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B. Greenberg · SciRah

Researcher profile · Semantic Scholar

B. Greenberg

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B. Greenberg — researcher profile on SciRah

h-index: 45
Works: 114
Citations: 8,942

Most-cited papers

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation.
J. Milano, J. McKay, C. Dagenais, L. Foster-Brown +6 more
2004Toxicological Sciences614 citations Open access
Semantic Scholar
Potentially amyloidogenic, carboxyl-terminal derivatives of the amyloid protein precursor.
S. Estus, T. E. Golde, T. Kunishita, D. Blades +6 more
1992Science401 citations
Semantic Scholar
Metabolism of the Swedish Amyloid Precursor Protein Variant in Neuro2a (N2a) Cells
G. Thinakaran, D. Teplow, R. Siman, B. Greenberg +1 more
1996Journal of Biological Chemistry341 citations Open access
Semantic Scholar
Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein.
P. Cras, M. Kawai, D. Lowery, P. Gonzalez-DeWhitt +2 more
1991Proceedings of the National Academy of Sciences of the United States of America307 citations Open access
Semantic Scholar
Modulation of Secreted β-Amyloid Precursor Protein and Amyloid β-Peptide in Brain by Cholesterol*
D. S. Howland, S. Trusko, M. Savage, A. Reaume +7 more
1998Journal of Biological Chemistry225 citations Open access
Semantic Scholar
Turnover of Amyloid β-Protein in Mouse Brain and Acute Reduction of Its Level by Phorbol Ester
M. Savage, S. Trusko, D. S. Howland, Leonard R. Pinsker +5 more
1998Journal of Neuroscience219 citations Open access
Semantic Scholar
High affinity interactions between the Alzheimer's beta-amyloid precursor proteins and the basement membrane form of heparan sulfate proteoglycan.
S. Narindrasorasak, D. Lowery, P. Gonzalez-DeWhitt, R. Poorman +2 more
1991Journal of Biological Chemistry207 citations Open access
Semantic Scholar
Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease.
M. Kawai, R. Kalaria, P. Cras, S. Siedlak +5 more
1993Brain Research198 citations
Semantic Scholar
The roles of inflammation and immune mechanisms in Alzheimer's disease
L. V. Van Eldik, M. Carrillo, P. Cole, D. Feuerbach +11 more
2016Alzheimer's & Dementia193 citations Open access
Semantic Scholar
A new A4 amyloid mRNA contains a domain homologous to serine protease inhibitors
P. Ponte, P. Gonzalez-DeWhitt, J. Schilling, J. Miller +7 more
1988185 citations
Semantic Scholar
Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease.
P. Cras, M. Kawai, S. Siedlak, P. Mulvihill +5 more
1990American Journal of Pathology184 citations
Semantic Scholar
Enhanced Amyloidogenic Processing of the β-Amyloid Precursor Protein in Gene-targeted Mice Bearing the Swedish Familial Alzheimer's Disease Mutations and a “Humanized” Aβ Sequence*
A. Reaume, D. S. Howland, S. Trusko, M. Savage +4 more
1996Journal of Biological Chemistry160 citations Open access
Semantic Scholar
Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques.
H. Arai, V. M. Lee, Laszlo Otvos, B. Greenberg +4 more
1990Proceedings of the National Academy of Sciences of the United States of America154 citations Open access
Semantic Scholar
The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells.
S. Kuentzel, S. M. Ali, R. A. Altman, B. Greenberg +1 more
1993Biochemical Journal150 citations Open access
Semantic Scholar
Novel β-Secretase Cleavage of β-Amyloid Precursor Protein in the Endoplasmic Reticulum/Intermediate Compartment of NT2N Cells
A. S. Chyung, B. Greenberg, D. Cook, R. Doms +1 more
1997Journal of Cell Biology148 citations Open access
Semantic Scholar
Morphological and Biochemical Analyses of Amyloid Plaque Core Proteins Purified from Alzheimer Disease Brain Tissue
A. Roher, K. C. Palmer, E. Yurewicz, M. J. Ball +1 more
1993Journal of Neurochemistry148 citations
Semantic Scholar
Linear Non-competitive Inhibition of Solubilized Human γ-Secretase by Pepstatin A Methylester, L685458, Sulfonamides, and Benzodiazepines*
G. Tian, C. Sobotka-Briner, J. Zysk, Xiaodong Liu +5 more
