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Chris Towne · SciRah

Researcher profile · Semantic Scholar

Chris Towne

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Chris Towne — researcher profile on SciRah

h-index: 16
Works: 28
Citations: 1,640

Most-cited papers

Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration
Artem Kaplan, Krista J. Spiller, Chris Towne, K. Kanning +5 more
2014Neuron299 citations Open access
Semantic Scholar
Virally mediated optogenetic excitation and inhibition of pain in freely moving non-transgenic mice
S. M. Iyer, K. L. Montgomery, Chris Towne, S. Lee +3 more
2014Nature Biotechnology217 citations Open access
Semantic Scholar
Optogenetic Control of Targeted Peripheral Axons in Freely Moving Animals
Chris Towne, K. L. Montgomery, S. M. Iyer, K. Deisseroth +1 more
2013PLoS ONE157 citations Open access
Semantic Scholar
Systemic AAV6 delivery mediating RNA interference against SOD1: neuromuscular transduction does not alter disease progression in fALS mice.
Chris Towne, C. Raoul, B. Schneider, P. Aebischer
2008Molecular Therapy134 citations Open access
Semantic Scholar
Efficient transduction of non-human primate motor neurons after intramuscular delivery of recombinant AAV serotype 6
Chris Towne, B. Schneider, D. Kieran, D. Redmond +1 more
2010Gene Therapy129 citations Open access
Semantic Scholar
Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain.
C. Laedermann, M. Cachemaille, Guylène Kirschmann, M. Pertin +8 more
2013Journal of Clinical Investigation122 citations Open access
Semantic Scholar
Molecular Pain
Open Access, Chris Towne, M. Pertin, A. Beggah +2 more
201791 citations
Semantic Scholar
Structural and functional evidence for the interaction of insulin-like growth factors (IGFs) and IGF binding proteins with vitronectin.
J. Kricker, Chris Towne, S. Firth, A. Herington +1 more
2003Endocrinology90 citations Open access
Semantic Scholar
Neuroprotection by gene therapy targeting mutant SOD1 in individual pools of motor neurons does not translate into therapeutic benefit in fALS mice.
Chris Towne, V. Setola, B. Schneider, P. Aebischer
2011Molecular Therapy69 citations Open access
Semantic Scholar
SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice
Elisabeth Dirren, J. Aebischer, C. Rochat, Chris Towne +2 more
2015Annals of Clinical and Translational Neurology65 citations Open access
Semantic Scholar
Intracerebroventricular Injection of Adeno-Associated Virus 6 and 9 Vectors for Cell Type–Specific Transgene Expression in the Spinal Cord
Elisabeth Dirren, Chris Towne, V. Setola, D. Redmond +2 more
2014Human Gene Therapy58 citations Open access
Semantic Scholar
Migration of breast cancer cells: understanding the roles of volume exclusion and cell-to-cell adhesion.
M. Simpson, Chris Towne, D. L. Sean McElwain, Z. Upton
2010Physical review. E, Statistical, nonlinear, and soft matter physics56 citations Open access
Semantic Scholar
OPTICAL INHIBITION OF MOTOR NERVE AND MUSCLE ACTIVITY IN VIVO
Holly Liske, Chris Towne, P. Anikeeva, Sheng-Li Zhao +3 more
2013Muscle and Nerve38 citations Open access
Semantic Scholar
Insulin-like growth factor-II bound to vitronectin enhances MCF-7 breast cancer cell migration.
A. Noble, Chris Towne, L. Chopin, D. Leavesley +1 more
2003Endocrinology36 citations Open access
Semantic Scholar
Regulation of Episomal Gene Expression by KRAB/KAP1-Mediated Histone Modifications
Isabelle Barde, E. Laurenti, Sonia Verp, A. Groner +5 more
2009Journal of Virology31 citations Open access
Semantic Scholar
Overview on Research and Clinical Applications of Optogenetics
Chris Towne, Kimberly R. Thompson
2016Current Protocols in Pharmacology28 citations
Semantic Scholar
Lentiviral and adeno-associated vector-based therapy for motor neuron disease through RNAi.
Chris Towne, P. Aebischer
2009Methods in molecular biology15 citations Open access
Semantic Scholar
A Hitchhiker’s Guide to the Selection of Viral Vectors for Optogenetic Studies
Kimberly R. Thompson, Chris Towne
20183 citations
Semantic Scholar
Recombinant adeno-associated virus serotype 6 (rAAV2/6)-mediated gene transfer to nociceptive neurons through different routes of delivery
Chris Towne, M. Pertin, A. Beggah, P. Aebischer +1 more
2009Molecular Pain2 citations Open access
Semantic Scholar
186. Translating an Optogenetic Gene Therapy Approach for Treatment of Neuropathic Pain in Humans
Chris Towne, J. Aguado, Annie Arguello, C. Discenza +4 more
20161 citations Open access
Semantic Scholar
Adeno-Associated Virus-Mediated Gene Delivery for the Treatment of Amyotrophic Lateral Sclerosis and other Motor Neuron Disorders
Chris Towne
20101 citations
Semantic Scholar
Sixth Annual
Mount David Summit, Chris Towne, Jacob McChesney
20071 citations
Semantic Scholar
Compound Muscle Activated Potential (CMAP) recordings from the triceps surae
Chris Towne
20160 citations
Semantic Scholar
Nedd4-2 ubiquitin ligase: a contributor to experimental neuropathic pain?
M. Cachemaille, C. Laedermann, M. Pertin, Chris Towne +3 more
20100 citations
Semantic Scholar
Characterization of Nedd4-2 ubiquitin ligase expression in experimental neuropathic pain
M. Cachemaille, C. Laedermann, M. Pertin, Chris Towne +2 more
20090 citations
Semantic Scholar
229 EFFICACY AND SPECIFICITY OF RECOMBINANT ADENO‐ASSOCIATED VIRUS SEROTYPE 6 MEDIATED GENE TRANSFER TO DRG NEURONS THROUGH DIFFERENT ROUTES OF DELIVERY
M. Pertin, Chris Towne, A. Beggah, P. Aebischer +1 more
20090 citations
Semantic Scholar
Feasibility of gene therapy for the treatment of neuropathic pain: downregulation of GTP cyclohydrolase 1 expression via RNA interference
S. Jean, Chris Towne, P. Aebischer, I. Decosterd
20080 citations
Semantic Scholar
Neuropathic pain: Gene therapy as a tool to transduce nociceptors
M. Pertin, Chris Towne, T. Berta, A. Beggah +2 more
20080 citations
Semantic Scholar

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