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A. Breier · SciRah

Researcher profile · Semantic Scholar

A. Breier

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A. Breier — researcher profile on SciRah

h-index: 25
Works: 132
Citations: 2,242

Most-cited papers

Detection of the Mitochondrial Membrane Potential by the Cationic Dye JC-1 in L1210 Cells with Massive Overexpression of the Plasma Membrane ABCB1 Drug Transporter
Katarína Elefantová, B. Lakatoš, J. Kubíčková, Z. Sulová +1 more
2018International Journal of Molecular Sciences199 citations Open access
Semantic Scholar
New insight into p-glycoprotein as a drug target.
A. Breier, L. Gibalová, M. Šereš, M. Barančı́k +1 more
2012Anti-Cancer Agents in Medicinal Chemistry158 citations
Semantic Scholar
SB203580, a specific inhibitor of p38-MAPK pathway, is a new reversal agent of P-glycoprotein-mediated multidrug resistance.
M. Barančı́k, V. Boháčová, J. Kvačkajová, S. Hudecova +2 more
2001European Journal of Pharmaceutical Sciences141 citations
Semantic Scholar
P-glycoprotein--implications of metabolism of neoplastic cells and cancer therapy.
A. Breier, M. Barančı́k, Z. Sulová, B. Uhrík
2005Current Cancer Drug Targets123 citations
Semantic Scholar
LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance.
M. Barančı́k, V. Boháčová, J. Sedlák, Z. Sulová +1 more
2006European Journal of Pharmaceutical Sciences82 citations
Semantic Scholar
H2S and HS− donor NaHS releases nitric oxide from nitrosothiols, metal nitrosyl complex, brain homogenate and murine L1210 leukaemia cells
K. Ondrias, A. Staško, S. Cacanyiova, Z. Sulová +5 more
2008Pflügers Archiv: European Journal of Physiology79 citations
Semantic Scholar
P-glycoprotein depresses cisplatin sensitivity in L1210 cells by inhibiting cisplatin-induced caspase-3 activation.
L. Gibalová, M. Šereš, A. Rusnák, P. Ditte +6 more
2012Toxicology in Vitro62 citations
Semantic Scholar
Adaptation of mouse leukemia cells L1210 to vincristine. Evidence for expression of P-glycoprotein.
Lenka Poleková, Miroslav Barancik, T. Mrázová, R. Pirker +3 more
1992Neoplasma (Bratislava)50 citations
Semantic Scholar
Does any relationship exist between P-glycoprotein-mediated multidrug resistance and intracellular calcium homeostasis.
Z. Sulová, M. Šereš, M. Barančı́k, L. Gibalová +3 more
2009General Physiology and Biophysics48 citations
Semantic Scholar
The Roles of microRNAs in Cancer Multidrug Resistance
L. Pavlikova, M. Šereš, A. Breier, Z. Sulová
2022Cancers47 citations Open access
Semantic Scholar
Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors
Milan Hano, L. Tomasova, M. Šereš, L. Pavlikova +2 more
2018Molecules46 citations Open access
Semantic Scholar
Acute treatment with polyphenol quercetin improves postischemic recovery of isolated perfused rat hearts after global ischemia.
M. Barteková, S. Čarnická, D. Pancza, Mária Ondrejcáková +2 more
2010Canadian Journal of Physiology and Pharmacology44 citations
Semantic Scholar
Inhibitory effect of DIDS, NPPB, and phloretin on intracellular chloride channels
L. Malekova, J. Tomaskova, M. Nováková, P. Štefánik +6 more
2007Pflügers Archiv: European Journal of Physiology44 citations
Semantic Scholar
Different mechanisms of drug resistance to hypomethylating agents in the treatment of myelodysplastic syndromes and acute myeloid leukemia.
K. Simonicova, L. Janotka, H. Kavcová, Z. Sulová +2 more
2022Drug resistance updates43 citations
Semantic Scholar
Na,K-ATPase in the myocardium: molecular principles, functional and clinical aspects.
A. Ziegelhöffer, K. Kjeldsen, H. Bundgaard, A. Breier +2 more
2000General Physiology and Biophysics40 citations
Semantic Scholar
Tunicamycin Depresses P-Glycoprotein Glycosylation Without an Effect on Its Membrane Localization and Drug Efflux Activity in L1210 Cells
M. Šereš, D. Cholujová, Tatiana Bubenčíkova, A. Breier +1 more
2011International Journal of Molecular Sciences38 citations Open access
Semantic Scholar
Reversal effect of specific inhibitors of extracellular-signal regulated protein kinase pathway on P-glycoprotein mediated vincristine resistance of L1210 cells.
J. Kisucka, M. Barančı́k, V. Boháčová, A. Breier
2001General Physiology and Biophysics38 citations
Semantic Scholar
