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E. Melloni · SciRah

Researcher profile · Semantic Scholar

E. Melloni

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E. Melloni — researcher profile on SciRah

h-index: 49
Works: 291
Citations: 8,099

Most-cited papers

Inhibition of Calpains Prevents Neuronal and Behavioral Deficits in an MPTP Mouse Model of Parkinson's Disease
S. Crocker, Patrice D. Smith, V. Jackson-Lewis, Wiplore R Lamba +10 more
2003Journal of Neuroscience297 citations Open access
Semantic Scholar
Cutting Edge: Extracellular High Mobility Group Box-1 Protein Is a Proangiogenic Cytokine1
S. Mitola, M. Belleri, C. Urbinati, D. Coltrini +4 more
2006Journal of Immunology147 citations Open access
Semantic Scholar
Activation of Ca2+-dependent proteolysis in skeletal muscle and heart in cancer cachexia
P. Costelli, R. De Tullio, F. Baccino, E. Melloni
2001British Journal of Cancer112 citations Open access
Semantic Scholar
Calpains Mediate p53 Activation and Neuronal Death Evoked by DNA Damage*
Mary Sedarous, Elizabeth Keramaris, M. O'Hare, E. Melloni +4 more
2003Journal of Biological Chemistry110 citations Open access
Semantic Scholar
Glia re‐sealed particles freshly prepared from adult rat brain are competent for exocytotic release of glutamate
S. Stigliani, S. Zappettini, L. Raiteri, M. Passalacqua +6 more
2006Journal of Neurochemistry101 citations Open access
Semantic Scholar
HMGB1 as an autocrine stimulus in human T98G glioblastoma cells: role in cell growth and migration
Rosaria Bassi, P. Giussani, V. Anelli, T. Colleoni +6 more
2008Journal of Neuro-Oncology96 citations
Semantic Scholar
Selective Proinflammatory Activation of Astrocytes by High-Mobility Group Box 1 Protein Signaling1
M. Pedrazzi, M. Patrone, M. Passalacqua, E. Ranzato +4 more
2007Journal of Immunology96 citations Open access
Semantic Scholar
Changes in intracellular calpastatin localization are mediated by reversible phosphorylation.
M. Averna, R. De Tullio, M. Passalacqua, F. Salamino +2 more
2001Biochemical Journal92 citations Open access
Semantic Scholar
The Calpain System Is Involved in the Constitutive Regulation of β-Catenin Signaling Functions*
R. Benetti, T. Copetti, S. Dell'Orso, E. Melloni +3 more
2005Journal of Biological Chemistry84 citations Open access
Semantic Scholar
Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy
Stephen P. Chelko, Gizem Keceli, A. Carpi, N. Doti +22 more
2021Science Translational Medicine83 citations Open access
Semantic Scholar
Changes in intracellular localization of calpastatin during calpain activation.
R. De Tullio, M. Passalacqua, M. Averna, F. Salamino +2 more
1999Biochemical Journal78 citations Open access
Semantic Scholar
Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein
M. Pedrazzi, L. Raiteri, G. Bonanno, M. Patrone +7 more
2006Journal of Neurochemistry76 citations
Semantic Scholar
Acyl-CoA-binding Protein Is a Potent m-Calpain Activator*
E. Melloni, M. Averna, F. Salamino, B. Sparatore +2 more
2000Journal of Biological Chemistry72 citations Open access
Semantic Scholar
3 – Selective Pro-Inflammatory Activation of Astrocytes by High Mobility Group Box 1 Protein Signaling
M. Pedrazzi, E. Melloni, B. Sparatore
201059 citations
Semantic Scholar
Association of Calpastatin with Inactive Calpain
E. Melloni, M. Averna, R. Stifanese, R. De Tullio +3 more
2006Journal of Biological Chemistry56 citations Open access
Semantic Scholar
Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein
M. Pedrazzi, M. Averna, B. Sparatore, M. Patrone +7 more
2012PLoS ONE55 citations Open access
Semantic Scholar
Functional Role of HSP90 Complexes with Endothelial Nitric-oxide Synthase (eNOS) and Calpain on Nitric Oxide Generation in Endothelial Cells*
