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Linda Wernevik · SciRah

Researcher profile · Semantic Scholar

Linda Wernevik

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Linda Wernevik — researcher profile on SciRah

h-index: 8
Works: 13
Citations: 285

Most-cited papers

An oral antisense oligonucleotide for PCSK9 inhibition
Peter Gennemark, Katrin Walter, N. Clemmensen, D. Rekić +24 more
2021Science Translational Medicine109 citations
Semantic Scholar
AZD2693, a PNPLA3 antisense oligonucleotide, for the treatment of MASH in 148M homozygous participants: two randomized phase I trials.
J. Armisen, Mitra Rauschecker, Janeli Sarv, Mathias Liljeblad +22 more
2025Journal of Hepatology63 citations Open access
Semantic Scholar
Safety, Tolerability, and Pharmacokinetics of the Mineralocorticoid Receptor Modulator AZD9977 in Healthy Men: A Phase I Multiple Ascending Dose Study
A. Whittaker, A. Kragh, Judith Hartleib-Geschwindner, M. Albayaty +8 more
2019Clinical and Translational Science27 citations Open access
Semantic Scholar
Clinical safety, tolerability, pharmacokinetics and effects on urinary electrolyte excretion of AZD9977, a novel, selective mineralocorticoid receptor modulator
F. Erlandsson, M. Albayaty, Ligia Chialda, H. Ericsson +7 more
2018British Journal of Clinical Pharmacology25 citations Open access
Semantic Scholar
ETESIAN: A PHASE 2B STUDY OF THE EFFICACY, SAFETY AND TOLERABILITY OF AZD8233, A PCSK9-TARGETED ANTISENSE OLIGONUCLEOTIDE, IN PATIENTS WITH DYSLIPIDEMIA
M. Koren, A. Hofherr, Jennifer Schumi, D. Rekić +6 more
2022Journal of the American College of Cardiology24 citations Open access
Semantic Scholar
AZD8233 antisense oligonucleotide targeting PCSK9 does not prolong QT interval
D. Rekić, Ivan Azarov, Jane Knöchel, V. Sokolov +7 more
2022British Journal of Clinical Pharmacology16 citations Open access
Semantic Scholar
Effect of AZD9977 and spironolactone on serum potassium in heart failure with preserved or mildly reduced ejection fraction, and renal impairment: A randomized trial
I. Squire, A. Gabrielsen, P. Greasley, Linda Wernevik +8 more
2022Clinical and Translational Science10 citations Open access
Semantic Scholar
A case‐study of model‐informed drug development of a novel PCSK9 anti sense oligonucleotide. Part 1: First time in man to phase II
Jane Knöchel, C. Nilsson, B. Carlsson, Linda Wernevik +7 more
2022CPT: Pharmacometrics & Systems Pharmacology8 citations Open access
Semantic Scholar
Population pharmacokinetics of a novel PCSK9 antisense oligonucleotide
Oskar Clewe, D. Rekić, A. Quartino, Björn Carlsson +6 more
2024British Journal of Clinical Pharmacology5 citations Open access
Semantic Scholar
Abstract 13913: Single Dose Safety, Pharmacokinetics, and Pharmacodynamics of a Potent PCSK9 Synthesis Inhibitor, AZD8233, in Subjects With Elevated Ldl Cholesterol
Catarina Nilsson, Brett P. Monia, Kristina Ryden-Bergsten, D. Rekić +13 more
2020Circulation1 citations
Semantic Scholar
LBP-031 AZD2693, a potent PNPLA3 antisense oligonucleotide, decreases hepatic PNPLA3 mRNA and liver fat content in participants with presumed MASH and homozygous for the PNPLA3148M risk allele
J. Armisen, Mitra Rauschecker, Janeli Sarv, Mathias Liljeblad +18 more
2024Journal of Hepatology0 citations
Semantic Scholar
Patatin-like phospholipase domain-containing 3 (PNPLA3) risk allele increases rate of progression to end-stage liver disease outcomes and decreases survival rate over time irrespective of degree of fibrosis
J. Armisén, J. Blau, N. Fernando, Monika Hun +6 more
2023Journal of Hepatology0 citations
Semantic Scholar
P5713Clinical pharmacology of AZD9977, a novel, selective mineralocorticoid receptor (MR) modulator without K+-sparing properties
A. Whittaker, A. Kragh, Judith Hartleib-Geschwindner, Anna Backlund +7 more
2019European Heart Journal0 citations
Semantic Scholar

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Jane Knöchel×8
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Jane Knöchel — researcher profile on SciRah
D. Rekić×6
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