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T. Hurley · SciRah

Researcher profile · Semantic Scholar

T. Hurley

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T. Hurley — researcher profile on SciRah

h-index: 11
Works: 22
Citations: 512

Most-cited papers

AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism[S]
Stephen L. Pinkosky, S. Filippov, R. Srivastava, J. Hanselman +10 more
2013Journal of Lipid Research139 citations Open access
Semantic Scholar
Novel antitumor agents CI-920, PD 113,270 and PD 113,271. II. Isolation and characterization.
S. Stampwala, R. H. Bunge, T. Hurley, N. E. Willmer +4 more
1983Journal of antibiotics (Tokyo. 1968)108 citations Open access
Semantic Scholar
ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK
S. Filippov, Stephen L. Pinkosky, Richard J. Lister, Catherine Pawloski +7 more
2013Journal of Lipid Research80 citations Open access
Semantic Scholar
Orally active water-soluble N,O-acyl transfer products of a beta,gamma-bishydroxyl amide containing renin inhibitor.
T. Hurley, C. E. Colson, G. Hicks, Michael J. Ryan
1993Journal of Medicinal Chemistry28 citations
Semantic Scholar
PD 124,895 and PD 124,966, two new antitumor antibiotics.
T. Hurley, R. H. Bunge, N. E. Willmer, G. Hokanson +1 more
1986Journal of antibiotics (Tokyo. 1968)27 citations Open access
Semantic Scholar
Synthesis and characterization of pregabalin lactose conjugate degradation products.
M. Lovdahl, T. Hurley, B. Tobias, S. Priebe
2002Journal of Pharmaceutical and Biomedical Analysis23 citations
Semantic Scholar
Renin inhibitors containing esters at the P2-position. Oral activity in a derivative of methyl aminomalonate.
J. Repine, R. Himmelsbach, J. C. Hodges, J. S. Kaltenbronn +6 more
1991Journal of Medicinal Chemistry17 citations Open access
Semantic Scholar
Isolation and Structure of a New Antibiotic Related to Rubiflavin A
H. Nadig, U. Séquin, R. H. Bunge, T. Hurley +2 more
198515 citations
Semantic Scholar
PD 113,618 and PD 118,309, new pactamycin analogs.
T. Hurley, T. A. Smitka, J. Wilton, R. H. Bunge +2 more
1986Journal of antibiotics (Tokyo. 1968)14 citations Open access
Semantic Scholar
Norethindrone acetate (NA) and ethinyl estradiol (EE) related oxidative transformation products in stability samples of formulated drug product: synthesis of authentic references.
I. Ekhato, T. Hurley, M. Lovdahl, T. J. Revitte +4 more
2002Steroids12 citations
Semantic Scholar
Photodecomposition of CI-981, an HMG-CoA reductase inhibitor
T. Hurley, C. E. Colson, S. Clipper, S. Uhlendorf +1 more
199311 citations
Semantic Scholar
Effect of Sub‐2‐Micron Particle Size on Peak Efficiency, Capacity, and Resolution in Preparative Liquid Chromatography
Douglas Durham, T. Hurley
200710 citations
Semantic Scholar
PD 114,759 and PD 115,028, novel antitumor antibiotics with phenomenal potency. I. Isolation and characterization.
R. H. Bunge, T. Hurley, Tim A. Smitka, N. E. Willmer +3 more
1984Journal of antibiotics (Tokyo. 1968)10 citations Open access
Semantic Scholar
Improved production of pentostatin and identification of fermentation cometabolites.
H. D. Hollis Showalter, R. H. Bunge, James C. French, T. Hurley +4 more
1992Journal of antibiotics (Tokyo. 1968)9 citations Open access
Semantic Scholar
Inhibitors of acyl-CoA: Cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. 13. Design, synthesis and biological evaluation of tetrazole anilides as potent inhibitors of ACAT in vitro and hypocholesterolemic agents in vivo
P. M. O'Brien, D. Sliskovic, A. Bernabei, T. Hurley +4 more
19955 citations
Semantic Scholar
Discovery of analogues of non-β oxidizable long-chain dicarboxylic fatty acids as dual inhibitors of fatty acids and cholesterol synthesis: Efficacy of lead compound in hyperlipidemic hamsters reveals novel mechanism.
R. Srivastava, T. Hurley, D. Oniciu, K. Adeli +1 more
2021NMCD. Nutrition Metabolism and Cardiovascular Diseases3 citations
Semantic Scholar
Abstract 292: ETC-1002 Reduces Body Weight Gain and Hepatic Triglyceride Content and Improves Glycemic Control in a Mouse Model of Diet-Induced Obesity
J. Hanselman, R. Srivastava, T. Hurley, S. Filippov +6 more
2012Arteriosclerosis, Thrombosis and Vascular Biology1 citations
Semantic Scholar
Corrigendum to "Discovery of analogues of non-β oxidizable long-chain dicarboxylic fatty acids as dual inhibitors of fatty acids and cholesterol synthesis: Efficacy of lead compound in hyperlipidemic hamsters reveals novel mechanism" [Nutr Metabol Cardiovasc Dis 31 (2021) 2490-2703].
R. Srivastava, T. Hurley, D. Oniciu, K. Adeli +1 more
2021NMCD. Nutrition Metabolism and Cardiovascular Diseases0 citations Open access
Semantic Scholar
Abstract 465: ETC-1002, a Novel Dicarboxylic Fatty Acid Analog, Inhibits Inflammatory Response in Primary Human Monocyte-Derived Macrophages as Well as in Adipose Tissue of Insulin-Resistant Mice via AMPK-Dependent Mechanisms
S. Filippov, Richard J. Lister, Stephen L. Pinkosky, C. D. Bradshaw +5 more
2012Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar
Photodecomposition of CI-981, an HMG-CoA Reductase Inhibitor.
T. Hurley, C. E. Colson, S. Clipper, S. Uhlendorf +1 more
19930 citations
Semantic Scholar
Sulfur-containing antibiotic and cytotoxic compounds, designated Cl-1577d and C-1577E, processes for their preparation, and to pharmaceutical compositions containing the compounds
A. J. Brankiewicz, R. H. Bunge, J. C. French, G. Hokanson +2 more
19850 citations
Semantic Scholar
Sulfur-containing antibiotic compounds having antitumor activity, designated CL-1577A and CL-1577B, process for their preparation, and to pharmaceutical compositions containing the compounds
R. H. Bunge, J. C. French, T. Hurley, T. A. Smitka +1 more
19840 citations
Semantic Scholar

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