M. Averna, R. Stifanese, R. De Tullio, M. Passalacqua +3 more
2008Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Characterization of a new p94-like calpain form in human lymphocytes.
R. De Tullio, R. Stifanese, F. Salamino, S. Pontremoli +1 more
2003Biochemical Journal51 citations Open access
Semantic Scholar
Activation of PKC-β isoforms mediates HNE-induced MCP-1 release by macrophages
M. Nitti, C. Domenicotti, C. d'Abramo, S. Assereto +6 more
200248 citations
Semantic Scholar
Adaptive Modifications in the Calpain/Calpastatin System in Brain Cells after Persistent Alteration in Ca2+ Homeostasis*
R. Stifanese, M. Averna, R. De Tullio, M. Pedrazzi +6 more
2009Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Role of PKC-δ activity in glutathione-depleted neuroblastoma cells
C. Domenicotti, B. Marengo, D. Verzola, G. Garibotto +9 more
200346 citations
Semantic Scholar
Changes in calpastatin localization and expression during calpain activation: a new mechanism for the regulation of intracellular Ca2+-dependent proteolysis
M. Averna, R. De Tullio, P. Capini, F. Salamino +2 more
2003Cellular and Molecular Life Sciences (CMLS)40 citations Open access
Semantic Scholar
Age-dependent Degradation of Calpastatin in Kidney of Hypertensive Rats*
M. Averna, R. De Tullio, F. Salamino, R. Minafra +2 more
2001Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Differential degradation of calpastatin by μ‐ and m‐calpain in Ca2+‐enriched human neuroblastoma LAN‐5 cells
R. De Tullio, M. Averna, F. Salamino, S. Pontremoli +1 more
2000FEBS Letters39 citations
Semantic Scholar
Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90
M. Averna, R. Stifanese, R. De Tullio, F. Salamino +3 more
2007The FEBS Journal37 citations Open access
Semantic Scholar
Glycine taken up through GLYT1 and GLYT2 heterotransporters into glutamatergic axon terminals of mouse spinal cord elicits release of glutamate by homotransporter reversal and through anion channels.
L. Raiteri, S. Stigliani, A. Siri, M. Passalacqua +3 more
2005Biochemical Pharmacology37 citations
Semantic Scholar
N,N-dialkylaminosubstituted chromones and isoxazoles as potential anti-inflammatory agents.
M. Mazzei, E. Sottofattori, Ramona Dondero, M. Ibrahim +2 more
1999Il Farmaco36 citations
Semantic Scholar
Stimulation of erythroleukaemia cell differentiation by extracellular high-mobility group-box protein 1 is independent of the receptor for advanced glycation end-products.
B. Sparatore, M. Pedrazzi, M. Passalacqua, Deborah Gaggero +3 more
2002Biochemical Journal33 citations Open access
Semantic Scholar
A novel role of protein kinase C-δ in cell signaling triggered by glutathione depletion
C. Domenicotti, B. Marengo, M. Nitti, D. Verzola +6 more
200330 citations
Semantic Scholar
Regulation of Calpain Activity in Rat Brain with Altered Ca2+ Homeostasis*
M. Averna, R. Stifanese, R. De Tullio, M. Passalacqua +4 more
2007Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Role of calpain-1 in the early phase of experimental ALS.
R. Stifanese, M. Averna, R. De Tullio, M. Pedrazzi +6 more
2014Archives of Biochemistry and Biophysics27 citations
Semantic Scholar
Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation.
B. Sparatore, M. Patrone, M. Passalacqua, Marco Pedrazzi +3 more
2001Biochemical Journal27 citations Open access
Semantic Scholar
Conformational Changes of Calpain from Human Erythrocytes in the Presence of Ca2+ *
E. Dainese, R. Minafra, A. Sabatucci, P. Vachette +2 more
2002Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Effects of calpain inhibition on dopaminergic markers and motor function following intrastriatal 6-hydroxydopamine administration in rats.