2002Journal of Biological Chemistry144 citations Open access
Semantic Scholar
Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies
D. Shineman, G. Basi, J. L. Bizon, C. Colton +14 more
2011Alzheimer's Research & Therapy137 citations Open access
Semantic Scholar
Characterization of high affinity binding between laminin and Alzheimer's disease amyloid precursor proteins.
S. Narindrasorasak, D. Lowery, R. A. Altman, P. Gonzalez-DeWhitt +2 more
1992Laboratory investigation; a journal of technical methods and pathology133 citations
Semantic Scholar
Diffuse plaques contain C-terminal Aβ42 and not Aβ40: Evidence from cats and dogs
Brian J Cummings, T. Satou, E. Head, N. Milgram +7 more
1996132 citations
Semantic Scholar
Expression patterns of β‐amyloid precursor protein (β‐APP) in neural and nonneural human tissues from alzheimer's disease and control subjects
H. Arai, V. Lee, M. Messinger, B. Greenberg +2 more
1991132 citations
Semantic Scholar
A beta 42 is the predominant form of amyloid beta-protein in the brains of short-term survivors of head injury.
S. Gentleman, B. Greenberg, M. Savage, M. Noori +4 more
1997NeuroReport123 citations
Semantic Scholar
Translational animal models for Alzheimer's disease: An Alzheimer's Association Business Consortium Think Tank
M. Vitek, J. Araujo, M. Fossel, B. Greenberg +11 more
2020Alzheimer's & Dementia99 citations Open access
Semantic Scholar
β‐Amyloid (Aβ)42(43), Aβ42, Aβ40 and apoE immunostaining of plaques in fatal head injury
K. Horsburgh, G. Cole, Fu-Sheng Yang, M. Savage +4 more
2000Neuropathology and Applied Neurobiology82 citations
Semantic Scholar
Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.
A. Tomasselli, John O. Hui, L. Adams, J. Chosay +6 more
1991Journal of Biological Chemistry78 citations Open access
Semantic Scholar
An interaction between basement membrane and Alzheimer amyloid precursor proteins suggests a role in the pathogenesis of Alzheimer's disease.
Suree Narindrasorasak, R. A. Altman, P. Gonzalez-DeWhitt, B. Greenberg +1 more
1995Laboratory investigation; a journal of technical methods and pathology76 citations
Semantic Scholar
Soluble derivatives of the β amyloid protein precursor of Alzheimer's disease are labeled by antisera to the β amyloid protein
M. Palmert, S. Siedlak, M. Podlisny, B. Greenberg +6 more
198975 citations
Semantic Scholar
Binding of vascular heparan sulfate proteoglycan to Alzheimer's amyloid precursor protein is mediated in part by the N-terminal region of A4 peptide.
L. Buée, W. Ding, John P. Anderson, S. Narindrasorasak +6 more
1993Brain Research71 citations
Semantic Scholar
Amyloid precursor protein in senile plaques of Alzheimer disease.
George Perry, S. Lipphardt, M. Kancherla, P. Gambetti +7 more
198871 citations
Semantic Scholar
The Mechanism of γ-Secretase
G. Tian, S. Ghanekar, D. Aharony, A. Shenvi +3 more
2003Journal of Biological Chemistry69 citations Open access
Semantic Scholar
Molecular features of hypothalamic plaques in Alzheimer's disease.
D. Standaert, Virginia M. Y. Lee, B. Greenberg, D. Lowery +1 more
1991American Journal of Pathology67 citations
Semantic Scholar
Basolateral Secretion of Amyloid Precursor Protein in Madin-Darby Canine Kidney Cells Is Disturbed by Alterations of Intracellular pH and by Introducing a Mutation Associated with Familial Alzheimer's Disease (*)
B. de Strooper, K. Craessaerts, I. Dewachter, D. Moechars +3 more
1995Journal of Biological Chemistry65 citations Open access
Semantic Scholar
Subcellular localization of amyloid precursor protein in senile plaques of Alzheimer's disease.
M. Kawai, P. Cras, P. Richey, M. Tabaton +5 more
1992American Journal of Pathology56 citations
Semantic Scholar
Mechanism of γ-secretase cleavage activation: Is γ-secretase regulated through autoinhibition involving the presenilin-1 exon 9 loop?
Katharine S. Knappenberger, G. Tian, Xiaomei Ye, C. Sobotka-Briner +3 more
200453 citations
Semantic Scholar
Diffuse plaques contain C-terminal A beta 42 and not A beta 40: evidence from cats and dogs.