Mechanisms that may be involved in calcium tolerance of the diabetic heart.
A. Ziegelhöffer, T. Ravingerová, J. Styk, J. Šeboková +6 more
199733 citations
Semantic Scholar
Microvascular endothelial cells remodel cultured adult cardiomyocytes and increase their survival.
T. Kubin, H. Ando, D. Scholz, P. Bramlage +8 more
1999American Journal of Physiology. Heart and Circulatory Physiology32 citations
Semantic Scholar
Potentiation of Anticancer Drugs: Effects of Pentoxifylline on Neoplastic Cells
M. Barančı́k, V. Boháčová, L. Gibalová, J. Sedlák +2 more
2011International Journal of Molecular Sciences30 citations Open access
Semantic Scholar
The presence of P-glycoprotein in L1210 cells directly induces down-regulation of cell surface saccharide targets of concanavalin A.
Z. Sulová, P. Ditte, Tatiana Kurucová, E. Polaková +7 more
2010Anticancer Research30 citations
Semantic Scholar
Reversal of P-glycoprotein mediated vincristine resistance of L1210/VCR cells by analogues of pentoxifylline. A QSAR study.
I. Kupsáková, A. Rybár, P. Dočolomanský, Z. Drobnâ +4 more
2004European Journal of Pharmaceutical Sciences29 citations
Semantic Scholar
Functional fluo-3/AM assay on P-glycoprotein transport activity in L1210/VCR cells by confocal microscopy.
Jozef Orlický, Zdena Sulova, Ima Dovinova, R. Fiala +2 more
2004General Physiology and Biophysics27 citations
Semantic Scholar
Expression of P-glycoprotein in L1210 cells is linked with rise in sensitivity to Ca2+.
Z. Sulová, J. Orlický, R. Fiala, I. Dovinová +4 more
2005Biochemical and Biophysical Research Communications - BBRC26 citations
Semantic Scholar
Vincristine-induced overexpression of P-glycoprotein in L1210 cells is associated with remodeling of cell surface saccharides.
Z. Sulová, D. Mislovičová, L. Gibalová, Zuzana Vajcnerová +6 more
2009Journal of Proteome Research25 citations
Semantic Scholar
P-glycoprotein-mediated multidrug resistance phenotype of L1210/VCR cells is associated with decreases of oligo- and/or polysaccharide contents.
R. Fiala, Z. Sulová, A. El-Saggan, B. Uhrík +6 more
2003Biochimica et Biophysica Acta23 citations Open access
Semantic Scholar
Increased activity of sarcolemmal (Na+K+)-ATPase is involved in the late cardioprotective action of 7-oxo-prostacyclin.
A. Džurba, A. Ziegelhoeffer, A. Breier, Norbert Vrbjar +1 more
1991Cardioscience21 citations
Semantic Scholar
Combined treatment of P-gp-positive L1210/VCR cells by verapamil and all-trans retinoic acid induces down-regulation of P-glycoprotein expression and transport activity.
Z. Sulová, D. Macejova, M. Šereš, J. Sedlák +2 more
2008Toxicology in Vitro20 citations
Semantic Scholar
Overexpression of GRP78/BiP in P-Glycoprotein-Positive L1210 Cells is Responsible for Altered Response of Cells to Tunicamycin as a Stressor of the Endoplasmic Reticulum
M. Šereš, L. Pavlikova, V. Boháčová, Tomáš Kyca +4 more
2020Cells19 citations Open access
Semantic Scholar
Acute myeloid leukemia cells MOLM-13 and SKM-1 established for resistance by azacytidine are crossresistant to P-glycoprotein substrates.
L. Messingerová, D. Imrichova, H. Kavcová, Katarína Turáková +2 more
2015Toxicology in Vitro19 citations
Semantic Scholar
Overexpression of P-glycoprotein in L1210/VCR cells is associated with changes in several endoplasmic reticulum proteins that may be partially responsible for the lack of thapsigargin sensitivity.
M. Šereš, E. Polaková, O. Krizanova, S. Hudecova +3 more
2008General Physiology and Biophysics19 citations
Semantic Scholar
L1210 cells cultivated under the selection pressure of doxorubicin or vincristine express common mechanisms of multidrug resistance based on the overexpression of P-glycoprotein.
V. Boháčová, Z. Sulová, I. Dovinová, E. Polaková +4 more
2006Toxicology in Vitro19 citations
Semantic Scholar
Development of Multidrug Resistance in Acute Myeloid Leukemia Is Associated with Alterations of the LPHN1/GAL-9/TIM-3 Signaling Pathway
Zuzana Kocibalova, M. Guzyova, Ivana Borovská, L. Messingerová +3 more
2021Cancers18 citations Open access
Semantic Scholar
Mechanisms that may be involved in calcium tolerance of the diabetic heart
A. Ziegelhöffer, T. Ravingerová, J. Styk, J. Šeboková +6 more
2004Molecular and Cellular Biochemistry18 citations
