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R. Mangat · SciRah

Researcher profile · Semantic Scholar

R. Mangat

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R. Mangat — researcher profile on SciRah

h-index: 13
Works: 49
Citations: 527

Most-cited papers

Diets enriched in trans-11 vaccenic acid alleviate ectopic lipid accumulation in a rat model of NAFLD and metabolic syndrome.
M. Jacome-Sosa, F. Borthwick, R. Mangat, R. Uwiera +7 more
2014Journal of Nutritional Biochemistry69 citations Open access
Semantic Scholar
Chronic dietary n-3 PUFA intervention improves dyslipidaemia and subsequent cardiovascular complications in the JCR:LA- cp rat model of the metabolic syndrome.
Jing Lu, F. Borthwick, Z. Hassanali, Ye Wang +8 more
2011British Journal of Nutrition61 citations Open access
Semantic Scholar
Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR:LA-cp rat
M. Jacome-Sosa, C. Vacca, R. Mangat, A. Diané +10 more
2016Journal of Lipid Research40 citations Open access
Semantic Scholar
Increased risk of cardiovascular disease in Type 1 diabetes: arterial exposure to remnant lipoproteins leads to enhanced deposition of cholesterol and binding to glycated extracellular matrix proteoglycans
R. Mangat, Jenny W. Su, J. Lambert, M. Clandinin +7 more
2011Diabetic Medicine40 citations
Semantic Scholar
Chylomicron and apoB48 metabolism in the JCR:LA corpulent rat, a model for the metabolic syndrome.
R. Mangat, J. Su, Paul G. Scott, James C. Russell +2 more
2007Biochemical Society Transactions39 citations
Semantic Scholar
The Interplay of Obesity, Dyslipidemia and Immune Dysfunction: A Brief Overview on Pathophysiology, Animal Models, and Nutritional Modulation
Y. She, R. Mangat, Sue Tsai, S. Proctor +1 more
2022Frontiers in Nutrition34 citations Open access
Semantic Scholar
Inhibition of phospholipase C-γ1 augments the decrease in cardiomyocyte viability by H2O2
R. Mangat, Tushi Singal, N. Dhalla, P. Tappia
200629 citations
Semantic Scholar
Simvastatin treatment upregulates intestinal lipid secretion pathways in a rodent model of the metabolic syndrome.
F. Borthwick, R. Mangat, S. Warnakula, M. Jacome-Sosa +2 more
2014Atherosclerosis25 citations Open access
Semantic Scholar
Rimonabant-mediated changes in intestinal lipid metabolism and improved renal vascular dysfunction in the JCR:LA-cp rat model of prediabetic metabolic syndrome.
J. Russell, S. Kelly, A. Diané, Ye Wang +4 more
2010American Journal of Physiology - Gastrointestinal and Liver Physiology22 citations
Semantic Scholar
Arterial Retention of Remnant Lipoproteins Ex Vivo Is Increased in Insulin Resistance Because of Increased Arterial Biglycan and Production of Cholesterol-Rich Atherogenic Particles That Can Be Improved by Ezetimibe in the JCR:LA-cp Rat
R. Mangat, S. Warnakula, F. Borthwick, Z. Hassanali +5 more
2012Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease21 citations Open access
Semantic Scholar
ApoA-1 infusion reduces arterial cholesterol and myocardial lesions in a rat model of cardiac dysfunction and insulin resistance.
F. Borthwick, S. Warnakula, R. Mangat, R. Uwiera +8 more
2012Atherosclerosis20 citations
Semantic Scholar
Mechanisms of Comorbidities Associated With the Metabolic Syndrome: Insights from the JCR:LA-cp Corpulent Rat Strain
A. Diané, W. D. Pierce, S. Kelly, Sharon Sokolik +12 more
2016Frontiers in Nutrition15 citations Open access
Semantic Scholar
Low birth weight causes insulin resistance and aberrant intestinal lipid metabolism independent of microbiota abundance in Landrace–Large White pigs
M. Fontaine, A. Diané, Vijay P. Singh, R. Mangat +4 more
2019The FASEB Journal13 citations
Semantic Scholar
Inhibition of phospholipase C-gamma 1 augments the decrease in cardiomyocyte viability by H2O2.
R. Mangat, Tushi Singal, N. Dhalla, P. Tappia
2006American Journal of Physiology. Heart and Circulatory Physiology13 citations
Semantic Scholar
Phospholipid-mediated signaling in diseased myocardium
P. Tappia, Tushi Singal, Melissa R. Dent, G. Asemu +2 more
200611 citations
Semantic Scholar