R. Grant, Laurie H. L. Sellings, S. Crocker, E. Melloni +2 more
2009Neuroscience25 citations
Semantic Scholar
Multiple rat brain calpastatin forms are produced by distinct starting points and alternative splicing of the N-terminal exons.
R. De Tullio, M. Averna, R. Stifanese, T. Parr +3 more
2007Archives of Biochemistry and Biophysics25 citations
Semantic Scholar
Inhibition of neutrophil O(2)(-) production by unsymmetrical methylene derivatives of benzopyrans: their use as potential antiinflammatory agents.
M. Mazzei, Ramona Dondero, E. Sottofattori, E. Melloni +1 more
2001European journal of medicinal chemistry24 citations
Semantic Scholar
In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS–HSP90 heterocomplex
M. Averna, R. Stifanese, R. De Tullio, F. Salamino +2 more
2008The FEBS Journal23 citations
Semantic Scholar
Role of PKC-delta activity in glutathione-depleted neuroblastoma cells.
C. Domenicotti, B. Marengo, D. Verzola, G. Garibotto +9 more
2003Free Radical Biology & Medicine22 citations
Semantic Scholar
Role of the calpain-calpastatin system in the density-dependent growth arrest.
R. Stifanese, M. Averna, R. De Tullio, F. Salamino +5 more
2008Archives of Biochemistry and Biophysics20 citations
Semantic Scholar
Axonal damage and demyelination in long‐term dorsal root ganglia cultures from a rat model of Charcot–Marie–Tooth type 1A disease
L. Nobbio, G. Gherardi, T. Vigo, M. Passalacqua +5 more
2006European Journal of Neuroscience20 citations
Semantic Scholar
Activation of A431 human carcinoma cell motility by extracellular high-mobility group box 1 protein and epidermal growth factor stimuli.
B. Sparatore, M. Patrone, M. Passalacqua, M. Pedrazzi +3 more
2005Biochemical Journal20 citations Open access
Semantic Scholar
Activation of PKC-beta isoforms mediates HNE-induced MCP-1 release by macrophages.
M. Nitti, C. Domenicotti, C. d'Abramo, S. Assereto +6 more
2002Biochemical and Biophysical Research Communications - BBRC20 citations
Semantic Scholar
Involvement of exon 6-mediated calpastatin intracellular movements in the modulation of calpain activation.
R. De Tullio, C. Cantoni, C. Broggio, Carola Prato +5 more
2009Biochimica et Biophysica Acta19 citations
Semantic Scholar
The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes.
G. Bonanno, L. Raiteri, M. Milanese, S. Zappettini +6 more
2007International review of neurobiology19 citations
Semantic Scholar
Properties and intracellular localization of calpain activator protein.
E. Melloni, R. Minafra, F. Salamino, S. Pontremoli
2000Biochemical and Biophysical Research Communications - BBRC19 citations
Semantic Scholar
Role of calpain in the regulation of CFTR (cystic fibrosis transmembrane conductance regulator) turnover.
M. Averna, R. Stifanese, Raffaella Grosso, M. Pedrazzi +4 more
2010Biochemical Journal18 citations
Semantic Scholar
Effect of extremely low frequency magnetic fields on calpain activation
F. Salamino, R. Minafra, V. Grano, N. Diano +3 more
2006Bioelectromagnetics17 citations
Semantic Scholar
Characterization of the calpain/calpastatin system in human hemopoietic cell lines.
R. Stifanese, M. Averna, F. Salamino, C. Cantoni +4 more
2006Archives of Biochemistry and Biophysics17 citations
Semantic Scholar
Interaction between Calpain-1 and HSP90: New Insights into the Regulation of Localization and Activity of the Protease
M. Averna, R. De Tullio, M. Pedrazzi, M. Bavestrello +4 more
2015PLoS ONE16 citations Open access
Semantic Scholar
Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor Complex
M. Averna, M. Pellegrini, C. Cervetto, M. Pedrazzi +5 more
2015PLoS ONE16 citations Open access
Semantic Scholar

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