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E. Dow · SciRah

Researcher profile · Semantic Scholar

E. Dow

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E. Dow — researcher profile on SciRah

h-index: 19
Works: 50
Citations: 1,703

Most-cited papers

Gene clustering using self-organizing maps and particle swarm optimization
Xiang Xiao, E. Dow, R. Eberhart, Z. B. Miled +1 more
2003Proceedings International Parallel and Distributed Processing Symposium202 citations
Semantic Scholar
Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 Å resolution
J. Wery, Richard Walter Schevitz, D. Clawson, J. Bobbitt +13 more
1991Nature194 citations
Semantic Scholar
Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases
G. Barturen, S. Babaei, F. Català-Moll, M. Martínez-Bueno +128 more
2020Arthritis & Rheumatology161 citations Open access
Semantic Scholar
Temporal gene expression analysis of monolayer cultured rat hepatocytes.
T. K. Baker, M. Carfagna, Hong Gao, E. Dow +3 more
2001Chemical Research in Toxicology159 citations Open access
Semantic Scholar
Discovery of sequence motifs related to coexpression of genes using evolutionary computation.
G. Fogel, D. Weekes, G. Varga, E. Dow +3 more
2004Nucleic Acids Research114 citations Open access
Semantic Scholar
Molecular profile of catabolic versus anabolic treatment regimens of parathyroid hormone (PTH) in rat bone: An analysis by DNA microarray
Jude E. Onyia, L. M. Helvering, L. Gelbert, T. Wei +16 more
2005Journal of Cellular Biochemistry100 citations
Semantic Scholar
The use of neural networks for variable selection in QSAR
J. Wikel, E. Dow
199383 citations
Semantic Scholar
Assessment of Diet‐induced Obese Rats as an Obesity Model by Comparative Functional Genomics
Shu-Yu D. Li, Hong-yan Zhang, Charlie C. Hu, F. Lawrence +7 more
2008Obesity75 citations Open access
Semantic Scholar
Changes in Osteoblast, Chondrocyte, and Adipocyte Lineages Mediate the Bone Anabolic Actions of PTH and Small Molecule GSK‐3 Inhibitor
N. Kulkarni, T. Wei, Amaresh Kumar, E. Dow +12 more
2007Journal of Cellular Biochemistry68 citations
Semantic Scholar
IL-17 induces inflammation-associated gene products in blood monocytes, and treatment with ixekizumab reduces their expression in psoriasis patient blood.
Claire Q. F. Wang, M. Suárez-Fariñas, K. Nograles, C. A. Mimoso +5 more
2014Journal of Investigative Dermatology61 citations Open access
Semantic Scholar
Baricitinib-associated changes in global gene expression during a 24-week phase II clinical systemic lupus erythematosus trial implicates a mechanism of action through multiple immune-related pathways
Thomas Dörner, Yoshiya Tanaka, M. Petri, J. Smolen +11 more
2020Lupus Science and Medicine57 citations Open access
Semantic Scholar
Gene Expression and Pharmacodynamic Changes in 1,760 Systemic Lupus Erythematosus Patients From Two Phase III Trials of BAFF Blockade With Tabalumab
R. Hoffman, J. Merrill, M. Alarcón-Riquelme, M. Petri +11 more
2016Arthritis & Rheumatology55 citations Open access
Semantic Scholar
A statistical analysis of the TRANSFAC database.
G. Fogel, D. Weekes, G. Varga, E. Dow +5 more
2005Bio Systems55 citations
Semantic Scholar
Mechanism of action of baricitinib and identification of biomarkers and key immune pathways in patients with active systemic lupus erythematosus
Thomas Dörner, Yoshiya Tanaka, E. Dow, A. Koch +6 more
2022Annals of the Rheumatic Diseases50 citations Open access
Semantic Scholar
Differential Effects of Estrogen and Raloxifene on Messenger RNA and Matrix Metalloproteinase 2 Activity in the Rat Uterus
L. M. Helvering, M. D. Adrian, A. Geiser, S. T. Estrem +14 more
2005Biology of Reproduction43 citations
Semantic Scholar
Evolutionary computation for discovery of composite transcription factor binding sites