High Vaccenic Acid Content in Beef Fat Attenuates High Fat and High Carbohydrate Western Diet Induced Changes in Lipid Metabolism and Gut Microbiota in Pigs
Vijay P. Singh, M. Fontaine, R. Mangat, J. Fouhse +3 more
2021Microorganisms10 citations Open access
Semantic Scholar
Intestinal lymphatic HDL miR‐223 and ApoA‐I are reduced during insulin resistance and restored with niacin
R. Mangat, F. Borthwick, Tina Haase, M. Jacome +4 more
2017The FASEB Journal9 citations
Semantic Scholar
Model of intestinal chylomicron over-production and ezetimibe treatment: impact on the retention of cholesterol in arterial vessels.
R. Mangat, S. Warnakula, Wang Ye, James C. Russell +3 more
2010Atherosclerosis Supplements9 citations
Semantic Scholar
Effect of High-Fat and Low-Fat Dairy Products on Cardiometabolic Risk Factors and Immune Function in a Low Birthweight Swine Model of Diet-Induced Insulin Resistance
Y. She, Kun Wang, A. Makarowski, R. Mangat +4 more
2022Frontiers in Nutrition7 citations Open access
Semantic Scholar
Differential expression of hypothalamic, metabolic and inflammatory genes in response to short-term calorie restriction in juvenile obese- and lean-prone JCR rats
A. Diané, W. Pierce, R. Mangat, F. Borthwick +6 more
2015Nutrition & Diabetes7 citations Open access
Semantic Scholar
Gender differences in the cardiac response to dietary conjugated linoleic acid isomers.
P. Tappia, R. Mangat, Cindy A. M. Gabriel, Melissa R. Dent +2 more
2006Canadian Journal of Physiology and Pharmacology7 citations
Semantic Scholar
Preferential deposition of dairy derived fatty acids in muscle tissue is partially due to the upregulation of CD36 in a low-birth-weight swine model.
Kun Wang, Y. She, R. Mangat, A. Makarowski +5 more
2023Journal of Animal Science6 citations Open access
Semantic Scholar
Long-Term Catheterization of the Intestinal Lymph Trunk and Collection of Lymph in Neonatal Pigs.
R. Uwiera, R. Mangat, S. Kelly, T. Uwiera +1 more
2016Journal of Visualized Experiments5 citations Open access
Semantic Scholar
Cardiomyocyte Antihypertrophic Effect of Adipose Tissue Conditioned Medium from Rats and Its Abrogation by Obesity is Mediated by the Leptin to Adiponectin Ratio
S. Bairwa, V. Rajapurohitam, X. Gan, R. Mangat +2 more
2016PLoS ONE4 citations Open access
Semantic Scholar
Chylomicron and apoB 48 metabolism in the JCR : LA corpulent rat , a model for the metabolic syndrome
R. Mangat, J. Su, P. Scott, J. Russell +2 more
20074 citations
Semantic Scholar
Low-fat dairy consumption improves intestinal immune function more than high-fat dairy in a diet-induced swine model of insulin resistance
Y. She, Kun Wang, A. Makarowski, R. Mangat +4 more
2022European Journal of Nutrition2 citations
Semantic Scholar
Increased Arterial Exposure to Remnant Lipoproteins Leads to Enhanced Deposition of Cholesterol and Binding to Glycated Extracellular Matrix Proteoglycans
R. Mangat, Wang Ye, R. Uwiera, D. Vine +2 more
20102 citations
Semantic Scholar
Exploring Increased Intestinal Lipid Absorption and Identifying Strategies to Improve Pork Quality in Low-Birth-Weight Swine
Kun Wang, Y. She, R. Mangat, A. Makarowski +5 more
2021Current Developments in Nutrition1 citations Open access
Semantic Scholar
Niacin modulates the secretion of intestinal lymphatic HDL and associated micro RNA profile in a rat model of insulin resistance
R. Mangat, F. Borthwick, T. Ullrich, D. Vine +1 more
20151 citations
Semantic Scholar
Abstract 629: Niacin Beneficially Alters the Secretion of Intestinal HDL in a Rat Model of Insulin Resistance by Opposing Effects on PPAR Alpha and TNF Alpha
R. Mangat, F. Borthwick, T. Ullrich, M. Jacome +2 more
20141 citations
Semantic Scholar
Emerging pathways in the regulation of whole body cholesterol flux: therapeutic opportunities to target atherosclerosis?1
R. Mangat, S. Proctor
2014Journal of Lipid Research1 citations Open access
Semantic Scholar
Corrigendum: Effect of high-fat and low-fat dairy products on cardiometabolic risk factors and immune function in a low birthweight swine model of diet-induced insulin resistance
Y. She, Kun Wang, A. Makarowski, R. Mangat +4 more
