T. Kawamura

Most-cited papers

1. Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival

   T. Kawamura, M. Kawatani, Makoto Muroi, Y. Kondoh +5 more

   2016Scientific Reports99 citations Open access

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2. Identification of a Small Molecule That Enhances Ferroptosis via Inhibition of Ferroptosis Suppressor Protein 1 (FSP1).

   Hiromasa Yoshioka, T. Kawamura, Makoto Muroi, Y. Kondoh +6 more

   2022ACS Chemical Biology61 citations

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3. SAR Study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation

   T. Kawamura, E. Tashiro, Kohta Yamamoto, K. Shindo +1 more

   2008Journal of antibiotics (Tokyo. 1968)31 citations

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4. Generation of 'Unnatural Natural Product' library and identification of a small molecule inhibitor of XIAP.

   T. Kawamura, K. Matsubara, H. Otaka, E. Tashiro +4 more

   2011Bioorganic & Medicinal Chemistry25 citations Open access

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5. Isolation and structure elucidation of a novel androgen antagonist, arabilin, produced by Streptomyces sp. MK756-CF1

   T. Kawamura, T. Fujimaki, Natsuki Hamanaka, Kentaro Torii +7 more

   2010Journal of antibiotics (Tokyo. 1968)20 citations

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6. SAR Study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation

   T. Kawamura, E. Tashiro, Kohta Yamamoto, K. Shindo +1 more

   2008Journal of antibiotics (Tokyo. 1968)17 citations

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7. A small molecule that induces reactive oxygen species via cellular glutathione depletion.

   T. Kawamura, Y. Kondoh, Makoto Muroi, M. Kawatani +1 more

   2014Biochemical Journal16 citations

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8. Discovery of a σ1 receptor antagonist by combination of unbiased cell painting and thermal proteome profiling.

   Julian Wilke, T. Kawamura, Hao Xu, Alexandra Brause +10 more

   2021Cell Chemical Biology14 citations Open access

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9. Identification and Characterization of an Inhibitor of Trichothecene 3-O-Acetyltransferase, TRI101, by the Chemical Array Approach

   Y. Nakajima, T. Kawamura, K. Maeda, Hinayo Ichikawa +7 more

   2013Bioscience, biotechnology and biochemistry13 citations Open access

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10. Identification and structure–activity relationship of purine derivatives as novel MTH1 inhibitors

    Ashutosh Kumar, T. Kawamura, M. Kawatani, H. Osada +1 more

    2017Chemical Biology and Drug Design12 citations Open access

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11. Identification of cytotoxic, glutathione-reactive moieties inducing accumulation of reactive oxygen species via glutathione depletion.

    Julian Wilke, T. Kawamura, N. Watanabe, H. Osada +2 more

    2017Bioorganic & Medicinal Chemistry8 citations

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12. Identification of a trichothecene production inhibitor by chemical array and library screening using trichodiene synthase as a target protein.

    K. Maeda, Y. Nakajima, T. Motoyama, Y. Kondoh +8 more

    2017Pesticide Biochemistry and Physiology7 citations Open access

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13. A novel inhibitor of tumorspheres reveals the activation of the serine biosynthetic pathway upon mitochondrial inhibition

    Amit Subedi, Makoto Muroi, Y. Futamura, T. Kawamura +5 more

    2019FEBS Letters4 citations Open access

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14. Corrigendum to “Generation of ‘Unnatural Natural Product’ library and identification of a small molecule inhibitor of XIAP” [Bioorg. Med. Chem. 19 (2011) 4377–4385]

    T. Kawamura, K. Matsubara, H. Otaka, E. Tashiro +4 more

    20122 citations Open access

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15. 2141. Preclinical Evaluation of PA-001: A Novel, Potential Macrocyclic Peptide-Based Treatment for COVID-19 Which Binds to the S2 Subunit of SARS-CoV-2 Spike Protein

    T. Kawamura, Masaki Ohuchi, T. Nagasawa, Hirofumi Ohashi +15 more

    2023Open Forum Infectious Diseases1 citations Open access

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16. Chemical Biology of Cell Motility Inhibitors

    T. Kawamura, M. Kitagawa, M. Imoto

    20091 citations

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17. A macrocyclic peptide-based fusion inhibitor targeting SARS-CoV-2 Spike S2 subunit

    Hirofumi Ohashi, T. Kawamura, Masaki Ohuchi, Haruaki Kurasaki +24 more

    2026bioRxiv0 citations

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18. Discovery of small-molecule modulator of heterotrimeric Gi-protein by integrated phenotypic profiling and chemical proteomics

    T. Kawamura, Y. Futamura, Er-Chang Shang, Makoto Muroi +9 more

    2020Bioscience, biotechnology and biochemistry0 citations

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19. 26 NPD926, a small molecule inducer of reactive oxygen species, kills cancer cells via glutathione depletion

    T. Kawamura, Y. Kondoh, Makoto Muroi, M. Kawatani +1 more

    20140 citations

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20. Chemistry and biology of microbial probes modulating ER stress and apoptosis

    T. Kawamura

    20100 citations

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21. Abstract B157: Generation of “Natural Unnatural Product Library” and identification of small molecule XIAP inhibitors

    T. Kawamura, H. Otaka, E. Tashiro, M. Imoto

    20090 citations

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22. 2P206 Interaction between neurites and keratinocytes

    T. Kawamura, R. Suzuki, T. Furuno, M. Nakanishi

    20040 citations Open access

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23. Observation of VAMP protein in PC12 cell using Fluorescence Correlation Spectroscopy

    T. Kawamura, M. Tamura, M. Kinjo

    20010 citations Open access

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