Semantic Scholar
Optimisation of Recombinant Myrosinase Production in Pichia pastoris
Zuzana Rosenbergová, Kristína Kántorová, M. Šimkovič, A. Breier +1 more
2021International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
Effect of 9-cis retinoic acid and all-trans retinoic acid in combination with verapamil on P-glycoprotein expression in L1210 cells.
A. Breier, J. Stetka, Viera Bohacova, D. Macejova +2 more
2014Neoplasma (Bratislava)17 citations Open access
Semantic Scholar
STATEMENT ON THE VALIDITY OF IN-VITRO TESTS FOR SKIN IRRITATION
T. Hartung, S. Beken, J. van der Valk, A. Breier +1 more
200717 citations
Semantic Scholar
Multidrug resistant P-glycoprotein positive L1210/VCR cells are also cross-resistant to cisplatin via a mechanism distinct from P-glycoprotein-mediated drug efflux activity.
L. Gibalová, J. Sedlák, M. Labudova, M. Barančı́k +3 more
2009General Physiology and Biophysics16 citations Open access
Semantic Scholar
Cell Death Effects Induced by Sulforaphane and Allyl Isothiocyanate on P-Glycoprotein Positive and Negative Variants in L1210 Cells
Szilvia Kontár, D. Imrichova, A. Bertova, Katarina Mackova +3 more
2020Molecules15 citations Open access
Semantic Scholar
The expression of P-gp in leukemia cells is associated with cross-resistance to protein N-glycosylation inhibitor tunicamycin.
L. Pavlikova, M. Šereš, D. Imrichova, Milan Hano +5 more
2016General Physiology and Biophysics15 citations Open access
Semantic Scholar
Detection of Glycomic Alterations Induced by Overexpression of P-Glycoprotein on the Surfaces of L1210 Cells Using Sialic Acid Binding Lectins
Tatiana Bubenčíkova, D. Cholujová, L. Messingerová, D. Mislovičová +3 more
2012International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
Vincristine-induced expression of P-glycoprotein in MOLM-13 and SKM-1 acute myeloid leukemia cell lines is associated with coexpression of nestin transcript.
D. Imrichova, M. Coculova, L. Messingerová, Z. Sulová +1 more
2014General Physiology and Biophysics12 citations Open access
Semantic Scholar
Triorganotin Derivatives Induce Cell Death Effects on L1210 Leukemia Cells at Submicromolar Concentrations Independently of P-glycoprotein Expression
V. Boháčová, M. Šereš, L. Pavlikova, Szilvia Kontár +6 more
2018Molecules11 citations Open access
Semantic Scholar
Sulphoraphane Affinity-Based Chromatography for the Purification of Myrosinase from Lepidium sativum Seeds
Helena Galádová, Zoltán Polozsányi, A. Breier, M. Šimkovič
2022Biomolecules10 citations Open access
Semantic Scholar
The expression of P-glycoprotein in leukemia cells is associated with the upregulated expression of nestin, a class 6 filament protein.
M. Coculova, D. Imrichova, M. Šereš, L. Messingerová +3 more
2016Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis10 citations
Semantic Scholar
Effect of thapsigargin on P-glycoprotein-negative and P-glycoprotein-positive L1210 mouse leukaemia cells.
M. Šereš, P. Ditte, A. Breier, Z. Sulová
2010General Physiology and Biophysics10 citations Open access
Semantic Scholar
Changes in Apoptotic Pathways in MOLM-13 Cell Lines after Induction of Resistance to Hypomethylating Agents
L. Janotka, L. Messingerová, K. Simonicova, H. Kavcová +3 more
2021International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Overexpression of the ABCB1 drug transporter in acute myeloid leukemia cells is associated with downregulation of latrophilin-1.
Zuzana Kocibalova, M. Guzyova, D. Imrichova, Z. Sulová +1 more
2018General Physiology and Biophysics9 citations Open access
Semantic Scholar
L1210 Cells Overexpressing ABCB1 Drug Transporters Are Resistant to Inhibitors of the N- and O-glycosylation of Proteins
L. Pavlikova, M. Šereš, Milan Hano, V. Boháčová +4 more
2017Molecules9 citations Open access
Semantic Scholar
Differential expression of regulatory proteins in L1210/VCR cells with multidrug resistance mediated by P-glycoprotein.
Miroslav Barancik, Viera Bohacova, M. Zbýnovcová, A. Breier
1999General Physiology and Biophysics9 citations
Semantic Scholar

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M. Šereš×17
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M. Barančı́k×11
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