G. Fogel, V. W. Porto, G. Varga, E. Dow +6 more
2008Nucleic Acids Research33 citations Open access
Semantic Scholar
Automated analysis of proton NMR spectra from combinatorial rapid parallel synthesis using self-organizing maps.
S. Kalelkar, E. Dow, J. Grimes, M. Clapham +1 more
2002Journal of combinatorial chemistry28 citations
Semantic Scholar
Expression Profiling of Rat Femur Revealed Suppression of Bone Formation Genes by Treatment with Alendronate and Estrogen but Not Raloxifenes⃞
L. M. Helvering, Riting Liu, N. Kulkarni, T. Wei +12 more
2005Molecular Pharmacology27 citations
Semantic Scholar
The Janus kinase 1/2 inhibitor baricitinib reduces biomarkers of joint destruction in moderate to severe rheumatoid arthritis
C. Thudium, A. Bay-Jensen, Suntara Cahya, E. Dow +4 more
2020Arthritis Research & Therapy20 citations Open access
Semantic Scholar
Gene Expression and Pharmacodynamic-Induced Changes in 1 , 760 SLE Patients from Two Phase III Trials of B Cell Activating Factor Blockade with Tabalumab
R. Hoffman, J. Merrill, M. Alarcón-Riquelme, M. Petri +11 more
201618 citations
Semantic Scholar
A Bayesian gene network reveals insight into the JAK-STAT pathway in systemic lupus erythematosus
Yupeng Li, R. Higgs, R. Hoffman, E. Dow +7 more
2019PLoS ONE15 citations Open access
Semantic Scholar
Self-Organizing Maps for the Analysis of NMR Spectra
Linda K. Dow, S. Kalelkar, E. Dow
200414 citations
Semantic Scholar
A hybrid self‐organizing maps and particle swarm optimization approach
Xiang Xiao, E. Dow, R. Eberhart, Z. Ben Miled +1 more
2004Concurrency Practice and Experience12 citations
Semantic Scholar
Leveraging health social networking communities in translational research
Y. Webster, E. Dow, Jacob Koehler, R. C. Gudivada +1 more
2011Journal of Biomedical Informatics9 citations Open access
Semantic Scholar
Prediction and analysis of functional RNA structures within the integrative genomics viewer
Warren B Rouse, R. J. Andrews, Nicholas J. Booher, Ji-Bo Wang +4 more
2022NAR Genomics and Bioinformatics8 citations Open access
Semantic Scholar
185 Baricitinib-associated changes in type I interferon gene signature during a 24-week phase 2 clinical SLE trial
T. Dörner, Yoshiya Tanaka, M. Petri, J. Smolen +7 more
2019Abstracts8 citations Open access
Semantic Scholar
IL17A blockade with ixekizumab suppresses MuvB signaling in clinical psoriasis.
S. Ochsner, Mesias Pedroza, R. Pillich, Venkatesh Krishnan +5 more
2023Journal of Investigative Dermatology5 citations Open access
Semantic Scholar
A framework for cross-disciplinary hypothesis generation
Y. Webster, R. C. Gudivada, E. Dow, Jacob Koehler +1 more
2010ACM Symposium on Applied Computing5 citations
Semantic Scholar
Abstracting genes to gene ontology terms allows comparison across multiple species
Amaresh Kumar, S. M. McAhren, A. West, Hong Gao +6 more
2005International Conference on Systems Engineering5 citations
Semantic Scholar
A Hybrid Method to Discover and Rank Cross-Disciplinary Associations
Y. Webster, R. C. Gudivada, E. Dow, Jacob Koehler +1 more
2009IEEE International Conference on Bioinformatics and Biomedicine3 citations
Semantic Scholar
OP0045 DELINEATION OF A PROINFLAMMATORY CYTOKINE PROFILE TARGETED BY JAK1/2 INHIBITION USING BARICITINIB IN A PHASE 2 SLE TRIAL
T. Dörner, Yoshiya Tanaka, M. Petri, J. Smolen +10 more
2020Annals of the Rheumatic Diseases2 citations Open access
Semantic Scholar
AB1372 Towards reforming the taxonomy of human disease: the precisesads cross sectional study
L. Laigle, L. Beretta, J. Wojick, J. Marovac +11 more
2018Validation of outcome measures and biomarkers2 citations Open access
Semantic Scholar
Microarray Pathway Analysis Comparing Baricitinib and Adalimumab in Moderate to Severe Rheumatoid Arthritis Patients, from a Phase 3 Study
P. Emery, P. Taylor, M. Weinblatt, Yoshiya Tanaka +9 more
