Etzerodt +3 more
2009Atherosclerosis23 citations
Semantic Scholar
Exercise and weight loss effects on cardiovascular risk factors in overweight men.
M. Rosenkilde, L. Rygaard, P. Nordby, L. Nielsen +1 more
2018Journal of applied physiology21 citations Open access
Semantic Scholar
Allele-specific regulation of MTTP expression influences the risk of ischemic heart disease[S]
Anna Aminoff, H. Ledmyr, Petra Thulin, K. Lundell +16 more
2010Journal of Lipid Research21 citations Open access
Semantic Scholar
Osteopontin deficiency dampens the pro-atherogenic effect of uraemia.
T. X. Pedersen, M. Madsen, N. Junker, Christina Christoffersen +4 more
2013Cardiovascular Research20 citations Open access
Semantic Scholar
Endothelial function after 10 days of bed rest in individuals at risk for type 2 diabetes and cardiovascular disease
M. P. Sonne, L. Højbjerre, A. Alibegovic, L. Nielsen +3 more
2011Experimental Physiology17 citations Open access
Semantic Scholar

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