Brian J Cummings, T. Satou, E. Head, N. Milgram +7 more
1996Neurobiology of Aging53 citations
Semantic Scholar
APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology.
B. Greenberg, M. Savage, D. S. Howland, Shujath M. Ali +4 more
1996Neurobiology of Aging51 citations
Semantic Scholar
Synthetic post-translationally modified human Aβ peptide exhibits a markedly increased tendency to form β-pleated sheets in vitro
H. Fabian, G. Szendrei, H. Mantsch, B. Greenberg +1 more
199449 citations Open access
Semantic Scholar
Alzheimer's amyloid precursor protein produced by recombinant baculovirus expression. Proteolytic processing and protease inhibitory properties.
D. Lowery, J. Pasternack, P. Gonzalez-DeWhitt, H. Zurcher-Neely +6 more
1991Journal of Biological Chemistry47 citations Open access
Semantic Scholar
β-Amyloid Peptide and Amyloid Precursor Proteins in Olfactory Mucosa of Patients with Alzheimer's Disease, Parkinson's Disease, and down Syndrome
P. Crino, B. Greenberg, John A. Martin, V. Lee +2 more
199546 citations
Semantic Scholar
Lewy bodies contain beta-amyloid precursor proteins of Alzheimer's disease.
H. Arai, V. Lee, W. D. Hill, B. Greenberg +1 more
1992Brain Research45 citations
Semantic Scholar
Epitope analysis of senile plaque components in the hippocampus of patients with Parkinson's disease
H. Arai, M. L. Schmidt, V. Lee, H. Hurtig +3 more
1992Neurology44 citations
Semantic Scholar
Mutant and native human β-amyloid precursor proteins in transgenic mouse brain
D. S. Howland, M. Savage, F. A. Huntress, R. Wallace +8 more
199543 citations
Semantic Scholar
Immunocytochemical evidence that the beta-protein precursor is an integral component of neurofibrillary tangles of Alzheimer's disease.
George Perry, P. Richey, S. Siedlak, Mark A. Smith +5 more
1993American Journal of Pathology42 citations
Semantic Scholar
Expression patterns of beta-amyloid precursor protein (beta-APP) in neural and nonneural human tissues from Alzheimer's disease and control subjects.
H. Arai, V. Lee, M. Messinger, B. Greenberg +2 more
1991Annals of Neurology41 citations
Semantic Scholar
The amyloid precursor protein of Alzheimer disease is expressed as a 130 kDa polypeptide in various cultured cell types
L. Autilio‐Gambetti, A. Morandi, M. Tabaton, B. Schaetzle +4 more
198841 citations Open access
Semantic Scholar
Cholinesterase activity in the plaques, tangles and angiopathy of Alzheimer's disease does not emanate from amyloid.
C. Geula, B. Greenberg, M.-Marsel Mesulam
1994Brain Research40 citations
Semantic Scholar
Rank-Order of Potencies for Inhibition of the Secretion of Aβ40 and Aβ42 Suggests That Both Are Generated by a Single γ-Secretase*
J. T. Durkin, S. Murthy, E. Husten, S. Trusko +4 more
1999Journal of Biological Chemistry36 citations Open access
Semantic Scholar
Elevated Aβ levels in Alzheimer's disease brain are associated with selective accumulation of Aβ42 in parenchymal amyloid plaques and both Aβ40 and Aβ42 in cerebrovascular deposits
M. Savage, J. Kawooya, Leonard R. Pinsker, T. L. Emmons +3 more
199534 citations
Semantic Scholar
The COOH-terminus of the Alzheimer amyloid Aβ peptide: Differences in length influence the process of amyloid deposition in Alzheimer brain, and tell us something about relationships among parenchymal and vessel-associated amyloid deposits
B. Greenberg
199530 citations
Semantic Scholar
The gene for the serpin thrombin inhibitor (PI7), protease nexin I, is located on human chromosome 2q33-q35 and on syntenic regions in the mouse and sheep genomes.
R. E. Carter, K. Cerosaletti, D. Burkin, R. E. Fournier +4 more
1995Genomics29 citations
Semantic Scholar

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V. Lee — researcher profile on SciRah

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P. Cras — researcher profile on SciRah

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M. Kawai — researcher profile on SciRah

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S. Siedlak — researcher profile on SciRah