20172 citations
Semantic Scholar
Modeling Disease In Vivo With
E. Dow
20152 citations
Semantic Scholar
Integrating scientific data for drug discovery and development using the Life Sciences Grid
E. Dow, J. B. Hughes, Susie M. Stephens, Vaibhav A. Narayan +1 more
2009Expert Opinion on Drug Discovery2 citations
Semantic Scholar
03 Affymetrix gene chip analysis of differentially expressed genes in rat post MI CHF model
Jian Wang, L. Gelbert, C. Geringer, G. Cook +7 more
20022 citations
Semantic Scholar
Cellular and proteomic changes following administration of peresolimab in patients with rheumatoid arthritis: a post-hoc analysis of a randomised phase 2a trial.
Robert J. Benschop, J. Tuttle, P. Emery, Christoph Preuss +7 more
2026The Lancet Rheumatology1 citations
Semantic Scholar
O31 Integrative analysis reveals a molecular stratification of systemic autoimmune diseases
G. Barturen, S. Babaei, F. Català-Moll, M. Martínez-Bueno +126 more
2020Oral presentations1 citations Open access
Semantic Scholar
THU0212 BARICITINIB-ASSOCIATED CHANGES IN GLOBAL GENE EXPRESSION DURING A 24-WEEK PHASE 2 CLINICAL SLE TRIAL DESCRIBE A MECHANISM OF ACTION THROUGH INHIBITION OF JAK/STAT AND IFN RESPONSIVE GENE EXPRESSION
T. Dörner, Yoshiya Tanaka, M. Petri, J. Smolen +7 more
2019Poster Presentations1 citations Open access
Semantic Scholar
P092 Microarray pathway analysis comparing baricitinib and adalimumab in moderate to severe rheumatoid arthritis from a phase 3 study
P. Emery, Peter C. Taylor, M. Weinblatt, Yoshiya Tanaka +10 more
20181 citations Open access
Semantic Scholar
OP0079 Pharmacodynamic Changes in Gene Expression Observed in Two Phase 3 Trials of Baff Blockade with Tabalumab in SLE
Robert W. Hoffman, J. Merrill, M. Alarconriquelme, M. Petri +8 more
20151 citations
Semantic Scholar
Identification of a conserved RNA structure in the TNFRSF1A 3’UTR: Implications for post-transcriptional regulation
Van S Tompkins, Warren B Rouse, Ji-Bo Wang, Michael E. Woodman +3 more
2025bioRxiv0 citations Open access
Semantic Scholar
O4 Baricitinib-induced changes in STAT-associated gene expression in systemic lupus erythematosus
T. Dörner, Yoshiya Tanaka, Michelle A. Petri, J. Smolen +11 more
2020Oral presentations0 citations Open access
Semantic Scholar
TRANSCRIPTOME AND METHYLOME INTEGRATIVE MOLECULAR ANALYSIS UNCOVERS A NEW SYSTEMIC AUTOIMMUNE DISEASE CLASSIFICATION
G. Barturen, S. Babaei, F. Català-Moll, Z. Makowska +35 more
20190 citations
Semantic Scholar
S1A:5 Molecular stratification of autoimmune diseases based on epigenetic profiles
G. Barturen, M. Kerick, D. Álvarez-Errico, R. Quintares +15 more
20180 citations Open access
Semantic Scholar
24 A molecular signature based on ifn gene signature and serology defines two populations of patients with different baseline disease activity
M. Petri, K. Kalunian, M. Urowitz, R. Furie +7 more
2017Lupus Science and Medicine0 citations Open access
Semantic Scholar
41 Relevance of mouse lupus models of lupus nephritis to progression of ckd
R. Hoffman, E. Dow, N. Perumal, G. Rocha +6 more
2017Lupus Science and Medicine0 citations Open access
Semantic Scholar
3 Use of Antibiotics and Subsequent Risk of Systemic Lupus Erythematosus : A Matched Case-Control Study
J. Merrill, M. Alarcón-Riquelme, M. Petri, E. Dow +26 more
20150 citations
Semantic Scholar
SAT0005 Human C-Type Lectin Domain Family 4, Member C Gene Expression Level Helps Predict Future Clinical Response to Tabalumab Blockade of Baff in Rheumatoid Arthritis
E. Dow, P. Banerjee, M. Penny, E. Nantz +5 more
20130 citations
Semantic Scholar
Connecting the Bench with the Bedside: Translating Life Science Discoveries to Disease Treatments and Vice Versa
Y. Webster, E. Dow, M. Palakal
20120 citations
Semantic Scholar

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