2023Frontiers in Nutrition0 citations Open access
Semantic Scholar
Correction to: Low‑fat dairy consumption improves intestinal immune function more than high‑fat dairy in a diet‑induced swine model of insulin resistance
Y. She, Kun Wang, A. Makarowski, R. Mangat +4 more
2023European Journal of Nutrition0 citations Open access
Semantic Scholar
Corrigendum: The interplay of obesity, dyslipidemia and immune dysfunction: a brief overview on pathophysiology, animal models, and nutritional modulation
Y. She, R. Mangat, Suey-Ling Tsai, Spencer D. Proctor +1 more
2023Frontiers in Nutrition0 citations Open access
Semantic Scholar
Anti-Glycosaminoglycan Monoclonal Antibody Prevents Cardiac Hypertrophy In A Rat Model Of Metabolic Syndrome
Y. Soto, R. Mangat, S. Kelly, A. Vázquez +1 more
2019Atherosclerosis0 citations
Semantic Scholar
03 - ANTI-GLYCOSAMINOGLYCAN MONOCLONAL ANTIBODY PREVENTS CARDIAC HYPERTROPHY IN A RAT MODEL OF METABOLIC SYNDROME
Y. Soto, R. Mangat, S. Kelly, A. Vázquez +1 more
20190 citations
Semantic Scholar
Novel Anti-proteoglycan Antibody Inhibits Arterial Lipoprotein Retention and Prevents Cardiac Hypertrophy in a Rat Model of Insulin Resistance
Y. Soto, R. Mangat, S. Kelly, A. Vázquez +1 more
2018Atherosclerosis Supplements0 citations
Semantic Scholar
Corrigendum to “Diets enriched in trans-11 vaccenic acid alleviate ectopic lipid accumulation in a rat model of NAFLD and metabolic syndrome” [J Nutr Biochem (2014) 692–701]
M. Jacome-Sosa, F. Borthwick, R. Mangat, R. Uwiera +6 more
20160 citations
Semantic Scholar
A NOVEL ANTI-PROTEOGLYCAN ANTIBODY INHIBITS ARTERIAL RETENTION OF REMNANT LIPOPROTEINS IN A RAT MODEL OF INSULIN RESISTANCE
R. Mangat, Y. Soto, A. Vázquez, S. Proctor
20160 citations
Semantic Scholar
Abstract 321: Lymphatic derived HDL Is an Effective Donor for the Trans-Intestinal Cholesterol Efflux Pathway That Is Impaired During Insulin Resistance
R. Mangat, F. Borthwick, D. Vine, S. Proctor
20150 citations
Semantic Scholar
NIACIN ALTERS THE SECRETION OF INTESTINAL LYMPHATIC HDL AND ASSOCIATED MIRNA PROFILE IN A RAT MODEL OF INSULIN RESISTANCE
R. Mangat, F. Borthwick, T. Ullrich, M. Jacome +2 more
20140 citations
Semantic Scholar
Abstract 672: Reduced "Egress" of Remnant Lipoproteins From Arterial Tissue Relative to LDL During Insulin Resistance May Explain a Preferential Role in Atherosclerosis Progression
R. Mangat, F. Borthwick, D. Vine, S. Proctor
2014Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar
Simvastatin and ezetimibe have opposing regulation on intestinal cholesterol absorption and trans intestinal cholesterol excretion (tice) during metabolic syndrome
R. Mangat, F. Borthwick, S. Warnakula, M. Jacome-Sosa +2 more
20140 citations
Semantic Scholar
Abstract 445: Niacin Beneficially Alters the Secretion of Intestinal-derived TRL and HDL in a Rat Model of Insulin Resistance
R. Mangat, F. Borthwick, T. Ullrich, M. Jacome +2 more
20130 citations
Semantic Scholar
The Role of Intestinal Derived Remnant Lipoproteins in the Progression of Atherosclerosis in Animal Models of Type 1 and Type 2 Diabetes.
R. Mangat
20110 citations
Semantic Scholar
Dietary n−3 PUFA Improves Post-Prandial Metabolism by Reducing Chylomicron apoB48 Production and Lymphatic Cholesterol in the Insulin Resistant JCR:LA-cp rat
F. Borthwick, J. Lu, Z. Hassanali, Y. Wang +8 more
20100 citations
Semantic Scholar
Exacerbated production of intestinal lymph chylomicrons is associated with increased intestinal transport of cholesterol during hyper-insulinemia in the JCR:LA-cp rodent
D. Vine, S. Kelly, K. MacNaughton, Z. Hassanali +3 more
20080 citations
Semantic Scholar
Binding of intestinally derived chylomicron-remnants to biglycan is associated with an increased concentration of particle cholesterol compared to low-density lipoprotein
R. Mangat, Wang Ye, K. MacNaughton, R. Uwiera +2 more
20080 citations
Semantic Scholar
Inhibition of phospholipase C- (cid:1) 1 augments the decrease in cardiomyocyte viability by H 2 O 2 of
R. Mangat, Tushi Singal, N. Dhalla, P. Tappia
20060 citations
Semantic Scholar

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